erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kiss L et al. | Coagulase-negative staphylococci in air samples from operating theatres. | 1996 | Acta Microbiol Immunol Hung | pmid:8806942 |
| Pankuch GA et al. | Antipneumococcal activities of RP 59500 (quinupristin-dalfopristin), penicillin G, erythromycin, and sparfloxacin determined by MIC and rapid time-kill methodologies. | 1996 | Antimicrob. Agents Chemother. | pmid:8807057 |
| Roberts MC et al. | Characterization of tetracycline and erythromycin resistance determinants in Treponema denticola. | 1996 | Antimicrob. Agents Chemother. | pmid:8807063 |
| Tamaoki J et al. | Effects of roxithromycin and erythromycin on interleukin 8-induced neutrophil recruitment and goblet cell secretion in guinea pig tracheas. | 1996 | Antimicrob. Agents Chemother. | pmid:8807072 |
| de Graaf-Strukowska L et al. | Two non-diabetic patients with delayed gastric emptying during CAPD effectively treated with erythromycin. | 1995 | Nephrol. Dial. Transplant. | pmid:8808241 |
| Cellesi C et al. | Susceptibility of macrolide and beta-lactam antibiotics of Streptococcus pyogenes strains isolated over a four-year period in central Italy. | 1996 | J Chemother | pmid:8808714 |
| Blandino G et al. | In vitro activity of cefdinir against respiratory pathogens isolated in Sicily with reference to beta-lactamase production. | 1996 | J Chemother | pmid:8808715 |
| Hall LM et al. | Genetic relatedness within and between serotypes of Streptococcus pneumoniae from the United Kingdom: analysis of multilocus enzyme electrophoresis, pulsed-field gel electrophoresis, and antimicrobial resistance patterns. | 1996 | J. Clin. Microbiol. | pmid:8815096 |
| Pillans PI | Drug associated hepatic reactions in New Zealand: 21 years experience. | 1996 | N. Z. Med. J. | pmid:8816722 |
| Ding SL et al. | Acute interstitial nephritis and acute renal failure following erythromycin treatment: case report. | 1996 | N. Z. Med. J. | pmid:8816724 |
| Enhanced surveillance of non-toxigenic Corynebacterium diphtheriae infections. | 1996 | Commun Dis Rep CDR Wkly | pmid:8821021 | |
| Müller-Wening W et al. | [Clinical and radiological findings in 78 children during the 1974/75 mycoplasma-pneumonia-epidemic (author's transl)]. | 1977 | Monatsschr Kinderheilkd | pmid:882103 |
| Luurila H et al. | Interaction between erythromycin and the benzodiazepines diazepam and flunitrazepam. | 1996 | Pharmacol. Toxicol. | pmid:8822046 |
| Steiner A and Roussel AJ | Drugs coordinating and restoring gastrointestinal motility and their effect on selected hypodynamic gastrointestinal disorders in horses and cattle. | 1995 | Zentralbl Veterinarmed A | pmid:8822186 |
| Wang Y et al. | RNA molecules that specifically and stoichiometrically bind aminoglycoside antibiotics with high affinities. | 1996 | Biochemistry | pmid:8823168 |
| Kao CM et al. | Evidence for two catalytically independent clusters of active sites in a functional modular polyketide synthase. | 1996 | Biochemistry | pmid:8823171 |
| Funabashi Y et al. | Bioactive metabolites of EM574 and EM523, erythromycin derivatives having strong gastrointestinal motor stimulating activity. | 1996 | J. Antibiot. | pmid:8823513 |
| Funabashi Y et al. | Microbial conversion of EM574 and EM523, gastrointestinal motor stimulating agents. | 1996 | J. Antibiot. | pmid:8823514 |
| Brunner H | [Pneumonia caused by mycoplasma pneumoniae. On the differential diagnosis of acute pneumonias (author's transl)]. | 1977 | Schweiz. Rundsch. Med. Prax. | pmid:882509 |
| Zhang XJ and Thomas PE | Erythromycin as a specific substrate for cytochrome P4503A isozymes and identification of a high-affinity erythromycin N-demethylase in adult female rats. | 1996 | Drug Metab. Dispos. | pmid:8825186 |
| Scrivener CJ and Vizard AL | Efficacy of a single dose of erythromycin or penicillin/streptomycin for the treatment of ovine dermatophilosis. | 1995 | Aust. Vet. J. | pmid:8825319 |
| Deguchi K et al. | [Antimicrobial activities of cefozopran against Streptococcus pneumoniae from children]. | 1996 | Jpn J Antibiot | pmid:8828071 |
| Steele RW | Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis. | 1996 | Clin Pediatr (Phila) | pmid:8829012 |
| Barrio J et al. | Rosacea-like demodicosis in an HIV-positive child. | 1996 | Dermatology (Basel) | pmid:8829498 |
| Donadio S et al. | Erythromycin production in Saccharopolyspora erythraea does not require a functional propionyl-CoA carboxylase. | 1996 | Mol. Microbiol. | pmid:8830278 |
| Hong T et al. | Direct application of Etest to gram-positive cocci from blood cultures: quick and reliable minimum inhibitory concentration data. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8831041 |
| Biedenbach DJ and Jones RN | The comparative antimicrobial activity of levofloxacin tested against 350 clinical isolates of streptococci. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8831045 |
| Enomoto F et al. | [Evaluation of the effect of erythromycin on otitis media with effusion in experimental rat models]. | 1996 | Nippon Jibiinkoka Gakkai Kaiho | pmid:8831236 |
| Liu J et al. | Inhibitory effect of erythromycin on ion transport by stria vascularis and vestibular dark cells. | 1996 | Acta Otolaryngol. | pmid:8831844 |
| Luo G et al. | Erythromycin biosynthesis: exploiting the catalytic versatility of the modular polyketide synthase. | 1996 | Bioorg. Med. Chem. | pmid:8831969 |
| Edelstein PH et al. | Activity of trovafloxacin (CP-99,219) against Legionella isolates: in vitro activity, intracellular accumulation and killing in macrophages, and pharmacokinetics and treatment of guinea pigs with L. pneumophila pneumonia. | 1996 | Antimicrob. Agents Chemother. | pmid:8834872 |
| Cooper AJ et al. | The erythromycin resistance gene from the Bacteroides conjugal transposon Tcr Emr 7853 is nearly identical to ermG from Bacillus sphaericus. | 1996 | Antimicrob. Agents Chemother. | pmid:8834912 |
| Roseghini M et al. | Choline esters and biogenic amines in the hypobranchial gland of 55 molluscan species of the neogastropod Muricoidea superfamily. | 1996 | Toxicon | pmid:8835333 |
| Lanbeck P and Paulsen O | Cytotoxic effects of four antibiotics on endothelial cells. | 1995 | Pharmacol. Toxicol. | pmid:8835360 |
| Ehret JM et al. | A clinical isolate of Neisseria gonorrhoeae with in vitro resistance to erythromycin and decreased susceptibility to azithromycin. | 1996 Jul-Aug | Sex Transm Dis | pmid:8836018 |
| Chapuis C et al. | An economic approach to the MIC. | 1996 | Zentralbl. Bakteriol. | pmid:8837370 |
| Schierholz JM et al. | Drug delivery concepts for the efficacious prevention of foreign-body infections. | 1996 | Zentralbl. Bakteriol. | pmid:8837400 |
| Viravan C et al. | A prospective clinical and bacteriologic study of inguinal buboes in Thai men. | 1996 | Clin. Infect. Dis. | pmid:8838178 |
| Tschida SJ et al. | QTc-interval prolongation associated with slow intravenous erythromycin lactobionate infusions in critically ill patients: a prospective evaluation and review of the literature. | 1996 Jul-Aug | Pharmacotherapy | pmid:8840374 |
| Vaara M and Porro M | Group of peptides that act synergistically with hydrophobic antibiotics against gram-negative enteric bacteria. | 1996 | Antimicrob. Agents Chemother. | pmid:8843284 |
| Sutcliffe J et al. | Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system. | 1996 | Antimicrob. Agents Chemother. | pmid:8843287 |
| Ednie LM et al. | Comparative activities of clarithromycin, erythromycin, and azithromycin against penicillin-susceptible and penicillin-resistant pneumococci. | 1996 | Antimicrob. Agents Chemother. | pmid:8843313 |
| Shryock TR et al. | Minimum inhibitory concentration breakpoints and disk diffusion inhibitory zone interpretive criteria for tilmicosin susceptibility testing against Pasteurella spp. associated with bovine respiratory disease. | 1996 | J. Vet. Diagn. Invest. | pmid:8844577 |
| Kim KH et al. | Periauricular eczematization in childhood atopic dermatitis. | 1996 Jul-Aug | Pediatr Dermatol | pmid:8844743 |
| O'Hara K and Yamamoto K | Reaction of roxithromycin and clarithromycin with macrolide-inactivating enzymes from highly erythromycin-resistant Escherichia coli. | 1996 | Antimicrob. Agents Chemother. | pmid:8849224 |
| Doern GV et al. | Emergence of high rates of antimicrobial resistance among viridans group streptococci in the United States. | 1996 | Antimicrob. Agents Chemother. | pmid:8849246 |
| Masuda N et al. | Quantitative correlation between susceptibility and OprJ production in NfxB mutants of Pseudomonas aeruginosa. | 1996 | Antimicrob. Agents Chemother. | pmid:8849250 |
| Weiss K et al. | Comparison of antimicrobial susceptibilities of Corynebacterium species by broth microdilution and disk diffusion methods. | 1996 | Antimicrob. Agents Chemother. | pmid:8849254 |
| Wondrack L et al. | Clinical strain of Staphylococcus aureus inactivates and causes efflux of macrolides. | 1996 | Antimicrob. Agents Chemother. | pmid:8849266 |
| Amsden GW | Erythromycin, clarithromycin, and azithromycin: are the differences real? | 1996 Jan-Feb | Clin Ther | pmid:8851453 |
| Vermot D et al. | Efficacy of clarithromycin versus that of clindamycin for single-dose prophylaxis of experimental streptococcal endocarditis. | 1996 | Antimicrob. Agents Chemother. | pmid:8851620 |
| Chang AD et al. | Bacillary angiomatosis associated with extensive esophageal polyposis: a new mucocutaneous manifestation of acquired immunodeficiency disease (AIDS). | 1996 | Am. J. Gastroenterol. | pmid:8855753 |
| Raab W | [Acute side effects of erythromycin, lincomycin and clindamycin]. | 1977 | Int J Clin Pharmacol Biopharm | pmid:885668 |
| Hofstetter A | [Mycoplasma infections of urogenital tract]. | 1977 | Hautarzt | pmid:885718 |
| Watkins PB | Erythromycin breath test and clinical transplantation. | 1996 | Ther Drug Monit | pmid:8857552 |
| Vanakoski J et al. | Grapefruit juice does not enhance the effects of midazolam and triazolam in man. | 1996 | Eur. J. Clin. Pharmacol. | pmid:8858279 |
| Lacey RW | Lack of evidence for mutation to erythromycin resistance in clinical strains of Staphylococcus aureus. | 1977 | J. Clin. Pathol. | pmid:886013 |
| Burnens AP et al. | Sequential development of resistance to fluoroquinolones and erythromycin in an isolate of Campylobacter jejuni. | 1996 | Zentralbl. Bakteriol. | pmid:8861869 |
| Xu G et al. | Effect of macrolide antibiotics on macrophage functions. | 1996 | Microbiol. Immunol. | pmid:8865152 |
| Ogawa T et al. | [Effect of erythromycin on early delayed gastric emptying after pylorus preserving pancreatoduodenectomy--case report]. | 1996 | Nihon Shokakibyo Gakkai Zasshi | pmid:8865759 |
| Toyota K et al. | A study of pyloric function after pylorus-preserving pancreatoduodenectomy in the canine model. | 1995 | J Smooth Muscle Res | pmid:8867940 |
| Shiba Y et al. | [Mechanism of increased gastric motility effect of EM523]. | 1995 | J Smooth Muscle Res | pmid:8867984 |
| Sato M et al. | [Erythromycin derivative EM574 with motilin agonistic effect on human gastric antrum]. | 1995 | J Smooth Muscle Res | pmid:8867985 |
| Ridgway GL and Oriel JD | Treatment of neonatal inclusion blennorrhea. | 1977 | N. Engl. J. Med. | pmid:887138 |
| Jones DR et al. | Determination of cytochrome P450 3A4/5 activity in vivo with dextromethorphan N-demethylation. | 1996 | Clin. Pharmacol. Ther. | pmid:8873685 |
| Gómez J et al. | Prospective study of epidemiology and prognostic factors in community-acquired pneumonia. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8874072 |
| Kürekçi AE et al. | The frequency of resistance to erythromycin in group A streptococci in Ankara. | 1996 | Eur. J. Pediatr. | pmid:8874111 |
| Uwaydah M et al. | Antimicrobial resistance of clinical isolates of Streptococcus pneumoniae in Lebanon. | 1996 | J. Antimicrob. Chemother. | pmid:8877543 |
| Amin AS and Issa YM | Selective spectrophotometric method for the determination of erythromycin and its esters in pharmaceutical formulations using gentiana violet. | 1996 | J Pharm Biomed Anal | pmid:8877871 |
| Pankuch GA et al. | MIC and time-kill study of antipneumococcal activities of RPR 106972 (a new oral streptogramin), RP 59500 (quinupristin-dalfopristin), pyostacine (RP 7293), penicillin G, cefotaxime, erythromycin, and clarithromycin against 10 penicillin-susceptible and -resistant pneumococci. | 1996 | Antimicrob. Agents Chemother. | pmid:8878583 |
| Alcaide F et al. | In vitro activities of eight macrolide antibiotics and RP-59500 (quinupristin-dalfopristin) against viridans group streptococci isolated from blood of neutropenic cancer patients. | 1996 | Antimicrob. Agents Chemother. | pmid:8878591 |
| Valsecchi R et al. | Contact allergy to erythromycin. | 1996 | Contact Derm. | pmid:8879932 |
| Davies P et al. | Erythromycin resistance of Campylobacter isolates from pigs. | 1996 | Vet. Rec. | pmid:8883355 |
| Viluksela M et al. | Cytotoxicity of macrolide antibiotics in a cultured human liver cell line. | 1996 | J. Antimicrob. Chemother. | pmid:8889721 |
| Biedenbach D et al. | Comparative in-vitro activity of quinupristin/dalfopristin (RP 59500) tested against penicillin-and macrolide-resistant pneumococci by the Etest. | 1996 | J. Antimicrob. Chemother. | pmid:8889731 |
| Benson JM et al. | Tonsillar tissue penetration of dirithromycin after multiple doses. | 1996 | J Clin Pharmacol | pmid:8889904 |
| Tateda K et al. | Direct evidence for antipseudomonal activity of macrolides: exposure-dependent bactericidal activity and inhibition of protein synthesis by erythromycin, clarithromycin, and azithromycin. | 1996 | Antimicrob. Agents Chemother. | pmid:8891128 |
| Hunt Gerardo S et al. | Comparison of Etest to broth microdilution method for testing Streptococcus pneumoniae susceptibility to levofloxacin and three macrolides. | 1996 | Antimicrob. Agents Chemother. | pmid:8891154 |
| Wintermeyer SM et al. | Dirithromycin: a new macrolide. | 1996 | Ann Pharmacother | pmid:8893122 |
| Clarke JS et al. | Preoperative oral antibiotics reduce septic complications of colon operations: results of prospective, randomized, double-blind clinical study. | 1977 | Ann. Surg. | pmid:889372 |
| Shinagawa S et al. | Exacerbation of tracheobronchitis due to nontoxigenic Corynebacterium diphtheriae. | 1996 | Intern. Med. | pmid:8894741 |
| Ross JD et al. | Efficacy of anti-chlamydial therapy with oxytetracycline and erythromycin. | 1996 Aug-Sep | Int J STD AIDS | pmid:8894832 |
| Matschiner S et al. | Influence of ion pairing on ex vivo penetration of erythromycin into sebaceous follicles. | 1996 | Skin Pharmacol. | pmid:8896118 |
| Scott DW et al. | Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. | 1996 | Can. Vet. J. | pmid:8896878 |
| Nay TS | Extra-pulmonary Rhodococcus equi in a thoroughbred foal. | 1996 | Can. Vet. J. | pmid:8896881 |
| Wadowsky RM et al. | Multiplex PCR-based assay for detection of Bordetella pertussis in nasopharyngeal swab specimens. | 1996 | J. Clin. Microbiol. | pmid:8897157 |
| Jorgensen JH et al. | Development of interpretive criteria and quality control limits for macrolide and clindamycin susceptibility testing of Streptococcus pneumoniae. | 1996 | J. Clin. Microbiol. | pmid:8897164 |
| Jayaraman SC et al. | Topical delivery of erythromycin from various formulations: an in vivo hairless mouse study. | 1996 | J Pharm Sci | pmid:8897275 |
| Yau TH and Butrus SI | Presumed bilateral herpes zoster ophthalmicus in an AIDS patient: a case report. | 1996 | Cornea | pmid:8899277 |
| Okano H et al. | EM523L, a nonpeptide motilin agonist, stimulates gastric emptying and pancreatic polypeptide secretion. | 1996 | Peptides | pmid:8899806 |
| Guerrero-Lindner E et al. | Effect of motilin on gastrointestinal myoelectric activity in conscious rabbits. | 1996 | Peptides | pmid:8899807 |
| Flurer CL | Analysis of macrolide antibiotics by capillary electrophoresis. | 1996 | Electrophoresis | pmid:8900943 |
| Segreti J et al. | In vitro activity of macrolides against intracellular Legionella pneumophila. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8902407 |
| Wheeley MS | Erythromycin in renal failure. | 1977 | Br Med J | pmid:890394 |
| Kimani J et al. | Low dose erythromycin regimen for the treatment of chancroid. | 1995 | East Afr Med J | pmid:8904044 |
| Ohtomo T et al. | Effect of sub-inhibitory concentrations of clarithromycin and erythromycin on the production of Staphylococcus aureus capsules. | 1995 | J Chemother | pmid:8904089 |
| Perez-Ramos S et al. | Incidence of erythromycin resistance and penicillin resistance in clinical isolates of Streptococcus pneumoniae from a Spanish university hospital. | 1995 | J Chemother | pmid:8904113 |
| Mosca A et al. | Evaluation of the efficacy of josamycin in the treatment of impetigo in children and its in vitro activity on erythromycin resistant Staphylococcus aureus strains. | 1995 | J Chemother | pmid:8904141 |
| Yasui N | [The relationship between single-oral dose kinetics of alprazolam and cytochrome P4503A and cytochrome P4502C19]. | 1996 | Nihon Shinkei Seishin Yakurigaku Zasshi | pmid:8905799 |
| Hashiba M and Baba S | Efficacy of long-term administration of clarithromycin in the treatment of intractable chronic sinusitis. | 1996 | Acta Otolaryngol Suppl | pmid:8908275 |