erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Chen C et al. | Blocking the flow of propionate into TCA cycle through a mutB knockout leads to a significant increase of erythromycin production by an industrial strain of Saccharopolyspora erythraea. | 2017 | Bioprocess Biosyst Eng | pmid:27709326 |
Pérez RA et al. | Analysis of macrolide antibiotics in water by magnetic solid-phase extraction and liquid chromatography-tandem mass spectrometry. | 2017 | J Pharm Biomed Anal | pmid:28858671 |
Zankari E et al. | PointFinder: a novel web tool for WGS-based detection of antimicrobial resistance associated with chromosomal point mutations in bacterial pathogens. | 2017 | J. Antimicrob. Chemother. | pmid:29091202 |
Giguère S et al. | Antimicrobial Resistance in . | 2017 | Microbiol Spectr | pmid:29052538 |
Liu J et al. | Interaction of erythromycin and ketoconazole on the neurological, biochemical and behavioral responses in crucian carp. | 2017 | Environ. Toxicol. Pharmacol. | pmid:28802958 |
Lee JK et al. | Changes in the Serotype Distribution among Antibiotic Resistant Carriage Streptococcus pneumoniae Isolates in Children after the Introduction of the Extended-Valency Pneumococcal Conjugate Vaccine. | 2017 | J. Korean Med. Sci. | pmid:28776337 |
Jakkidi M et al. | An illusion of septic shock: acute generalised exanthematous pustulosis with multiorgan dysfunction. | 2017 | BMJ Case Rep | pmid:28768672 |
Cluver C et al. | Interventions for treating genital Chlamydia trachomatis infection in pregnancy. | 2017 | Cochrane Database Syst Rev | pmid:28937705 |
Tran LTC et al. | Erythromycin encapsulation in nanoemulsion-based delivery systems for treatment of Helicobacter pylori infection: Protection and synergy. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28917836 |
Gonser LI et al. | Systemic therapy of ocular and cutaneous rosacea in children. | 2017 | J Eur Acad Dermatol Venereol | pmid:28621909 |
Tintino SR et al. | Tannic acid affects the phenotype of Staphylococcus aureus resistant to tetracycline and erythromycin by inhibition of efflux pumps. | 2017 | Bioorg. Chem. | pmid:28841421 |
Ji W et al. | Colonization prevalence and antibiotic susceptibility of Group B Streptococcus in pregnant women over a 6-year period in Dongguan, China. | 2017 | PLoS ONE | pmid:28813477 |
Mingmongkolchai S and Panbangred W | In vitro evaluation of candidate Bacillus spp. for animal feed. | 2017 | J. Gen. Appl. Microbiol. | pmid:28331163 |
Attaran B et al. | Effect of biofilm formation by clinical isolates of on the efflux-mediated resistance to commonly used antibiotics. | 2017 | World J. Gastroenterol. | pmid:28275296 |
Nowakiewicz A et al. | Determination of antimicrobial resistance of Enterococcus strains isolated from pigs and their genotypic characterization by method of amplification of DNA fragments surrounding rare restriction sites (ADSRRS fingerprinting). | 2017 | J. Med. Microbiol. | pmid:28260584 |
Hodge S et al. | Nonantibiotic macrolides restore airway macrophage phagocytic function with potential anti-inflammatory effects in chronic lung diseases. | 2017 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:28258107 |
Lee JH et al. | Genetic Diversity and Antibiotic Resistance of Enterococcus faecalis Isolates from Traditional Korean Fermented Soybean Foods. | 2017 | J. Microbiol. Biotechnol. | pmid:28237994 |
Descours G et al. | Ribosomal Mutations Conferring Macrolide Resistance in Legionella pneumophila. | 2017 | Antimicrob. Agents Chemother. | pmid:28069647 |
Berni E et al. | Risk of cardiovascular events, arrhythmia and all-cause mortality associated with clarithromycin versus alternative antibiotics prescribed for respiratory tract infections: a retrospective cohort study. | 2017 | BMJ Open | pmid:28115334 |
Wei L et al. | Transformation of erythromycin during secondary effluent soil aquifer recharging: Removal contribution and degradation path. | 2017 | J Environ Sci (China) | pmid:28115128 |
Koryakina I et al. | Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering. | 2017 | ACS Chem. Biol. | pmid:28103677 |
Sugimoto N et al. | Invasive pneumococcal disease caused by mucoid serotype 3 Streptococcus pneumoniae: a case report and literature review. | 2017 | BMC Res Notes | pmid:28057059 |
Liu J et al. | Modulation of erythromycin-induced biochemical responses in crucian carp by ketoconazole. | 2017 | Environ Sci Pollut Res Int | pmid:28004371 |
Hillitt KL et al. | Antimicrobial activity of Manuka honey against antibiotic-resistant strains of the cell wall-free bacteria Ureaplasma parvum and Ureaplasma urealyticum. | 2017 | Lett. Appl. Microbiol. | pmid:27992658 |
Numanović F et al. | Presence and resistance of Streptococcus agalactiae in vaginal specimens of pregnant and adult non-pregnant women and association with other aerobic bacteria. | 2017 | Med Glas (Zenica) | pmid:27917849 |
Parthasarathy G et al. | Relationship Between Gastric Emptying and Diurnal Glycemic Control in Type 1 Diabetes Mellitus: A Randomized Trial. | 2017 | J. Clin. Endocrinol. Metab. | pmid:27880079 |
Creti R et al. | Neonatal Group B Streptococcus Infections: Prevention Strategies, Clinical and Microbiologic Characteristics in 7 Years of Surveillance. | 2017 | Pediatr. Infect. Dis. J. | pmid:27870810 |
Zhang W et al. | Isolation and characterization of a high-efficiency erythromycin A-degrading Ochrobactrum sp. strain. | 2017 | Mar. Pollut. Bull. | pmid:27863881 |
Kullin B et al. | Toxin A-negative toxin B-positive ribotype 017 Clostridium difficile is the dominant strain type in patients with diarrhoea attending tuberculosis hospitals in Cape Town, South Africa. | 2017 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:27696234 |
Pavlović D et al. | Synthesis of novel 15-membered 8a-azahomoerythromycin A acylides: Consequences of structural modification at the C-3 and C-6 position on antibacterial activity. | 2017 | Eur J Med Chem | pmid:27657812 |
Lim SK et al. | Macrolide resistance mechanisms and virulence factors in erythromycin-resistant Campylobacter species isolated from chicken and swine feces and carcasses. | 2017 | J. Vet. Med. Sci. | pmid:27593510 |
Zhou X et al. | Erythromycin attenuates metalloprotease/anti-metalloprotease imbalance in cigarette smoke-induced emphysema in rats via the mitogen-activated protein kinase/nuclear factor-κB activation pathway. | 2017 | Mol Med Rep | pmid:28358431 |
Naimi HM et al. | Determination of antimicrobial susceptibility patterns in Staphylococcus aureus strains recovered from patients at two main health facilities in Kabul, Afghanistan. | 2017 | BMC Infect. Dis. | pmid:29187146 |
Ricker EB and Nuxoll E | Synergistic effects of heat and antibiotics on Pseudomonas aeruginosa biofilms. | 2017 | Biofouling | pmid:29039211 |
Bitew A et al. | Species distribution and antibiotic susceptibility profile of bacterial uropathogens among patients complaining urinary tract infections. | 2017 | BMC Infect. Dis. | pmid:28962545 |
Öksüz L and Gürler N | [Serotype distribution and antibiotic resistance of Streptococcus pneumoniae strains isolated from the adult patients in a Turkish üniversity hospital]. | 2017 | Mikrobiyol Bul | pmid:28929957 |
Pan M and Chu LM | Transfer of antibiotics from wastewater or animal manure to soil and edible crops. | 2017 | Environ. Pollut. | pmid:28866424 |
Wekselman I et al. | The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. | 2017 | Structure | pmid:28689968 |
Truong-Bolduc QC et al. | Transcriptional Regulator TetR21 Controls the Expression of the Staphylococcus aureus LmrS Efflux Pump. | 2017 | Antimicrob. Agents Chemother. | pmid:28584148 |
Blackwell GA and Hall RM | The Determinant and the Genes in Acinetobacter Plasmids Are Each Part of Discrete Modules Flanked by Inversely Oriented p (XerC-XerD) Sites. | 2017 | Antimicrob. Agents Chemother. | pmid:28533235 |
Dolberg AM and Reichl S | Activity of Multidrug Resistance-Associated Proteins 1-5 (MRP1-5) in the RPMI 2650 Cell Line and Explants of Human Nasal Turbinate. | 2017 | Mol. Pharm. | pmid:28291371 |
Svetlov MS et al. | Kinetics of drug-ribosome interactions defines the cidality of macrolide antibiotics. | 2017 | Proc. Natl. Acad. Sci. U.S.A. | pmid:29229833 |
Atkinson CT et al. | Expression of acquired macrolide resistance genes in Haemophilus influenzae. | 2017 | J. Antimicrob. Chemother. | pmid:28961896 |
Zhou Z et al. | Combination of Erythromycin and Curcumin Alleviates Induced Osteomyelitis in Rats. | 2017 | Front Cell Infect Microbiol | pmid:28884090 |
Peng Z et al. | Genomic insights into the pathogenicity and environmental adaptability of Enterococcus hirae R17 isolated from pork offered for retail sale. | 2017 | Microbiologyopen | pmid:28799224 |
Zheng PX et al. | Highly prevalent emmSTG840.0 and emmSTC839.0 types of erythromycin non-susceptible group G Streptococcus isolated from bacteremia in southern Taiwan. | 2017 | J Microbiol Immunol Infect | pmid:28711431 |
Wang B et al. | Acid or erythromycin stress significantly improves transformation efficiency through regulating expression of DNA binding proteins in Lactococcus lactis F44. | 2017 | J. Dairy Sci. | pmid:28987584 |
Quinn KL et al. | Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study. | 2017 | Drug Saf | pmid:28421551 |
Zhao L et al. | Occurrence of erythromycin and its degradation products residues in honey. Validation of an analytical method. | 2017 | J Sep Sci | pmid:28121061 |
Dreno B et al. | Skin microbiome and acne vulgaris: Staphylococcus, a new actor in acne. | 2017 | Exp. Dermatol. | pmid:28094874 |