erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ishibashi K et al. | Short-term intravenous antimicrobial prophylaxis for elective rectal cancer surgery: results of a prospective randomized non-inferiority trial. | 2014 | Surg. Today | pmid:23989910 |
Wang J et al. | Association of osteopontin polymorphisms with nasopharyngeal carcinoma risk. | 2014 | Hum. Immunol. | pmid:24120738 |
Silva CM et al. | Population dynamics and antimicrobial susceptibility of Aeromonas spp. along a salinity gradient in an urban estuary in Northeastern Brazil. | 2014 | Mar. Pollut. Bull. | pmid:25455376 |
Badri T et al. | [Erythrasma: study of 16 cases]. | 2014 | Tunis Med | pmid:25224418 |
Dörries K et al. | Impact of antibiotics with various target sites on the metabolome of Staphylococcus aureus. | 2014 | Antimicrob. Agents Chemother. | pmid:25224006 |
Labbeiki G et al. | Enhanced oxygen transfer rate and bioprocess yield by using magnetite nanoparticles in fermentation media of erythromycin. | 2014 | Daru | pmid:25223458 |
Bharucha AE et al. | A prospective randomized controlled study of erythromycin on gastric and small intestinal distention: implications for MR enterography. | 2014 | Eur J Radiol | pmid:25217123 |
Mott M et al. | Susceptibility profiles and correlation with pneumococcal serotypes soon after implementation of the 10-valent pneumococcal conjugate vaccine in Brazil. | 2014 | Int. J. Infect. Dis. | pmid:24389158 |
Mayanskiy N et al. | Serotypes and antibiotic resistance of non-invasive Streptococcus pneumoniae circulating in pediatric hospitals in Moscow, Russia. | 2014 | Int. J. Infect. Dis. | pmid:24462930 |
Ramos V et al. | [Mobile genetic elements associated with erythromycin-resistant isolates of Streptococcus pneumoniae in Colombia]. | 2014 | Biomedica | pmid:24968052 |
Moore KT et al. | An open-label study to estimate the effect of steady-state erythromycin on the pharmacokinetics, pharmacodynamics, and safety of a single dose of rivaroxaban in subjects with renal impairment and normal renal function. | 2014 | J Clin Pharmacol | pmid:24964176 |
Montilla A et al. | Genetic environment of the lnu(B) gene in a Streptococcus agalactiae clinical isolate. | 2014 | Antimicrob. Agents Chemother. | pmid:24957835 |
Wang D et al. | Structural and environmental features of novel mdfA variant and mdfA genes in recombinant regions of Escherichia coli. | 2014 | Microb. Drug Resist. | pmid:24684286 |
Arenz S et al. | Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide. | 2014 | Nat Commun | pmid:24662426 |
Fernández Fuentes MA et al. | Synergistic activity of biocides and antibiotics on resistant bacteria from organically produced foods. | 2014 | Microb. Drug Resist. | pmid:24660956 |
Heriot WJ et al. | Ocular involvement in a patient with Legionella longbeachae 1 infection. | 2014 | Clin. Experiment. Ophthalmol. | pmid:24650007 |
Calvert H et al. | Effect of erlotinib on CYP3A activity, evaluated in vitro and by dual probes in patients with cancer. | 2014 | Anticancer Drugs | pmid:24637575 |
Kim S and Muthusamy VR | Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045591 |
Theivanayagam S et al. | Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045593 |
Manchia M et al. | Repeated erythromycin/codeine-induced psychotic mania. | 2013 Sep-Oct | Clin Neuropharmacol | pmid:24045612 |
De Alwis HG et al. | Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. | 2013 Nov-Dec | J AOAC Int | pmid:24645499 |
Zou X et al. | Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. | 2013 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:23795479 |
Jiang M et al. | Improved heterologous erythromycin A production through expression plasmid re-design. | 2013 Jul-Aug | Biotechnol. Prog. | pmid:23804312 |
Lynch M et al. | Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. | 2013 Jan-Feb | Pediatr Dermatol | pmid:23316718 |
Litvinchuk AV et al. | Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. | 2013 Apr-May | Eur. J. Cell Biol. | pmid:23523087 |
Nie XP et al. | Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole exposure to the antioxidant system in Pseudokirchneriella subcapitata. | 2013 | Environ. Pollut. | pmid:22982550 |
Parrott N et al. | An unusual cause of persistent postpartum vaginal discharge. | 2013 | Int J STD AIDS | pmid:23970614 |
Pelchovich G et al. | The contribution of common rpsL mutations in Escherichia coli to sensitivity to ribosome targeting antibiotics. | 2013 | Int. J. Med. Microbiol. | pmid:23972615 |
Ishihara K et al. | Distribution of antimicrobial-resistant lactic acid bacteria in natural cheese in Japan. | 2013 | Microbiol. Immunol. | pmid:23930694 |
Hirano E et al. | Erythromycin treatment suppresses myocardial injury in autoimmune myocarditis in rats via suppression of superoxide production. | 2013 | Int. J. Cardiol. | pmid:22727964 |
Wang HB et al. | Molecular epidemiological analysis of group A Streptococci isolated from children in Chaoyang District of Beijing, 2011: emm types, virulence factor genes and erythromycin resistant genes. | 2013 | Biomed. Environ. Sci. | pmid:24099615 |
Wang X et al. | Mesoporous titanium zirconium oxide nanospheres with potential for drug delivery applications. | 2013 | ACS Appl Mater Interfaces | pmid:24150740 |
Ziesenitz VC et al. | Cytochrome P450-3A phenotyping using midazolam is not altered by OATP1B1 polymorphisms. | 2013 | Clin. Pharmacol. Ther. | pmid:23549145 |
Kirm B et al. | SACE_5599, a putative regulatory protein, is involved in morphological differentiation and erythromycin production in Saccharopolyspora erythraea. | 2013 | Microb. Cell Fact. | pmid:24341557 |
Olender A et al. | The cause of Actinomyces canalictulis--a case study. | 2013 | Ann Agric Environ Med | pmid:24364446 |
Prabu D and Menon T | Genotyping of erythromycin resistant group C & G streptococci isolated in Chennai, south India. | 2013 | Indian J. Med. Res. | pmid:23481067 |
Zhang Y et al. | Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23481648 |
Koulaouzidis A et al. | Do prokinetics influence the completion rate in small-bowel capsule endoscopy? A systematic review and meta-analysis. | 2013 | Curr Med Res Opin | pmid:23790243 |
Sundermann U et al. | Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase. | 2013 | ACS Chem. Biol. | pmid:23181268 |
Everson GT et al. | Functional elements associated with hepatic regeneration in living donors after right hepatic lobectomy. | 2013 | Liver Transpl. | pmid:23239552 |
Kelmer G et al. | Evaluation of regional limb perfusion with erythromycin using the saphenous, cephalic, or palmar digital veins in standing horses. | 2013 | J. Vet. Pharmacol. Ther. | pmid:23240633 |
Oplinger RW and Wagner EJ | Control of Flavobacterium psychrophilum: tests of erythromycin, streptomycin, osmotic and thermal shocks, and rapid pH change. | 2013 | J. Aquat. Anim. Health | pmid:23241009 |
Li N et al. | Effect of corilagin on membrane permeability of Escherichia coli, Staphylococcus aureus and Candida albicans. | 2013 | Phytother Res | pmid:23192753 |
Boutouyrie-Dumont B | An aide memoire for model-based drug development--a new key for the interpretation of the erythromycin breath test--therapeutic index as a biomarker for smart drug development. | 2013 | Biomark Med | pmid:23387489 |
Liang JH et al. | Synthesis and antibacterial activity of 9-oxime ether non-ketolides, and novel binding mode of alkylides with bacterial rRNA. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23375796 |
Drago L et al. | Phenotypic and genotypic antibiotic resistance in some probiotics proposed for medical use. | 2013 | Int. J. Antimicrob. Agents | pmid:23313535 |
Serisier DJ et al. | Effect of long-term, low-dose erythromycin on pulmonary exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trial. | 2013 | JAMA | pmid:23532242 |
Elborn JS and Tunney MM | Macrolides and bronchiectasis: clinical benefit with a resistance price. | 2013 | JAMA | pmid:23532247 |
Chan BC et al. | Synergistic effects of diosmetin with erythromycin against ABC transporter over-expressed methicillin-resistant Staphylococcus aureus (MRSA) RN4220/pUL5054 and inhibition of MRSA pyruvate kinase. | 2013 | Phytomedicine | pmid:23541215 |
Tarran R et al. | Nonantibiotic macrolides prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume depletion. | 2013 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:23542952 |