| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vanden Boom TJ | Recent developments in the molecular genetics of the erythromycin-producing organism Saccharopolyspora erythraea. | 2000 | Adv. Appl. Microbiol. | pmid:12876795 |
| Vining LC | Antibiotic tolerance in producer organisms. | 1979 | Adv. Appl. Microbiol. | pmid:94753 |
| Lechevalier HA | Production of the same antibiotics by members of different genera of microorganisms. | 1975 | Adv. Appl. Microbiol. | pmid:52998 |
| Waksman SA | Successes and failures in the search for antibiotics. | 1969 | Adv. Appl. Microbiol. | pmid:4195044 |
| Williams GJ and Thorson JS | Natural product glycosyltransferases: properties and applications. | 2009 | Adv. Enzymol. Relat. Areas Mol. Biol. | pmid:18990828 |
| Mortensen JE and McDowell T | Streptococcus pyogenes: resistant, tolerant, neither or both? | 1995 | Adv. Exp. Med. Biol. | pmid:8718606 |
| Ferraro AL et al. | The antimicrobial susceptibility of Streptococcus pyogenes isolates from the Philadelphia area. | 1995 | Adv. Exp. Med. Biol. | pmid:8718607 |
| Garber NC et al. | Regulation of lectin production by the human pathogens Pseudomonas aeruginosa and Chromobacterium violaceum: effects of choline, trehalose, and ethanol. | 2011 | Adv. Exp. Med. Biol. | pmid:21618111 |
| Siekmeier R et al. | Inhalation of macrolides: a novel approach to treatment of pulmonary infections. | 2015 | Adv. Exp. Med. Biol. | pmid:25252902 |
| Klein TW et al. | Legionella pneumophila infection and cytokine production. | 1992 | Adv. Exp. Med. Biol. | pmid:1414610 |
| Yang YH et al. | Opacity factor inhibition test for typing group A beta-haemolytic streptococcus strains and antibiotic susceptibility. | 1997 | Adv. Exp. Med. Biol. | pmid:9331595 |
| Jasir A and Schalén C | Erythromycin resistance phenotypes in Swedish clinical isolates of group A streptococci. | 1997 | Adv. Exp. Med. Biol. | pmid:9331689 |
| Savoia D et al. | Group A streptococci. Erythromycin resistance and penicillin tolerance. | 1997 | Adv. Exp. Med. Biol. | pmid:9331690 |
| Vicarini H et al. | Analysis of regulatory region of ermAM genes in streptococci and enterococci highly resistant to macrolides and lincosamides. | 1997 | Adv. Exp. Med. Biol. | pmid:9331702 |
| Dansette PM et al. | Drug interactions with macrolide antibiotics: specificity of pseudo-suicide inhibition and induction of cytochrome P-450. | 1986 | Adv. Exp. Med. Biol. | pmid:3490132 |
| Yayan J and Rasche K | Growing Antibiotic Resistance in Fatal Cases of Staphylococcal Pneumonia in the Elderly. | Adv. Exp. Med. Biol. | pmid:26747068 | |
| Lartey PA et al. | New developments in macrolides: structures and antibacterial and prokinetic activities. | 1994 | Adv. Pharmacol. | pmid:8080820 |
| Garrett RA and Wittmann HG | Structure of bacterial ribosomes. | 1973 | Adv. Protein Chem. | pmid:4589667 |
| Dully FE | Streptococcal epidemic in an aircraft carrier. | 1973 | Aerosp Med | pmid:4201795 |
| Ogwal S and Xide TU | Bioavailability and stability of erythromycin delayed release tablets. | 2001 | Afr Health Sci | pmid:12789122 |