erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Endocarditis, Bacterial D004697 5 associated lipids
Endocarditis, Subacute Bacterial D004698 1 associated lipids
Endometritis D004716 6 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Epidermitis, Exudative, of Swine D004818 1 associated lipids
Epilepsy D004827 35 associated lipids
Ergotism D004881 4 associated lipids
Erysipelas D004886 1 associated lipids
Erythema Multiforme D004892 3 associated lipids
Erythema Nodosum D004893 5 associated lipids
Erythrasma D004894 1 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Eye Diseases D005128 12 associated lipids
Factor X Deficiency D005171 2 associated lipids
Fecal Incontinence D005242 1 associated lipids
Femoral Fractures D005264 7 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Fever D005334 35 associated lipids
Fever of Unknown Origin D005335 3 associated lipids
Focal Infection, Dental D005491 1 associated lipids
Folliculitis D005499 7 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Foot Diseases D005534 4 associated lipids
Fractures, Open D005597 3 associated lipids
Furunculosis D005667 2 associated lipids
Gangrene D005734 3 associated lipids
Gardner Syndrome D005736 2 associated lipids
Gas Gangrene D005738 1 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Tourette Syndrome D005879 3 associated lipids
Glomerulonephritis D005921 35 associated lipids
Gonorrhea D006069 7 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Haemophilus Infections D006192 3 associated lipids
Hand Dermatoses D006229 5 associated lipids
Hearing Disorders D006311 10 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Hearing Loss, Functional D006315 2 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Heart Block D006327 3 associated lipids
Heart Diseases D006331 8 associated lipids
Cardiomegaly D006332 31 associated lipids
Heart Failure D006333 36 associated lipids
Heart Murmurs D006337 1 associated lipids
Hematemesis D006396 1 associated lipids
Hematuria D006417 13 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Hemolysis D006461 131 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Herpes Genitalis D006558 2 associated lipids
Herpes Zoster Ophthalmicus D006563 2 associated lipids
HIV Seropositivity D006679 15 associated lipids
Hoarseness D006685 2 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Hypersplenism D006971 3 associated lipids
Hypertension D006973 115 associated lipids
Hypotension D007022 41 associated lipids
Hypothermia D007035 19 associated lipids
Hypoventilation D007040 2 associated lipids
Impetigo D007169 3 associated lipids
Inappropriate ADH Syndrome D007177 4 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Inflammation D007249 119 associated lipids
Intestinal Atresia D007409 3 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Intraoperative Complications D007431 5 associated lipids
Ischemia D007511 18 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Jejunal Diseases D007579 3 associated lipids
Keratoconjunctivitis D007637 3 associated lipids
Keratoderma, Palmoplantar D007645 1 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Labyrinth Diseases D007759 3 associated lipids
Lacrimal Duct Obstruction D007767 1 associated lipids
Laryngitis D007827 5 associated lipids
Legionellosis D007876 3 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Leishmaniasis D007896 19 associated lipids
Leprosy D007918 8 associated lipids
Leukemia D007938 74 associated lipids
Leukemia P388 D007941 43 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Lipidoses D008064 7 associated lipids
Listeriosis D008088 12 associated lipids
Liver Abscess D008100 6 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Lim KS et al. Antimicrobial susceptibility of bifidobacteria. 1993 J. Dairy Sci. pmid:8408866
Holmberg K et al. Antimicrobial in vitro susceptibility of actinomyces israelii and arachnia propionica. 1977 Scand. J. Infect. Dis. pmid:841278
Ahrens F et al. [Legionellosis in a newborn infant]. 1993 Monatsschr Kinderheilkd pmid:8413346
Saitoh S et al. Mycoplasma pneumoniae infection may cause striatal lesions leading to acute neurologic dysfunction. 1993 Neurology pmid:8413990
Dan M and Feigl D Erythromycin-associated hypotension. 1993 Pediatr. Infect. Dis. J. pmid:8414782
Paradisi M et al. Efficacy of topical erythromycin in treatment of perianal streptococcal dermatitis. 1993 Pediatr Dermatol pmid:8415314
Arayne MS and Sultana N Erythromycin-antacid interaction. 1993 Pharmazie pmid:8415858
Pecevski J et al. The effect of erythromycin and its thiocarbamide derivative on the induction of meiotic chromosome rearrangements in irradiated male mice. 1977 Strahlentherapie pmid:841613
Stassi D et al. Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis. 1993 J. Bacteriol. pmid:8416893
Rello J et al. A three-year study of severe community-acquired pneumonia with emphasis on outcome. 1993 Chest pmid:8417885
Pauker SG and Kopelman RI Weak reasoning: diagnosis by drug reaction. 1993 N. Engl. J. Med. pmid:8419820
Kadota J et al. A mechanism of erythromycin treatment in patients with diffuse panbronchiolitis. 1993 Am. Rev. Respir. Dis. pmid:8420410
Camilleri M The current role of erythromycin in the clinical management of gastric emptying disorders. 1993 Am. J. Gastroenterol. pmid:8424415
Keshavarzian A and Isaac RM Erythromycin accelerates gastric emptying of indigestible solids and transpyloric migration of the tip of an enteral feeding tube in fasting and fed states. 1993 Am. J. Gastroenterol. pmid:8424419
Mantides A et al. The effect of erythromycin in gastric emptying of solids and hypertonic liquids in healthy subjects. 1993 Am. J. Gastroenterol. pmid:8424420
Richards RD et al. The treatment of idiopathic and diabetic gastroparesis with acute intravenous and chronic oral erythromycin. 1993 Am. J. Gastroenterol. pmid:8424421
Bonacini M et al. Effect of intravenous erythromycin on postoperative ileus. 1993 Am. J. Gastroenterol. pmid:8424422
Noah PK et al. Evaluation of oral erythromycin and local isoniazid instillation therapy in infants with Bacillus Calmette-Guérin lymphadenitis and abscesses. 1993 Pediatr. Infect. Dis. J. pmid:8426771
O'Brien JF et al. Dexamethasone as adjuvant therapy for severe acute pharyngitis. 1993 Ann Emerg Med pmid:8427434
Lees AW and Tyrrell WF Diagnosis of legionnaires' disease. 1979 Lancet pmid:84289
Sacristán JA and Soto J Erythromycin ototoxicity: methodology and conclusions. 1993 Am. J. Med. pmid:8430720
Maskin SL Infectious scleritis after a diabetic foot ulcer. 1993 Am. J. Ophthalmol. pmid:8430739
Stacher G et al. Erythromycin effects on gastric emptying, antral motility and plasma motilin and pancreatic polypeptide concentrations in anorexia nervosa. 1993 Gut pmid:8432466
Sladek GG and Frame JN Rhodococcus equi causing bacteremia in an adult with acute leukemia. 1993 South. Med. J. pmid:8434305
Marrie TJ Mycoplasma pneumoniae pneumonia requiring hospitalization, with emphasis on infection in the elderly. 1993 Arch. Intern. Med. pmid:8435028
Roos K et al. Interfering alpha-streptococci as a protection against recurrent streptococcal tonsillitis in children. 1993 Int. J. Pediatr. Otorhinolaryngol. pmid:8436458
Falck G [Therapy of whooping cough. Treatment for the "privileged", what about the others?]. 1993 Lakartidningen pmid:8437454
Knottenbelt DC Rhodococcus equi infection in foals: a report of an outbreak on a thoroughbred stud in Zimbabwe. 1993 Vet. Rec. pmid:8438546
Bartkowski RR et al. Sufentanil disposition. Is it affected by erythromycin administration? 1993 Anesthesiology pmid:8439020
Catnach SM et al. Dose-dependent stimulation of gallbladder contraction by intravenous erythromycin in man. 1993 Aliment. Pharmacol. Ther. pmid:8439638
Carol P et al. Erythromycin and 5S rRNA binding properties of the spinach chloroplast ribosomal protein CL22. 1993 Nucleic Acids Res. pmid:8441674
Fietta A et al. Bioactivity of flurithromycin and other macrolides against intracellular susceptible staphylococci. 1993 Chemotherapy pmid:8444060
Tsakris A and Maniatis AN Inducible type of erythromycin resistance among group B streptococci isolated in Greece. 1993 J. Antimicrob. Chemother. pmid:8444664
Lehtonen L et al. Erythromycin and 2'-acetyl erythromycin concentrations in plasma and pelvic tissues after repeated doses of erythromycin acistrate. 1993 Arzneimittelforschung pmid:8447849
Andersen JF et al. Substrate specificity of 6-deoxyerythronolide B hydroxylase, a bacterial cytochrome P450 of erythromycin A biosynthesis. 1993 Biochemistry pmid:8448148
Chien SM et al. Treatment of community-acquired pneumonia. A multicenter, double-blind, randomized study comparing clarithromycin with erythromycin. Canada-Sweden Clarithromycin-Pneumonia Study Group. 1993 Chest pmid:8449054
Leadlay PF et al. The erythromycin-producing polyketide synthase. 1993 Biochem. Soc. Trans. pmid:8449298
Bevitt DJ et al. Mutagenesis of the dehydratase active site in the erythromycin-producing polyketide synthase. 1993 Biochem. Soc. Trans. pmid:8449310
Roberts GA et al. 6-Deoxyerythronolide B synthase 3 from Saccharopolyspora erythraea: over-expression in Escherichia coli, purification and characterisation. 1993 Biochem. Soc. Trans. pmid:8449313
Ogino J et al. [Effect of erythromycin on anti staphylococcal activity and dye production of Pseudomonas aeruginosa isolated from clinical materials]. 1993 Kansenshogaku Zasshi pmid:8450271
Kusano S et al. [Effect of erythromycin on neutrophil adhesion molecules]. 1993 Kansenshogaku Zasshi pmid:8450276
Echizen H et al. A potent inhibitory effect of erythromycin and other macrolide antibiotics on the mono-N-dealkylation metabolism of disopyramide with human liver microsomes. 1993 J. Pharmacol. Exp. Ther. pmid:8450476
Coonan K and Kaplan EL Therapeutic implications of erythromycin resistance in group A streptococci. 1993 Pediatr. Infect. Dis. J. pmid:8451111
Lindstrom TD et al. Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers. 1993 Antimicrob. Agents Chemother. pmid:8452357
Peterson MC et al. Prosthetic hip infection and bacteremia due to Campylobacter jejuni in a patient with AIDS. 1993 Clin. Infect. Dis. pmid:8452956
Karlowsky J et al. A review of commonly prescribed oral antibiotics in general dentistry. 1993 J Can Dent Assoc pmid:8453530
Olkkola KT et al. A potentially hazardous interaction between erythromycin and midazolam. 1993 Clin. Pharmacol. Ther. pmid:8453848
Edelbroek MA et al. Effects of erythromycin on gastric emptying, alcohol absorption and small intestinal transit in normal subjects. 1993 J. Nucl. Med. pmid:8455074
Clotet B et al. Rhodococcus equi infection in HIV-infected patients. 1993 J. Acquir. Immune Defic. Syndr. pmid:8455149
Spach DH et al. Endocarditis caused by Rochalimaea quintana in a patient infected with human immunodeficiency virus. 1993 J. Clin. Microbiol. pmid:8458964
Hoogeterp JJ et al. Activity of erythromycin and clindamycin in an experimental Staphylococcus aureus infection in normal and granulocytopenic mice. A comparative in vivo and in vitro study. 1993 Scand. J. Infect. Dis. pmid:8460336
Fiorucci S and Morelli A Motilin and erythromycin stimulate pepsinogen secretion by chief cells isolated from guinea pig stomach. 1993 Gastroenterology pmid:8462791
Eady EA et al. Distribution of genes encoding erythromycin ribosomal methylases and an erythromycin efflux pump in epidemiologically distinct groups of staphylococci. 1993 J. Antimicrob. Chemother. pmid:8463168
Mantzoros C et al. Skin lesion in an acutely ill man with HIV. 1993 Hosp. Pract. (Off. Ed.) pmid:8463358
Driscoll MS et al. Long-term oral antibiotics for acne: is laboratory monitoring necessary? 1993 J. Am. Acad. Dermatol. pmid:8463461
Hahn D Erythromycin reduces neutrophils and neutrophil-derived elastolytic-like activity in the lower respiratory tract of bronchiolitis patients. 1993 Am. Rev. Respir. Dis. pmid:8466109
Vasquez EM et al. Clinically significant hearing loss in renal allograft recipients treated with intravenous erythromycin. 1993 Arch. Intern. Med. pmid:8466379
Sabbah A [Teldane update. Interview with Dr. Alfred Sabbah, chief of the immuno-allergology laboratory of the C.H.U. d'Angers. Interview by Dr. Pierre Ceddaha]. 1993 Allerg Immunol (Paris) pmid:8466639
Magat AH et al. Double-blind randomized study comparing amoxicillin and erythromycin for the treatment of Chlamydia trachomatis in pregnancy. 1993 Obstet Gynecol pmid:8469466
Weber FH et al. Erythromycin: a motilin agonist and gastrointestinal prokinetic agent. 1993 Am. J. Gastroenterol. pmid:8470625
Smith GR and Thornton EA Effect of disturbance of the gastrointestinal microflora on the faecal excretion of Fusobacterium necrophorum biovar A. 1993 Epidemiol. Infect. pmid:8472777
Garlaschi ML et al. Antimicrobial resistance among clinical isolates of Haemophilus influenzae in northern Italy. Collaborative Study on Pediatric Infectious Diseases. 1993 Eur. J. Epidemiol. pmid:8472803
Gannon H Ureaplasma urealyticum and its role in neonatal lung disease. 1993 Neonatal Netw pmid:8474408
Husfeldt P et al. Antibiotic treatment of sinusitis in general practice. A double-blind study comparing ofloxacin and erythromycin. 1993 Eur Arch Otorhinolaryngol pmid:8476582
Endou K et al. Implication of cohesive binding of a macrolide antibiotic, rokitamycin, to ribosomes from Staphylococcus aureus. 1993 J. Antibiot. pmid:8478265
Ruggiero G et al. Clinical efficacy of dirithromycin versus miocamycin in tonsillopharyngitis. 1993 J. Antimicrob. Chemother. pmid:8478300
Jacobson K Clinical efficacy of dirithromycin in pneumonia. 1993 J. Antimicrob. Chemother. pmid:8478303
Sides GD Clinical efficacy of dirithromycin in acute exacerbations of chronic bronchitis. 1993 J. Antimicrob. Chemother. pmid:8478304
Gaillat J A multicentre study comparing the safety and efficacy of dirithromycin with erythromycin in the treatment of bronchitis. 1993 J. Antimicrob. Chemother. pmid:8478305
Pozzi E Clinical efficacy of dirithromycin versus miocamycin in the treatment of acute bronchitis or acute exacerbations of chronic bronchitis. 1993 J. Antimicrob. Chemother. pmid:8478306
Derriennic M and Escande JP Dirithromycin in the treatment of skin and skin structure infections. 1993 J. Antimicrob. Chemother. pmid:8478307
Varanese L Pharmacokinetics and safety of dirithromycin in the elderly. 1993 J. Antimicrob. Chemother. pmid:8478308
Sides GD and Conforti PM Safety profile of dirithromycin. 1993 J. Antimicrob. Chemother. pmid:8478309
Barry AL et al. Dirithromycin disc susceptibility tests: interpretative criteria and quality control parameters. 1993 J. Antimicrob. Chemother. pmid:8478310
Bauernfeind A In-vitro activity of dirithromycin in comparison with other new and established macrolides. 1993 J. Antimicrob. Chemother. pmid:8478311
Labro MT et al. Modulation of human polymorphonuclear neutrophil function by macrolides: preliminary data concerning dirithromycin. 1993 J. Antimicrob. Chemother. pmid:8478312
Sides GD et al. Pharmacokinetics of dirithromycin. 1993 J. Antimicrob. Chemother. pmid:8478313
Bergogne-Bérézin E Tissue distribution of dirithromycin: comparison with erythromycin. 1993 J. Antimicrob. Chemother. pmid:8478314
Derriennic M et al. Dirithromycin in the treatment of streptococcal pharyngitis. 1993 J. Antimicrob. Chemother. pmid:8478315
Müller O and Wettich K Clinical efficacy of dirithromycin in pharyngitis and tonsillitis. 1993 J. Antimicrob. Chemother. pmid:8478316
Derby LE et al. Erythromycin-associated cholestatic hepatitis. 1993 Med. J. Aust. pmid:8479375
Kawamura O et al. Effect of erythromycin on interdigestive gastrointestinal contractile activity and plasma motilin concentration in humans. 1993 Dig. Dis. Sci. pmid:8482186
Ohtawa M et al. Mechanism of gastroprokinetic effect of EM523, an erythromycin derivative, in dogs. 1993 Gastroenterology pmid:8482446
Orr PH et al. Randomized placebo-controlled trials of antibiotics for acute bronchitis: a critical review of the literature. 1993 J Fam Pract pmid:8482934
Gustafsson BE et al. Prolonged induction of germfree bile acid pattern in conventional rats by antibiotics. 1977 Acta Med Scand pmid:848350
Rathore MH and Jenkins SG Group A beta-hemolytic Streptococcus: issue of resistance. 1993 Pediatr. Infect. Dis. J. pmid:8483636
Doménech J et al. [Evaluation of the possible ototoxicity of josamycin by high frequency audiometry]. 1993 An Otorrinolaringol Ibero Am pmid:8484488
Savolainen S et al. Peritonsillar abscess. Clinical and microbiologic aspects and treatment regimens. 1993 Arch. Otolaryngol. Head Neck Surg. pmid:8484941
Soriano F and Fernández-Roblas R High rates of erythromycin-resistant Streptococcus pneumoniae among penicillin-resistant strains. 1993 J. Antimicrob. Chemother. pmid:8486579
Grøndahl TO and Langmoen IA Epileptogenic effect of antibiotic drugs. 1993 J. Neurosurg. pmid:8487076
Piras G et al. Cloning and sequencing of the low-affinity penicillin-binding protein 3r-encoding gene of Enterococcus hirae S185: modular design and structural organization of the protein. 1993 J. Bacteriol. pmid:8491705
Tateda K et al. Effects of sub-MICs of erythromycin and other macrolide antibiotics on serum sensitivity of Pseudomonas aeruginosa. 1993 Antimicrob. Agents Chemother. pmid:8494362
Tankovic J et al. Antimicrobial susceptibility of Pediococcus spp. and genetic basis of macrolide resistance in Pediococcus acidilactici HM3020. 1993 Antimicrob. Agents Chemother. pmid:8494376
Foweraker JE et al. Ecology of Haemophilus influenzae and Haemophilus parainfluenzae in sputum and saliva and effects of antibiotics on their distribution in patients with lower respiratory tract infections. 1993 Antimicrob. Agents Chemother. pmid:8494378
Edelstein PH and Edelstein MA In vitro activity of RP 74501-RP 74502, a novel streptogramin antimicrobial mixture, against clinical isolates of Legionella species. 1993 Antimicrob. Agents Chemother. pmid:8494390
Tredaniel J et al. Diffuse panbronchiolitis: efficacy of low-dose erythromycin. 1993 Respir Med pmid:8497706
Prather CM et al. Gastric axial forces in experimentally delayed and accelerated gastric emptying. 1993 Am. J. Physiol. pmid:8498519
Iino Y et al. Erythromycin therapy for otitis media with effusion in sinobronchial syndrome. 1993 Arch. Otolaryngol. Head Neck Surg. pmid:8499096
Levison ME et al. In vitro activity and clinical efficacy of clindamycin in the treatment of infections due to anaerobic bacteria. 1977 J. Infect. Dis. pmid:850091
Watanabe Y et al. Chemical modification of erythromycins. IX. Selective methylation at the C-6 hydroxyl group of erythromycin A oxime derivatives and preparation of clarithromycin. 1993 J. Antibiot. pmid:8501007