erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kozak PP et al. | Administration of erythromycin to patients on theophylline. | 1977 | J. Allergy Clin. Immunol. | pmid:874213 |
Ohba M et al. | Effect of clarithromycin on the bioavailability of cyclosporin in rats. | 1996 | Biol. Pharm. Bull. | pmid:8741585 |
Hoppe JE | Update of epidemiology, diagnosis, and treatment of pertussis. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8740851 |
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Fujii T et al. | Inhibitory effect of erythromycin on interleukin 8 production by 1 alpha,25-dihydroxyvitamin D3-stimulated THP-1 cells. | 1996 | Antimicrob. Agents Chemother. | pmid:8726037 |
Champney WS and Burdine R | 50S ribosomal subunit synthesis and translation are equivalent targets for erythromycin inhibition in Staphylococcus aureus. | 1996 | Antimicrob. Agents Chemother. | pmid:8723490 |
van Hoogdalem EJ et al. | Evaluation of the effect of zinc acetate on the stratum corneum penetration kinetics of erythromycin in healthy male volunteers. | 1996 | Skin Pharmacol. | pmid:8722604 |
Hall G et al. | Elimination of bacteraemia after dental extraction: comparison of erythromycin and clindamycin for prophylaxis of infective endocarditis. | 1996 | J. Antimicrob. Chemother. | pmid:8722544 |
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Tateishi T et al. | Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation. | 1996 | Anesth. Analg. | pmid:8712396 |
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Vanderhoof JA et al. | Treatment of cyclic vomiting in childhood with erythromycin. | 1995 | J. Pediatr. Gastroenterol. Nutr. | pmid:8708873 |
Nichterlein T et al. | RP 59500, a streptogramin derivative, is effective in murine listeriosis. | 1996 | J Chemother | pmid:8708741 |
Arranz-Caso JA et al. | Prolonged colonic pseudo-obstruction (Ogilvie syndrome) in an older woman resolved with conservative treatment. | 1996 | J Am Geriatr Soc | pmid:8708296 |
Paz HL et al. | Motility agents for the placement of weighted and unweighted feeding tubes in critically ill patients. | 1996 | Intensive Care Med | pmid:8708166 |
Zanetti S et al. | In-vitro activity of 3-azinomethyl-rifamycin (SPA-S-565) against Chlamydia trachomatis. | 1996 | J. Antimicrob. Chemother. | pmid:8707747 |
Higgins SP | Chlamydial infection in women. | 1996 | Br J Gen Pract | pmid:8703535 |
RamÃrez RamÃrez CR et al. | Bacillary angiomatosis: microbiology, histopathology, clinical presentation, diagnosis and management. | 1995 Jul-Sep | Bol Asoc Med P R | pmid:8703269 |
McBride MJ and Baker SA | Development of techniques to genetically manipulate members of the genera Cytophaga, Flavobacterium, Flexibacter, and Sporocytophaga. | 1996 | Appl. Environ. Microbiol. | pmid:8702294 |
Wasteson Y et al. | Characterization of tetracycline and erythromycin resistance in Actinobacillus pleuropneumoniae. | 1996 | Vet. Microbiol. | pmid:8701576 |
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Hall JE and Harmer M | Erythromycin as a prokinetic agent in children. | 1996 | Anaesthesia | pmid:8694177 |
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Bailey DG et al. | Erythromycin-felodipine interaction: magnitude, mechanism, and comparison with grapefruit juice. | 1996 | Clin. Pharmacol. Ther. | pmid:8689808 |
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Burgin S and Spencer DC | Bacillary angiomatosis--another South African case. | 1996 | S. Afr. Med. J. | pmid:8685799 |
Edelman K et al. | Detection of Bordetella pertussis by polymerase chain reaction and culture in the nasopharynx of erythromycin-treated infants with pertussis. | 1996 | Pediatr. Infect. Dis. J. | pmid:8684877 |
El-Chaar GM et al. | Randomized, double blind comparison of brand and generic antibiotic suspensions: II. A study of taste and compliance in children. | 1996 | Pediatr. Infect. Dis. J. | pmid:8684871 |
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Griesgraber G et al. | 3-Keto-11,12-carbazate derivatives of 6-O-methylerythromycin A synthesis and in vitro activity. | 1996 | J. Antibiot. | pmid:8682724 |
Davies JS and Penfold JB | Campylobacter urinary infection. | 1979 | Lancet | pmid:86820 |
Backström M and Kuusela AL | [Unilateral pulmonary edema in an infant]. | 1995 | Duodecim | pmid:8681845 |
Sturm A et al. | [Treatment of radiotherapy-induced gastroparesis with erythromycin]. | 1996 | Dtsch. Med. Wochenschr. | pmid:8681733 |
Coulter WA et al. | Dental anxiety and the absorption of orally administered erythromycin stearate. | 1995 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod | pmid:8680971 |
Rowbury RJ et al. | Sensitization to acid induced by sodium ions in Escherichia coli: dependence of (p)ppGpp and cAMP and suppression of the relA-associated defect by mutations in envZ. | 1996 | Microbios | pmid:8676748 |
Zhou D and Apicella MA | Plasmids with erythromycin resistance and catechol 2,3-dioxygenase- or beta-galactosidase-encoding gene cassettes for use in Neisseria spp. | 1996 | Gene | pmid:8675023 |
Surrenti E et al. | Antral axial forces postprandially and after erythromycin in organic and functional dysmotilities. | 1996 | Dig. Dis. Sci. | pmid:8674390 |
Nikulin KG | [Treatment of acute pneumonia at different stages of the disease]. | 1977 | Ter. Arkh. | pmid:867244 |
McMeekin TO and Moschella SL | Iatrogenic complications of dermatologic therapy. Primum non nocere. | 1979 | Med. Clin. North Am. | pmid:86664 |
Lode H et al. | Treatment of community-acquired pneumonia: a randomized comparison of sparfloxacin, amoxycillin-clavulanic acid and erythromycin. | 1995 | Eur. Respir. J. | pmid:8666093 |
Johnson AP et al. | Prevalence of antibiotic resistance and serotypes in pneumococci in England and Wales: results of observational surveys in 1990 and 1995. | 1996 | BMJ | pmid:8664623 |
Aleksandrova AE and Vinogradova TI | [Immunotropic activity of antimicrobial agents used in tuberculosis]. | 1996 | Probl Tuberk | pmid:8657696 |
King DE et al. | Effectiveness of erythromycin in the treatment of acute bronchitis. | 1996 | J Fam Pract | pmid:8656171 |
Packman AM et al. | Treatment of acne vulgaris: combination of 3% erythromycin and 5% benzoyl peroxide in a gel compared to clindamycin phosphate lotion. | 1996 | Int. J. Dermatol. | pmid:8655242 |
Kligman AM | The treatment of acne. Part III: antibacterials. | 1995 | Cutis | pmid:8654122 |
Mashkilleyson AL et al. | Treatment of syphilis with azithromycin. | 1996 | Int J STD AIDS | pmid:8652720 |
Pieper R et al. | Erythromycin biosynthesis: kinetic studies on a fully active modular polyketide synthase using natural and unnatural substrates. | 1996 | Biochemistry | pmid:8652546 |
Vickery CL et al. | Bacillary angiomatosis presenting as a nasal mass with epistaxis. | 1996 | Otolaryngol Head Neck Surg | pmid:8649879 |
Dam M et al. | Mutations in domain II of 23 S rRNA facilitate translation of a 23 S rRNA-encoded pentapeptide conferring erythromycin resistance. | 1996 | J. Mol. Biol. | pmid:8648637 |
Yasui N et al. | A kinetic and dynamic study of oral alprazolam with and without erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in alprazolam metabolism. | 1996 | Clin. Pharmacol. Ther. | pmid:8646822 |
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Fang CC et al. | Erythromycin-induced acute pancreatitis. | 1996 | J. Toxicol. Clin. Toxicol. | pmid:8632521 |
Cohen LG et al. | Erythromycin-induced clozapine toxic reaction. | 1996 | Arch. Intern. Med. | pmid:8629881 |
Huang XM et al. | Base decomposition of erythromycin A methoxime. | 1996 | J. Antibiot. | pmid:8626251 |
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Noguchi N et al. | Nucleotide sequence and characterization of erythromycin resistance determinant that encodes macrolide 2'-phosphotransferase I in Escherichia coli. | 1995 | Antimicrob. Agents Chemother. | pmid:8619599 |
Hsueh PR et al. | Decreased activity of erythromycin against Streptococcus pyogenes in Taiwan. | 1995 | Antimicrob. Agents Chemother. | pmid:8619575 |
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Thompson D and Oster G | Use of terfenadine and contraindicated drugs. | 1996 | JAMA | pmid:8614120 |
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Feierman DE | Identification of cytochrome P450 3A1/2 as the major P450 isoform responsible for the metabolism of fentanyl by rat liver microsomes. | 1996 | Anesth. Analg. | pmid:8610902 |
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The choice of antibacterial drugs. | 1996 | Med Lett Drugs Ther | pmid:8598824 | |
Schachter J and Dawson CR | Is trachoma an ocular component of a more generalised chlamydial infection? | 1979 | Lancet | pmid:85939 |
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Lucier TS et al. | Transition mutations in the 23S rRNA of erythromycin-resistant isolates of Mycoplasma pneumoniae. | 1995 | Antimicrob. Agents Chemother. | pmid:8593017 |
Bental T et al. | Chronic Q fever of pregnancy presenting as Coxiella burnetii placentitis: successful outcome following therapy with erythromycin and rifampin. | 1995 | Clin. Infect. Dis. | pmid:8589167 |
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Hamzehpour MM et al. | OprK and OprM define two genetically distinct multidrug efflux systems in Pseudomonas aeruginosa. | 1995 | Antimicrob. Agents Chemother. | pmid:8585714 |
De Serres G et al. | Field effectiveness of erythromycin prophylaxis to prevent pertussis within families. | 1995 | Pediatr. Infect. Dis. J. | pmid:8584364 |
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Minocha A et al. | Erythromycin shortens orocaecal transit time in diabetic male subjects: a double-blind placebo-controlled study. | 1995 | Aliment. Pharmacol. Ther. | pmid:8580273 |
Slomiany BL et al. | Sucralfate affects the susceptibility of Helicobacter pylori to antimicrobial agents. | 1995 | Scand. J. Gastroenterol. Suppl. | pmid:8578215 |
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