erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Brisaert M et al. | Investigation of the chemical stability of an erythromycin-tretinoin lotion by the use of an optimization system. | 2000 | Int J Pharm | pmid:10704802 |
Bernabéu JA et al. | Microbiological bioassay of erythromycin thiocyanate: optimisation and validation. | 1999 | J Pharm Biomed Anal | pmid:10703990 |
Suri A et al. | Effects of CYP3A inhibition on the metabolism of cilostazol. | 1999 | Clin Pharmacokinet | pmid:10702888 |
Timosca S et al. | [Bacteremia following tooth extractions]. | 1976 | Rev Stomatol Chir Maxillofac | pmid:1070098 |
Hill BC et al. | A simplified method for testing Bordetella pertussis for resistance to erythromycin and other antimicrobial agents. | 2000 | J. Clin. Microbiol. | pmid:10699011 |
Vardy SJ and Rose GE | Prevention of cellulitis after open lacrimal surgery: a prospective study of three methods. | 2000 | Ophthalmology | pmid:10690832 |
Thwaites RT and Frost JA | Drug resistance in Campylobacter jejuni, C coli, and C lari isolated from humans in north west England and Wales, 1997. | 1999 | J. Clin. Pathol. | pmid:10690169 |
Noerr B | Erythromycin. | 1999 | Neonatal Netw | pmid:10690102 |
Yamano K et al. | Quantitative prediction of metabolic inhibition of midazolam by erythromycin, diltiazem, and verapamil in rats: implication of concentrative uptake of inhibitors into liver. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10688631 |
Fail PA et al. | Comparative effects of quinacrine and erythromycin in adult female rats: a nonsurgical sterilization study. | 2000 | Fertil. Steril. | pmid:10685548 |
Berg TG et al. | Ureaplasma/Mycoplasma-infected amniotic fluid: pregnancy outcome in treated and nontreated patients. | 1999 | J Perinatol | pmid:10685238 |
Tang X and Cheng D | [The value of erythromycin pleurodesis in the treatment of malignant pleural effusions]. | 1997 | Hua Xi Yi Ke Da Xue Xue Bao | pmid:10683963 |
Poyart C et al. | Characterization of the Tn916-like transposon Tn3872 in a strain of abiotrophia defectiva (Streptococcus defectivus) causing sequential episodes of endocarditis in a child. | 2000 | Antimicrob. Agents Chemother. | pmid:10681362 |
Kohri K et al. | Macrolide antibiotics inhibit nitric oxide generation by rat pulmonary alveolar macrophages. | 2000 | Eur. Respir. J. | pmid:10678622 |
Biddle JW and Thornsberry C | In vitro activity of rosamicin, josamycin, erythromycin, and clindamycin against beta-lactamase-nagative and beta-lactamase-positive strains of Neisseria gonorrhoeae. | 1979 | Antimicrob. Agents Chemother. | pmid:106776 |
Holen S | Antibiotics used traditionally in periodontal therapy. | 1976 | J. Periodontol. | pmid:1067412 |
Gibson J et al. | Oral staphylococcal mucositis: A new clinical entity in orofacial granulomatosis and Crohn's disease. | 2000 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod | pmid:10673652 |
Munroe CO and Lazarus TL | Prevention of infective endocarditis. | 1976 | Dent J | pmid:1067255 |
Mordi MN et al. | Acid-catalyzed degradation of clarithromycin and erythromycin B: a comparative study using NMR spectroscopy. | 2000 | J. Med. Chem. | pmid:10669574 |
Moutard I et al. | In vitro effects of spiramycin and dirithromycin on IL1 beta production by human LPS-stimulated mononuclear cells. | 1999 Sep-Oct | Therapie | pmid:10667098 |
Tang L et al. | Formation of functional heterologous complexes using subunits from the picromycin, erythromycin and oleandomycin polyketide synthases. | 2000 | Chem. Biol. | pmid:10662693 |
Wilkinson B et al. | Novel octaketide macrolides related to 6-deoxyerythronolide B provide evidence for iterative operation of the erythromycin polyketide synthase. | 2000 | Chem. Biol. | pmid:10662692 |
Descheemaeker P et al. | Macrolide resistance and erythromycin resistance determinants among Belgian Streptococcus pyogenes and Streptococcus pneumoniae isolates. | 2000 | J. Antimicrob. Chemother. | pmid:10660498 |
From the Centers for Disease Control and Prevention. Hypertrophic pyloric stenosis in infants following pertussis prophylaxis with erythromycin--Knoxville, Tennessee, 1999. | 2000 | JAMA | pmid:10659863 | |
Nakahara S et al. | Bronchial amyloidosis successfully treated with low-dose long-term erythromycin therapy. | 1999 | Kurume Med J | pmid:10659597 |
Allevi P et al. | A new convenient transformation of erythromycin A into clarithromycin. | 1999 | Bioorg. Med. Chem. | pmid:10658579 |
Tsutsumi M et al. | Inhibitory effects of combined administration of antibiotics and anti-inflammatory drugs on lung tumor development initiated by N-nitrosobis(2-hydroxypropyl)amine in rats. | 2000 | Carcinogenesis | pmid:10657965 |
Mackinnon AM | The problem of intrahepatic cholestasis. | 1975 | Aust N Z J Med | pmid:1065291 |
Medhus AW et al. | Low-dose intravenous erythromycin: effects on postprandial and fasting motility of the small bowel. | 2000 | Aliment. Pharmacol. Ther. | pmid:10651665 |
Heidenreich A et al. | Gastroparesis after retroperitoneal surgery successfully treated with erythromycin. | 2000 | J. Urol. | pmid:10647677 |
Lebwohl M et al. | Clinically significant therapeutic interactions for the practicing dermatologist. | 1999 | Adv Dermatol | pmid:10643493 |
Santos R et al. | Bacillary angiomatosis by Bartonella quintana in an HIV-infected patient. | 2000 | J. Am. Acad. Dermatol. | pmid:10642694 |
Sharma PK et al. | Erythromycin in pityriasis rosea: A double-blind, placebo-controlled clinical trial. | 2000 | J. Am. Acad. Dermatol. | pmid:10642679 |
Honma Y et al. | Effect of erythromycin on Shigella infection of Caco-2 cells. | 2000 | FEMS Immunol. Med. Microbiol. | pmid:10640609 |
Brueggemann AB et al. | In vitro activity of ABT-773, a new ketolide, against recent clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. | 2000 | Antimicrob. Agents Chemother. | pmid:10639382 |
Gisby J and Bryant J | Efficacy of a new cream formulation of mupirocin: comparison with oral and topical agents in experimental skin infections. | 2000 | Antimicrob. Agents Chemother. | pmid:10639346 |
Bajic S et al. | Analysis of erythromycin by liquid chromatography/mass spectrometry using involatile mobile phases with a novel atmospheric pressure ionization source. | 2000 | Rapid Commun. Mass Spectrom. | pmid:10637421 |
Wu YJ | Highlights of semi-synthetic developments from erythromycin A. | 2000 | Curr. Pharm. Des. | pmid:10637376 |
MartÃnez-Maldonado M | Postinfectious glomerulonephritis. | 2000 | Am. J. Kidney Dis. | pmid:10636819 |
Nasrin D et al. | Antibiotic resistance in Streptococcus pneumoniae isolated from children. | 1999 | J Paediatr Child Health | pmid:10634983 |
Hypertrophic pyloric stenosis in infants following pertussis prophylaxis with erythromycin--Knoxville, Tennessee, 1999. | 1999 | MMWR Morb. Mortal. Wkly. Rep. | pmid:10634345 | |
Weston WL and Morelli JG | Steroid rosacea in prepubertal children. | 2000 | Arch Pediatr Adolesc Med | pmid:10632252 |
Puri SK and Singh N | Azithromycin: antimalarial profile against blood- and sporozoite-induced infections in mice and monkeys. | 2000 | Exp. Parasitol. | pmid:10631075 |
Trinkle R | Comment: evaluation of the clinical and financial impact of intravenous erythromycin therapy in hospitalized patients. | 1999 | Ann Pharmacother | pmid:10630842 |
Sullivan S et al. | Stevens-Johnson syndrome secondary to erythromycin. | 1999 | Ann Pharmacother | pmid:10630839 |
GarcÃa Sánchez MJ et al. | [Bacterial resistances]. | 1999 | Aten Primaria | pmid:10630037 |
Lagrou K et al. | Macrolide resistance in Belgian Streptococcus pneumoniae. | 2000 | J. Antimicrob. Chemother. | pmid:10629023 |
Gallardo MA and Thomas I | Hypersensitivity reaction to erythromycin. | 1999 | Cutis | pmid:10626100 |
Kdesh A et al. | Effect of erythromycin on myocardial repolarization in patients with community-acquired pneumonia. | 1999 | South. Med. J. | pmid:10624910 |
Desaki M et al. | Erythromycin suppresses nuclear factor-kappaB and activator protein-1 activation in human bronchial epithelial cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10623585 |