| MeSH term | MeSH ID | Detail |
|---|---|---|
| Nervous System Diseases | D009422 | 37 associated lipids |
| Enterocolitis, Pseudomembranous | D004761 | 8 associated lipids |
| Ataxia | D001259 | 20 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Urinary Tract Infections | D014552 | 11 associated lipids |
| Cross Infection | D003428 | 9 associated lipids |
| Pseudomonas Infections | D011552 | 25 associated lipids |
| Staphylococcal Skin Infections | D013207 | 9 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
| Bacteriuria | D001437 | 7 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fayer R and Ellis W | Glycoside antibiotics alone and combined with tetracyclines for prophylaxis of experimental cryptosporidiosis in neonatal BALB/c mice. | 1993 | J. Parasitol. | pmid:8392541 |
| Sanz A et al. | Extraction-spectrofluorimetric method for the determination of erythromycin and its esters in pharmaceutical formulations using manual and flow-injection procedures. | 1993 | Analyst | pmid:8391764 |
| Vargas SL et al. | Azithromycin for treatment of severe Cryptosporidium diarrhea in two children with cancer. | 1993 | J. Pediatr. | pmid:8391567 |
| Rodewald LE and Pichichero ME | Compliance with antibiotic therapy: a comparison of deuterium oxide tracer, urine bioassay, bottle weights, and parental reports. | 1993 | J. Pediatr. | pmid:8391566 |
| Ghali R et al. | Erythromycin-associated ergotamine intoxication: arteriographic and electrophysiologic analysis of a rare cause of severe ischemia of the lower extremities and associated ischemic neuropathy. | 1993 | Ann Vasc Surg | pmid:8391300 |
| McDonald PJ et al. | Persistent effect of antibiotics on Staphylococcus aureus after exposure for limited periods of time. | 1977 | J. Infect. Dis. | pmid:839090 |
| Gordillo ME et al. | In vitro activity of azithromycin against bacterial enteric pathogens. | 1993 | Antimicrob. Agents Chemother. | pmid:8390813 |
| Bonnet M and Van der Auwera P | Preincubation of Haemophilus influenzae with subinhibitory concentrations of macrolides: influence on human neutrophil chemiluminescence. | 1993 | Antimicrob. Agents Chemother. | pmid:8390808 |
| Ikerd TR and Koletar SL | In-vitro activity of ciprofloxacin, temafloxacin, azithromycin, clarithromycin and metronidazole against Giardia lamblia. | 1993 | J. Antimicrob. Chemother. | pmid:8390436 |
| Minguez F et al. | In vitro killing kinetics and postantibiotic effect of josamycin and other macrolides on several bacteria. | 1993 May-Jun | Chemotherapy | pmid:8389685 |
| Melski JW et al. | Primary and secondary erythema migrans in central Wisconsin. | 1993 | Arch Dermatol | pmid:8389536 |
| Hammerschlag MR et al. | Single dose of azithromycin for the treatment of genital chlamydial infections in adolescents. | 1993 | J. Pediatr. | pmid:8388950 |
| Malanoski GJ et al. | Effect of pH variation on the susceptibility of Helicobacter pylori to three macrolide antimicrobial agents and temafloxacin. | 1993 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8388791 |
| Cameron DJ | Effectiveness of early Lyme disease treatment. | 1993 | Am. J. Med. | pmid:8388627 |
| Kobrehel G et al. | Erythromycin series. IV. Thin-layer chromatography of erythromycin, erythromycin oxime, erythromyclamine and their acyl derivatives. | 1977 | J. Chromatogr. | pmid:838822 |
| Wildfeuer A et al. | Uptake and subcellular distribution of azithromycin in human phagocytic cells. Demonstration of the antibiotic in neutrophil polymorphonuclear leucocytes and monocytes by autoradiography and electron microscopy. | 1993 | Arzneimittelforschung | pmid:8388213 |
| Strle F et al. | Azithromycin versus doxycycline for treatment of erythema migrans: clinical and microbiological findings. | 1993 Mar-Apr | Infection | pmid:8387966 |
| Donadio S and Staver MJ | IS1136, an insertion element in the erythromycin gene cluster of Saccharopolyspora erythraea. | 1993 | Gene | pmid:8386127 |
| Hammerschlag MR | Azithromycin and clarithromycin. | 1993 | Pediatr Ann | pmid:8385308 |
| Butler T and Girard AE | Comparative efficacies of azithromycin and ciprofloxacin against experimental Salmonella typhimurium infection in mice. | 1993 | J. Antimicrob. Chemother. | pmid:8385094 |
| Brown ST et al. | Azithromycin, rifabutin, and rifapentine for treatment and prophylaxis of Mycobacterium avium complex in rats treated with cyclosporine. | 1993 | Antimicrob. Agents Chemother. | pmid:8384809 |
| Morandini G et al. | Clinical efficacy of azithromycin in lower respiratory tract infections. | 1993 | J Chemother | pmid:8384658 |
| Vaara M | Outer membrane permeability barrier to azithromycin, clarithromycin, and roxithromycin in gram-negative enteric bacteria. | 1993 | Antimicrob. Agents Chemother. | pmid:8383945 |
| Nahata MC et al. | Pharmacokinetics of azithromycin in pediatric patients after oral administration of multiple doses of suspension. | 1993 | Antimicrob. Agents Chemother. | pmid:8383944 |
| Wyrick PB et al. | In-vitro activity of azithromycin on Chlamydia trachomatis infected, polarized human endometrial epithelial cells. | 1993 | J. Antimicrob. Chemother. | pmid:8383102 |
| Spangler SK and Appelbaum PC | Oxyrase, a method which avoids CO2 in the incubation atmosphere for anaerobic susceptibility testing of antibiotics affected by CO2. | 1993 | J. Clin. Microbiol. | pmid:8381817 |
| Steele RJ and Meyer DR | Nasolacrimal duct obstruction and acute dacryocystitis associated with infectious mononucleosis (Epstein-Barr virus) | 1993 | Am. J. Ophthalmol. | pmid:8381586 |
| Holdcroft C | Two new macrolide antibiotics: clarithromycin and azithromycin. | 1993 | Nurse Pract | pmid:8380492 |
| Yamashita K et al. | Sensitive high-performance liquid chromatographic determination of EM523, a new erythromycin derivative, in human plasma and urine with ultraviolet detection using column switching. | 1993 | J. Chromatogr. | pmid:8376485 |
| Morgan AJ and Winters C | Immunolocalization of metallothionein (MT), and X.R.M.A. localization of zinc in hamster skin. | 1993 | Cell Biol. Int. | pmid:8374604 |
| Tomomasa T et al. | Erythromycin increases gastric antral motility in human premature infants. | 1993 | Biol. Neonate | pmid:8373908 |
| Culbertson WW et al. | Effective treatment of phlyctenular keratoconjunctivitis with oral tetracycline. | 1993 | Ophthalmology | pmid:8371924 |
| Hill AD et al. | Erythromycin improves emptying of the denervated stomach after oesophagectomy. | 1993 | Br J Surg | pmid:8369924 |
| Kaufman HS et al. | The effect of erythromycin on motility of the duodenum, sphincter of Oddi, and gallbladder in the prairie dog. | 1993 | Surgery | pmid:8367809 |
| Hocking MP | Postoperative gastroparesis and tachygastria--response to electric stimulation and erythromycin. | 1993 | Surgery | pmid:8367808 |
| Chen SC et al. | Susceptibility of Legionella species to antimicrobial agents. | 1993 | Pathology | pmid:8367199 |
| Colman G et al. | The serotypes of Streptococcus pyogenes present in Britain during 1980-1990 and their association with disease. | 1993 | J. Med. Microbiol. | pmid:8366514 |
| Bannatyne RM and Randall C | Ecology of 350 isolates of group F Streptococcus. | 1977 | Am. J. Clin. Pathol. | pmid:836625 |
| de Champs CL et al. | Selective digestive decontamination by erythromycin-base in a polyvalent intensive care unit. | 1993 | Intensive Care Med | pmid:8366226 |
| Sacristán JA et al. | Erythromycin-induced hypoacusis: 11 new cases and literature review. | 1993 Jul-Aug | Ann Pharmacother | pmid:8364281 |
| Knapp JS et al. | In vitro susceptibilities of isolates of Haemophilus ducreyi from Thailand and the United States to currently recommended and newer agents for treatment of chancroid. | 1993 | Antimicrob. Agents Chemother. | pmid:8363390 |
| Carson JL et al. | Acute liver disease associated with erythromycins, sulfonamides, and tetracyclines. | 1993 | Ann. Intern. Med. | pmid:8363168 |
| Stenberg K and MÃ¥rdh PA | Treatment of concomitant eye and genital chlamydial infection with erythromycin and roxithromycin. | 1993 | Acta Ophthalmol (Copenh) | pmid:8362632 |
| Darelid J et al. | Erythromycin treatment is beneficial for longstanding Moraxella catarrhalis associated cough in children. | 1993 | Scand. J. Infect. Dis. | pmid:8362228 |
| Holmberg RE et al. | Nosocomial Legionella pneumonia in the neonate. | 1993 | Pediatrics | pmid:8361801 |
| Ismaeel NA | In vitro susceptibility of Haemophilus ducreyi to several antibiotics. | 1993 | Microbios | pmid:8361391 |
| Back NA et al. | Recurrent epidemics caused by a single strain of erythromycin-resistant Staphylococcus aureus. The importance of molecular epidemiology. | 1993 | JAMA | pmid:8360968 |
| Higa F et al. | Influence of methylprednisolone on the intracellular antimicrobial activity of erythromycin and clindamycin against Legionella pneumophila. | 1993 | J. Antimicrob. Chemother. | pmid:8360127 |
| Watanabe Y et al. | Chemical modification of erythromycins. XII. A facile synthesis of clarithromycin (6-O-methylerythromycin A) via 2'-silylethers of erythromycin A derivatives. | 1993 | J. Antibiot. | pmid:8360112 |
| Karmody CS and Weinstein L | Reversible sensorineural hearing loss with intravenous erythromycin lactobionate. | 1977 Jan-Feb | Ann. Otol. Rhinol. Laryngol. | pmid:835977 |
| Wilmer A et al. | 5-hydroxytryptamine-3 receptors are involved in the initiation of gastric phase-3 motor activity in humans. | 1993 | Gastroenterology | pmid:8359648 |
| Pawlik WW et al. | Microcirculatory and motor effects of endogenous nitric oxide in the rat gut. | 1993 | J. Physiol. Pharmacol. | pmid:8358050 |
| Bannam TL and Rood JI | Clostridium perfringens-Escherichia coli shuttle vectors that carry single antibiotic resistance determinants. | 1993 | Plasmid | pmid:8356117 |
| Helovuo H et al. | Changes in the prevalence of subgingival enteric rods, staphylococci and yeasts after treatment with penicillin and erythromycin. | 1993 | Oral Microbiol. Immunol. | pmid:8355988 |
| Pellegrini F et al. | [Boutonneuse fever in childhood: a pathology often underdiagnosed. A report of 2 clinical cases]. | 1993 | Minerva Pediatr. | pmid:8355646 |
| Bologna SD et al. | Down-regulation of motilin receptors on rabbit colon myocytes by chronic oral erythromycin. | 1993 | J. Pharmacol. Exp. Ther. | pmid:8355213 |
| Beck DE and Karulf RE | Laparoscopic-assisted full-thickness endoscopic polypectomy. | 1993 | Dis. Colon Rectum | pmid:8348855 |
| Rockwood RP and Embardo LS | Theophylline, ciprofloxacin, erythromycin: a potentially harmful regimen. | 1993 | Ann Pharmacother | pmid:8347920 |
| Donadio S et al. | An erythromycin analog produced by reprogramming of polyketide synthesis. | 1993 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8346223 |
| Arisoy ES et al. | Corynebacterium xerosis ventriculoperitoneal shunt infection in an infant: report of a case and review of the literature. | 1993 | Pediatr. Infect. Dis. J. | pmid:8345988 |
| Heininger U et al. | Clinical and laboratory diagnosis of pertussis in the regions of a large vaccine efficacy trial in Germany. | 1993 | Pediatr. Infect. Dis. J. | pmid:8345982 |
| Guggenbichler JP and Berger H | [Mycoplasma pneumonias in childhood (author's transl)]. | 1977 | Padiatr Padol | pmid:834454 |
| Genetello C et al. | Ti plasmids of Agrobacterium as conjugative plasmids. | 1977 | Nature | pmid:834309 |
| Pennathur A et al. | Erythromycin, motilin, and the esophagus. | 1993 | Surgery | pmid:8342132 |
| Parish LC | Clarithromycin in the treatment of skin and skin structure infections: two multicenter clinical studies. Clarithromycin Study Group. | 1993 | Int. J. Dermatol. | pmid:8340194 |
| Bhatia V and Broor SL | Erythromycin and the gallbladder. | 1993 | Indian J Gastroenterol | pmid:8340147 |
| Xia AF | [Effect of oculentum erythromycin in the prevention of inflammatory conjunctivitis of neonates]. | 1993 | Zhonghua Hu Li Za Zhi | pmid:8339361 |
| Clarke CR et al. | Distribution of intramuscularly administered erythromycin into subcutaneous tissue chambers before and after inoculation with Pasteurella haemolytica. | 1993 | Res. Vet. Sci. | pmid:8337485 |
| Sakito O et al. | [Effect of erythromycin on neutrophil chemotactic activity from human monocytes]. | 1993 | Kansenshogaku Zasshi | pmid:8336016 |
| Biron CR | Erythromycin. | 1993 | RDH | pmid:8332759 |
| Lazarevski T et al. | Erythromycin series. V. Quantitative analysis of cladinose and methylcladinoside by densitometry of thin-layer chromatograms. | 1977 | J. Chromatogr. | pmid:833239 |
| Marosvári I et al. | [Polyresistant Streptococcus pneumoniae causing cumulative diseases in infants and young children]. | 1993 | Orv Hetil | pmid:8332361 |
| Osborne ML and Wall M | Clinical problem-solving: too old for what? | 1993 | N. Engl. J. Med. | pmid:8332170 |
| Cook CS et al. | Involvement of cytochrome P-450IIIA in metabolism of potassium canrenoate to an epoxide: mechanism of inhibition of the epoxide formation by spironolactone and its sulfur-containing metabolite. | 1993 | J. Pharmacol. Exp. Ther. | pmid:8331551 |
| Mollet B et al. | Directed genomic integration, gene replacement, and integrative gene expression in Streptococcus thermophilus. | 1993 | J. Bacteriol. | pmid:8331064 |
| Winkler VW and Nyman MA | Collaborative study of assay method for erythromycin in pelleted feeds containing binding agents. | 1977 | J Assoc Off Anal Chem | pmid:833094 |
| Edelstein PH | Legionnaires' disease. | 1993 | Clin. Infect. Dis. | pmid:8329504 |
| Stjernquist-Desatnik A et al. | Penetration of penicillin V to tonsillar surface fluid in healthy individuals and in patients with acute tonsillitis. | 1993 | J Laryngol Otol | pmid:8320515 |
| DeMarco MJ et al. | Epithelioid angiomatosis. | 1993 Jan-Feb | J Foot Ankle Surg | pmid:8318957 |
| Narita N | [Recent progress on diagnosis and therapy of diffuse panbronchiolitis]. | 1993 | Nippon Naika Gakkai Zasshi | pmid:8315323 |
| Chaussade S et al. | Motilin agonist erythromycin increases human lower esophageal sphincter pressure by stimulation of cholinergic nerves. | 1994 | Dig. Dis. Sci. | pmid:8313822 |
| Sugiyama Y | Diffuse panbronchiolitis. | 1993 | Clin. Chest Med. | pmid:8313679 |
| Kane MP et al. | Stability of erythromycin lactobionate in peritoneal dialysate solutions. | 1994 | Perit Dial Int | pmid:8312421 |
| László P et al. | [Toxic hearing damage caused by antibiotics]. | 1977 | Orv Hetil | pmid:831200 |
| Jarvis BW and Hutchinson CR | Purification of a thymidine-diphospho-4-keto-6-deoxy-D-glucose epimerase from an erythromycin-producing strain of Saccharopolyspora erythraea. | 1994 | Arch. Biochem. Biophys. | pmid:8311450 |
| Pennathur A et al. | Erythromycin strengthens the defective lower esophageal sphincter in patients with gastroesophageal reflux disease. | 1994 | Am. J. Surg. | pmid:8311129 |
| Bausch LC | Newborn eye prophylaxis--where are we now? | 1993 | Nebr Med J | pmid:8309491 |
| Mills OH and Kligman AM | Treatment of acne vulgaris with topically applied erythromycin and tretinoin. | 1978 | Acta Derm. Venereol. | pmid:83088 |
| Hojo M et al. | Erythromycin does not directly affect neutrophil functions. | 1994 | Chest | pmid:8306756 |
| Gitler B et al. | Torsades de pointes induced by erythromycin. | 1994 | Chest | pmid:8306730 |
| Kirst HA | Semi-synthetic derivatives of erythromycin. | 1993 | Prog Med Chem | pmid:8303037 |
| Hsieh YJ and Kolattukudy PE | Inhibition of erythromycin synthesis by disruption of malonyl-coenzyme A decarboxylase gene eryM in Saccharopolyspora erythraea. | 1994 | J. Bacteriol. | pmid:8300527 |
| Erbas T et al. | Comparison of metoclopramide and erythromycin in the treatment of diabetic gastroparesis. | 1993 | Diabetes Care | pmid:8299441 |
| Peeters TL et al. | The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8297350 |
| Meheus A and Piot P | [Penicillinase-producing Neisseria gonorrhoeae]. | 1976 Nov-Dec | Arch Belg Med Soc | pmid:829480 |
| Brunton WA et al. | Erythromycin-resistant campylobacters. | 1978 Dec 23-30 | Lancet | pmid:82888 |
| Malik A et al. | Congenital syphilis: a reappraisal. | 1993 | Indian Pediatr | pmid:8288353 |
| Boiron M et al. | [Antro-pyloro-bulbar contractibility in diabetics studied by cineradiography. Effect of erythromycin]. | 1993 | Gastroenterol. Clin. Biol. | pmid:8288079 |
| Teague AC and Parks SK | Bacillary angiomatosis in a patient with AIDS. | 1993 | Ann Pharmacother | pmid:8286814 |
| Donowitz GR and Earnhardt KI | Azithromycin inhibition of intracellular Legionella micdadei. | 1993 | Antimicrob. Agents Chemother. | pmid:8285604 |