erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Bojar RA et al. | Inhibition of erythromycin-resistant propionibacteria on the skin of acne patients by topical erythromycin with and without zinc. | 1994 | Br. J. Dermatol. | pmid:8148274 |
Maes BD et al. | Pharmacological modulation of gastric emptying rate of solids as measured by the carbon labelled octanoic acid breath test: influence of erythromycin and propantheline. | 1994 | Gut | pmid:8150342 |
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Bulgakova VG et al. | [Metabolism of alpha-ketoacids in erythromycin biosynthesis in various strains of Saccharopolyspora erythraea]. | 1993 | Antibiot. Khimioter. | pmid:8166559 |
Kirichenko VN et al. | [Use of protoplast fusion in the selection of erythromycin-producing strains of Saccharopolyspora erythraea]. | 1993 | Antibiot. Khimioter. | pmid:8166562 |
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Tannock GW et al. | Molecular characterization of a plasmid-borne (pGT633) erythromycin resistance determinant (ermGT) from Lactobacillus reuteri 100-63. | 1994 | Plasmid | pmid:8171126 |
Biglin KE et al. | Drug-induced torsades de pointes: a possible interaction of terfenadine and erythromycin. | 1994 | Ann Pharmacother | pmid:8173153 |
Catnach SM et al. | Erythromycin induces supranormal gall bladder contraction in diabetic autonomic neuropathy. | 1993 | Gut | pmid:8174966 |
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Menninger JR et al. | Erythromycin, lincosamides, peptidyl-tRNA dissociation, and ribosome editing. | 1994 | Mol. Gen. Genet. | pmid:8177219 |
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Akl K and Dawod ST | Erythromycin-induced abdominal pain. | 1994 Jan-Feb | Br J Clin Pract | pmid:8179992 |
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Sims PJ et al. | Erythromycin lactobionate toxicity in preterm neonates. | 1994 | Pediatr. Infect. Dis. J. | pmid:8190550 |
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Spangler SK et al. | Effect of CO2 on susceptibilities of anaerobes to erythromycin, azithromycin, clarithromycin, and roxithromycin. | 1994 | Antimicrob. Agents Chemother. | pmid:8192445 |
Stamler DA et al. | Azithromycin pharmacokinetics and intracellular concentrations in Legionella pneumophila-infected and uninfected guinea pigs and their alveolar macrophages. | 1994 | Antimicrob. Agents Chemother. | pmid:8192446 |
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Salzberg R | A randomized, open, comparative study of brodimoprim versus erythromycin in patients with acute tonsillitis or bronchitis. | 1993 | J Chemother | pmid:8195854 |
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Anastasio GD et al. | Impact of compliance and side effects on the clinical outcome of patients treated with oral erythromycin. | 1994 Mar-Apr | Pharmacotherapy | pmid:8197045 |
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