erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hearing Loss, Conductive D006314 2 associated lipids
Common Cold D003139 2 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Uterine Cervical Erosion D002579 2 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Tooth Diseases D014076 2 associated lipids
Animal Diseases D000820 2 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Auditory Diseases, Central D001304 2 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Angiomatosis, Bacillary D016917 2 associated lipids
Torsades de Pointes D016171 2 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Diphtheria D004165 2 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Eye Infections, Parasitic D015822 2 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Jejunal Diseases D007579 3 associated lipids
Pleuropneumonia D011001 3 associated lipids
Labyrinth Diseases D007759 3 associated lipids
Hypersplenism D006971 3 associated lipids
Pityriasis D010915 3 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Gangrene D005734 3 associated lipids
Pulmonary Emphysema D011656 3 associated lipids
Tourette Syndrome D005879 3 associated lipids
Ileus D045823 3 associated lipids
Keratoconjunctivitis D007637 3 associated lipids
Otorhinolaryngologic Diseases D010038 3 associated lipids
Acneiform Eruptions D017486 3 associated lipids
Typhus, Endemic Flea-Borne D014437 3 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Sporotrichosis D013174 3 associated lipids
Pleural Effusion D010996 3 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Radiodermatitis D011855 3 associated lipids
Intestinal Atresia D007409 3 associated lipids
Fever of Unknown Origin D005335 3 associated lipids
Dry Socket D004368 3 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Empyema D004653 3 associated lipids
Erythema Multiforme D004892 3 associated lipids
Haemophilus Infections D006192 3 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Conjunctivitis, Bacterial D003234 3 associated lipids
Surgical Wound Dehiscence D013529 3 associated lipids
Relapsing Fever D012061 3 associated lipids
Pneumonia, Pneumococcal D011018 3 associated lipids
Orthomyxoviridae Infections D009976 3 associated lipids
Superinfection D015163 3 associated lipids
Scleritis D015423 3 associated lipids
Toothache D014098 3 associated lipids
Meningitis, Haemophilus D008583 3 associated lipids
Uterine Cervical Incompetence D002581 3 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Bartonella Infections D001474 3 associated lipids
Fractures, Open D005597 3 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Impetigo D007169 3 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Heart Block D006327 3 associated lipids
Bursitis D002062 3 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Diarrhea, Infantile D003968 3 associated lipids
Legionellosis D007876 3 associated lipids
Foot Diseases D005534 4 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Parotitis D010309 4 associated lipids
Red-Cell Aplasia, Pure D012010 4 associated lipids
Splenomegaly D013163 4 associated lipids
Syphilis, Latent D013592 4 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Blepharitis D001762 4 associated lipids
Duodenitis D004382 4 associated lipids
Peptic Ulcer Hemorrhage D010438 4 associated lipids
Quadriplegia D011782 4 associated lipids
Endocarditis D004696 4 associated lipids
Aortic Valve Stenosis D001024 4 associated lipids
Lymphangitis D008205 4 associated lipids
Foot Ulcer D016523 4 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Pharyngeal Diseases D010608 4 associated lipids
Lymphogranuloma Venereum D008219 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Inappropriate ADH Syndrome D007177 4 associated lipids
Ergotism D004881 4 associated lipids
Urethral Diseases D014522 4 associated lipids
Streptococcal Infections D013290 4 associated lipids
Otitis Media, Suppurative D010035 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Jaglic Z et al. Distribution, characterization and genetic bases of erythromycin resistance in staphylococci and enterococci originating from livestock. 2012 Zoonoses Public Health pmid:21843202
Berger A et al. Two cases of cutaneous diphtheria associated with occupational pig contact in Germany. 2013 Zoonoses Public Health pmid:23280311
Campagnolo ER et al. Pet-associated Campylobacteriosis: A persisting public health concern. 2018 Zoonoses Public Health pmid:28834267
Pan DY et al. Effect of oral erythromycin on patients with diabetic gastroparesis. 1995 Zhonghua Yi Xue Za Zhi (Taipei) pmid:7634182
Jang TN et al. A randomized comparative study on the safety and efficacy of clarithromycin and erythromycin in treating community-acquired pneumonia. 1995 Zhonghua Yi Xue Za Zhi (Taipei) pmid:7796357
Ko YY et al. Recurrent infection of Legionella pneumonia: a case report. 1996 Zhonghua Yi Xue Za Zhi (Taipei) pmid:8768386
Tai CY et al. [Bullous epidermolytic and atrophic dermatitis medicamentosa: report of 4 cases]. 1974 Zhonghua Yi Xue Za Zhi pmid:4273908
Cai XJ et al. [Protective effects of erythromycin on human bronchial epithelial cells impaired by interleukin-4]. 2011 Zhonghua Yi Xue Za Zhi pmid:22094097
Bai H et al. [Susceptibility study on urogenital Chlamydia trachomatis to 19 kinds of antibiotics]. 1995 Zhonghua Yi Xue Za Zhi pmid:7600311
Wang J et al. [Drug susceptibility and homologous analysis on Corynebacterium striatum strains isolated from inpatients]. 2014 Zhonghua Yi Xue Za Zhi pmid:25410920
Lü P et al. [Transfer of erythromycin-resistance among strains and species of bacteria: plasmid conjugation method in enterococcal isolates]. 2007 Zhonghua Yi Xue Za Zhi pmid:17988534
Chen DK et al. [Mechanism of hetero-erythromycin resistant Staphylococcus aureus and a comparison of detection methods]. 2013 Zhonghua Yi Xue Za Zhi pmid:24548451
He ZY et al. [Effects of erythromycin on hydrogen peroxide-induced interleukin-8 synthesis and regulation of glutathione in human bronchial epithelial cells]. 2005 Zhonghua Yi Xue Za Zhi pmid:16061006
Shi HY et al. [Effect of quorum sensing system on the infection of MRSA and the intervention of erythromycin on it]. 2016 Zhonghua Yi Xue Za Zhi pmid:27760665
Shi X et al. [The research of the innate defense regulator peptide on the effects of methicillin resistant staphylococcus aureus biofilm]. 2018 Zhonghua Yi Xue Za Zhi pmid:29397617
Li LH et al. [Effect of low dose erythromycin on the proliferation of granulation tissue after tracheal injury]. 2017 Zhonghua Yi Xue Za Zhi pmid:28316160
Chen SZ et al. [Erythromycin inhibits the proliferation of HERG K+ channel highly expressing cancer cells and shows synergy with anticancer drugs]. 2006 Zhonghua Yi Xue Za Zhi pmid:17313833
Liu CL et al. [Current infection of Mycoplasma pneumoniae in adults: clinical analysis of 13 hospitalized patients]. 2006 Zhonghua Yi Xue Za Zhi pmid:16796860
Chang HY et al. [The study on reversing mechanism of multidrug resistance of K562/A02 cell line by curcumin and erythromycin]. 2006 Zhonghua Xue Ye Xue Za Zhi pmid:16875558
Luan R et al. [Erythromycin for improving enteral nutrition tolerance in adult critical patients: a systematic review and meta-analysis]. 2014 Zhonghua Wei Zhong Bing Ji Jiu Yi Xue pmid:24912643
Liu JF et al. [Effect of erythromycin on electrical activity and gastric emptying of the intrathoracic stomach after esophagectomy for esophageal cancer]. 2013 Zhonghua Wei Chang Wai Ke Za Zhi pmid:24061999
Fu D et al. [Contractile effect of erythromycin on the gallbladder]. 1995 Zhonghua Wai Ke Za Zhi pmid:8762558
Zhou Y et al. [Detection and the antibiotic susceptibility analysis of mycoplasma and chlamydia in urogenital tract infections of 327 cases patients with tubal infertility]. 2011 Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi pmid:21977592
Feng B et al. [Acetaminophen absorption test for determination of diabetic gastroparesis and effects of erythromycin on gastric emptying]. 1996 Zhonghua Nei Ke Za Zhi pmid:9387657
Song JF et al. [Resistant rate to antibiotics in Tian Tan Hospital for 3 years]. 1992 Zhonghua Nei Ke Za Zhi pmid:1303851
Wang X et al. [Effects of changes of plasma motilin level on the motility of gallbladder in patients with chronic renal failure]. 1996 Zhonghua Nei Ke Za Zhi pmid:9275623
Chen J et al. [An experimental study on the effect of azithromycin treatment in bleomycin-induced pulmonary fibrosis of rats]. 1999 Zhonghua Nei Ke Za Zhi pmid:11798706
Zhao TM and Liu YN [The phenotype and genotype patterns of erythromycin-resistant Streptococcus pneumoniae]. 2004 Zhonghua Nei Ke Za Zhi pmid:15182500
Liu YG et al. [Clinical study of erythromycin action on gallbladder motility in patients with non-ulcer dyspepsia]. 1994 Zhonghua Nei Ke Za Zhi pmid:7867425
Su BH et al. Effect of erythromycin on feeding intolerance in very low birth weight infants: a preliminary observation. 1998 Sep-Oct Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi pmid:9823678
LEE PP et al. [CASE OF POLIO-LIKE DISEASE DUE TO COXSACKIE A 7 VIRUS]. 1964 Jul-Sep Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi pmid:14213951
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Chang JC et al. In vitro postantibiotic effect of roxithromycin and erythromycin against gram-positive cocci. 1992 Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi pmid:1342645
Ding YF et al. [Study on the molecule epidemiological between resistances of 7 genes interrelated 4 antibiotic to isolated Streptococcus pneumoniae in children]. 2005 Zhonghua Liu Xing Bing Xue Za Zhi pmid:16185459
Wen B [Observation on clinical features and therapy in 4 elderly cases with legionellosis]. 1991 Zhonghua Liu Xing Bing Xue Za Zhi pmid:1863947
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He JL et al. [Distribution of anaerobes in periodontal abscess and its resistance to antibiotics]. 2012 Zhonghua Kou Qiang Yi Xue Za Zhi pmid:23328096
Yuan H et al. [The effect of erythromycin on transforming growth factor-β(1) and secretory leukocyte proteinase inhibitor in a rat model of chronic obstructive pulmonary disease]. 2011 Zhonghua Jie He He Hu Xi Za Zhi pmid:22041779
Fan L and Xu J [Application progress of macrolide sustained therapy for bronchiectasis]. 2014 Zhonghua Jie He He Hu Xi Za Zhi pmid:24694975
Yu L and Ran PX [Effects of erythromycin on the synthesis of interleukin-8 and gamma-glutamylcysteine synthetase induced by 4-hydroxynonenal in the bronchial epithelial cells]. 2009 Zhonghua Jie He He Hu Xi Za Zhi pmid:19567187
Xiao W et al. [The imbalance of Th1/Th2 cytokine expression in peripheral blood mononuclear cell from asthmatic patients and the effect of erythromycin on these cytokines]. 2000 Zhonghua Jie He He Hu Xi Za Zhi pmid:11778516
Gao W et al. [Analysis of 9 cases of pulmonary tuberculosis complicated with legionnaires disease]. 1997 Zhonghua Jie He He Hu Xi Za Zhi pmid:10374448
Xu Z et al. [Effects of erythromycin and fosfomycin on Pseudomonas aeruginosa biofilm in vitro]. 2001 Zhonghua Jie He He Hu Xi Za Zhi pmid:11802985
Gu XH et al. [Effects of erythromycin on the twitching motility of Pseudomonas aeruginosa]. 2007 Zhonghua Jie He He Hu Xi Za Zhi pmid:17573001
Zhong XN and Guo SM [An experimental study on pulmonary vascular inflammation in a rat model of chronic bronchitis and emphysema]. 2006 Zhonghua Jie He He Hu Xi Za Zhi pmid:17045040
Liu J et al. [mRNA expression of basic fibroblast growth factor in the pulmonary tissues from rats repeatedly infected with mycoplasma pneumoniae]. 1999 Zhonghua Jie He He Hu Xi Za Zhi pmid:11775917
Li Y et al. [The effect of erythromycin on NF-kappa B activation and cytokines mRNA expression in bleomycin-induced pulmonary fibrosis in rats]. 1999 Zhonghua Jie He He Hu Xi Za Zhi pmid:11776779
Lu W et al. [Analysis of 37 cases of pneumonia of Legionnaires' disease]. 1997 Zhonghua Jie He He Hu Xi Za Zhi pmid:10072832