erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Valsecchi R and Cainelli T | Gingival hyperplasia induced by erythromycin. | 1992 | Acta Derm. Venereol. | pmid:1350410 |
| Ingham E | The effects of tetracyclines and erythromycin on complement activation in vitro. | 1990 | Acta Derm. Venereol. | pmid:1981435 |
| Mills OH and Kligman AM | Treatment of acne vulgaris with topically applied erythromycin and tretinoin. | 1978 | Acta Derm. Venereol. | pmid:83088 |
| Wennerstrand LM et al. | Homozygous palmoplantar keratoderma type bothnia improved by erythromycin: a case report. | 2004 | Acta Derm. Venereol. | pmid:15503361 |
| Guin JD et al. | Antibiotic sensitivity of comedonal Propionibacterium acnes. | 1979 | Acta Derm. Venereol. | pmid:94223 |
| Ström S et al. | Acute febrile ulcerative conglobate acne with leukemoid reaction. | 1973 | Acta Derm. Venereol. | pmid:4127460 |
| Bøge-Rasmussen T et al. | Demodex folliculorum hominis (Simon): incidence in a normomaterial and in patients under systemic treatment with erythromycin or glucocorticoid. | 1982 | Acta Derm. Venereol. | pmid:6183907 |
| Karvonen SL et al. | Systemic corticosteroid and isotretinoin treatment in cystic acne. | 1993 | Acta Derm. Venereol. | pmid:7906462 |
| Mills O et al. | Bacterial resistance and therapeutic outcome following three months of topical acne therapy with 2% erythromycin gel versus its vehicle. | 2002 | Acta Derm. Venereol. | pmid:12361129 |
| Bowyer A and McColl I | Erythrasma and pruritus ani. | 1971 | Acta Derm. Venereol. | pmid:4109425 |
| Gudjónsson H | Experiments to induce febrile Jarisch-Herxheimer reaction in syphilitic rabbits with penicillin and erythromycin. | 1972 | Acta Derm. Venereol. | pmid:4118397 |
| Schmidt H et al. | Bacteriological examination of rectal specimen during long-term oxytetracycline treatment for acne vulgaris. | 1973 | Acta Derm. Venereol. | pmid:4120960 |
| Worm AM | Roxithromycin and erythromycin in chlamydia-negative non-gonococcal urethritis. | 1990 | Acta Derm. Venereol. | pmid:1972850 |
| Leyden JJ et al. | Topical antibiotics and topical antimicrobial agents in acne therapy. | 1980 | Acta Derm Venereol Suppl (Stockh) | pmid:6451130 |
| Holm SE and Burman LG | General considerations by a clinical bacteriologist regarding antibiotic therapy in acne. | 1980 | Acta Derm Venereol Suppl (Stockh) | pmid:6451131 |
| Kligman AM et al. | Acne therapy with tretinoin in combination with antibiotics. | 1975 Jan 27-29 | Acta Derm Venereol Suppl (Stockh) | pmid:130772 |
| Sanchez MA and Rorat E | Fine needle aspiration diagnosis of intramuscular bacillary angiomatosis. A case report. | 1996 Jul-Aug | Acta Cytol. | pmid:8693899 |
| Bertini B et al. | Cytopathology of nipple discharge due to Pityrosporum orbiculare and cocci in an elderly woman. | 1975 Jan-Feb | Acta Cytol. | pmid:46660 |
| Davydova N et al. | Crystals of a mutant form of ribosomal protein L22 rendering bacterial ribosomes resistant to erythromycin. | 2001 | Acta Crystallogr. D Biol. Crystallogr. | pmid:11468402 |
| Lynch VM et al. | A novel dioxabicyclo[3.3.1]nonane, a key intermediate in the synthesis of erythronolide B seco-acid. | 1994 | Acta Crystallogr C | pmid:7946151 |