erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Neuroaspergillosis D020953 2 associated lipids
Common Cold D003139 2 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Uterine Cervical Erosion D002579 2 associated lipids
Animal Diseases D000820 2 associated lipids
Tooth Diseases D014076 2 associated lipids
Torsades de Pointes D016171 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Carbonell N et al. Erythromycin infusion prior to endoscopy for acute upper gastrointestinal bleeding: a randomized, controlled, double-blind trial. 2006 Am. J. Gastroenterol. pmid:16771939
Maganti K et al. Oral erythromycin and symptomatic relief of gastroparesis: a systematic review. 2003 Am. J. Gastroenterol. pmid:12591038
Janssen P et al. The relation between symptom improvement and gastric emptying in the treatment of diabetic and idiopathic gastroparesis. 2013 Am. J. Gastroenterol. pmid:24005344
DITTLER EL Upper abdominal pain and intrahepatic cholestasis as manifestations of sensitivity to ilosone. 1962 Am. J. Gastroenterol. pmid:14028076
Hakkal HG Pseudomembraneous colitis associated with antibiotics. 1976 Am. J. Gastroenterol. pmid:1274934
Jones KL et al. The effect of erythromycin on gastric emptying is modified by physiological changes in the blood glucose concentration. 1999 Am. J. Gastroenterol. pmid:10445530
Rayner CK et al. The stimulation of antral motility by erythromycin is attenuated by hyperglycemia. 2000 Am. J. Gastroenterol. pmid:11007223
Resnick J et al. Delayed gastric emptying and postoperative ileus after nongastric abdominal surgery: part II. 1997 Am. J. Gastroenterol. pmid:9177505
Keshavarzian A and Isaac RM Erythromycin accelerates gastric emptying of indigestible solids and transpyloric migration of the tip of an enteral feeding tube in fasting and fed states. 1993 Am. J. Gastroenterol. pmid:8424419
Mantides A et al. The effect of erythromycin in gastric emptying of solids and hypertonic liquids in healthy subjects. 1993 Am. J. Gastroenterol. pmid:8424420
Richards RD et al. The treatment of idiopathic and diabetic gastroparesis with acute intravenous and chronic oral erythromycin. 1993 Am. J. Gastroenterol. pmid:8424421
Bonacini M et al. Effect of intravenous erythromycin on postoperative ileus. 1993 Am. J. Gastroenterol. pmid:8424422
Weber FH et al. Erythromycin: a motilin agonist and gastrointestinal prokinetic agent. 1993 Am. J. Gastroenterol. pmid:8470625
McNulty CA The treatment of Campylobacter-associated gastritis. 1987 Am. J. Gastroenterol. pmid:3493685
Koutsoumbi P et al. The effect of erythromycin on human esophageal motility is mediated by serotonin receptors. 2000 Am. J. Gastroenterol. pmid:11151866
Portincasa P et al. The effect of acute oral erythromycin on gallbladder motility and on upper gastrointestinal symptoms in gastrectomized patients with and without gallstones: a randomized, placebo-controlled ultrasonographic study. 2000 Am. J. Gastroenterol. pmid:11151875
Ecker JA et al. Pseudomembraneous enterocolitis--an unwelcome gastrointestinal complication of antibiotic therapy. 1970 Am. J. Gastroenterol. pmid:4319211
Kalkay MN et al. Campylobacter-induced toxic megacolon. 1983 Am. J. Gastroenterol. pmid:6613968
Tanaka M et al. Agranulocytosis induced by macrolide antibiotics. 1995 Am. J. Hematol. pmid:7847332
Singer DR et al. Drug hypersensitivity causing granulomatous interstitial nephritis. 1988 Am. J. Kidney Dis. pmid:3354573
Martínez-Maldonado M Postinfectious glomerulonephritis. 2000 Am. J. Kidney Dis. pmid:10636819
Mery JP and Kanfer A Alterations in pharmacokinetics and ototoxicity of erythromycin in renal failure. 1984 Am. J. Kidney Dis. pmid:6741942
Silang R et al. Prokinetic agents increase plasma albumin in hypoalbuminemic chronic dialysis patients with delayed gastric emptying. 2001 Am. J. Kidney Dis. pmid:11157368
Ross EA and Koo LC Improved nutrition after the detection and treatment of occult gastroparesis in nondiabetic dialysis patients. 1998 Am. J. Kidney Dis. pmid:9428453
Ragosta M et al. Potentially fatal interaction between erythromycin and disopyramide. 1989 Am. J. Med. pmid:2467560
Gumaste VV Erythromycin-induced pancreatitis. 1989 Am. J. Med. pmid:2729328
Curtis LH et al. Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients. 2003 Am. J. Med. pmid:12586234
Nattel S et al. Erythromycin-induced long QT syndrome: concordance with quinidine and underlying cellular electrophysiologic mechanism. 1990 Am. J. Med. pmid:2382671
Klein JO Emerging perspectives in management and prevention of infections of the respiratory tract in infants and children. 1985 Am. J. Med. pmid:4014286
Rudin JE et al. Failure of erythromycin in treatment of Legionella micdadei pneumonia. 1984 Am. J. Med. pmid:6607673
Diehl AM et al. Cholestatic hepatitis from erythromycin ethylsuccinate. Report of two cases. 1984 Am. J. Med. pmid:6609640
Parker RH et al. Erythromycin-resistant pneumococcal osteomyelitis. 1970 Am. J. Med. pmid:5415405
Sacristán JA and Soto J Erythromycin ototoxicity: methodology and conclusions. 1993 Am. J. Med. pmid:8430720
Wong KF et al. Psittacosis-associated hemophagocytic syndrome. 1991 Am. J. Med. pmid:1867249
Tablan OC and Reyes MP Chronic interstitial pulmonary fibrosis following Mycoplasma pneumoniae pneumonia. 1985 Am. J. Med. pmid:4025379
DAVIS DS and ROMANSKY MJ Successful treatment of gonococcic endocarditis with erythromycin; review of the literature. 1956 Am. J. Med. pmid:13354638
Augenbraun MH et al. Chlamydia pneumoniae pneumonia with pleural effusion: diagnosis by culture. 1991 Am. J. Med. pmid:1951390
Swanson DJ et al. Erythromycin ototoxicity: prospective assessment with serum concentrations and audiograms in a study of patients with pneumonia. 1992 Am. J. Med. pmid:1731511
Kugler JW et al. Nosocomial Legionnaires' disease. Occurrence in recipients of bone marrow transplants. 1983 Am. J. Med. pmid:6337488
Hopkins S Clinical toleration and safety of azithromycin. 1991 Am. J. Med. pmid:1656742
Friedland L et al. Ocular and pericardial involvement in Legionnaires' disease. 1984 Am. J. Med. pmid:6507461
Schentag JJ and Ballow CH Tissue-directed pharmacokinetics. 1991 Am. J. Med. pmid:1656743
Bolton WK et al. Ventriculojugular shunt nephritis with Corynebacterium bovis. Successful therapy with antibiotics. 1975 Am. J. Med. pmid:1163549
Quintiliani R and Hymans PJ The association of bacteremic Haemophilus influenzae pneumonia in adults with typable strains. 1971 Am. J. Med. pmid:5314534
Stocks JM et al. Ofloxacin in community-acquired lower respiratory infections. A comparison with amoxicillin or erythromycin. 1989 Am. J. Med. pmid:2690620
Watanakunakorn C Clindamycin therapy of Staphylococcus aureus endocarditis. Clinical relapse and development of resistance to clindamycin, lincomycin and erythromycin. 1976 Am. J. Med. pmid:1045861
Bowler WA et al. Gastrointestinal side effects of intravenous erythromycin: incidence and reduction with prolonged infusion time and glycopyrrolate pretreatment. 1992 Am. J. Med. pmid:1546723
Bor DH and Himmelstein DU Endocarditis prophylaxis for patients with mitral valve prolapse. A quantitative analysis. 1984 Am. J. Med. pmid:6711576
Unertl KE et al. Ciprofloxacin in the treatment of legionellosis in critically ill patients including those cases unresponsive to erythromycin. 1989 Am. J. Med. pmid:2589356
Trimble GX Acute pancreatitis induced by erythromycin. 1989 Am. J. Med. pmid:2589410