erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kawasaki S et al. | [Effects of a steroid and macrolide antibiotic on IL-8 production by neutrophils]. | 1997 | Jpn J Antibiot | pmid:9597446 |
| Mineshita M et al. | [Effect of macrolide antibiotics on actin polymerization reactions of neutrophils]. | 1997 | Jpn J Antibiot | pmid:9597447 |
| Sato K et al. | [Pyocyanine synthesis by Pseudomonas aeruginosa in chronic airway infection and the effect of erythromycin on its biological activity]. | 1997 | Jpn J Antibiot | pmid:9597453 |
| Ohara K et al. | [Effects of pretreatment by erythromycin or rokitamycin on aminoglycoside inactivating enzyme of Pseudomonas aeruginosa]. | 1997 | Jpn J Antibiot | pmid:9597454 |
| Kobayashi O et al. | [Actions of macrolide antibiotics on alginate production by Pseudomonas aeruginosa]. | 1997 | Jpn J Antibiot | pmid:9597455 |
| Kondo K et al. | [Quantitative evaluation of the inhibitory action of macrolide antibiotics on biofilm formation by Pseudomonas aeruginosa]. | 1997 | Jpn J Antibiot | pmid:9597456 |
| Kudo S | [Preliminary survey on DPB (diffuse panbronchitis) in Japan and a survey on the status of DPB in China]. | 1997 | Jpn J Antibiot | pmid:9597457 |
| Tei A et al. | [Effects and actions of EM (erythromycin), CAM (clarithromycin), and JM (josamycin) on IL-4 and IL-5 production by monocytes]. | 1997 | Jpn J Antibiot | pmid:9597458 |
| Hoshina S et al. | [C kinase activation and induction of HL 60 promyelocytic leukemia cell differentiation caused by roxithromycin]. | 1997 | Jpn J Antibiot | pmid:9597464 |
| Takada T et al. | [Study of specific mRNA expression by peripheral monocytes of patients with diffuse panbronchitis using cDNA representational difference analysis (RDA)]. | 1997 | Jpn J Antibiot | pmid:9597465 |
| Kaseta M et al. | [Study of therapeutic effects of macrolide antibiotics on patients with anti-HTLV-1 antibody positive DPB (diffuse panbronchitis)]. | 1997 | Jpn J Antibiot | pmid:9597466 |
| Miyashima S et al. | [Effects of erythromycin on a mouse hypersensitivity pneumonia model]. | 1997 | Jpn J Antibiot | pmid:9597469 |
| Nonaka M et al. | [Effects of macrolide antibiotics on fibroblasts]. | 1997 | Jpn J Antibiot | pmid:9597470 |
| Hori S et al. | [Effects of macrolide drugs on endogenous glucocorticoids]. | 1997 | Jpn J Antibiot | pmid:9597471 |
| Hikariyama T et al. | [Study of suppression of neutrophil functions and prevention of vascular endothelial injury by macrolide antibiotics]. | 1998 | Jpn J Antibiot | pmid:9597473 |
| Tamaoki J et al. | [Effects of macrolide antibiotics on iNOS gene expression and NO production by alveolar macrophages]. | 1998 | Jpn J Antibiot | pmid:9597474 |
| Takeda H et al. | [Bone absorption suppression by broad spectrum antibiotics]. | 1998 | Jpn J Antibiot | pmid:9597475 |
| Kawasaki S et al. | [Effects of a steroid and macrolide antibiotic on adhesion of neutrophils to the airway epithelial cells]. | 1998 | Jpn J Antibiot | pmid:9597483 |
| Nakada K et al. | [Therapeutic guideline for diffuse panbronchitis (draft). Subcommittee on Diffuse Lung Diseases, Research Committee on Respiratory Diseases Organized by the Ministry of Health and Welfare]. | 1998 | Jpn J Antibiot | pmid:9597494 |
| Shirai R et al. | [Evaluation of the duration of medication with erythromycin for treatment of diffuse panbronchitis--a comparison between interruption of medication and continued administration]. | 1998 | Jpn J Antibiot | pmid:9597496 |
| Kishi K et al. | [Study of efficacy of macrolide therapy applied to Kartagener's syndrome]. | 1998 | Jpn J Antibiot | pmid:9597497 |
| Miyazawa T et al. | [Mucous pathology and macrolide treatment of paranasal sinusitis in children]. | 1998 | Jpn J Antibiot | pmid:9597499 |
| Okura M et al. | [Multicenter study on clinical effects of a small dose of erythromycin on chronic lung disorders of premature infants--single blind comparison of treated and untreated groups. A committee for the Study of EM Therapy for Chronic Lung Diseases of Premature Infants]. | 1998 | Jpn J Antibiot | pmid:9597500 |
| Nishimura J et al. | [Effects of erythromycin on Pseudomonas aeruginosa pyocyanine-induced IL-8 production and its biological activity (the 2nd report)]. | 1998 | Jpn J Antibiot | pmid:9597503 |
| Abe S et al. | [Effect of macrolides on IL-8 gene expression by cultured airway epithelial cells]. | 1998 | Jpn J Antibiot | pmid:9597504 |
| Sugiyama Y et al. | [Changes in cytokine production by pulmonary alveolar macrophages collected from rats that have been treated with erythromycin for an extended period]. | 1998 | Jpn J Antibiot | pmid:9597506 |
| Yoshimine H et al. | [Inhibition of neutrophil-derived IL-8 production caused by EM (erythromycin) 201 derivative: modification of the activities by the 5-position desosamine side chain]. | 1998 | Jpn J Antibiot | pmid:9597508 |
| Kozeki S et al. | [Study on bacterial biofilm destruction by various antibacterial agents]. | 1998 | Jpn J Antibiot | pmid:9597510 |
| Nakada M et al. | [Inhibitory effects of macrolide antibiotics at low concentrations on vero toxin production by pathogenic E. coli O157]. | 1998 | Jpn J Antibiot | pmid:9597511 |
| Kyo S et al. | [Effects of macrolides on intracellular Ca2+ response by airway epithelium]. | 1998 | Jpn J Antibiot | pmid:9597513 |
| Tanabe O et al. | [Mechanism of erythromycin action on gene expression of airway epithelial cells]. | 1998 | Jpn J Antibiot | pmid:9597514 |
| Muranaka H et al. | [Superoxide radical scavenging activity of an erythromycin-iron complex (the second report)]. | 1998 | Jpn J Antibiot | pmid:9597516 |
| Ng P et al. | Diffuse panbronchiolitis: case report and review of the literature. | 1998 | Australas Radiol | pmid:9599832 |
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| Paesen J et al. | Study of the stability of erythromycin in a hydrophilic creme basis by liquid chromatography. | 1998 | J Pharm Biomed Anal | pmid:9608426 |
| Kudoh S | Erythromycin treatment in diffuse panbronchiolitis. | 1998 | Curr Opin Pulm Med | pmid:9612675 |
| Neubrand M and Sauerbruch T | Erythromycin, a motilin agonist, increases postprandial gallbladder emptying during therapy with ursodeoxycholic acid. | 1998 | Z Gastroenterol | pmid:9612923 |
| Gaisser S et al. | Analysis of eryBI, eryBIII and eryBVII from the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea. | 1998 | Mol. Gen. Genet. | pmid:9613575 |
| Mathis C and Malbert CH | Changes in pyloric resistance induced by erythromycin. | 1998 | Neurogastroenterol. Motil. | pmid:9614671 |
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| Krone LV | The importance of multiple antibiotic coverage for hospitalized patients when the community acquired pneumonia is Legionnaire's disease. | 1998 | WMJ | pmid:9617308 |
| Kudoh S et al. | Improvement of survival in patients with diffuse panbronchiolitis treated with low-dose erythromycin. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9620913 |
| Kruppa A et al. | Immediate reaction to roxithromycin and prick test cross-sensitization to erythromycin and clarithromycin. | 1998 | Dermatology (Basel) | pmid:9621142 |
| Widdowson CA and Klugman KP | Emergence of the M phenotype of erythromycin-resistant pneumococci in South Africa. | 1998 Apr-Jun | Emerging Infect. Dis. | pmid:9621199 |
| Rosato A et al. | A new ketolide, HMR 3004, active against streptococci inducibly resistant to erythromycin. | 1998 | Antimicrob. Agents Chemother. | pmid:9624482 |
| Muli F and Struthers JK | Use of a continuous-culture biofilm system to study the antimicrobial susceptibilities of Gardnerella vaginalis and Lactobacillus acidophilus. | 1998 | Antimicrob. Agents Chemother. | pmid:9624489 |
| Kataja J et al. | Different erythromycin resistance mechanisms in group C and group G streptococci. | 1998 | Antimicrob. Agents Chemother. | pmid:9624500 |