erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Jones TR et al. | Efficacy of an antibiotic mouthwash in contaminated head and neck surgery. | 1989 | Am. J. Surg. | pmid:2802036 |
Brass C et al. | The effect of metronidazole on the incidence of postoperative wound infection in elective colon surgery. | 1978 | Am. J. Surg. | pmid:341733 |
LeVeen HH et al. | Effects of prophylactic antibiotics on colonic healing. | 1976 | Am. J. Surg. | pmid:1247153 |
Carlson RG et al. | Erythromycin enhances delayed gastric emptying in dogs after Roux-Y antrectomy. | 1991 | Am. J. Surg. | pmid:1987856 |
Nissan A et al. | Direct inhibitory effect of erythromycin on human alimentary tract smooth muscle. | 2002 | Am. J. Surg. | pmid:11975929 |
Dillon ML and Bowling KA | Effect of antibiotics on wound and stool cultures. Comparison of intravenous terramycin with other antibiotics. | 1967 | Am. J. Surg. | pmid:5334435 |
Nakabayashi T et al. | Gastropyloric motor activity and the effects of erythromycin given orally after esophagectomy. | 2002 | Am. J. Surg. | pmid:11943134 |
COHN I and LONGACRE AB | Erythromycin and erythromycin-neomycin for intestinal antisepsis. | 1957 | Am. J. Surg. | pmid:13458603 |
Tzovaras G et al. | The effect of intravenous erythromycin on esophageal motility in healthy subjects. | 1996 | Am. J. Surg. | pmid:8615464 |
Gombert ME et al. | Cavitary Legionnaires' pneumonia: nosocomial infection in renal transplant recipients. | 1984 | Am. J. Surg. | pmid:6367506 |
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Fry DE | Colon preparation and surgical site infection. | 2011 | Am. J. Surg. | pmid:21429471 |
Weaver M et al. | Oral neomycin and erythromycin compared with single-dose systemic metronidazole and ceftriaxone prophylaxis in elective colorectal surgery. | 1986 | Am. J. Surg. | pmid:3083705 |
Baciewicz AM and Baciewicz FA | Cyclosporine pharmacokinetic drug interactions. | 1989 | Am. J. Surg. | pmid:2644865 |
EICHENWALD HF and SHINEFIELD HR | RATIONAL USE OF ANTIBIOTICS. | 1964 | Am. J. Surg. | pmid:14129331 |
Condon RE et al. | Oral neomycin and erythromycin compared with single-dose systemic metronidazole and ceftriaxone prophylaxis in elective colorectal surgery. | 1986 | Am. J. Surg. | pmid:3777340 |
Vanaudenaerde BM et al. | Macrolides inhibit IL17-induced IL8 and 8-isoprostane release from human airway smooth muscle cells. | 2007 | Am. J. Transplant. | pmid:17061983 |
JUNG RC et al. | Fumagillin and erythromycin in the treatment of amebiasis. | 1955 | Am. J. Trop. Med. Hyg. | pmid:13268803 |
MCHARDY G et al. | Erythromycin in amebiasis. | 1955 | Am. J. Trop. Med. Hyg. | pmid:13268804 |
NELSON TL et al. | Amebic hepatitis; laboratory findings and treatment with erythromycin. | 1955 | Am. J. Trop. Med. Hyg. | pmid:13259005 |
Hamel MJ et al. | Efficacy of trimethoprim-sulfamethoxazole compared with sulfadoxine-pyrimethamine plus erythromycin for the treatment of uncomplicated malaria in children with integrated management of childhood illness dual classifications of malaria and pneumonia. | 2005 | Am. J. Trop. Med. Hyg. | pmid:16172491 |
NOR EL-DIN G | Erythromycin in the treatment of amebiasis. | 1956 | Am. J. Trop. Med. Hyg. | pmid:13292653 |
Gingras BA and Jensen JB | Activity of azithromycin (CP-62,993) and erythromycin against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum in vitro. | 1992 | Am. J. Trop. Med. Hyg. | pmid:1326232 |
Robins-Browne RM et al. | Treatment of acute nonspecific gastroenteritis of infants and young children with erythromycin. | 1983 | Am. J. Trop. Med. Hyg. | pmid:6349401 |
WILMOT AJ et al. | Erythromycin in amebic liver abscess. | 1958 | Am. J. Trop. Med. Hyg. | pmid:13595213 |
ANDERSON HH et al. | Erythromycin stearate against systemic amebiasis in Colombia. | 1955 | Am. J. Trop. Med. Hyg. | pmid:13238724 |
VILLAREJOS VM | Treatment of amebiasis with erythromycin. | 1955 | Am. J. Trop. Med. Hyg. | pmid:13238725 |
Kelly DJ et al. | Rickettsia tsutsugamushi infection in cell culture: antibiotic susceptibility determined by flow cytometry. | 1995 | Am. J. Trop. Med. Hyg. | pmid:8561261 |
ANDERSON HH et al. | Antibiotic synergism in amebiasis. | 1954 | Am. J. Trop. Med. Hyg. | pmid:13138827 |
Hall KA et al. | Characterization of counterfeit artesunate antimalarial tablets from southeast Asia. | 2006 | Am. J. Trop. Med. Hyg. | pmid:17123969 |
Gingras BA and Jensen JB | Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. | 1993 | Am. J. Trop. Med. Hyg. | pmid:8394660 |
MCCOWEN MC et al. | The effects of erythromycin (ilotycin, lilly) against certain parasitic organisms. | 1953 | Am. J. Trop. Med. Hyg. | pmid:13040654 |
Crawford KA et al. | Efficacy of amoscanate against experimental schistosomal infections in monkeys. | 1983 | Am. J. Trop. Med. Hyg. | pmid:6625061 |
Perine PL and Teklu B | Antibiotic treatment of louse-borne relapsing fever in Ethiopia: a report of 377 cases. | 1983 | Am. J. Trop. Med. Hyg. | pmid:6625065 |
MARSHALL RT et al. | THE EFFECTS OF BLOOD AND NONFAT MILK CONSTITUTENTS ON DIFFUSION OF BACTERIAL INHIBITORS IN AGAR MEDIUMS. | 1964 | Am. J. Vet. Res. | pmid:14266843 |
PLASTRIDGE WN et al. | ANTIBIOTIC SENSITIVITY OF PHYSIOLOGIC GROUPS OF MICROAEROPHILIC VIBRIOS. | 1964 | Am. J. Vet. Res. | pmid:14266885 |
Clarke CR et al. | Response of Pasteurella haemolytica to erythromycin and dexamethasone in calves with established infection. | 1992 | Am. J. Vet. Res. | pmid:1524293 |
Burrows GE | Effects of experimentally induced Pasteurella haemolytica pneumonia on the pharmacokinetics of erythromycin in the calf. | 1985 | Am. J. Vet. Res. | pmid:4014829 |
Garner HE and Coles EH | Staphylococcus aureus of canine origin: bacteriophage typing and antibiotic sensitivity of cultures isolated from the nostril. | 1965 | Am. J. Vet. Res. | pmid:5882553 |
FLORESTANO HJ and BAHLER ME | Chemotherapeutic properties of erythromycin alone and in combination with sulfamerazine. | 1955 | Am. J. Vet. Res. | pmid:13228887 |
Nieto JE et al. | Use of an extracorporeal circuit to evaluate effects of intraluminal distention and decompression on the equine jejunum. | 2002 | Am. J. Vet. Res. | pmid:11843129 |
Palmer JE and Benson CE | Effect of treatment with erythromycin and rifampin during the acute stages of experimentally induced equine ehrlichial colitis in ponies. | 1992 | Am. J. Vet. Res. | pmid:1466503 |
Lakritz J et al. | Effects of prior feeding on pharmacokinetics and estimated bioavailability after oral administration of a single dose of microencapsulated erythromycin base in healthy foals. | 2000 | Am. J. Vet. Res. | pmid:10976728 |
Khan SA et al. | Characterization of erythromycin-resistant methylase genes from multiple antibiotic resistant Staphylococcus spp isolated from milk samples of lactating cows. | 2000 | Am. J. Vet. Res. | pmid:10976747 |
Koenig JB et al. | Use of multichannel electrointestinography for noninvasive assessment of myoelectrical activity in the cecum and large colon of horses. | 2008 | Am. J. Vet. Res. | pmid:18518649 |
Wittek T and Constable PD | Assessment of the effects of erythromycin, neostigmine, and metoclopramide on abomasal motility and emptying rate in calves. | 2005 | Am. J. Vet. Res. | pmid:15822601 |
Wilson RC et al. | Serum erythromycin concentration in sheep fed two diets. | 1984 | Am. J. Vet. Res. | pmid:6742574 |
DeGeeter MJ and Stahl GL | Sensitivity of Escherichia coli after exposure to lincomycin in vitro and in vivo. | 1976 | Am. J. Vet. Res. | pmid:776050 |
Kinoshita T et al. | Impact of age-related alteration of plasma alpha 1-acid glycoprotein concentration on erythromycin pharmacokinetics in pigs. | 1995 | Am. J. Vet. Res. | pmid:7771705 |