erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Van Herwaarden MA et al. | The effect of motilin agonist ABT-229 on gastro-oesophageal reflux, oesophageal motility and lower oesophageal sphincter characteristics in GERD patients. | 2000 | Aliment. Pharmacol. Ther. | pmid:10759625 |
| Ramirez B and Richter JE | Review article: promotility drugs in the treatment of gastro-oesophageal reflux disease. | 1993 | Aliment. Pharmacol. Ther. | pmid:8094981 |
| Catnach SM et al. | Dose-dependent stimulation of gallbladder contraction by intravenous erythromycin in man. | 1993 | Aliment. Pharmacol. Ther. | pmid:8439638 |
| Verhagen MA et al. | Effects of a new motilide, ABT-229, on gastric emptying and postprandial antroduodenal motility in healthy volunteers. | 1997 | Aliment. Pharmacol. Ther. | pmid:9663833 |
| Talley NJ et al. | Failure of a motilin receptor agonist (ABT-229) to relieve the symptoms of functional dyspepsia in patients with and without delayed gastric emptying: a randomized double-blind placebo-controlled trial. | 2000 | Aliment. Pharmacol. Ther. | pmid:11121915 |
| Emmanuel AV et al. | Erythromycin for the treatment of chronic intestinal pseudo-obstruction: description of six cases with a positive response. | 2004 | Aliment. Pharmacol. Ther. | pmid:15023171 |
| Netzer P et al. | Effects of ABT-229, a motilin agonist, on acid reflux, oesophageal motility and gastric emptying in patients with gastro-oesophageal reflux disease. | 2002 | Aliment. Pharmacol. Ther. | pmid:12182748 |
| Athanasakis E et al. | Octreotide enhances the accelerating effect of erythromycin on gastric emptying in healthy subjects. | 2002 | Aliment. Pharmacol. Ther. | pmid:12182757 |
| McCallum RW and Cynshi O | Clinical trial: effect of mitemcinal (a motilin agonist) on gastric emptying in patients with gastroparesis - a randomized, multicentre, placebo-controlled study. | 2007 | Aliment. Pharmacol. Ther. | pmid:17894654 |
| Chen CL et al. | Efficacy of a motilin receptor agonist (ABT-229) for the treatment of gastro-oesophageal reflux disease. | 2002 | Aliment. Pharmacol. Ther. | pmid:11929393 |
| Winstead NS and Wilcox CM | Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage: a cost-effectiveness analysis. | 2007 | Aliment. Pharmacol. Ther. | pmid:17848180 |
| Brand RM et al. | Transdermal delivery of erythromycin lactobionate--implications for the therapy of gastroparesis. | 1997 | Aliment. Pharmacol. Ther. | pmid:9218087 |
| Annese V et al. | Cisapride and erythromycin prokinetic effects in gastroparesis due to type 1 (insulin-dependent) diabetes mellitus. | 1997 | Aliment. Pharmacol. Ther. | pmid:9218089 |
| van Erpecum KJ et al. | Review article: agents affecting gall-bladder motility--role in treatment and prevention of gallstones. | 2000 | Aliment. Pharmacol. Ther. | pmid:10903008 |
| Chiba T et al. | Motilides accelerate regional gastrointestinal transit in the dog. | 2000 | Aliment. Pharmacol. Ther. | pmid:10886053 |
| Landry C et al. | Could oral erythromycin optimize high energy continuous enteral nutrition? | 1996 | Aliment. Pharmacol. Ther. | pmid:8971296 |
| Ehrenpreis ED et al. | Which form of erythromycin should be used to treat gastroparesis? A pharmacokinetic analysis. | 1998 | Aliment. Pharmacol. Ther. | pmid:9690728 |
| Curry JI et al. | Review article: erythromycin as a prokinetic agent in infants and children. | 2001 | Aliment. Pharmacol. Ther. | pmid:11328252 |
| Kendall BJ et al. | The effect of intravenous erythromycin on solid meal gastric emptying in patients with chronic symptomatic post-vagotomy-antrectomy gastroparesis. | 1997 | Aliment. Pharmacol. Ther. | pmid:9146779 |
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