erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
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Authors | Title | Published | Journal | PubMed Link |
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Eckman MR et al. | Letter: Partial deafness after erythromycin. | 1975 | N. Engl. J. Med. | pmid:1113753 |
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Citron DM and Appleman MD | Comparative in vitro activities of ABT-773 against 362 clinical isolates of anaerobic bacteria. | 2001 | Antimicrob. Agents Chemother. | pmid:11120995 |
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Singh KV et al. | Disruption of an Enterococcus faecium species-specific gene, a homologue of acquired macrolide resistance genes of staphylococci, is associated with an increase in macrolide susceptibility. | 2001 | Antimicrob. Agents Chemother. | pmid:11120975 |
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Andrews JM et al. | The in vitro activity of ABT773, a new ketolide antimicrobial agent. | 2000 | J. Antimicrob. Chemother. | pmid:11102425 |
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Mikoc A et al. | Construction and characterization of a Streptomyces rimosus recA mutant: the RecA-deficient strain remains viable. | 2000 | Mol. Gen. Genet. | pmid:11085261 |
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Ishii T et al. | Improvement in bronchiolitis obliterans organizing pneumonia in a child after allogeneic bone marrow transplantation by a combination of oral prednisolone and low dose erythromycin. | 2000 | Bone Marrow Transplant. | pmid:11081394 |
Salvatore P et al. | A new vector for insertion of any DNA fragment into the chromosome of transformable Neisseriae. | 2000 | Plasmid | pmid:11078653 |
Putrament A et al. | Manganese mutagenesis in yeast. IV. The effects of magnesium, protein synthesis inhibitors and hydroxyurea on AntR induction in mitochondrial DNA. | 1975 | Mol. Gen. Genet. | pmid:1107804 |
Weisblum B et al. | Deoxyribonucleic acid sequence common to staphylococcal and streptococcal plasmids which specify erythromycin resistance. | 1979 | J. Bacteriol. | pmid:110774 |
Kuriyama T et al. | Bacteriologic features and antimicrobial susceptibility in isolates from orofacial odontogenic infections. | 2000 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod | pmid:11077383 |
Prueksaritanont T et al. | Simvastatin does not affect CYP3A activity, quantified by the erythromycin breath test and oral midazolam pharmacokinetics, in healthy male subjects. | 2000 | J Clin Pharmacol | pmid:11075313 |
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Riippi M et al. | Effect of compression force on the crystal properties of erythromycin acistrate tablets. | 2000 | Eur J Pharm Biopharm | pmid:11072193 |
Matsunaga H et al. | Manometric evidence of improved early gastric stasis by erythromycin after pylorus-preserving pancreatoduodenectomy. | 2000 | World J Surg | pmid:11071469 |
Patole SK et al. | Benefits of a standardised feeding regimen during a clinical trial in preterm neonates. | 2000 | Int. J. Clin. Pract. | pmid:11070566 |
Morikawa T et al. | Superoxide dismutase in alveolar macrophages from patients with diffuse panbronchiolitis. | 2000 | Respiration | pmid:11070461 |
Buschmann G and Duprée C | [Oral treatment of udder actinomycosis in swine]. | 1976 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:1106993 |
Kiso S et al. | Inhibitory effect of erythromycin on P-glycoprotein-mediated biliary excretion of doxorubicin in rats. | 2000 Sep-Oct | Anticancer Res. | pmid:11062690 |
Okamoto H et al. | Comparative in vitro activity of telithromycin (HMR 3647), three macrolides, amoxycillin, cefdinir and levofloxacin against gram-positive clinical isolates in Japan. | 2000 | J. Antimicrob. Chemother. | pmid:11062201 |
Kataja J et al. | Erythromycin resistance genes in group A streptococci of different geographical origins. The Macrolide Resistance Study Group. | 2000 | J. Antimicrob. Chemother. | pmid:11062199 |
Granizo JJ et al. | Streptococcus pneumoniae resistance to erythromycin and penicillin in relation to macrolide and beta-lactam consumption in Spain (1979-1997). | 2000 | J. Antimicrob. Chemother. | pmid:11062196 |
Lagrou K et al. | Subinhibitory concentrations of erythromycin reduce pneumococcal adherence to respiratory epithelial cells in vitro. | 2000 | J. Antimicrob. Chemother. | pmid:11062190 |