erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Recommended treatment schedules for syphilis. | 1976 | Med Times | pmid:979578 | |
Limia A et al. | [Phenotypic characterization of erythromycin resistance in strains of the genus Streptococcus isolated from clinical specimens]. | 1998 | Rev Esp Quimioter | pmid:9795307 |
Bellido JL et al. | [Resistance to macrolides in Streptococcus pyogenes]. | 1998 | Rev Esp Quimioter | pmid:9795305 |
Riippi M et al. | Dependence between dissolution rate and porosity of compressed erythromycin acistrate tablets. | 1998 | Eur J Pharm Biopharm | pmid:9795044 |
Danias PG et al. | Comparative in vitro and in vivo efficacy of roxithromycin and erythromycin against a strain of methicillin-susceptible Staphylococcus epidermidis. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9791758 |
Platonova MM et al. | [Clinical significance of fungal and microbial associations and antibacterial therapy for treatment of chronic inflammatory respiratory tract diseases in children]. | 1998 | Antibiot. Khimioter. | pmid:9791682 |
Kolpakov AI et al. | [Use of exogenous ribonuclease for improvement of Lactobacillus biological properties]. | 1998 | Antibiot. Khimioter. | pmid:9791680 |
Oh TG et al. | Induction of ermAMR from a clinical strain of Enterococcus faecalis by 16-membered-ring macrolide antibiotics. | 1998 | J. Bacteriol. | pmid:9791136 |
Geslin P et al. | [Development of resistance to beta-lactams and other antibiotics of pneumococci isolated from acute otitis media in France: statement of the National Reference Center 1995-1996]. | 1998 | Arch Pediatr | pmid:9789629 |
Klimchuk ND | [The effect of various antibiotics on the formation of typhus antibodies following immunization with typhus vaccine]. | 1978 | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:97881 |
Saenko VF et al. | [The influence of macrolides on the motor function of the gastrointestinal duct]. | 1998 | Klin Khir | pmid:9787571 |
Schülin T et al. | In-vitro activity of the new ketolide antibiotic HMR 3647 against gram-positive bacteria. | 1998 | J. Antimicrob. Chemother. | pmid:9786468 |
Cimolai N | Mycoplasma pneumoniae respiratory infection. | 1998 | Pediatr Rev | pmid:9785929 |
Yanagisawa M et al. | [Effective treatment in combination with erythromycin and cisapride for chronic idiopathic intestinal pseudo-obstruction (CIIP)]. | 1998 | Nihon Shokakibyo Gakkai Zasshi | pmid:9785893 |
Jacobsen JR et al. | Precursor-directed biosynthesis of 12-ethyl erythromycin. | 1998 | Bioorg. Med. Chem. | pmid:9784859 |
Brünker P et al. | Genetic engineering of an industrial strain of Saccharopolyspora erythraea for stable expression of the Vitreoscilla haemoglobin gene (vhb). | 1998 | Microbiology (Reading, Engl.) | pmid:9782491 |
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Rosenthal SL and Freundlich LF | In vitro antibiotic sensitivity of Pasteurella multocida. | 1976 | Health Lab Sci | pmid:977341 |
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Agouridas C et al. | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. | 1998 | J. Med. Chem. | pmid:9767644 |
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Nion I et al. | [Role of intravenous erythromycin in the preparation for endoscopy in case of upper digestive hemorrhage]. | 1998 | Gastroenterol. Clin. Biol. | pmid:9762296 |
GarcÃa-de-Lomas J et al. | A comparative study on the efficacy of the new quinolone alatrofloxacin in the treatment of experimental legionellosis in guinea pigs. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9758285 |
Hoppe JE and Paulus T | Comparison of three media for agar dilution susceptibility testing of Bordetella pertussis using six antibiotics. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9758277 |
Barbanoj MJ et al. | Buspirone plasma concentrations. | 1998 | Clin. Pharmacol. Ther. | pmid:9757159 |
Greenblatt DJ et al. | Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences. | 1998 | Clin. Pharmacol. Ther. | pmid:9757151 |
Esposito S et al. | Erythromycin resistance in group A beta hemolytic streptococcus. | 1998 Nov-Dec | Chemotherapy | pmid:9755297 |
Hamáková K and Danda J | [Treatment of syphilis with other antibiotics than penicillin (author's transl)]. | 1976 | Cesk Dermatol | pmid:975270 |
Igari J et al. | [Antimicrobial activities of roxithromycin against recently obtained clinical isolates]. | 1997 | Jpn J Antibiot | pmid:9743909 |
Somkuti GA et al. | Molecular characterization of the erythromycin resistance plasmid pPV142 from Staphylococcus simulans. | 1998 | FEMS Microbiol. Lett. | pmid:9742700 |
Tsang KW et al. | Clinical profiles of Chinese patients with diffuse panbronchiolitis. | 1998 | Thorax | pmid:9741370 |
Hargreaves CA et al. | Effects of co-trimoxazole, erythromycin, amoxycillin, tetracycline and chloroquine on sperm function in vitro. | 1998 | Hum. Reprod. | pmid:9740442 |
Barg N | Comparison of four antibiotics in a murine model of necrotizing cutaneous infections caused by toxigenic Streptococcus pyogenes and Staphylococcus aureus. | 1998 | J. Antimicrob. Chemother. | pmid:9738847 |
Koch CL et al. | In-vitro antibiotic susceptibility and molecular analysis of anaerobic bacteria isolated in Cape Town, South Africa. | 1998 | J. Antimicrob. Chemother. | pmid:9738844 |
McDougal LK et al. | Detection of Tn917-like sequences within a Tn916-like conjugative transposon (Tn3872) in erythromycin-resistant isolates of Streptococcus pneumoniae. | 1998 | Antimicrob. Agents Chemother. | pmid:9736555 |
Eckardt L et al. | Drug-related torsades de pointes in the isolated rabbit heart: comparison of clofilium, d,l-sotalol, and erythromycin. | 1998 | J. Cardiovasc. Pharmacol. | pmid:9733356 |
Xu QW et al. | Effect of the prokinetic agent, erythromycin, in the Richardson ground squirrel model of cholesterol gallstone disease. | 1998 | Hepatology | pmid:9731548 |
Edelstein PH | Antimicrobial chemotherapy for Legionnaires disease: time for a change. | 1998 | Ann. Intern. Med. | pmid:9729189 |
Kantola T et al. | Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations. | 1998 | Clin. Pharmacol. Ther. | pmid:9728898 |
Varga J and Fodor L | Biochemical characteristics, serogroup distribution, antibiotic susceptibility and age-related significance of Campylobacter strains causing diarrhoea in humans in Hungary. | 1998 | Zentralbl. Bakteriol. | pmid:9728406 |
Tang CM and Macfarlane JT | Early management of younger adults dying of community acquired pneumonia. | 1993 | Respir Med | pmid:9728229 |
Wang RF et al. | Molecular identification of a Stenotrophomonas species used in the bioassay for erythromycin in aquaculture samples. | 1998 | Mol. Cell. Probes | pmid:9727203 |
Kuo WH et al. | Cephalosporin antibiotics accelerate gastric emptying in mice. | 1998 | Dig. Dis. Sci. | pmid:9724153 |
Colsky AS et al. | Analysis of antibiotic susceptibilities of skin wound flora in hospitalized dermatology patients. The crisis of antibiotic resistance has come to the surface. | 1998 | Arch Dermatol | pmid:9722732 |
Paul VK et al. | Erythromycin treatment of pregnant women to reduce the incidence of low birth weight and preterm deliveries. | 1998 | Int J Gynaecol Obstet | pmid:9722132 |
Kessie G et al. | Plasmid profile and antibiotic resistance in coagulase-negative staphylococci isolated from polluted water. | 1998 | J. Appl. Microbiol. | pmid:9721646 |
Reeves AR et al. | Physical-genetic map of the erythromycin-producing organism Saccharopolyspora erythraea. | 1998 | Microbiology (Reading, Engl.) | pmid:9720036 |
Faghih R et al. | Synthesis of 9-deoxo-4''-deoxy-6,9-epoxyerythromycin derivatives: novel and acid-stable motilides. | 1998 | J. Med. Chem. | pmid:9719592 |
Korting HC et al. | Current antimicrobial susceptibility of cutaneous bacteria to first line antibiotics. | 1998 | Int. J. Antimicrob. Agents | pmid:9716294 |
Kent S et al. | T wave alternans associated with HIV cardiomyopathy, erythromycin therapy, and electrolyte disturbances. | 1998 | South. Med. J. | pmid:9715223 |