erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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He M et al. | Dynamics of serotype 14 Streptococcus pneumoniae population causing acute respiratory infections among children in China (1997-2012). | 2015 | BMC Infect. Dis. | pmid:26163293 |
Piccinelli G et al. | Characterization and antibiotic susceptibility of Streptococcus agalactiae isolates causing urinary tract infections. | 2015 | Infect. Genet. Evol. | pmid:26144658 |
Wang P et al. | Serotype distribution, antimicrobial resistance, and molecular characterization of invasive group B Streptococcus isolates recovered from Chinese neonates. | 2015 | Int. J. Infect. Dis. | pmid:26141418 |
Høye S | An extraordinary tale of an ordinary case. | 2015 | Tidsskr. Nor. Laegeforen. | pmid:26130550 |
Loose LM et al. | Adolescent with respiratory impairments and short-lived fever. | 2015 | Tidsskr. Nor. Laegeforen. | pmid:26130549 |
Liu J et al. | Preparation and characterization of erythromycin molecularly imprinted polymers based on distillation-precipitation polymerization. | 2015 | J Sep Sci | pmid:26118901 |
Fathollahipour S et al. | Electrospinning of PVA/chitosan nanocomposite nanofibers containing gelatin nanoparticles as a dual drug delivery system. | 2015 | J Biomed Mater Res A | pmid:26112829 |
Xing L et al. | ErmF and ereD are responsible for erythromycin resistance in Riemerella anatipestifer. | 2015 | PLoS ONE | pmid:26107936 |
Dridi B et al. | Differences in antibiotic-induced oxidative stress responses between laboratory and clinical isolates of Streptococcus pneumoniae. | 2015 | Antimicrob. Agents Chemother. | pmid:26100702 |
Czarnetzki C et al. | Erythromycin for Gastric Emptying in Patients Undergoing General Anesthesia for Emergency Surgery: A Randomized Clinical Trial. | 2015 | JAMA Surg | pmid:26083537 |
Patti MG | Erythromycin Use Before Induction of General Endotracheal Anesthesia. | 2015 | JAMA Surg | pmid:26083012 |
Haenen CC et al. | [Rosacea fulminans in pregnancy]. | 2015 | Ned Tijdschr Geneeskd | pmid:26058762 |
Gagliotti C et al. | A regionwide intervention to promote appropriate antibiotic use in children reversed trends in erythromycin resistance to Streptococcus pyogenes. | 2015 | Acta Paediatr. | pmid:26058421 |
Dermota U et al. | Survey of community-associated-methicillin-Resistant Staphylococcus aureus in Slovenia: identification of community-associated and livestock-associated clones. | 2015 | Int. J. Med. Microbiol. | pmid:26055648 |
Park JY et al. | Construction of a shuttle vector based on the small cryptic plasmid pJY33 from Weissella cibaria 33. | 2015 | Plasmid | pmid:25882072 |
Jakubů V et al. | Minimum inhibitory concentrations of erythromycin and other antibiotics for Czech strains of Bordetella pertussis. | 2015 | Epidemiol Mikrobiol Imunol | pmid:25872990 |
Koutsogiannidis CP et al. | Decreased DNA Disruption in the Porcine Neocortex with Erythromycin Preconditioning during Prolonged Hypothermic Circulatory Arrest: Evidence for Neuroprotection. | 2015 | J Card Surg | pmid:25858150 |
KovaÄ J et al. | Antibiotic resistance modulation and modes of action of (-)-α-pinene in Campylobacter jejuni. | 2015 | PLoS ONE | pmid:25830640 |
Abukar AA et al. | Unusual cause of infective endocarditis in an elderly patient with a rare condition. | 2015 | BMJ Case Rep | pmid:25820110 |
Aydin S et al. | Combined effect of erythromycin, tetracycline and sulfamethoxazole on performance of anaerobic sequencing batch reactors. | 2015 | Bioresour. Technol. | pmid:25817031 |
Cui B et al. | Effects of erythromycin on the phenotypic and genotypic biofilm expression in two clinical Staphylococcus capitis subspecies and a functional analysis of Ica proteins in S. capitis. | 2015 | J. Med. Microbiol. | pmid:25813821 |
Chew ML et al. | Effect of the gastrointestinal prokinetic agent erythromycin on the pharmacokinetics of pregabalin controlled-release in healthy individuals: a phase I, randomized crossover trial. | 2015 | Clin Drug Investig | pmid:25808394 |
Ericson JE et al. | Use and Safety of Erythromycin and Metoclopramide in Hospitalized Infants. | 2015 | J. Pediatr. Gastroenterol. Nutr. | pmid:25806675 |
Aydin S et al. | Application of real-time PCR to determination of combined effect of antibiotics on Bacteria, Methanogenic Archaea, Archaea in anaerobic sequencing batch reactors. | 2015 | Water Res. | pmid:25792437 |
Zhu Y et al. | Biochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window". | 2015 | Sci Rep | pmid:25791905 |
Wang P et al. | Serotypes, antibiotic susceptibilities, and multi-locus sequence type profiles of Streptococcus agalactiae isolates circulating in Beijing, China. | 2015 | PLoS ONE | pmid:25781346 |
Zhou Y et al. | Rapid and selective extraction of multiple macrolide antibiotics in foodstuff samples based on magnetic molecularly imprinted polymers. | 2015 | Talanta | pmid:25770599 |
Tojima I et al. | Anti-inflammatory effects of a novel non-antibiotic macrolide, EM900, on mucus secretion of airway epithelium. | 2015 | Auris Nasus Larynx | pmid:25769240 |
Hao H et al. | Identification of Campylobacter jejuni and determination of point mutations associated with macrolide resistance using a multiplex TaqMan MGB real-time PCR. | 2015 | J. Appl. Microbiol. | pmid:25766481 |
Naquin A et al. | Presence of antibiotic resistance genes in a sewage treatment plant in Thibodaux, Louisiana, USA. | 2015 | Bioresour. Technol. | pmid:25662190 |
GarcÃa-Mayor MA et al. | Occurrence of erythromycin residues in sheep milk. Validation of an analytical method. | 2015 | Food Chem. Toxicol. | pmid:25637760 |
van Eijk E et al. | Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5. | 2015 | BMC Genomics | pmid:25636331 |
Gao P et al. | Impacts of coexisting antibiotics, antibacterial residues, and heavy metals on the occurrence of erythromycin resistance genes in urban wastewater. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25631280 |
Lin X et al. | Macrolides for diffuse panbronchiolitis. | 2015 | Cochrane Database Syst Rev | pmid:25618845 |
Sakata H | The change of macrolide resistance rates in group A Streptococcus isolates from children between 2002 and 2013 in Asahikawa city. | 2015 | J. Infect. Chemother. | pmid:25618777 |
Johnson AC et al. | Assessing the concentrations and risks of toxicity from the antibiotics ciprofloxacin, sulfamethoxazole, trimethoprim and erythromycin in European rivers. | 2015 | Sci. Total Environ. | pmid:25617699 |
Wang P et al. | Development of an efficient conjugation-based genetic manipulation system for Pseudoalteromonas. | 2015 | Microb. Cell Fact. | pmid:25612661 |
Chiaverini C et al. | Oral erythromycin therapy in epidermolysis bullosa simplex generalized severe. | 2015 | Br. J. Dermatol. | pmid:25601422 |
Li Z et al. | New erythromycin derivatives enhance β-lactam antibiotics against methicillin-resistant Staphylococcus aureus. | 2015 | Lett. Appl. Microbiol. | pmid:25588530 |
Gardiner SJ et al. | Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children. | 2015 | Cochrane Database Syst Rev | pmid:25566754 |
Azadegan A et al. | Detection of the efflux-mediated erythromycin resistance transposon in Streptococcus pneumoniae. | 2015 | Ann Lab Med | pmid:25553281 |
Wu H et al. | Capturing the target genes of BldD in Saccharopolyspora erythraea using improved genomic SELEX method. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25549616 |
Cetecioglu Z et al. | Acute effect of erythromycin on metabolic transformations of volatile fatty acid mixture under anaerobic conditions. | 2015 | Chemosphere | pmid:25542637 |
Blix HS et al. | Antibiotic prescriptions and cycles of Mycoplasma pneumoniae infections in Norway: can a nationwide prescription register be used for surveillance? | 2015 | Epidemiol. Infect. | pmid:25388750 |
MarÃn M et al. | Clostridium difficile isolates with high linezolid MICs harbor the multiresistance gene cfr. | 2015 | Antimicrob. Agents Chemother. | pmid:25385106 |
Igbinosa IH | Prevalence and detection of antibiotic-resistant determinant in Salmonella isolated from food-producing animals. | 2015 | Trop Anim Health Prod | pmid:25348646 |
Wang Z et al. | Hapten synthesis, monoclonal antibody production and development of a competitive indirect enzyme-linked immunosorbent assay for erythromycin in milk. | 2015 | Food Chem | pmid:25308648 |
Kam Y et al. | Sweat but no gain: inhibiting proliferation of multidrug resistant cancer cells with "ersatzdroges". | 2015 | Int. J. Cancer | pmid:25156304 |
Hawkins PA et al. | Mobile elements and chromosomal changes associated with MLS resistance phenotypes of invasive pneumococci recovered in the United States. | 2015 | Microb. Drug Resist. | pmid:25115711 |
Vallianou N et al. | Prevalence of macrolide, lincosamide, and streptogramin resistance among staphylococci in a tertiary care hospital in Athens, Greece. | 2015 | J Chemother | pmid:25112954 |
Kempe H et al. | Molecularly imprinted polymer nanocarriers for sustained release of erythromycin. | 2015 | Pharm. Res. | pmid:25103333 |
Lo HH et al. | Antibiotic susceptibility pattern and erythromycin resistance mechanisms in beta-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis isolates from central Taiwan. | 2015 | J Microbiol Immunol Infect | pmid:24856419 |
Yang J et al. | Improving heterologous polyketide production in Escherichia coli by transporter engineering. | 2015 | Appl. Microbiol. Biotechnol. | pmid:26062534 |
Muralidharan V and Striepen B | Teaching old drugs new tricks to stop malaria invasion in its tracks. | 2015 | BMC Biol. | pmid:26349580 |
Pavlova A and Gumbart JC | Parametrization of macrolide antibiotics using the force field toolkit. | 2015 | J Comput Chem | pmid:26280362 |
Li X et al. | Differential roles of the hemerythrin-like proteins of Mycobacterium smegmatis in hydrogen peroxide and erythromycin susceptibility. | 2015 | Sci Rep | pmid:26607739 |
Cheng C et al. | Ciprofloxacin plus erythromycin or ambroxol ameliorates endotracheal tube-associated Pseudomonas aeruginosa biofilms in a rat model. | 2015 | Pathol. Res. Pract. | pmid:26601615 |
Feng T et al. | Insights into resistance mechanism of the macrolide biosensor protein MphR(A) binding to macrolide antibiotic erythromycin by molecular dynamics simulation. | 2015 | J. Comput. Aided Mol. Des. | pmid:26564143 |
Daghighi S et al. | Influence of antibiotic pressure on bacterial bioluminescence, with emphasis on Staphylococcus aureus. | 2015 | Int. J. Antimicrob. Agents | pmid:26526893 |
Bravo-Rodriguez K et al. | Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis. | 2015 | Chem. Biol. | pmid:26526102 |
Bérard A et al. | Use of macrolides during pregnancy and the risk of birth defects: a population-based study. | 2015 | Pharmacoepidemiol Drug Saf | pmid:26513406 |
Borges V et al. | Helicobacter pullorum isolated from fresh chicken meat: antibiotic resistance and genomic traits of an emerging foodborne pathogen. | 2015 | Appl. Environ. Microbiol. | pmid:26386065 |
Dixit S and Park JH | Enantioseparation of basic chiral drugs on a carbamoylated erythromycin-zirconia hybrid monolith using capillary electrochromatography. | 2015 | J Chromatogr A | pmid:26372443 |
Michael-Kordatou I et al. | Erythromycin oxidation and ERY-resistant Escherichia coli inactivation in urban wastewater by sulfate radical-based oxidation process under UV-C irradiation. | 2015 | Water Res. | pmid:26360228 |
Arinto-Garcia R et al. | Comparing Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry and Phenotypic and Molecular Methods for Identification of Species within the Streptococcus anginosus Group. | 2015 | J. Clin. Microbiol. | pmid:26354817 |
Han X et al. | Synthesis and structure-activity relationships of novel 9-oxime acylides with improved bactericidal activity. | 2015 | Bioorg. Med. Chem. | pmid:26349628 |
Wróblewska M and Winnicka K | The Effect of Cationic Polyamidoamine Dendrimers on Physicochemical Characteristics of Hydrogels with Erythromycin. | 2015 | Int J Mol Sci | pmid:26343637 |
Ozbayram EG et al. | Acute effects of various antibiotic combinations on acetoclastic methanogenic activity. | 2015 | Environ Sci Pollut Res Int | pmid:25408075 |
Bolukaoto JY et al. | Antibiotic resistance of Streptococcus agalactiae isolated from pregnant women in Garankuwa, South Africa. | 2015 | BMC Res Notes | pmid:26289147 |
Liao CH et al. | DasR is a pleiotropic regulator required for antibiotic production, pigment biosynthesis, and morphological development in Saccharopolyspora erythraea. | 2015 | Appl. Microbiol. Biotechnol. | pmid:26272095 |
Å mitran A et al. | Effects of penicillin and erythromycin on adherence of invasive and noninvasive isolates of Streptococcus pyogenes to laminin. | 2015 | Mem. Inst. Oswaldo Cruz | pmid:26270594 |
Prohl A et al. | Enrofloxacin and macrolides alone or in combination with rifampicin as antimicrobial treatment in a bovine model of acute Chlamydia psittaci infection. | 2015 | PLoS ONE | pmid:25768665 |
Aydın S et al. | The joint acute effect of tetracycline, erythromycin and sulfamethoxazole on acetoclastic methanogens. | 2015 | Water Sci. Technol. | pmid:25909721 |
Mazumdar G and Shome K | Stevens-Johnson syndrome following use of metronidazole in a dental patient. | 2014 Jan-Feb | Indian J Pharmacol | pmid:24550598 |
Chen D et al. | Identification and characterization of a new erythromycin biosynthetic gene cluster in Actinopolyspora erythraea YIM90600, a novel erythronolide-producing halophilic actinomycete isolated from salt field. | 2014 | PLoS ONE | pmid:25250723 |
Brenciani A et al. | ICESp1116, the genetic element responsible for erm(B)-mediated, inducible erythromycin resistance in Streptococcus pyogenes, belongs to the TnGBS family of integrative and conjugative elements. | 2014 | Antimicrob. Agents Chemother. | pmid:24449773 |
Yu ZC et al. | Development of a genetic system for the deep-sea psychrophilic bacterium Pseudoalteromonas sp. SM9913. | 2014 | Microb. Cell Fact. | pmid:24450434 |
Barnes P and Chauhan M | Chancroid - desperate patient makes own diagnosis. | 2014 | Int J STD AIDS | pmid:24535694 |
Hudson BH and Zaher HS | Ribosomes left in the dust: diverse strategies for Peptide-mediated translation stalling. | 2014 | Mol. Cell | pmid:25514181 |
Pinto TC et al. | Conjugative transfer of resistance determinants among human and bovine Streptococcus agalactiae. | 2014 | Braz. J. Microbiol. | pmid:25477908 |
He S et al. | [Clinical analysis of scrub typhus-associated hemophagocytic syndrome]. | 2014 | Zhonghua Er Ke Za Zhi | pmid:25476431 |
Bauer CA and Grimme S | First principles calculation of electron ionization mass spectra for selected organic drug molecules. | 2014 | Org. Biomol. Chem. | pmid:25260171 |
Sugawara E and Nikaido H | Properties of AdeABC and AdeIJK efflux systems of Acinetobacter baumannii compared with those of the AcrAB-TolC system of Escherichia coli. | 2014 | Antimicrob. Agents Chemother. | pmid:25246403 |
Corona PS et al. | Case report: first report of a prosthetic joint infection caused by Facklamia hominis. | 2014 | Diagn. Microbiol. Infect. Dis. | pmid:25245196 |
Kinouchi H et al. | Binding properties of antimicrobial agents to lipid membranes using surface plasmon resonance. | 2014 | Biol. Pharm. Bull. | pmid:25087959 |
Bos JC et al. | Antimicrobial susceptibility of Streptococcus pneumoniae in adult patients with pneumococcal pneumonia in an urban hospital in Mozambique. | 2014 | BMC Res Notes | pmid:24568650 |
Feng Y et al. | Prevalence, distribution, and diversity of Escherichia coli, Staphylococcus aureus, and Salmonella in kiwifruit orchards and processing plants. | 2014 | Foodborne Pathog. Dis. | pmid:25054781 |
Flamm RK et al. | Antimicrobial activity of ceftaroline tested against drug-resistant subsets of Streptococcus pneumoniae from U.S. medical centers. | 2014 | Antimicrob. Agents Chemother. | pmid:24514082 |
Sahu AK et al. | Formulation optimization of erythromycin solid lipid nanocarrier using response surface methodology. | 2014 | Biomed Res Int | pmid:25045692 |
Arakawa K | Genetic and biochemical analysis of the antibiotic biosynthetic gene clusters on the Streptomyces linear plasmid. | 2014 | Biosci. Biotechnol. Biochem. | pmid:25036669 |
Pasquaroli S et al. | Erythromycin- and copper-resistant Enterococcus hirae from marine sediment and co-transfer of erm(B) and tcrB to human Enterococcus faecalis. | 2014 | Diagn. Microbiol. Infect. Dis. | pmid:25017384 |
Yeung SW et al. | Comparison of the effect of penicillins versus erythromycin in preventing neonatal group B streptococcus infection in active carriers following preterm prelabor rupture of membranes. | 2014 | Taiwan J Obstet Gynecol | pmid:25017269 |
Nilsson MF and Webster WS | Effects of macrolide antibiotics on rat embryonic heart function in vitro. | 2014 | Birth Defects Res. B Dev. Reprod. Toxicol. | pmid:24753334 |
Murphree CA et al. | Antibiotic resistance among cultured bacterial isolates from bioethanol fermentation facilities across the United States. | 2014 | Curr. Microbiol. | pmid:24748439 |
Sakamoto N et al. | Bronchiolitis in a patient with ulcerative colitis treated with erythromycin. | 2014 | Intern. Med. | pmid:24739609 |
Szemraj M et al. | Macrolide, lincosamide, and streptogramin B resistance in lipophilic Corynebacteria inhabiting healthy human skin. | 2014 | Microb. Drug Resist. | pmid:24735183 |
Moreno LZ et al. | Characterization of antibiotic resistance in Listeria spp. isolated from slaughterhouse environments, pork and human infections. | 2014 | J Infect Dev Ctries | pmid:24727506 |
Geng Q et al. | Molecular characterization and antimicrobial susceptibility of Streptococcus pneumoniae isolated from children hospitalized with respiratory infections in Suzhou, China. | 2014 | PLoS ONE | pmid:24710108 |
Yosida M et al. | Involvement of cAMP/EPAC/TRPM2 activation in glucose- and incretin-induced insulin secretion. | 2014 | Diabetes | pmid:24824430 |
Di Salvo A et al. | Pharmacokinetics and residue depletion of erythromycin in gilthead sea bream Sparus aurata L. after oral administration. | 2014 | J. Fish Dis. | pmid:23992037 |