erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Retropharyngeal Abscess D017703 2 associated lipids
Salpingitis D012488 2 associated lipids
Nasopharyngitis D009304 2 associated lipids
Dysarthria D004401 2 associated lipids
Factor X Deficiency D005171 2 associated lipids
Elephantiasis D004604 2 associated lipids
Mastoiditis D008417 2 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
Postgastrectomy Syndromes D011178 2 associated lipids
Ehrlichiosis D016873 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Tomomasa T et al. Gastrointestinal sounds and migrating motor complex in fasted humans. 1999 Am. J. Gastroenterol. pmid:10022632
Glupczynski Y and Burette A Failure of azythromycin to eradicate Campylobacter pylori from the stomach because of acquired resistance during treatment. 1990 Am. J. Gastroenterol. pmid:2153337
Chang AD et al. Bacillary angiomatosis associated with extensive esophageal polyposis: a new mucocutaneous manifestation of acquired immunodeficiency disease (AIDS). 1996 Am. J. Gastroenterol. pmid:8855753
DiBaise JK et al. Effects of low doses of erythromycin on the 13C Spirulina platensis gastric emptying breath test and electrogastrogram: a controlled study in healthy volunteers. 2001 Am. J. Gastroenterol. pmid:11467630
VIRANUVATTI V and BISESHURARIT P Clinical trial of erythromycin in amebic liver abscess. 1955 Am. J. Gastroenterol. pmid:13228406
Jones KL et al. The effect of erythromycin on gastric emptying is modified by physiological changes in the blood glucose concentration. 1999 Am. J. Gastroenterol. pmid:10445530
Fiorucci S et al. Effect of erythromycin on gastric and gallbladder emptying and gastrointestinal symptoms in scleroderma patients is maintained medium term. 1994 Am. J. Gastroenterol. pmid:8147358
Bachman BA et al. Erythromycin ethylsuccinate-induced cholestasis. 1982 Am. J. Gastroenterol. pmid:6979924
Resnick J et al. Delayed gastric emptying and postoperative ileus after nongastric abdominal surgery: part II. 1997 Am. J. Gastroenterol. pmid:9177505
Camilleri M The current role of erythromycin in the clinical management of gastric emptying disorders. 1993 Am. J. Gastroenterol. pmid:8424415
Ruffin WK Erythromycin: a postoperative jumpstart? 1994 Am. J. Gastroenterol. pmid:7909647
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Moussa F et al. Erythromycin eye ointment: effect on gastrointestinal motility. 2000 Am. J. Gastroenterol. pmid:10710093
Kalkay MN et al. Campylobacter-induced toxic megacolon. 1983 Am. J. Gastroenterol. pmid:6613968
Nolan CM et al. Campylobacter jejuni enteritis: efficacy of antimicrobial and antimotility drugs. 1983 Am. J. Gastroenterol. pmid:6624735
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Laine L and Jensen DM Management of patients with ulcer bleeding. 2012 Am. J. Gastroenterol. pmid:22310222
Tanaka M et al. Agranulocytosis induced by macrolide antibiotics. 1995 Am. J. Hematol. pmid:7847332
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Martínez-Maldonado M Postinfectious glomerulonephritis. 2000 Am. J. Kidney Dis. pmid:10636819
Mery JP and Kanfer A Alterations in pharmacokinetics and ototoxicity of erythromycin in renal failure. 1984 Am. J. Kidney Dis. pmid:6741942
Silang R et al. Prokinetic agents increase plasma albumin in hypoalbuminemic chronic dialysis patients with delayed gastric emptying. 2001 Am. J. Kidney Dis. pmid:11157368
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Curtis LH et al. Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients. 2003 Am. J. Med. pmid:12586234
Nattel S et al. Erythromycin-induced long QT syndrome: concordance with quinidine and underlying cellular electrophysiologic mechanism. 1990 Am. J. Med. pmid:2382671
Naot Y et al. IgM and IgG antibody response in two immunosuppressed patients with Legionnaires' disease. Evidence of reactivation of latent infection. 1982 Am. J. Med. pmid:6756135
Klein JO Emerging perspectives in management and prevention of infections of the respiratory tract in infants and children. 1985 Am. J. Med. pmid:4014286
Rudin JE et al. Failure of erythromycin in treatment of Legionella micdadei pneumonia. 1984 Am. J. Med. pmid:6607673
Diehl AM et al. Cholestatic hepatitis from erythromycin ethylsuccinate. Report of two cases. 1984 Am. J. Med. pmid:6609640
Parker RH et al. Erythromycin-resistant pneumococcal osteomyelitis. 1970 Am. J. Med. pmid:5415405
Sacristán JA and Soto J Erythromycin ototoxicity: methodology and conclusions. 1993 Am. J. Med. pmid:8430720
Wong KF et al. Psittacosis-associated hemophagocytic syndrome. 1991 Am. J. Med. pmid:1867249
Tablan OC and Reyes MP Chronic interstitial pulmonary fibrosis following Mycoplasma pneumoniae pneumonia. 1985 Am. J. Med. pmid:4025379
Vianna NJ and Hinman AR Rocky Mountain spotted fever on Long Island. Epidemiologic and clinical aspects. 1971 Am. J. Med. pmid:5129543
DAVIS DS and ROMANSKY MJ Successful treatment of gonococcic endocarditis with erythromycin; review of the literature. 1956 Am. J. Med. pmid:13354638
Swanson DJ et al. Erythromycin ototoxicity: prospective assessment with serum concentrations and audiograms in a study of patients with pneumonia. 1992 Am. J. Med. pmid:1731511
Petersdorf RG Antimicrobial prophylaxis of bacterial endocarditis. Prudent caution or bacterial overkill? 1978 Am. J. Med. pmid:99033
Moellering RC Introduction: revolutionary changes in the macrolide and azalide antibiotics. 1991 Am. J. Med. pmid:1656735
Neu HC Clinical microbiology of azithromycin. 1991 Am. J. Med. pmid:1656736
Stamm WE Azithromycin in the treatment of uncomplicated genital chlamydial infections. 1991 Am. J. Med. pmid:1656737
Nichols RL Use of prophylactic antibiotics in surgical practice. 1981 Am. J. Med. pmid:7011021
Wing EJ et al. Successful treatment of Legionella micdadei (Pittsburgh pneumonia agent) pneumonia with erythromycin. 1981 Am. J. Med. pmid:7304656
Bolton WK et al. Ventriculojugular shunt nephritis with Corynebacterium bovis. Successful therapy with antibiotics. 1975 Am. J. Med. pmid:1163549
Stocks JM et al. Ofloxacin in community-acquired lower respiratory infections. A comparison with amoxicillin or erythromycin. 1989 Am. J. Med. pmid:2690620
Dull JS et al. Successful treatment of gastroparesis with erythromycin in a patient with progressive systemic sclerosis. 1990 Am. J. Med. pmid:2220887
Bowler WA et al. Gastrointestinal side effects of intravenous erythromycin: incidence and reduction with prolonged infusion time and glycopyrrolate pretreatment. 1992 Am. J. Med. pmid:1546723
Bor DH and Himmelstein DU Endocarditis prophylaxis for patients with mitral valve prolapse. A quantitative analysis. 1984 Am. J. Med. pmid:6711576
Unertl KE et al. Ciprofloxacin in the treatment of legionellosis in critically ill patients including those cases unresponsive to erythromycin. 1989 Am. J. Med. pmid:2589356
Trimble GX Acute pancreatitis induced by erythromycin. 1989 Am. J. Med. pmid:2589410