erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Bacterial Infections D001424 21 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Skin Neoplasms D012878 12 associated lipids
Pleurisy D010998 20 associated lipids
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Heart Failure D006333 36 associated lipids
Osteitis D010000 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Liver Diseases D008107 31 associated lipids
Corneal Diseases D003316 13 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Pancreatitis D010195 10 associated lipids
Hypersensitivity D006967 22 associated lipids
Acne Vulgaris D000152 35 associated lipids
Osteolysis D010014 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Di Sante L et al. pHTβ-promoted mobilization of non-conjugative resistance plasmids from Enterococcus faecium to Enterococcus faecalis. 2017 J. Antimicrob. Chemother. pmid:28645197
Ramos CJ and Antonetti DA The role of small GTPases and EPAC-Rap signaling in the regulation of the blood-brain and blood-retinal barriers. 2017 Tissue Barriers pmid:28632993
Sader HS et al. Antimicrobial Susceptibility Trends among Staphylococcus aureus Isolates from U.S. Hospitals: Results from 7 Years of the Ceftaroline (AWARE) Surveillance Program, 2010 to 2016. 2017 Antimicrob. Agents Chemother. pmid:28630196
Post A et al. Antibiotic susceptibility profiles among Campylobacter isolates obtained from international travelers between 2007 and 2014. 2017 Eur. J. Clin. Microbiol. Infect. Dis. pmid:28623550
Ishikawa Y et al. Inactivation kinetics and residual activity of CYP3A4 after treatment with erythromycin. 2017 Biopharm Drug Dispos pmid:28425104
Rea E and Husbands E Erythromycin: prophylaxis against recurrent small bowel obstruction. 2017 BMJ Support Palliat Care pmid:28356304
Hawkins PA et al. Cross-resistance to lincosamides, streptogramins A and pleuromutilins in Streptococcus agalactiae isolates from the USA. 2017 J. Antimicrob. Chemother. pmid:28333320
Adhikari RP et al. Inducible clindamycin and methicillin resistant Staphylococcus aureus in a tertiary care hospital, Kathmandu, Nepal. 2017 BMC Infect. Dis. pmid:28693489
Wang HK et al. Clinical features and molecular characteristics of childhood community-associated methicillin-resistant Staphylococcus aureus infection in a medical center in northern Taiwan, 2012. 2017 BMC Infect. Dis. pmid:28679429
Haynes KM et al. Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli. 2017 J. Med. Chem. pmid:28650638
Dalal A et al. Interventions for the prevention of recurrent erysipelas and cellulitis. 2017 Cochrane Database Syst Rev pmid:28631307
Štšepetova J et al. Assessment of phenotypic and genotypic antibiotic susceptibility of vaginal Lactobacillus sp. 2017 J. Appl. Microbiol. pmid:28574626
Tanaka Y et al. Applicability of ribosome engineering to vitamin B12 production by Propionibacterium shermanii. 2017 Biosci. Biotechnol. Biochem. pmid:28532245
Demczuk WHB et al. Phylogenetic analysis of emergent Streptococcus pneumoniae serotype 22F causing invasive pneumococcal disease using whole genome sequencing. 2017 PLoS ONE pmid:28531208
Cheled-Shoval S et al. From Cell to Beak: In-Vitro and In-Vivo Characterization of Chicken Bitter Taste Thresholds. 2017 Molecules pmid:28513558
Sato T et al. Mycoplasma bovis isolates from dairy calves in Japan have less susceptibility than a reference strain to all approved macrolides associated with a point mutation (G748A) combined with multiple species-specific nucleotide alterations in 23S rRNA. 2017 Microbiol. Immunol. pmid:28504455
Wozniak A et al. Importance of adhesins in the recurrence of pharyngeal infections caused by Streptococcus pyogenes. 2017 J. Med. Microbiol. pmid:28463664
Pavlova A et al. Toward the rational design of macrolide antibiotics to combat resistance. 2017 Chem Biol Drug Des pmid:28419786
Szczepanska B et al. Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from children and environmental sources in urban and suburban areas. 2017 BMC Microbiol. pmid:28376713
Calle-Miguel L et al. [Resistance rates and phenotypic characterization of Streptococcus pyogenes in a paediatric population in Northern Spain (2005-2015)]. 2017 Rev Esp Quimioter pmid:28233483
Selwood DL Macrocycles, the edge of drug-likeness chemical space or Goldilocks zone? 2017 Chem Biol Drug Des pmid:28205398
Pergola S et al. Genetic diversity and antimicrobial resistance profiles of Campylobacter coli and Campylobacter jejuni isolated from broiler chicken in farms and at time of slaughter in central Italy. 2017 J. Appl. Microbiol. pmid:28194914
Huang YW et al. Overexpression of SmeDEF Efflux Pump Decreases Aminoglycoside Resistance in Stenotrophomonas maltophilia. 2017 Antimicrob. Agents Chemother. pmid:28193669
Ge LL et al. [Antibiotic resistance analysis of isolates from the hospitalized children in Shanxi Children's Hospital from 2012 to 2014]. 2017 Zhonghua Er Ke Za Zhi pmid:28173648
Giguère S Treatment of Infections Caused by Rhodococcus equi. 2017 Vet. Clin. North Am. Equine Pract. pmid:28161038
Wang Y et al. Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance. 2017 Bioorg. Med. Chem. Lett. pmid:28129976
Owen L et al. A Multifactorial Comparison of Ternary Combinations of Essential Oils in Topical Preparations to Current Antibiotic Prescription Therapies for the Control of Acne Vulgaris-Associated Bacteria. 2017 Phytother Res pmid:28124400
Chen K et al. Drug-resistance dynamics of Staphylococcus aureus between 2008 and 2014 at a tertiary teaching hospital, Jiangxi Province, China. 2017 BMC Infect. Dis. pmid:28122513
Berni E et al. Risk of cardiovascular events, arrhythmia and all-cause mortality associated with clarithromycin versus alternative antibiotics prescribed for respiratory tract infections: a retrospective cohort study. 2017 BMJ Open pmid:28115334
Liu J et al. Engineering of an Lrp family regulator SACE_Lrp improves erythromycin production in Saccharopolyspora erythraea. 2017 Metab. Eng. pmid:27794466
Kassem II et al. Antimicrobial-Resistant Campylobacter in Organically and Conventionally Raised Layer Chickens. 2017 Foodborne Pathog. Dis. pmid:27768387
Song KH et al. Characteristics of cefazolin inoculum effect-positive methicillin-susceptible staphylococcus aureus infection in a multicentre bacteraemia cohort. 2017 Eur. J. Clin. Microbiol. Infect. Dis. pmid:27714592
Marlow N et al. The ORACLE Children Study: educational outcomes at 11 years of age following antenatal prescription of erythromycin or co-amoxiclav. 2017 Arch. Dis. Child. Fetal Neonatal Ed. pmid:27515985
Austin BA and Fleischer AB The extinction of topical erythromycin therapy for acne vulgaris and concern for the future of topical clindamycin. 2017 J Dermatolog Treat pmid:27425633
Jakubů V et al. Trends in the Minimum Inhibitory Concentrations of Erythromycin, Clarithromycin, Azithromycin, Ciprofloxacin, and Trimethoprim/Sulfamethoxazole for Strains of Bordetella pertussis isolated in the Czech Republic in 1967-2015. 2017 Cent. Eur. J. Public Health pmid:29346850
Romero L et al. Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. 2017 Cochrane Database Syst Rev pmid:29226307
Argemi X et al. VISLISI trial, a prospective clinical study allowing identification of a new metalloprotease and putative virulence factor from Staphylococcus lugdunensis. 2017 Clin. Microbiol. Infect. pmid:28017792
Ksia S et al. Molecular Characteristics of Erythromycin-Resistant Streptococcus pyogenes Strains Isolated from Children Patients in Tunis, Tunisia. 2017 Microb. Drug Resist. pmid:27991848
Olajuyigbe OO et al. In vitro pharmacological interaction of caffeine and first-line antibiotics is antagonistic against clinically important bacterial pathogens. 2017 Acta Biochim. Pol. pmid:28612062
Pfaller MA et al. Ceftaroline Activity Against Multidrug-Resistant Streptococcus pneumoniae from U.S. Medical Centers (2014) and Molecular Characterization of a Single Ceftaroline Nonsusceptible Isolate. 2017 Microb. Drug Resist. pmid:27918694
Chang KH et al. Comparison of antibiotic regimens in preterm premature rupture of membranes: neonatal morbidity and 2-year follow-up of neurologic outcome. 2017 J. Matern. Fetal. Neonatal. Med. pmid:27687157
Yi M et al. Functional characterization of a common CYP4F11 genetic variant and identification of functionally defective CYP4F11 variants in erythromycin metabolism and 20-HETE synthesis. 2017 Arch. Biochem. Biophys. pmid:28347661
Weber JM et al. Application of In Vitro Transposon Mutagenesis to Erythromycin Strain Improvement in Saccharopolyspora erythraea. 2017 Methods Mol. Biol. pmid:27709581
Duelge KJ et al. An LC-MS/MS method for the determination of antibiotic residues in distillers grains. 2017 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:28415016
Svetlov MS et al. Kinetics of drug-ribosome interactions defines the cidality of macrolide antibiotics. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:29229833
Hong M et al. C-assisted metabolomics analysis reveals the positive correlation between specific erythromycin production rate and intracellular propionyl-CoA pool size in Saccharopolyspora erythraea. 2017 Bioprocess Biosyst Eng pmid:28567527
Na HK et al. Erythromycin infusion prior to endoscopy for acute nonvariceal upper gastrointestinal bleeding: a pilot randomized controlled trial. 2017 Korean J. Intern. Med. pmid:28352063
Li LH et al. [Effect of low dose erythromycin on the proliferation of granulation tissue after tracheal injury]. 2017 Zhonghua Yi Xue Za Zhi pmid:28316160
Fohner AE et al. PharmGKB summary: Macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics. 2017 Pharmacogenet. Genomics pmid:28146011
Michael-Kordatou I et al. On the capacity of ozonation to remove antimicrobial compounds, resistant bacteria and toxicity from urban wastewater effluents. 2017 J. Hazard. Mater. pmid:26947803