erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lim KS et al. | Antimicrobial susceptibility of bifidobacteria. | 1993 | J. Dairy Sci. | pmid:8408866 |
| Holmberg K et al. | Antimicrobial in vitro susceptibility of actinomyces israelii and arachnia propionica. | 1977 | Scand. J. Infect. Dis. | pmid:841278 |
| Ahrens F et al. | [Legionellosis in a newborn infant]. | 1993 | Monatsschr Kinderheilkd | pmid:8413346 |
| Saitoh S et al. | Mycoplasma pneumoniae infection may cause striatal lesions leading to acute neurologic dysfunction. | 1993 | Neurology | pmid:8413990 |
| Dan M and Feigl D | Erythromycin-associated hypotension. | 1993 | Pediatr. Infect. Dis. J. | pmid:8414782 |
| Paradisi M et al. | Efficacy of topical erythromycin in treatment of perianal streptococcal dermatitis. | 1993 | Pediatr Dermatol | pmid:8415314 |
| Arayne MS and Sultana N | Erythromycin-antacid interaction. | 1993 | Pharmazie | pmid:8415858 |
| Pecevski J et al. | The effect of erythromycin and its thiocarbamide derivative on the induction of meiotic chromosome rearrangements in irradiated male mice. | 1977 | Strahlentherapie | pmid:841613 |
| Stassi D et al. | Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis. | 1993 | J. Bacteriol. | pmid:8416893 |
| Rello J et al. | A three-year study of severe community-acquired pneumonia with emphasis on outcome. | 1993 | Chest | pmid:8417885 |
| Pauker SG and Kopelman RI | Weak reasoning: diagnosis by drug reaction. | 1993 | N. Engl. J. Med. | pmid:8419820 |
| Kadota J et al. | A mechanism of erythromycin treatment in patients with diffuse panbronchiolitis. | 1993 | Am. Rev. Respir. Dis. | pmid:8420410 |
| Camilleri M | The current role of erythromycin in the clinical management of gastric emptying disorders. | 1993 | Am. J. Gastroenterol. | pmid:8424415 |
| Keshavarzian A and Isaac RM | Erythromycin accelerates gastric emptying of indigestible solids and transpyloric migration of the tip of an enteral feeding tube in fasting and fed states. | 1993 | Am. J. Gastroenterol. | pmid:8424419 |
| Mantides A et al. | The effect of erythromycin in gastric emptying of solids and hypertonic liquids in healthy subjects. | 1993 | Am. J. Gastroenterol. | pmid:8424420 |
| Richards RD et al. | The treatment of idiopathic and diabetic gastroparesis with acute intravenous and chronic oral erythromycin. | 1993 | Am. J. Gastroenterol. | pmid:8424421 |
| Bonacini M et al. | Effect of intravenous erythromycin on postoperative ileus. | 1993 | Am. J. Gastroenterol. | pmid:8424422 |
| Noah PK et al. | Evaluation of oral erythromycin and local isoniazid instillation therapy in infants with Bacillus Calmette-Guérin lymphadenitis and abscesses. | 1993 | Pediatr. Infect. Dis. J. | pmid:8426771 |
| O'Brien JF et al. | Dexamethasone as adjuvant therapy for severe acute pharyngitis. | 1993 | Ann Emerg Med | pmid:8427434 |
| Lees AW and Tyrrell WF | Diagnosis of legionnaires' disease. | 1979 | Lancet | pmid:84289 |
| Sacristán JA and Soto J | Erythromycin ototoxicity: methodology and conclusions. | 1993 | Am. J. Med. | pmid:8430720 |
| Maskin SL | Infectious scleritis after a diabetic foot ulcer. | 1993 | Am. J. Ophthalmol. | pmid:8430739 |
| Stacher G et al. | Erythromycin effects on gastric emptying, antral motility and plasma motilin and pancreatic polypeptide concentrations in anorexia nervosa. | 1993 | Gut | pmid:8432466 |
| Sladek GG and Frame JN | Rhodococcus equi causing bacteremia in an adult with acute leukemia. | 1993 | South. Med. J. | pmid:8434305 |
| Marrie TJ | Mycoplasma pneumoniae pneumonia requiring hospitalization, with emphasis on infection in the elderly. | 1993 | Arch. Intern. Med. | pmid:8435028 |
| Roos K et al. | Interfering alpha-streptococci as a protection against recurrent streptococcal tonsillitis in children. | 1993 | Int. J. Pediatr. Otorhinolaryngol. | pmid:8436458 |
| Falck G | [Therapy of whooping cough. Treatment for the "privileged", what about the others?]. | 1993 | Lakartidningen | pmid:8437454 |
| Knottenbelt DC | Rhodococcus equi infection in foals: a report of an outbreak on a thoroughbred stud in Zimbabwe. | 1993 | Vet. Rec. | pmid:8438546 |
| Bartkowski RR et al. | Sufentanil disposition. Is it affected by erythromycin administration? | 1993 | Anesthesiology | pmid:8439020 |
| Catnach SM et al. | Dose-dependent stimulation of gallbladder contraction by intravenous erythromycin in man. | 1993 | Aliment. Pharmacol. Ther. | pmid:8439638 |
| Carol P et al. | Erythromycin and 5S rRNA binding properties of the spinach chloroplast ribosomal protein CL22. | 1993 | Nucleic Acids Res. | pmid:8441674 |
| Fietta A et al. | Bioactivity of flurithromycin and other macrolides against intracellular susceptible staphylococci. | 1993 | Chemotherapy | pmid:8444060 |
| Tsakris A and Maniatis AN | Inducible type of erythromycin resistance among group B streptococci isolated in Greece. | 1993 | J. Antimicrob. Chemother. | pmid:8444664 |
| Lehtonen L et al. | Erythromycin and 2'-acetyl erythromycin concentrations in plasma and pelvic tissues after repeated doses of erythromycin acistrate. | 1993 | Arzneimittelforschung | pmid:8447849 |
| Andersen JF et al. | Substrate specificity of 6-deoxyerythronolide B hydroxylase, a bacterial cytochrome P450 of erythromycin A biosynthesis. | 1993 | Biochemistry | pmid:8448148 |
| Chien SM et al. | Treatment of community-acquired pneumonia. A multicenter, double-blind, randomized study comparing clarithromycin with erythromycin. Canada-Sweden Clarithromycin-Pneumonia Study Group. | 1993 | Chest | pmid:8449054 |
| Leadlay PF et al. | The erythromycin-producing polyketide synthase. | 1993 | Biochem. Soc. Trans. | pmid:8449298 |
| Bevitt DJ et al. | Mutagenesis of the dehydratase active site in the erythromycin-producing polyketide synthase. | 1993 | Biochem. Soc. Trans. | pmid:8449310 |
| Roberts GA et al. | 6-Deoxyerythronolide B synthase 3 from Saccharopolyspora erythraea: over-expression in Escherichia coli, purification and characterisation. | 1993 | Biochem. Soc. Trans. | pmid:8449313 |
| Ogino J et al. | [Effect of erythromycin on anti staphylococcal activity and dye production of Pseudomonas aeruginosa isolated from clinical materials]. | 1993 | Kansenshogaku Zasshi | pmid:8450271 |
| Kusano S et al. | [Effect of erythromycin on neutrophil adhesion molecules]. | 1993 | Kansenshogaku Zasshi | pmid:8450276 |
| Echizen H et al. | A potent inhibitory effect of erythromycin and other macrolide antibiotics on the mono-N-dealkylation metabolism of disopyramide with human liver microsomes. | 1993 | J. Pharmacol. Exp. Ther. | pmid:8450476 |
| Coonan K and Kaplan EL | Therapeutic implications of erythromycin resistance in group A streptococci. | 1993 | Pediatr. Infect. Dis. J. | pmid:8451111 |
| Lindstrom TD et al. | Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers. | 1993 | Antimicrob. Agents Chemother. | pmid:8452357 |
| Peterson MC et al. | Prosthetic hip infection and bacteremia due to Campylobacter jejuni in a patient with AIDS. | 1993 | Clin. Infect. Dis. | pmid:8452956 |
| Karlowsky J et al. | A review of commonly prescribed oral antibiotics in general dentistry. | 1993 | J Can Dent Assoc | pmid:8453530 |
| Olkkola KT et al. | A potentially hazardous interaction between erythromycin and midazolam. | 1993 | Clin. Pharmacol. Ther. | pmid:8453848 |
| Edelbroek MA et al. | Effects of erythromycin on gastric emptying, alcohol absorption and small intestinal transit in normal subjects. | 1993 | J. Nucl. Med. | pmid:8455074 |
| Clotet B et al. | Rhodococcus equi infection in HIV-infected patients. | 1993 | J. Acquir. Immune Defic. Syndr. | pmid:8455149 |
| Spach DH et al. | Endocarditis caused by Rochalimaea quintana in a patient infected with human immunodeficiency virus. | 1993 | J. Clin. Microbiol. | pmid:8458964 |
| Hoogeterp JJ et al. | Activity of erythromycin and clindamycin in an experimental Staphylococcus aureus infection in normal and granulocytopenic mice. A comparative in vivo and in vitro study. | 1993 | Scand. J. Infect. Dis. | pmid:8460336 |
| Fiorucci S and Morelli A | Motilin and erythromycin stimulate pepsinogen secretion by chief cells isolated from guinea pig stomach. | 1993 | Gastroenterology | pmid:8462791 |
| Eady EA et al. | Distribution of genes encoding erythromycin ribosomal methylases and an erythromycin efflux pump in epidemiologically distinct groups of staphylococci. | 1993 | J. Antimicrob. Chemother. | pmid:8463168 |
| Mantzoros C et al. | Skin lesion in an acutely ill man with HIV. | 1993 | Hosp. Pract. (Off. Ed.) | pmid:8463358 |
| Driscoll MS et al. | Long-term oral antibiotics for acne: is laboratory monitoring necessary? | 1993 | J. Am. Acad. Dermatol. | pmid:8463461 |
| Hahn D | Erythromycin reduces neutrophils and neutrophil-derived elastolytic-like activity in the lower respiratory tract of bronchiolitis patients. | 1993 | Am. Rev. Respir. Dis. | pmid:8466109 |
| Vasquez EM et al. | Clinically significant hearing loss in renal allograft recipients treated with intravenous erythromycin. | 1993 | Arch. Intern. Med. | pmid:8466379 |
| Sabbah A | [Teldane update. Interview with Dr. Alfred Sabbah, chief of the immuno-allergology laboratory of the C.H.U. d'Angers. Interview by Dr. Pierre Ceddaha]. | 1993 | Allerg Immunol (Paris) | pmid:8466639 |
| Magat AH et al. | Double-blind randomized study comparing amoxicillin and erythromycin for the treatment of Chlamydia trachomatis in pregnancy. | 1993 | Obstet Gynecol | pmid:8469466 |
| Weber FH et al. | Erythromycin: a motilin agonist and gastrointestinal prokinetic agent. | 1993 | Am. J. Gastroenterol. | pmid:8470625 |
| Smith GR and Thornton EA | Effect of disturbance of the gastrointestinal microflora on the faecal excretion of Fusobacterium necrophorum biovar A. | 1993 | Epidemiol. Infect. | pmid:8472777 |
| Garlaschi ML et al. | Antimicrobial resistance among clinical isolates of Haemophilus influenzae in northern Italy. Collaborative Study on Pediatric Infectious Diseases. | 1993 | Eur. J. Epidemiol. | pmid:8472803 |
| Gannon H | Ureaplasma urealyticum and its role in neonatal lung disease. | 1993 | Neonatal Netw | pmid:8474408 |
| Husfeldt P et al. | Antibiotic treatment of sinusitis in general practice. A double-blind study comparing ofloxacin and erythromycin. | 1993 | Eur Arch Otorhinolaryngol | pmid:8476582 |
| Endou K et al. | Implication of cohesive binding of a macrolide antibiotic, rokitamycin, to ribosomes from Staphylococcus aureus. | 1993 | J. Antibiot. | pmid:8478265 |
| Ruggiero G et al. | Clinical efficacy of dirithromycin versus miocamycin in tonsillopharyngitis. | 1993 | J. Antimicrob. Chemother. | pmid:8478300 |
| Jacobson K | Clinical efficacy of dirithromycin in pneumonia. | 1993 | J. Antimicrob. Chemother. | pmid:8478303 |
| Sides GD | Clinical efficacy of dirithromycin in acute exacerbations of chronic bronchitis. | 1993 | J. Antimicrob. Chemother. | pmid:8478304 |
| Gaillat J | A multicentre study comparing the safety and efficacy of dirithromycin with erythromycin in the treatment of bronchitis. | 1993 | J. Antimicrob. Chemother. | pmid:8478305 |
| Pozzi E | Clinical efficacy of dirithromycin versus miocamycin in the treatment of acute bronchitis or acute exacerbations of chronic bronchitis. | 1993 | J. Antimicrob. Chemother. | pmid:8478306 |
| Derriennic M and Escande JP | Dirithromycin in the treatment of skin and skin structure infections. | 1993 | J. Antimicrob. Chemother. | pmid:8478307 |
| Varanese L | Pharmacokinetics and safety of dirithromycin in the elderly. | 1993 | J. Antimicrob. Chemother. | pmid:8478308 |
| Sides GD and Conforti PM | Safety profile of dirithromycin. | 1993 | J. Antimicrob. Chemother. | pmid:8478309 |
| Barry AL et al. | Dirithromycin disc susceptibility tests: interpretative criteria and quality control parameters. | 1993 | J. Antimicrob. Chemother. | pmid:8478310 |
| Bauernfeind A | In-vitro activity of dirithromycin in comparison with other new and established macrolides. | 1993 | J. Antimicrob. Chemother. | pmid:8478311 |
| Labro MT et al. | Modulation of human polymorphonuclear neutrophil function by macrolides: preliminary data concerning dirithromycin. | 1993 | J. Antimicrob. Chemother. | pmid:8478312 |
| Sides GD et al. | Pharmacokinetics of dirithromycin. | 1993 | J. Antimicrob. Chemother. | pmid:8478313 |
| Bergogne-Bérézin E | Tissue distribution of dirithromycin: comparison with erythromycin. | 1993 | J. Antimicrob. Chemother. | pmid:8478314 |
| Derriennic M et al. | Dirithromycin in the treatment of streptococcal pharyngitis. | 1993 | J. Antimicrob. Chemother. | pmid:8478315 |
| Müller O and Wettich K | Clinical efficacy of dirithromycin in pharyngitis and tonsillitis. | 1993 | J. Antimicrob. Chemother. | pmid:8478316 |
| Derby LE et al. | Erythromycin-associated cholestatic hepatitis. | 1993 | Med. J. Aust. | pmid:8479375 |
| Kawamura O et al. | Effect of erythromycin on interdigestive gastrointestinal contractile activity and plasma motilin concentration in humans. | 1993 | Dig. Dis. Sci. | pmid:8482186 |
| Ohtawa M et al. | Mechanism of gastroprokinetic effect of EM523, an erythromycin derivative, in dogs. | 1993 | Gastroenterology | pmid:8482446 |
| Orr PH et al. | Randomized placebo-controlled trials of antibiotics for acute bronchitis: a critical review of the literature. | 1993 | J Fam Pract | pmid:8482934 |
| Gustafsson BE et al. | Prolonged induction of germfree bile acid pattern in conventional rats by antibiotics. | 1977 | Acta Med Scand | pmid:848350 |
| Rathore MH and Jenkins SG | Group A beta-hemolytic Streptococcus: issue of resistance. | 1993 | Pediatr. Infect. Dis. J. | pmid:8483636 |
| Doménech J et al. | [Evaluation of the possible ototoxicity of josamycin by high frequency audiometry]. | 1993 | An Otorrinolaringol Ibero Am | pmid:8484488 |
| Savolainen S et al. | Peritonsillar abscess. Clinical and microbiologic aspects and treatment regimens. | 1993 | Arch. Otolaryngol. Head Neck Surg. | pmid:8484941 |
| Soriano F and Fernández-Roblas R | High rates of erythromycin-resistant Streptococcus pneumoniae among penicillin-resistant strains. | 1993 | J. Antimicrob. Chemother. | pmid:8486579 |
| Grøndahl TO and Langmoen IA | Epileptogenic effect of antibiotic drugs. | 1993 | J. Neurosurg. | pmid:8487076 |
| Piras G et al. | Cloning and sequencing of the low-affinity penicillin-binding protein 3r-encoding gene of Enterococcus hirae S185: modular design and structural organization of the protein. | 1993 | J. Bacteriol. | pmid:8491705 |
| Tateda K et al. | Effects of sub-MICs of erythromycin and other macrolide antibiotics on serum sensitivity of Pseudomonas aeruginosa. | 1993 | Antimicrob. Agents Chemother. | pmid:8494362 |
| Tankovic J et al. | Antimicrobial susceptibility of Pediococcus spp. and genetic basis of macrolide resistance in Pediococcus acidilactici HM3020. | 1993 | Antimicrob. Agents Chemother. | pmid:8494376 |
| Foweraker JE et al. | Ecology of Haemophilus influenzae and Haemophilus parainfluenzae in sputum and saliva and effects of antibiotics on their distribution in patients with lower respiratory tract infections. | 1993 | Antimicrob. Agents Chemother. | pmid:8494378 |
| Edelstein PH and Edelstein MA | In vitro activity of RP 74501-RP 74502, a novel streptogramin antimicrobial mixture, against clinical isolates of Legionella species. | 1993 | Antimicrob. Agents Chemother. | pmid:8494390 |
| Tredaniel J et al. | Diffuse panbronchiolitis: efficacy of low-dose erythromycin. | 1993 | Respir Med | pmid:8497706 |
| Prather CM et al. | Gastric axial forces in experimentally delayed and accelerated gastric emptying. | 1993 | Am. J. Physiol. | pmid:8498519 |
| Iino Y et al. | Erythromycin therapy for otitis media with effusion in sinobronchial syndrome. | 1993 | Arch. Otolaryngol. Head Neck Surg. | pmid:8499096 |
| Levison ME et al. | In vitro activity and clinical efficacy of clindamycin in the treatment of infections due to anaerobic bacteria. | 1977 | J. Infect. Dis. | pmid:850091 |
| Watanabe Y et al. | Chemical modification of erythromycins. IX. Selective methylation at the C-6 hydroxyl group of erythromycin A oxime derivatives and preparation of clarithromycin. | 1993 | J. Antibiot. | pmid:8501007 |