erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Weber JM et al. | An erythromycin process improvement using the diethyl methylmalonate-responsive (Dmr) phenotype of the Saccharopolyspora erythraea mutB strain. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22048617 |
Moncrieffe MC et al. | Structure of the glycosyltransferase EryCIII in complex with its activating P450 homologue EryCII. | 2012 | J. Mol. Biol. | pmid:22056329 |
Shimada M et al. | Corneal ulcer associated with pepper spray exposure during military training. | 2012 | J Emerg Med | pmid:22100497 |
Popowska M et al. | Influence of soil use on prevalence of tetracycline, streptomycin, and erythromycin resistance and associated resistance genes. | 2012 | Antimicrob. Agents Chemother. | pmid:22203596 |
Chouchani C et al. | First report of mefA and msrA/msrB multidrug efflux pumps associated with blaTEM-1 β-lactamase in Enterococcus faecalis. | 2012 | Int. J. Infect. Dis. | pmid:22137270 |
Zou X et al. | Real-time fluid dynamics investigation and physiological response for erythromycin fermentation scale-up from 50 L to 132 m3 fermenter. | 2012 | Bioprocess Biosyst Eng | pmid:22139481 |
McCusker KP and Fujimori DG | The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance. | 2012 | ACS Chem. Biol. | pmid:22208312 |
Ducrotté P and Gourcerol G | [Gastroparesis: pathophysiology and management]. | 2012 | Presse Med | pmid:22154929 |
Back EE et al. | High rates of perinatal group B Streptococcus clindamycin and erythromycin resistance in an upstate New York hospital. | 2012 | Antimicrob. Agents Chemother. | pmid:22143529 |
Perić M et al. | Antimalarial activity of 9a-N substituted 15-membered azalides with improved in vitro and in vivo activity over azithromycin. | 2012 | J. Med. Chem. | pmid:22148880 |
Reil M et al. | Seasonality of Clostridium difficile infections in Southern Germany. | 2012 | Epidemiol. Infect. | pmid:22152928 |
Biester EM et al. | Identification of avian wax synthases. | 2012 | BMC Biochem. | pmid:22305293 |
Jaglic Z et al. | Distribution, characterization and genetic bases of erythromycin resistance in staphylococci and enterococci originating from livestock. | 2012 | Zoonoses Public Health | pmid:21843202 |
Shiu WK et al. | Antibacterial acylphloroglucinols from Hypericum olympicum. | 2012 | J. Nat. Prod. | pmid:21899267 |
Boswihi SS et al. | Serotypes and antibiotic resistance in Group B streptococcus isolated from patients at the Maternity Hospital, Kuwait. | 2012 | J. Med. Microbiol. | pmid:21903822 |
Sadeghi SJ et al. | Drug-drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4. | 2012 | Bioelectrochemistry | pmid:22480862 |
Nunoi H et al. | A relationship between motilin and growth hormone secretagogue receptors. | 2012 | Regul. Pept. | pmid:22465164 |
Jada S et al. | Design and synthesis of novel magnolol derivatives as potential antimicrobial and antiproliferative compounds. | 2012 | Eur J Med Chem | pmid:22424614 |
Osman KM et al. | Antimicrobial susceptibility and molecular typing of multiple Chlamydiaceae species isolated from genital infection of women in Egypt. | 2012 | Microb. Drug Resist. | pmid:22455539 |
Saxena S et al. | Practical disk diffusion method for detection of inducible clindamycin resistance in Staphylococcus aureus at a tertiary care hospital: implications for clinical therapy. | 2012 | J Commun Dis | pmid:25151754 |
Lialikov SA et al. | [Monitoring of side effects and estimation of cycloferon efficacy in treatment of children with frequent and prolonged diseases]. | 2012 | Antibiot. Khimioter. | pmid:23700934 |
Yiannakopoulou E et al. | Pharmacological modulation of oxidative stress response in minimally invasive surgery: systematic review. | 2012 | Surg Laparosc Endosc Percutan Tech | pmid:22678313 |
Bai J et al. | Erythromycin enhances CD4+Foxp3+ regulatory T-cell responses in a rat model of smoke-induced lung inflammation. | 2012 | Mediators Inflamm. | pmid:22701274 |
Vázquez-Sánchez D et al. | Incidence and characterization of Staphylococcus aureus in fishery products marketed in Galicia (Northwest Spain). | 2012 | Int. J. Food Microbiol. | pmid:22704064 |
Correa AM et al. | [Pneumococcal bacteremia in adult patients at a hospital in Madrid: serotypes and susceptibility]. | 2012 | Rev Esp Quimioter | pmid:22707105 |
Teodoro CR et al. | Characterization of MLS(b) resistance among Staphylococcus aureus and Staphylococcus epidermidis isolates carrying different SCCmec types. | 2012 | Microbiol. Immunol. | pmid:22672011 |
Laurens C et al. | Clinical and antimicrobial susceptibility data of 140 Streptococcus pseudopneumoniae isolates in France. | 2012 | Antimicrob. Agents Chemother. | pmid:22644030 |
Thumu SC and Halami PM | Presence of erythromycin and tetracycline resistance genes in lactic acid bacteria from fermented foods of Indian origin. | 2012 | Antonie Van Leeuwenhoek | pmid:22644346 |
Maeda Y et al. | UV-C-irradiation sublethal stress does not alter antibiotic susceptibility of the viridans group streptococci to β-lactam, macrolide, and fluoroquinolone antibiotic agents. | 2012 | J Investig Clin Dent | pmid:22887906 |
Hossein nia R et al. | An expeditious regioselective synthesis of novel bioactive indole-substituted chromene derivatives via one-pot three-component reaction. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22892120 |
Chuang CC et al. | Staphylococcus aureus ocular infection: methicillin-resistance, clinical features, and antibiotic susceptibilities. | 2012 | PLoS ONE | pmid:22880135 |
Block SL | Etiologic and therapeutic pitfalls of newborn conjunctivitis. | 2012 | Pediatr Ann | pmid:22881420 |
Ishibashi K et al. | Usefulness of sennoside as an agent for mechanical bowel preparation prior to elective colon cancer surgery. | 2012 | Asian J Surg | pmid:22720863 |
Molnari JC and Myers AL | Carbonyl reduction of bupropion in human liver. | 2012 | Xenobiotica | pmid:22339467 |
Chiba Y et al. | Mechanism for folate-independent aldolase reaction catalyzed by serine hydroxymethyltransferase. | 2012 | FEBS J. | pmid:22141341 |
Nelson CG and Burke TR | Samarium iodide-mediated Reformatsky reactions for the stereoselective preparation of β-hydroxy-γ-amino acids: synthesis of isostatine and dolaisoleucine. | 2012 | J. Org. Chem. | pmid:22136325 |
Zhou X et al. | Marthiapeptide A, an anti-infective and cytotoxic polythiazole cyclopeptide from a 60 L scale fermentation of the deep sea-derived Marinactinospora thermotolerans SCSIO 00652. | 2012 | J. Nat. Prod. | pmid:23215246 |
Noto MJ and Wheeler AP | Macrolides for acute lung injury. | 2012 | Chest | pmid:22553255 |
Rocco L et al. | Micronucleus test and comet assay for the evaluation of zebrafish genomic damage induced by erythromycin and lincomycin. | 2012 | Environ. Toxicol. | pmid:21384490 |
Milberg P et al. | Blockade of I(Ca) suppresses early afterdepolarizations and reduces transmural dispersion of repolarization in a whole heart model of chronic heart failure. | 2012 | Br. J. Pharmacol. | pmid:22013922 |
Kelley C et al. | 3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents. | 2012 | Bioorg. Med. Chem. | pmid:23127490 |
Parhi A et al. | Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives. | 2012 | Bioorg. Med. Chem. Lett. | pmid:23084900 |
Benet LZ | A step closer to personalized chemotherapy: consideration of the influence of genetic variation in hepatic uptake transporters on the metabolism of CYP3A substrates. | 2012 | Clin. Pharmacol. Ther. | pmid:23085879 |
Lu S and Zgurskaya HI | Role of ATP binding and hydrolysis in assembly of MacAB-TolC macrolide transporter. | 2012 | Mol. Microbiol. | pmid:23057817 |
Laine L and Jensen DM | Management of patients with ulcer bleeding. | 2012 | Am. J. Gastroenterol. | pmid:22310222 |
Waseem S et al. | Spectrum of gastroparesis in children. | 2012 | J. Pediatr. Gastroenterol. Nutr. | pmid:22314391 |
Koning S et al. | Interventions for impetigo. | 2012 | Cochrane Database Syst Rev | pmid:22258953 |
Zhou Q et al. | SigB-dependent tolerance to protein synthesis-inhibiting antibiotics in Listeria monocytogenes EGDe. | 2012 | Curr. Microbiol. | pmid:22143398 |
Lancaster CS et al. | OATP1B1 polymorphism as a determinant of erythromycin disposition. | 2012 | Clin. Pharmacol. Ther. | pmid:22990751 |
Rubio-López V et al. | Molecular epidemiology, antimicrobial susceptibilities and resistance mechanisms of Streptococcus pyogenes isolates resistant to erythromycin and tetracycline in Spain (1994-2006). | 2012 | BMC Microbiol. | pmid:22998619 |