erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gupta AK et al. | A randomized, double-blind, multicenter, parallel group study to compare relative efficacies of the topical gels 3% erythromycin/5% benzoyl peroxide and 0.025% tretinoin/erythromycin 4% in the treatment of moderate acne vulgaris of the face. | 2003 Jan-Feb | J Cutan Med Surg | pmid:12362264 |
| Tsutsumi K et al. | The effect of erythromycin and clarithromycin on the pharmacokinetics of intravenous digoxin in healthy volunteers. | 2002 | J Clin Pharmacol | pmid:12362931 |
| Schmitz FJ et al. | Molecular analysis of constitutively expressed erm(C) genes selected in vitro by incubation in the presence of the noninducers quinupristin, telithromycin, or ABT-773. | 2002 | Microb. Drug Resist. | pmid:12363005 |
| Gonorrhea--recommended treatment schecules, 1974. | 1975 | Am Fam Physician | pmid:123699 | |
| Paladino JA et al. | Cost-effectiveness of IV-to-oral switch therapy: azithromycin vs cefuroxime with or without erythromycin for the treatment of community-acquired pneumonia. | 2002 | Chest | pmid:12377852 |
| Tsai SC et al. | Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases. | 2002 | Biochemistry | pmid:12379102 |
| Hauben M and Amsden GW | The association of erythromycin and infantile hypertrophic pyloric stenosis: causal or coincidental? | 2002 | Drug Saf | pmid:12381214 |
| Steinmetz WE et al. | The structure of erythromycin enol ether as a model for its activity as a motilide. | 2002 | J. Med. Chem. | pmid:12383015 |
| Bartley GB and Messenger MM | Outcome of tarsoconjunctival flap dehiscence after eyelid reconstruction. | 2002 | Am. J. Ophthalmol. | pmid:12383835 |
| Terekhova D et al. | Erythromycin resistance in Borrelia burgdorferi. | 2002 | Antimicrob. Agents Chemother. | pmid:12384380 |
| Stadler C and Teuber M | The macrolide efflux genetic assembly of Streptococcus pneumoniae is present in erythromycin-resistant Streptococcus salivarius. | 2002 | Antimicrob. Agents Chemother. | pmid:12384396 |
| Peng QZ et al. | [The construction of shuttle vectors of Brevibacillus brevis-Escherichia coli]. | 2002 | Sheng Wu Gong Cheng Xue Bao | pmid:12385239 |
| Thadepalli H et al. | Comparison of telithromycin, a new ketolide, with erythromycin and clarithromycin for the treatment of Haemophilus influenzae pneumonia in suckling, middle aged and senescent mice. | 2002 | Int. J. Antimicrob. Agents | pmid:12385696 |
| Gunics G et al. | Interaction between 3,5-diacetyl-1,4-dihydropyridines and ampicillin, and erythromycin on different E. coli strains. | 2002 | Int. J. Antimicrob. Agents | pmid:12385704 |
| Hayney MS and Buck JM | Effect of age and degree of immune activation on cytochrome P450 3A4 activity after influenza immunization. | 2002 | Pharmacotherapy | pmid:12389874 |
| Bicciato S et al. | Fermentation diagnosis by multivariate statistical analysis. | 2002 Jul-Dec | Appl. Biochem. Biotechnol. | pmid:12396110 |
| Gloor M et al. | Inhibition of lipase activity in antibiotic-resistant propionibacterium acnes strains. | 2002 | Dermatology (Basel) | pmid:12399674 |
| Tetracyclines for acne. | 1975 | Med Lett Drugs Ther | pmid:124010 | |
| Toudic F et al. | [Concomitant pulmonary nocardiosis and Hodgkin's disease: importance of long-term treatment]. | 2002 | Rev Pneumol Clin | pmid:12407289 |
| Ito I et al. | Hot spring bath and Legionella pneumonia: an association confirmed by genomic identification. | 2002 | Intern. Med. | pmid:12413010 |
| Calvinho LF et al. | [Antimicrobial sensitivity of coagulase-positive staphylococcal strains isolated from bovine mastitis in the central dairy catchment area of Argentina ]. | 2002 Jul-Sep | Rev. Argent. Microbiol. | pmid:12415901 |
| Rao SN et al. | Rectal botryomycosis mimicking carcinoma. | 2002 Sep-Oct | Indian J Gastroenterol | pmid:12416756 |
| Kubo JI et al. | Pharmacokinetic evaluation of high pulmonary disposition of clarithromycin after systemic administration. | 2002 | Xenobiotica | pmid:12419017 |
| Levaditi JC et al. | [Incidence and seasonal variations of bovine cerebral listeriosis observed in France during a survey on rabies]. | 1975 Jan-Feb | Bull Soc Pathol Exot Filiales | pmid:1242117 |
| Fujimura M et al. | Addition of a 2-month low-dose course of levofloxacin to long-term erythromycin therapy in sinobronchial syndrome. | 2002 | Respirology | pmid:12421239 |
| Gray IR | The choice of antibiotic for treating infective endocarditis. | 1975 | Q. J. Med. | pmid:1242238 |
| Guha A et al. | Effect of outer-membrane permeabilizers on the activity of antibiotics and plant extracts against Pseudomonas aeruginosa. | 2002 | Folia Microbiol. (Praha) | pmid:12422514 |
| Cummins CL et al. | Sex-related differences in the clearance of cytochrome P450 3A4 substrates may be caused by P-glycoprotein. | 2002 | Clin. Pharmacol. Ther. | pmid:12426511 |
| Paine MF et al. | Cytochrome P450 3A4 and P-glycoprotein mediate the interaction between an oral erythromycin breath test and rifampin. | 2002 | Clin. Pharmacol. Ther. | pmid:12426516 |
| Weir E | Resurgence of Bordetella pertussis infection. | 2002 | CMAJ | pmid:12427707 |
| Koenig JB et al. | Binding of radiolabeled porcine motilin and erythromycin lactobionate to smooth muscle membranes in various segments of the equine gastrointestinal tract. | 2002 | Am. J. Vet. Res. | pmid:12428665 |
| Guévin C et al. | Down-regulation of hepatic cytochrome p450 in chronic renal failure: role of uremic mediators. | 2002 | Br. J. Pharmacol. | pmid:12429576 |
| Neuhauser MM et al. | In vitro bactericidal activity of ABT-773 versus four other agents against Streptococcus pneumoniae and Haemophilus influenzae. | 2002 | Int. J. Antimicrob. Agents | pmid:12431879 |
| Gonorrhea. Recommended treatment schedules--1974. | 1975 | J. Pediatr. | pmid:124328 | |
| Pastor E et al. | [Macrolide consumption according to geographic areas in the province of Valladolid]. | 2002 | Enferm. Infecc. Microbiol. Clin. | pmid:12433351 |
| Grimprel E | [Pertussis]. | 2002 | Rev Prat | pmid:12434601 |
| Giovanetti E et al. | A novel efflux system in inducibly erythromycin-resistant strains of Streptococcus pyogenes. | 2002 | Antimicrob. Agents Chemother. | pmid:12435672 |
| Reeves AR et al. | Analysis of an 8.1-kb DNA fragment contiguous with the erythromycin gene cluster of Saccharopolyspora erythraea in the eryCI-flanking region. | 2002 | Antimicrob. Agents Chemother. | pmid:12435693 |
| Dicuonzo G et al. | Erythromycin-resistant pharyngeal isolates of Streptococcus pyogenes recovered in Italy. | 2002 | Antimicrob. Agents Chemother. | pmid:12435707 |
| Murata T et al. | The substrate specificity of tripartite efflux systems of Pseudomonas aeruginosa is determined by the RND component. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12437977 |
| Tsuji K and Robertson JH | Gas-liquid chromatography of antibiotics. | 1975 | Meth. Enzymol. | pmid:124391 |
| Hwang YH et al. | Simultaneous determination of various macrolides by liquid chromatography/mass spectrometry. | 2002 | J. Vet. Sci. | pmid:12441679 |
| Ewig S et al. | [Diagnosis and treatment of legionella pneumonia]. | 2002 | Pneumologie | pmid:12442211 |
| Robertson GT et al. | Vancomycin tolerance induced by erythromycin but not by loss of vncRS, vex3, or pep27 function in Streptococcus pneumoniae. | 2002 | J. Bacteriol. | pmid:12446649 |
| Owens RA and Bruening G | The pattern of amino acid incorporation into two cowpea mosaic virus proteins in the presence of ribosome-specific protein synthesis inhibitors. | 1975 | Virology | pmid:124497 |
| Philipson A et al. | Erythromycin and clindamycin absorption and elimination in pregnant women. | 1976 | Clin. Pharmacol. Ther. | pmid:1245094 |
| Son R et al. | Conjugal transfer of plasmids and antibiotic resistance among Escherichia coli isolated from animals in a rural area in Sarawak (Malaysia). | 1997 | J. Appl. Microbiol. | pmid:12452600 |
| Adam W et al. | Ene reaction of singlet oxygen, triazolinedione, and nitrosoarene with chiral deuterium-labeled allylic alcohols: the interdependence of diastereoselectivity and regioselectivity discloses mechanistic insights into the hydroxy-group directivity. | 2002 | J. Am. Chem. Soc. | pmid:12452715 |
| Smolianskaia AZ et al. | [Transduction of drug resistance in clinical strains of staphylococci]. | 1975 | Antibiotiki | pmid:124548 |
| Champney WS | Bacterial ribosomal subunit synthesis: a novel antibiotic target. | 2001 | Curr Drug Targets Infect Disord | pmid:12455231 |
| Zhong P and Shortridge V | The emerging new generation of antibiotic: ketolides. | 2001 | Curr Drug Targets Infect Disord | pmid:12455409 |
| Pablo GM and Fulton JE | Sebum: analysis by infrared spectroscopy. II. The suppression of fatty acids by systemically administered antibiotics. | 1975 | Arch Dermatol | pmid:124557 |
| Kealey JT | Creating polyketide diversity through genetic engineering. | 2003 | Front. Biosci. | pmid:12456305 |
| Kurokawa N et al. | Increasing ofloxacin resistance of bacterial flora from conjunctival sac of preoperative ophthalmic patients in Japan. | 2002 Sep-Oct | Jpn. J. Ophthalmol. | pmid:12457921 |
| Akata F et al. | Resistance to macrolides in Group A streptococci from the European section of Turkey: genetic and phenotypic characterization. | 2002 | Int. J. Antimicrob. Agents | pmid:12458142 |
| Hamilton-Miller JM and Shah S | Activity of ketolide ABT-773 (cethromycin) against erythromycin-resistant Streptococcus pneumoniae: correlation with extended MLSK phenotypes. | 2002 | J. Antimicrob. Chemother. | pmid:12461012 |
| Amador M et al. | Stereodivergent approach to beta-hydroxy alpha-amino acids from C(2)-symmetrical alk-2-yne-1,4-diols. | 2002 | Org. Lett. | pmid:12465925 |
| Nyirady J et al. | The stability of tretinoin in tretinoin gel microsphere 0.1%. | 2002 | Cutis | pmid:12469785 |
| LeVeen HH et al. | Effects of prophylactic antibiotics on colonic healing. | 1976 | Am. J. Surg. | pmid:1247153 |
| Cooper SM et al. | Linear IgA disease: successful treatment with erythromycin. | 2002 | Clin. Exp. Dermatol. | pmid:12472545 |
| Li Y et al. | Fourteen-membered ring macrolides inhibit vascular cell adhesion molecule 1 messenger RNA induction and leukocyte migration: role in preventing lung injury and fibrosis in bleomycin-challenged mice. | 2002 | Chest | pmid:12475858 |
| Yazgi H et al. | [Erythromycin resistance of group A beta-hemolytic streptococci isolated from patients with upper respiratory tract infections]. | 2002 | Mikrobiyol Bul | pmid:12476761 |
| Fernet CS et al. | The mitochondrial genome can be altered or lost without lethal effect in the petite-negative yeast Debaryomyces (Schwanniomyces) occidentalis. | 2002 | Curr. Genet. | pmid:12478388 |
| DÃaz-MejÃa JJ et al. | Antibiotic resistance in oral commensal streptococci from healthy Mexicans and Cubans: resistance prevalence does not mirror antibiotic usage. | 2002 | FEMS Microbiol. Lett. | pmid:12480100 |
| Khan WA et al. | Comparison of single-dose azithromycin and 12-dose, 3-day erythromycin for childhood cholera: a randomised, double-blind trial. | 2002 | Lancet | pmid:12480424 |
| Santos-Juanes J et al. | Cutaneous granulomas caused by corynebacterium minutissimum in an HIV-infected man. | 2002 | J Eur Acad Dermatol Venereol | pmid:12482058 |
| Demachy MC | [Lower respiratory tract infections in the child. The microbiologist's point of view]. | 2002 | Presse Med | pmid:12489327 |
| Olivier-Weil C | [Lower respiratory tract infections in the child. The clinician's point of view]. | 2002 | Presse Med | pmid:12489328 |
| Ohara T et al. | Novel antibacterial macrolides: synthesis of 15-membered diolides. | 2002 | J. Org. Chem. | pmid:12492314 |
| Wanwimolruk S et al. | Is quinine a suitable probe to assess the hepatic drug-metabolizing enzyme CYP3A4? | 2002 | Br J Clin Pharmacol | pmid:12492613 |
| Stylianopoulos A et al. | Is penicillin and/or erythromycin resistance present in clinical isolates of group B streptococcus in our community? | 2002 | Aust N Z J Obstet Gynaecol | pmid:12495105 |
| Nachamkin I et al. | Increasing fluoroquinolone resistance in Campylobacter jejuni, Pennsylvania, USA,1982-2001. | 2002 | Emerging Infect. Dis. | pmid:12498672 |
| Waites KB et al. | In vitro activities of ABT-773 and other antimicrobials against human mycoplasmas. | 2003 | Antimicrob. Agents Chemother. | pmid:12499166 |
| Rautelin H et al. | Antimicrobial susceptibilities of Campylobacter strains isolated from Finnish subjects infected domestically or from those infected abroad. | 2003 | Antimicrob. Agents Chemother. | pmid:12499176 |
| Mason EO et al. | In vitro activities of cethromycin (ABT-773), a new ketolide, against Streptococcus pneumoniae strains that are not susceptible to penicillin or macrolides. | 2003 | Antimicrob. Agents Chemother. | pmid:12499186 |
| Braga PC et al. | Flow cytometric assessment of susceptibilities of Streptococcus pyogenes to erythromycin and rokitamycin. | 2003 | Antimicrob. Agents Chemother. | pmid:12499226 |
| Raoult D | Use of macrolides for Q fever. | 2003 | Antimicrob. Agents Chemother. | pmid:12499237 |
| Beale GH and Knowles JK | Interspecies transfer of mitochondria in Paramecium aurelia. | 1976 | Mol. Gen. Genet. | pmid:1250220 |
| Besombes S et al. | Molecular modeling of syringyl and p-hydroxyphenyl beta-O-4 dimers. Comparative study of the computed and experimental conformational properties of lignin beta-O-4 model compounds. | 2003 | J. Agric. Food Chem. | pmid:12502382 |
| Asharaf M and Letha S | Cutaneous bacillary angiomatosis. | 2002 | Indian J Pediatr | pmid:12503674 |
| Kenyon S and Taylor DJ | The effect of the publication of a major clinical trial in a high impact journal on clinical practise: the ORACLE Trial experience. | 2002 | BJOG | pmid:12504968 |
| Asakawa A et al. | Ob/ob mice as a model of delayed gastric emptying. | 2003 Jan-Feb | J. Diabetes Complicat. | pmid:12505753 |
| Moro ML et al. | [Antibiotic microbial resistance surveillance in invasive infections caused by Streptococcus pneumoniae and Staphylococcus aureus: the EARSS (European Antimicrobial Resistance Surveillance System) project in Italy (April 1999-April 2000)]. | 2002 Sep-Oct | Ann Ig | pmid:12508445 |
| Lau WC et al. | Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: a new drug-drug interaction. | 2003 | Circulation | pmid:12515739 |
| Montanari MP et al. | Phenotypes and genotypes of erythromycin-resistant pneumococci in Italy. | 2003 | J. Clin. Microbiol. | pmid:12517885 |
| Lancashire WE and Griffiths DE | Studies on energy-linked reactions: isolation, characterisation and genetic analysis of trialkyl-tin-resistant mutants of Saccharomyces cerevisiae. | 1975 | Eur. J. Biochem. | pmid:125200 |
| Champney WS and Tober CL | Preferential inhibition of protein synthesis by ketolide antibiotics in Haemophilus influenzae cells. | 2003 | Curr. Microbiol. | pmid:12520364 |
| Buckingham SC et al. | Pneumonitis associated with Ureaplasma urealyticum in children with cancer. | 2003 | Clin. Infect. Dis. | pmid:12522757 |
| Butler JC et al. | Macrolide-resistant pneumococcal endocarditis and epidural abscess that develop during erythromycin therapy. | 2003 | Clin. Infect. Dis. | pmid:12522763 |
| Wilkinson PM | Clinical pharmacology of antibiotic therapy. | 1976 | Br J Anaesth | pmid:1252306 |
| Boivin MA et al. | Erythromycin accelerates gastric emptying in a dose-response manner in healthy subjects. | 2003 | Pharmacotherapy | pmid:12523456 |
| Borgen K et al. | Genetic linkage between erm(B) and vanA in Enterococcus hirae of poultry origin. | 2002 | Microb. Drug Resist. | pmid:12523634 |
| Kogan R et al. | Comparative randomized trial of azithromycin versus erythromycin and amoxicillin for treatment of community-acquired pneumonia in children. | 2003 | Pediatr. Pulmonol. | pmid:12526069 |
| Drury M | Letter: Otitis media. | 1976 | Br Med J | pmid:1252867 |
| Metlay JP | Tensions in antibiotic prescribing. | 2002 | LDI Issue Brief | pmid:12528744 |
| Booth AJ et al. | Modeling the performance of pilot-scale countercurrent chromatography: scale-up predictions and experimental verification of erythromycin separation. | 2003 | Biotechnol. Bioeng. | pmid:12529878 |
| Carr WG | Letter: Unusual reaction to erythromycin. | 1976 | Can Med Assoc J | pmid:1253027 |
| Herold DA | [Treatment of warts. An acne ointment helps, too]. | 2002 | MMW Fortschr Med | pmid:12532539 |
| Orlando R et al. | Effect of the CYP3A4 inhibitor erythromycin on the pharmacokinetics of lignocaine and its pharmacologically active metabolites in subjects with normal and impaired liver function. | 2003 | Br J Clin Pharmacol | pmid:12534644 |
| Becla E | The effect of erythromycin on the growth of Rickettsia prowazekii in the body louse (Pediculus humanus corporis L) and the tick (Ornithodoros moubata Murray). | 1976 | Chemotherapy | pmid:1253630 |