erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Huang M et al. | Single nucleotide polymorphism of CYP3A4 intron 2 and its influence on CYP3A4 mRNA expression and liver enzymatic activity in human liver. | 2015 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:26223917 |
Schneider SC et al. | Antibiotic Susceptibility and Sequence Type Distribution of Ureaplasma Species Isolated from Genital Samples in Switzerland. | 2015 | Antimicrob. Agents Chemother. | pmid:26195516 |
Takagi M et al. | Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. | 2015 | Drug Metab. Pharmacokinet. | pmid:26195223 |
Aydin S et al. | Development of antibiotic resistance genes in microbial communities during long-term operation of anaerobic reactors in the treatment of pharmaceutical wastewater. | 2015 | Water Res. | pmid:26188597 |
Fayed B et al. | Multiplexed integrating plasmids for engineering of the erythromycin gene cluster for expression in Streptomyces spp. and combinatorial biosynthesis. | 2015 | Appl. Environ. Microbiol. | pmid:26431970 |
Reveiz L and Cardona AF | Antibiotics for acute laryngitis in adults. | 2015 | Cochrane Database Syst Rev | pmid:26002823 |
Pesola AK et al. | Clindamycin resistant emm33 Streptococcus pyogenes emerged among invasive infections in Helsinki metropolitan area, Finland, 2012 to 2013. | 2015 | Euro Surveill. | pmid:25990232 |
Sun XJ et al. | Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-δ/Akt pathway and increasing GR expression. | 2015 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:25957293 |
Ou H et al. | Selective removal of erythromycin by magnetic imprinted polymers synthesized from chitosan-stabilized Pickering emulsion. | 2015 | J. Hazard. Mater. | pmid:25704432 |
Ikebe T et al. | Increased prevalence of group A streptococcus isolates in streptococcal toxic shock syndrome cases in Japan from 2010 to 2012. | 2015 | Epidemiol. Infect. | pmid:25703404 |
Li Y et al. | Where macrolide resistance is prevalent. | 2015 | APMIS | pmid:25703275 |
Choi JH et al. | Distribution of emm types among group A Streptococcus isolates from children in Korea. | 2015 | Diagn. Microbiol. Infect. Dis. | pmid:25700867 |
Luo H et al. | Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. | 2015 | Avian Pathol. | pmid:25690020 |
Harmer CJ et al. | A type 2 A/C2 plasmid carrying the aacC4 apramycin resistance gene and the erm(42) erythromycin resistance gene recovered from two Salmonella enterica serovars. | 2015 | J. Antimicrob. Chemother. | pmid:25468903 |
Wan J et al. | Effect of erythromycin exposure on the growth, antioxidant system and photosynthesis of Microcystis flos-aquae. | 2015 | J. Hazard. Mater. | pmid:25464321 |
Zhou Z et al. | Macrolide-resistant Mycoplasma pneumoniae in adults in Zhejiang, China. | 2015 | Antimicrob. Agents Chemother. | pmid:25451048 |
Hur J et al. | Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. | 2015 | Chem. Res. Toxicol. | pmid:25811541 |
Llorca M et al. | Identification of new transformation products during enzymatic treatment of tetracycline and erythromycin antibiotics at laboratory scale by an on-line turbulent flow liquid-chromatography coupled to a high resolution mass spectrometer LTQ-Orbitrap. | 2015 | Chemosphere | pmid:24972175 |
Yamaguchi M et al. | Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche. | 2015 | Cell Rep | pmid:26440893 |
Chazan B et al. | Susceptibility of Group A Streptococcus to Antimicrobial Agents in Northern Israel: A Surveillance Study. | 2015 | Microb. Drug Resist. | pmid:26430943 |
Hoffmann K et al. | Prevalence and resistance patterns of commensal S. aureus in community-dwelling GP patients and socio-demographic associations. A cross-sectional study in the framework of the APRES-project in Austria. | 2015 | BMC Infect. Dis. | pmid:25981559 |
Wang Z et al. | Direct Detection of Erythromycin-Resistant Bordetella pertussis in Clinical Specimens by PCR. | 2015 | J. Clin. Microbiol. | pmid:26224847 |
Olivieri R et al. | Evolution of macrolide resistance in Streptococcus pyogenes over 14 years in an area of central Italy. | 2015 | J. Med. Microbiol. | pmid:26224594 |
Mazumdar G and Shome K | Stevens-Johnson syndrome following use of metronidazole in a dental patient. | 2014 Jan-Feb | Indian J Pharmacol | pmid:24550598 |
Wang J et al. | Association of osteopontin polymorphisms with nasopharyngeal carcinoma risk. | 2014 | Hum. Immunol. | pmid:24120738 |
Cetecioglu Z | Aerobic inhibition assessment for anaerobic treatment effluent of antibiotic production wastewater. | 2014 | Environ Sci Pollut Res Int | pmid:24146324 |
Gustafsson F et al. | A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans. | 2014 | Toxicol. Sci. | pmid:24085192 |
Källén B and Danielsson BR | Fetal safety of erythromycin. An update of Swedish data. | 2014 | Eur. J. Clin. Pharmacol. | pmid:24352632 |
ŽemliÄková H et al. | [Resistance monitoring working group: resistance to erythromycin, ciprofloxacin, and tetracycline in human isolates of Campylobacter spp. in the Czech Republic tested by the EUCAST standard method]. | 2014 | Epidemiol Mikrobiol Imunol | pmid:25412481 |
Arêas GP et al. | Antimicrobial susceptibility patterns, emm type distribution and genetic diversity of Streptococcus pyogenes recovered in Brazil. | 2014 | Mem. Inst. Oswaldo Cruz | pmid:25410998 |
Wang J et al. | [Drug susceptibility and homologous analysis on Corynebacterium striatum strains isolated from inpatients]. | 2014 | Zhonghua Yi Xue Za Zhi | pmid:25410920 |
Labbeiki G et al. | Enhanced oxygen transfer rate and bioprocess yield by using magnetite nanoparticles in fermentation media of erythromycin. | 2014 | Daru | pmid:25223458 |
Bharucha AE et al. | A prospective randomized controlled study of erythromycin on gastric and small intestinal distention: implications for MR enterography. | 2014 | Eur J Radiol | pmid:25217123 |
Johnson SR et al. | In Vitro selection of Neisseria gonorrhoeae mutants with elevated MIC values and increased resistance to cephalosporins. | 2014 | Antimicrob. Agents Chemother. | pmid:25199775 |
Kara M et al. | Expression changes of antioxidant, apoptotic, anti-apoptotic genes and miR-15b-34a-21-98 in over tissue by using erythromycin, quinacrine and tetracycline in non-surgical sterilization. | 2014 | Mol. Biol. Rep. | pmid:25195052 |
Mayanskiy N et al. | Serotypes and antibiotic resistance of non-invasive Streptococcus pneumoniae circulating in pediatric hospitals in Moscow, Russia. | 2014 | Int. J. Infect. Dis. | pmid:24462930 |
Moore KT et al. | An open-label study to estimate the effect of steady-state erythromycin on the pharmacokinetics, pharmacodynamics, and safety of a single dose of rivaroxaban in subjects with renal impairment and normal renal function. | 2014 | J Clin Pharmacol | pmid:24964176 |
Montilla A et al. | Genetic environment of the lnu(B) gene in a Streptococcus agalactiae clinical isolate. | 2014 | Antimicrob. Agents Chemother. | pmid:24957835 |
Komiya K et al. | Long-term, low-dose erythromycin monotherapy for Mycobacterium avium complex lung disease: a propensity score analysis. | 2014 | Int. J. Antimicrob. Agents | pmid:24948577 |
Dutra VG et al. | Streptococcus agalactiae in Brazil: serotype distribution, virulence determinants and antimicrobial susceptibility. | 2014 | BMC Infect. Dis. | pmid:24919844 |
Arana DM et al. | First clinical isolate in Europe of clindamycin-resistant group B Streptococcus mediated by the lnu(B) gene. | 2014 | Rev Esp Quimioter | pmid:24940891 |
Crumb WJ | Allosteric effects of erythromycin pretreatment on thioridazine block of hERG potassium channels. | 2014 | Br. J. Pharmacol. | pmid:24417241 |
Luan R et al. | [Erythromycin for improving enteral nutrition tolerance in adult critical patients: a systematic review and meta-analysis]. | 2014 | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | pmid:24912643 |
Heriot WJ et al. | Ocular involvement in a patient with Legionella longbeachae 1 infection. | 2014 | Clin. Experiment. Ophthalmol. | pmid:24650007 |
Calvert H et al. | Effect of erlotinib on CYP3A activity, evaluated in vitro and by dual probes in patients with cancer. | 2014 | Anticancer Drugs | pmid:24637575 |
Janoir C et al. | Clonal expansion of the macrolide resistant ST386 within pneumococcal serotype 6C in France. | 2014 | PLoS ONE | pmid:24603763 |
Melnik BC | The P450 system and mTORC1 signalling in acne. | 2014 | Exp. Dermatol. | pmid:24588627 |
Xiao C et al. | Effect of magnesium sulfate and nifedipine on the risk of developing pulmonary edema in preterm births. | 2014 | J Perinat Med | pmid:24566358 |
Csikó G et al. | Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens. | 2014 | J. Vet. Pharmacol. Ther. | pmid:24628435 |
Aydin S et al. | Performance of anaerobic sequencing batch reactor in the treatment of pharmaceutical wastewater containing erythromycin and sulfamethoxazole mixture. | 2014 | Water Sci. Technol. | pmid:25429450 |