erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Endocarditis, Bacterial D004697 5 associated lipids
Endocarditis, Subacute Bacterial D004698 1 associated lipids
Endometritis D004716 6 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Epidermitis, Exudative, of Swine D004818 1 associated lipids
Epilepsy D004827 35 associated lipids
Ergotism D004881 4 associated lipids
Erysipelas D004886 1 associated lipids
Erythema Multiforme D004892 3 associated lipids
Erythema Nodosum D004893 5 associated lipids
Erythrasma D004894 1 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Eye Diseases D005128 12 associated lipids
Factor X Deficiency D005171 2 associated lipids
Fecal Incontinence D005242 1 associated lipids
Femoral Fractures D005264 7 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Fever D005334 35 associated lipids
Fever of Unknown Origin D005335 3 associated lipids
Focal Infection, Dental D005491 1 associated lipids
Folliculitis D005499 7 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Foot Diseases D005534 4 associated lipids
Fractures, Open D005597 3 associated lipids
Furunculosis D005667 2 associated lipids
Gangrene D005734 3 associated lipids
Gardner Syndrome D005736 2 associated lipids
Gas Gangrene D005738 1 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Tourette Syndrome D005879 3 associated lipids
Glomerulonephritis D005921 35 associated lipids
Gonorrhea D006069 7 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Haemophilus Infections D006192 3 associated lipids
Hand Dermatoses D006229 5 associated lipids
Hearing Disorders D006311 10 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Hearing Loss, Functional D006315 2 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Heart Block D006327 3 associated lipids
Heart Diseases D006331 8 associated lipids
Cardiomegaly D006332 31 associated lipids
Heart Failure D006333 36 associated lipids
Heart Murmurs D006337 1 associated lipids
Hematemesis D006396 1 associated lipids
Hematuria D006417 13 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Hemolysis D006461 131 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Herpes Genitalis D006558 2 associated lipids
Herpes Zoster Ophthalmicus D006563 2 associated lipids
HIV Seropositivity D006679 15 associated lipids
Hoarseness D006685 2 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Hypersplenism D006971 3 associated lipids
Hypertension D006973 115 associated lipids
Hypotension D007022 41 associated lipids
Hypothermia D007035 19 associated lipids
Hypoventilation D007040 2 associated lipids
Impetigo D007169 3 associated lipids
Inappropriate ADH Syndrome D007177 4 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Inflammation D007249 119 associated lipids
Intestinal Atresia D007409 3 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Intraoperative Complications D007431 5 associated lipids
Ischemia D007511 18 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Jejunal Diseases D007579 3 associated lipids
Keratoconjunctivitis D007637 3 associated lipids
Keratoderma, Palmoplantar D007645 1 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Labyrinth Diseases D007759 3 associated lipids
Lacrimal Duct Obstruction D007767 1 associated lipids
Laryngitis D007827 5 associated lipids
Legionellosis D007876 3 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Leishmaniasis D007896 19 associated lipids
Leprosy D007918 8 associated lipids
Leukemia D007938 74 associated lipids
Leukemia P388 D007941 43 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Lipidoses D008064 7 associated lipids
Listeriosis D008088 12 associated lipids
Liver Abscess D008100 6 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Huang M et al. Single nucleotide polymorphism of CYP3A4 intron 2 and its influence on CYP3A4 mRNA expression and liver enzymatic activity in human liver. 2015 J. Huazhong Univ. Sci. Technol. Med. Sci. pmid:26223917
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Takagi M et al. Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. 2015 Drug Metab. Pharmacokinet. pmid:26195223
Aydin S et al. Development of antibiotic resistance genes in microbial communities during long-term operation of anaerobic reactors in the treatment of pharmaceutical wastewater. 2015 Water Res. pmid:26188597
Gaudreau C et al. Long-Lasting Outbreak of Erythromycin- and Ciprofloxacin-Resistant Campylobacter jejuni Subspecies jejuni From 2003 to 2013 in Men Who Have Sex With Men, Quebec, Canada. 2015 Clin. Infect. Dis. pmid:26187024
Dayie NT et al. Multidrug-Resistant Streptococcus pneumoniae Isolates from Healthy Ghanaian Preschool Children. 2015 Microb. Drug Resist. pmid:26172078
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Piccinelli G et al. Characterization and antibiotic susceptibility of Streptococcus agalactiae isolates causing urinary tract infections. 2015 Infect. Genet. Evol. pmid:26144658
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Høye S An extraordinary tale of an ordinary case. 2015 Tidsskr. Nor. Laegeforen. pmid:26130550
Fayed B et al. Multiplexed integrating plasmids for engineering of the erythromycin gene cluster for expression in Streptomyces spp. and combinatorial biosynthesis. 2015 Appl. Environ. Microbiol. pmid:26431970
Loose LM et al. Adolescent with respiratory impairments and short-lived fever. 2015 Tidsskr. Nor. Laegeforen. pmid:26130549
Dermota U et al. Survey of community-associated-methicillin-Resistant Staphylococcus aureus in Slovenia: identification of community-associated and livestock-associated clones. 2015 Int. J. Med. Microbiol. pmid:26055648
Drouet M et al. Endothelial Cell Toxicity of Vancomycin Infusion Combined with Other Antibiotics. 2015 Antimicrob. Agents Chemother. pmid:26055373
Reeves M et al. Acute colonic pseudo-obstruction in pregnancy. 2015 ANZ J Surg pmid:26044983
Vlakh EG et al. Preparation and characterization of macroporous monoliths imprinted with erythromycin. 2015 J Sep Sci pmid:26033867
Wang L et al. Changes in diversity of cultured bacteria resistant to erythromycin and tetracycline in swine manure during simulated composting and lagoon storage. 2015 Lett. Appl. Microbiol. pmid:26031793
Wang Z et al. MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation. 2015 PLoS ONE pmid:25706647
Yoon IA et al. Clinical significance of serotype V among infants with invasive group B streptococcal infections in South Korea. 2015 Int. J. Infect. Dis. pmid:26026823
Gherardi G et al. Decline in macrolide resistance rates among Streptococcus pyogenes causing pharyngitis in children isolated in Italy. 2015 Eur. J. Clin. Microbiol. Infect. Dis. pmid:26024763
Reveiz L and Cardona AF Antibiotics for acute laryngitis in adults. 2015 Cochrane Database Syst Rev pmid:26002823
Pesola AK et al. Clindamycin resistant emm33 Streptococcus pyogenes emerged among invasive infections in Helsinki metropolitan area, Finland, 2012 to 2013. 2015 Euro Surveill. pmid:25990232
Sun XJ et al. Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-δ/Akt pathway and increasing GR expression. 2015 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:25957293
Guo MT et al. Insights into the amplification of bacterial resistance to erythromycin in activated sludge. 2015 Chemosphere pmid:25957255
Kasai A et al. Prevalence and molecular analysis of macrolide-resistant Moraxella catarrhalis clinical isolates in Japan, following emergence of the highly macrolide-resistant strain NSH1 in 2011. 2015 J. Med. Microbiol. pmid:25934551
Melkumyan AR et al. Effects of antibiotic treatment on the lactobacillus composition of vaginal microbiota. 2015 Bull. Exp. Biol. Med. pmid:25894774
Romaniszyn D et al. Epidemiology, antibiotic consumption and molecular characterisation of Staphylococcus aureus infections--data from the Polish Neonatology Surveillance Network, 2009-2012. 2015 BMC Infect. Dis. pmid:25888217
Park JY et al. Construction of a shuttle vector based on the small cryptic plasmid pJY33 from Weissella cibaria 33. 2015 Plasmid pmid:25882072
Jakubů V et al. Minimum inhibitory concentrations of erythromycin and other antibiotics for Czech strains of Bordetella pertussis. 2015 Epidemiol Mikrobiol Imunol pmid:25872990
Koutsogiannidis CP et al. Decreased DNA Disruption in the Porcine Neocortex with Erythromycin Preconditioning during Prolonged Hypothermic Circulatory Arrest: Evidence for Neuroprotection. 2015 J Card Surg pmid:25858150
Kovač J et al. Antibiotic resistance modulation and modes of action of (-)-α-pinene in Campylobacter jejuni. 2015 PLoS ONE pmid:25830640
Abukar AA et al. Unusual cause of infective endocarditis in an elderly patient with a rare condition. 2015 BMJ Case Rep pmid:25820110
Hao H et al. Identification of Campylobacter jejuni and determination of point mutations associated with macrolide resistance using a multiplex TaqMan MGB real-time PCR. 2015 J. Appl. Microbiol. pmid:25766481
Nonaka L et al. Novel macrolide-resistance genes, mef(C) and mph(G), carried by plasmids from Vibrio and Photobacterium isolated from sediment and seawater of a coastal aquaculture site. 2015 Lett. Appl. Microbiol. pmid:25765542
Mills RO et al. Epidemiology of pneumococcal carriage in children under five years of age in Accra, Ghana. 2015 Infect Dis (Lond) pmid:25761718
Hersch M et al. Prokinetic drugs for gastric emptying in critically ill ventilated patients: Analysis through breath testing. 2015 J Crit Care pmid:25746849
Lee S et al. Functional analysis of Vibrio vulnificus RND efflux pumps homologous to Vibrio cholerae VexAB and VexCD, and to Escherichia coli AcrAB. 2015 J. Microbiol. pmid:25740377
Lysnyansky I et al. Decreased Susceptibility to Macrolide-Lincosamide in Mycoplasma synoviae Is Associated with Mutations in 23S Ribosomal RNA. 2015 Microb. Drug Resist. pmid:25734368
Abreu AC et al. Combinatorial Activity of Flavonoids with Antibiotics Against Drug-Resistant Staphylococcus aureus. 2015 Microb. Drug Resist. pmid:25734256
Ou H et al. Selective removal of erythromycin by magnetic imprinted polymers synthesized from chitosan-stabilized Pickering emulsion. 2015 J. Hazard. Mater. pmid:25704432
Ikebe T et al. Increased prevalence of group A streptococcus isolates in streptococcal toxic shock syndrome cases in Japan from 2010 to 2012. 2015 Epidemiol. Infect. pmid:25703404
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Luo H et al. Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. 2015 Avian Pathol. pmid:25690020
Sessa R et al. Effects of Mentha suaveolens essential oil on Chlamydia trachomatis. 2015 Biomed Res Int pmid:25685793
Shi JG et al. Predicting drug-drug interactions involving multiple mechanisms using physiologically based pharmacokinetic modeling: a case study with ruxolitinib. 2015 Clin. Pharmacol. Ther. pmid:25670523
Xu CW et al. First report of macrolide resistance gene erm(T) harbored by a novel small plasmid from Erysipelothrix rhusiopathiae. 2015 Antimicrob. Agents Chemother. pmid:25666150
Naquin A et al. Presence of antibiotic resistance genes in a sewage treatment plant in Thibodaux, Louisiana, USA. 2015 Bioresour. Technol. pmid:25662190
García-Mayor MA et al. Occurrence of erythromycin residues in sheep milk. Validation of an analytical method. 2015 Food Chem. Toxicol. pmid:25637760
van Eijk E et al. Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5. 2015 BMC Genomics pmid:25636331
Gao P et al. Impacts of coexisting antibiotics, antibacterial residues, and heavy metals on the occurrence of erythromycin resistance genes in urban wastewater. 2015 Appl. Microbiol. Biotechnol. pmid:25631280
Chan BC et al. Combating against methicillin-resistant Staphylococcus aureus - two fatty acids from Purslane (Portulaca oleracea L.) exhibit synergistic effects with erythromycin. 2015 J. Pharm. Pharmacol. pmid:25212982
Novak I and Kovač B Electronic structure of antibiotic erythromycin. 2015 Spectrochim Acta A Mol Biomol Spectrosc pmid:25528514
Ansari NN et al. A randomized clinical trial comparing pulsed ultrasound and erythromycin phonophoresis in the treatment of patients with chronic rhinosinusitis. 2015 Physiother Theory Pract pmid:25495769
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Harmer CJ et al. A type 2 A/C2 plasmid carrying the aacC4 apramycin resistance gene and the erm(42) erythromycin resistance gene recovered from two Salmonella enterica serovars. 2015 J. Antimicrob. Chemother. pmid:25468903
Wan J et al. Effect of erythromycin exposure on the growth, antioxidant system and photosynthesis of Microcystis flos-aquae. 2015 J. Hazard. Mater. pmid:25464321
Zhou Z et al. Macrolide-resistant Mycoplasma pneumoniae in adults in Zhejiang, China. 2015 Antimicrob. Agents Chemother. pmid:25451048
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Haxel BR et al. Controlled trial for long-term low-dose erythromycin after sinus surgery for chronic rhinosinusitis. 2015 Laryngoscope pmid:25425539
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Chen Y et al. The glucose RQ-feedback control leading to improved erythromycin production by a recombinant strain Saccharopolyspora erythraea ZL1004 and its scale-up to 372-m(3) fermenter. 2015 Bioprocess Biosyst Eng pmid:25042891
Llorca M et al. Identification of new transformation products during enzymatic treatment of tetracycline and erythromycin antibiotics at laboratory scale by an on-line turbulent flow liquid-chromatography coupled to a high resolution mass spectrometer LTQ-Orbitrap. 2015 Chemosphere pmid:24972175
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Mazur CS et al. P-glycoprotein inhibition by the agricultural pesticide propiconazole and its hydroxylated metabolites: Implications for pesticide-drug interactions. 2015 Toxicol. Lett. pmid:25268938
Song LY et al. Exploring Synergy between Classic Mutagens and Antibiotics To Examine Mechanisms of Synergy and Antibiotic Action. 2015 Antimicrob. Agents Chemother. pmid:26711761
Cochrane SA et al. Synthesis of Tridecaptin-Antibiotic Conjugates with in Vivo Activity against Gram-Negative Bacteria. 2015 J. Med. Chem. pmid:26636619
Liang Z et al. Structural Correspondence of the Oriented Attachment Growth Mechanism of Crystals of the Pharmaceutical Dirithromycin. 2015 Langmuir pmid:26632998
Shishkina AV et al. Modeling Interactions of Erythromycin Derivatives with Ribosomes. 2015 Biochemistry Mosc. pmid:26615442
Li X et al. Differential roles of the hemerythrin-like proteins of Mycobacterium smegmatis in hydrogen peroxide and erythromycin susceptibility. 2015 Sci Rep pmid:26607739
Cheng C et al. Ciprofloxacin plus erythromycin or ambroxol ameliorates endotracheal tube-associated Pseudomonas aeruginosa biofilms in a rat model. 2015 Pathol. Res. Pract. pmid:26601615
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Bérard A et al. Use of macrolides during pregnancy and the risk of birth defects: a population-based study. 2015 Pharmacoepidemiol Drug Saf pmid:26513406
Fedashchin A et al. Random transposon mutagenesis of the Saccharopolyspora erythraea genome reveals additional genes influencing erythromycin biosynthesis. 2015 FEMS Microbiol. Lett. pmid:26468041
Lu H et al. High frequency of the 23S rRNA A2058G mutation of Treponema pallidum in Shanghai is associated with a current strategy for the treatment of syphilis. 2015 Emerg Microbes Infect pmid:26038763
Yi X et al. Improved detection of multiple environmental antibiotics through an optimized sample extraction strategy in liquid chromatography-mass spectrometry analysis. 2015 Anal Bioanal Chem pmid:26449847
Ayazi P et al. Tick-borne Relapsing Fever in Children in the North-west of Iran, Qazvin. 2015 Prague Med Rep pmid:26445390
Yamaguchi M et al. Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche. 2015 Cell Rep pmid:26440893
Chazan B et al. Susceptibility of Group A Streptococcus to Antimicrobial Agents in Northern Israel: A Surveillance Study. 2015 Microb. Drug Resist. pmid:26430943
Kojima C et al. Distribution of Antimicrobial Resistance in Campylobacter Strains Isolated from Poultry at a Slaughterhouse and Supermarkets in Japan. 2015 Biocontrol Sci pmid:26412697
Hoffmann K et al. Prevalence and resistance patterns of commensal S. aureus in community-dwelling GP patients and socio-demographic associations. A cross-sectional study in the framework of the APRES-project in Austria. 2015 BMC Infect. Dis. pmid:25981559
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Dixit S and Park JH Enantioseparation of basic chiral drugs on a carbamoylated erythromycin-zirconia hybrid monolith using capillary electrochromatography. 2015 J Chromatogr A pmid:26372443
Michael-Kordatou I et al. Erythromycin oxidation and ERY-resistant Escherichia coli inactivation in urban wastewater by sulfate radical-based oxidation process under UV-C irradiation. 2015 Water Res. pmid:26360228
Ozbayram EG et al. Acute effects of various antibiotic combinations on acetoclastic methanogenic activity. 2015 Environ Sci Pollut Res Int pmid:25408075
Wang YL et al. Development of a Method for the Analysis of Multiclass Antibiotic Residues in Milk Using QuEChERS and Liquid Chromatography-Tandem Mass Spectrometry. 2015 Foodborne Pathog. Dis. pmid:26258263
Enayati M et al. Virulence and antimicrobial resistance of Enterococcus faecium isolated from water samples. 2015 Lett. Appl. Microbiol. pmid:26249819
Peyre L et al. High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical's bio-activation with regards hepatotoxicity. 2015 Toxicol In Vitro pmid:26239606
Aydın S et al. The joint acute effect of tetracycline, erythromycin and sulfamethoxazole on acetoclastic methanogens. 2015 Water Sci. Technol. pmid:25909721
Banik A et al. Inducible and constitutive clindamycin resistance in Staphylococcus aureus in a northeastern Indian tertiary care hospital. 2015 J Infect Dev Ctries pmid:26230122
Wang Z et al. Direct Detection of Erythromycin-Resistant Bordetella pertussis in Clinical Specimens by PCR. 2015 J. Clin. Microbiol. pmid:26224847
Olivieri R et al. Evolution of macrolide resistance in Streptococcus pyogenes over 14 years in an area of central Italy. 2015 J. Med. Microbiol. pmid:26224594