erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Fail PA et al. | Comparative effects of quinacrine and erythromycin in adult female rats: a nonsurgical sterilization study. | 2000 | Fertil. Steril. | pmid:10685548 |
Yamano K et al. | Quantitative prediction of metabolic inhibition of midazolam by erythromycin, diltiazem, and verapamil in rats: implication of concentrative uptake of inhibitors into liver. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10688631 |
Noerr B | Erythromycin. | 1999 | Neonatal Netw | pmid:10690102 |
Thwaites RT and Frost JA | Drug resistance in Campylobacter jejuni, C coli, and C lari isolated from humans in north west England and Wales, 1997. | 1999 | J. Clin. Pathol. | pmid:10690169 |
Vardy SJ and Rose GE | Prevention of cellulitis after open lacrimal surgery: a prospective study of three methods. | 2000 | Ophthalmology | pmid:10690832 |
Hill BC et al. | A simplified method for testing Bordetella pertussis for resistance to erythromycin and other antimicrobial agents. | 2000 | J. Clin. Microbiol. | pmid:10699011 |
Timosca S et al. | [Bacteremia following tooth extractions]. | 1976 | Rev Stomatol Chir Maxillofac | pmid:1070098 |
Suri A et al. | Effects of CYP3A inhibition on the metabolism of cilostazol. | 1999 | Clin Pharmacokinet | pmid:10702888 |
Bernabéu JA et al. | Microbiological bioassay of erythromycin thiocyanate: optimisation and validation. | 1999 | J Pharm Biomed Anal | pmid:10703990 |
Brisaert M et al. | Investigation of the chemical stability of an erythromycin-tretinoin lotion by the use of an optimization system. | 2000 | Int J Pharm | pmid:10704802 |
Faoagali JL et al. | Sensitivity of 941 beta haemolytic streptococci to antibacterial drugs. | 1976 | N. Z. Med. J. | pmid:1070586 |
Karam B et al. | Ergotism precipitated by erythromycin: a rare case of vasospasm. | 2000 | Eur J Vasc Endovasc Surg | pmid:10706847 |
Sazykin IuO et al. | [Ketolides--erythromycin derivatives with activity against macrolide-resistant bacteria]. | 2000 | Antibiot. Khimioter. | pmid:10707799 |
MacLaren R et al. | Sequential single doses of cisapride, erythromycin, and metoclopramide in critically ill patients intolerant to enteral nutrition: a randomized, placebo-controlled, crossover study. | 2000 | Crit. Care Med. | pmid:10708180 |
Krecic-Shepard ME et al. | Gender-specific effects on verapamil pharmacokinetics and pharmacodynamics in humans. | 2000 | J Clin Pharmacol | pmid:10709150 |
Moussa F et al. | Erythromycin eye ointment: effect on gastrointestinal motility. | 2000 | Am. J. Gastroenterol. | pmid:10710093 |
Dewan NA et al. | Acute exacerbation of COPD: factors associated with poor treatment outcome. | 2000 | Chest | pmid:10712989 |
López de Blanc S et al. | Bacillary angiomatosis affecting the oral cavity. Report of two cases and review. | 2000 | J. Oral Pathol. Med. | pmid:10718405 |
Chepkwony HK et al. | Separation of erythromycin and related substances on base-deactivated reversed-phase silica gel columns. | 2000 | J Chromatogr A | pmid:10722081 |
Portillo A et al. | Macrolide resistance genes in Enterococcus spp. | 2000 | Antimicrob. Agents Chemother. | pmid:10722498 |
Brophy DF et al. | Pharmacokinetic interaction between amprenavir and clarithromycin in healthy male volunteers. | 2000 | Antimicrob. Agents Chemother. | pmid:10722500 |
Ono T et al. | Susceptibilities of oral and nasal isolates of Streptococcus mitis and Streptococcus oralis to macrolides and PCR detection of resistance genes. | 2000 | Antimicrob. Agents Chemother. | pmid:10722517 |
Strigl S et al. | In vitro activity of ABT 773, a new ketolide antibiotic, against Chlamydia pneumoniae. | 2000 | Antimicrob. Agents Chemother. | pmid:10722526 |
Gracey HE et al. | Preparation and in vitro antibacterial activity of 6-O-methylerythromycin D. | 1999 | J. Antibiot. | pmid:10726932 |
Smith AJ et al. | Prokinetic effect of erythromycin after colorectal surgery: randomized, placebo-controlled, double-blind study. | 2000 | Dis. Colon Rectum | pmid:10733114 |
Karchmer AW et al. | Single-antibiotic therapy for streptococcal endocarditis. | 1979 | JAMA | pmid:107335 |
Potts JM et al. | Association of chronic urinary symptoms in women and Ureaplasma urealyticum. | 2000 | Urology | pmid:10736488 |
Dubini F et al. | [Research on erythromycin and spiramycin in saliva]. | 1976 | Dent Cadmos | pmid:1073735 |
Or YS et al. | Design, synthesis, and antimicrobial activity of 6-O-substituted ketolides active against resistant respiratory tract pathogens. | 2000 | J. Med. Chem. | pmid:10737737 |
Orrett FA | Methicillin resistance among Trinidadian isolates of community and hospital strains of Staphylococcus aureus and their patterns of resistance to non-beta-lactam antibiotics. | 1999 | Jpn. J. Infect. Dis. | pmid:10738361 |
Erythromycin use linked to pyloric stenosis. | 2000 | Am J Nurs | pmid:10738394 | |
Nielsen K et al. | Susceptibility of Legionella species to five antibiotics and development of resistance by exposure to erythromycin, ciprofloxacin, and rifampicin. | 2000 | Diagn. Microbiol. Infect. Dis. | pmid:10744366 |
Simango C and Mvududu F | Penicillin resistant Streptococcus pneumoniae isolates in Harare, Zimbabwe. | 1999 | Cent Afr J Med | pmid:10746390 |
Martinez JA et al. | Diffuse panbronchiolitis in Latin America. | 2000 | Am. J. Med. Sci. | pmid:10746829 |
Davies TA et al. | Antipneumococcal activity of telithromycin by agar dilution, microdilution, E test, and disk diffusion methodologies. | 2000 | J. Clin. Microbiol. | pmid:10747123 |
Luna VA et al. | A novel multiresistant Streptococcus pneumoniae serogroup 19 clone from Washington State identified by pulsed-field gel electrophoresis and restriction fragment length patterns. | 2000 | J. Clin. Microbiol. | pmid:10747146 |
Furneri PM et al. | Genetic basis of natural resistance to erythromycin in Mycoplasma hominis. | 2000 | J. Antimicrob. Chemother. | pmid:10747837 |
Faure C et al. | Effect of meal and intravenous erythromycin on manometric and electrogastrographic measurements of gastric motor and electrical activity. | 2000 | Dig. Dis. Sci. | pmid:10749328 |
Hoppe JE | Neonatal pertussis. | 2000 | Pediatr. Infect. Dis. J. | pmid:10749468 |
Zhao DM et al. | Effect of erythromycin on ATP-induced intracellular calcium response in A549 cells. | 2000 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:10749750 |
Clanton LJ and Bender J | Refractory spinal cord injury induced gastroparesis: resolution with erythromycin lactobionate, a case report. | 1999 | J Spinal Cord Med | pmid:10751126 |
Murata T et al. | [Serum concentration of erythromycin suppositories and clinical use in oral surgery (author's transl)]. | 1975 | Nihon Koku Geka Gakkai Zasshi | pmid:1075289 |
Solensky R et al. | Clinical approach to penicillin-allergic patients: a survey. | 2000 | Ann. Allergy Asthma Immunol. | pmid:10752918 |
Petrakis IE et al. | Induced-hyperglycemia attenuates erythromycin-induced acceleration of hypertonic liquid-phase gastric emptying in type-I diabetic patients. | 1999 | Dig Dis | pmid:10754365 |
Brenciaglia MI et al. | Helicobacter pylori: cultivability and antibiotic susceptibility of coccoid forms. | 2000 | Int. J. Antimicrob. Agents | pmid:10755237 |
Bellaïche G et al. | [Non-hemorrhagic and erythematous colitis associated with Klebsiella oxytoca after treatment with erythromycin]. | 2000 | Gastroenterol. Clin. Biol. | pmid:10755860 |
Stamm LV and Bergen HL | A point mutation associated with bacterial macrolide resistance is present in both 23S rRNA genes of an erythromycin-resistant Treponema pallidum clinical isolate. | 2000 | Antimicrob. Agents Chemother. | pmid:10755994 |
Bassetti M et al. | Erythromycin resistance in Streptococcus pyogenes in Italy. | 2000 Mar-Apr | Emerging Infect. Dis. | pmid:10756153 |
Majima Y et al. | [Study on a rat tracheal mucus producing model]. | 2000 | Jpn J Antibiot | pmid:10756441 |
Nakaya Y et al. | [Suppressive action of erythromycin on cultured tracheal epithelial cell chloride channel activated by interferon-gamma]. | 2000 | Jpn J Antibiot | pmid:10756442 |