erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Respiratory Insufficiency D012131 10 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Ischemia D007511 18 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Birth Weight D001724 23 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Hypertension D006973 115 associated lipids
Thromboembolism D013923 6 associated lipids
Periodontitis D010518 22 associated lipids
Dermatitis D003872 30 associated lipids
Nasal Polyps D009298 26 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Vomiting D014839 21 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Streptococcal Infections D013290 4 associated lipids
Otitis D010031 5 associated lipids
Cholelithiasis D002769 16 associated lipids
Fever D005334 35 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
Pneumococcal Infections D011008 7 associated lipids
Pneumonia D011014 10 associated lipids
Conjunctivitis D003231 7 associated lipids
Syphilis D013587 6 associated lipids
Chorioamnionitis D002821 5 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Hearing Disorders D006311 10 associated lipids
Duodenitis D004382 4 associated lipids
Death, Sudden D003645 12 associated lipids
Cardiomegaly D006332 31 associated lipids
Tachycardia D013610 7 associated lipids
Common Cold D003139 2 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Foot Diseases D005534 4 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Neutropenia D009503 15 associated lipids
Aortic Valve Stenosis D001024 4 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Urticaria D014581 13 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Leishmaniasis D007896 19 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
HIV Seropositivity D006679 15 associated lipids
Uveitis D014605 14 associated lipids
Surgical Wound Dehiscence D013529 3 associated lipids
Endophthalmitis D009877 12 associated lipids
Leprosy D007918 8 associated lipids
Laryngitis D007827 5 associated lipids
Cardiac Tamponade D002305 7 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Anemia, Hypochromic D000747 5 associated lipids
Dyspnea D004417 10 associated lipids
Listeriosis D008088 12 associated lipids
Periapical Diseases D010483 4 associated lipids
Tremor D014202 15 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Pemphigoid, Bullous D010391 8 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Hypothermia D007035 19 associated lipids
Orthomyxoviridae Infections D009976 3 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Hypoventilation D007040 2 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Paresthesia D010292 7 associated lipids
Pulmonary Emphysema D011656 3 associated lipids
Pleural Effusion D010996 3 associated lipids
Lipidoses D008064 7 associated lipids
Bronchopneumonia D001996 7 associated lipids
Pyoderma D011711 5 associated lipids
Lymphadenitis D008199 8 associated lipids
Drug Eruptions D003875 30 associated lipids
Folliculitis D005499 7 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Synovitis D013585 15 associated lipids
Cleft Palate D002972 9 associated lipids
Herpes Zoster Ophthalmicus D006563 2 associated lipids
Choline Deficiency D002796 16 associated lipids
Anemia, Hemolytic, Autoimmune D000744 5 associated lipids
Gangrene D005734 3 associated lipids
Toxoplasmosis, Animal D014124 5 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Campylobacter Infections D002169 13 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Bacteremia D016470 9 associated lipids
Arthralgia D018771 8 associated lipids
Nausea D009325 7 associated lipids
Prostatitis D011472 5 associated lipids
Factor X Deficiency D005171 2 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Stomatitis D013280 14 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Kuwahara T et al. Clinical characteristics and management of periesophageal vagal nerve injury complicating left atrial ablation of atrial fibrillation: lessons from eleven cases. 2013 J. Cardiovasc. Electrophysiol. pmid:23551640
Lozada LE et al. Development of pyloric stenosis after a 4-day course of oral erythromycin. 2013 Pediatr Emerg Care pmid:23558266
Herath SC and Poole P Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD). 2013 Cochrane Database Syst Rev pmid:24288145
Liang JH and Han X Structure-activity relationships and mechanism of action of macrolides derived from erythromycin as antibacterial agents. 2013 Curr Top Med Chem pmid:24200358
Matejcek A and Goldman RD Treatment and prevention of ophthalmia neonatorum. 2013 Can Fam Physician pmid:24235191
Kamal A et al. Anti-tubercular agents. Part 8: synthesis, antibacterial and antitubercular activity of 5-nitrofuran based 1,2,3-triazoles. 2013 Bioorg. Med. Chem. Lett. pmid:24206766
Rallis E et al. Topical 5% benzoyl peroxide and 3% erythromycin gel: experience with 191 patients with papulopustular acne. 2013 Acta Dermatovenerol Croat pmid:24183219
Sugino K et al. Granulomatous-lymphocytic interstitial lung disease in a patient with common variable immunodeficiency. 2013 Intern. Med. pmid:24292765
Goh S et al. Phage Ï•C2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains. 2013 MBio pmid:24255122
Ansari NN et al. Treatment of chronic rhinosinusitis using erythromycin phonophoresis. 2013 Physiother Theory Pract pmid:22891948
Chen DK et al. [Mechanism of hetero-erythromycin resistant Staphylococcus aureus and a comparison of detection methods]. 2013 Zhonghua Yi Xue Za Zhi pmid:24548451
Hennenberg M et al. The cAMP effector EPAC activates Elk1 transcription factor in prostate smooth muscle, and is a minor regulator of α1-adrenergic contraction. 2013 J. Biomed. Sci. pmid:23815815
Mu Y et al. Synergistic effects of anti-CmeA and anti-CmeB peptide nucleic acids on sensitizing Campylobacter jejuni to antibiotics. 2013 Antimicrob. Agents Chemother. pmid:23817373
González-Abad MJ and Alonso-Sanz M [Incidence and susceptibility of Campylobacter jejuni in pediatric patients: involvement in bacteremia]. 2013 Rev Esp Quimioter pmid:23817644
Sanz-Rodríguez N et al. [Accuracy of Etest method to study Campylobacter spp. susceptibility to erythromycin, ciprofloxacin and tetracycline]. 2013 Rev Esp Quimioter pmid:23817649
James GD et al. Use of long-term antibiotic treatment in COPD patients in the UK: a retrospective cohort study. 2013 Prim Care Respir J pmid:23839240
Parhi AK et al. Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. 2013 Bioorg. Med. Chem. Lett. pmid:23891185
Lee A Gastroparesis: what is the current state-of-the-art for evaluation and medical management? What are the results? 2013 J. Gastrointest. Surg. pmid:23801519
Mu X et al. Effects of erythromycin and rifampicin on immunomodulatory gene expression and cellular function in human polymorphonuclear leukocytes. 2013 Chemotherapy pmid:24852442
Wittwer MB et al. Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. 2013 J. Med. Chem. pmid:23241029
Berger A et al. Two cases of cutaneous diphtheria associated with occupational pig contact in Germany. 2013 Zoonoses Public Health pmid:23280311
Juntunen P et al. Absence of tetracycline resistance in Campylobacter coli isolates from Finnish finishing pigs treated with chlortetracycline. 2013 J. Appl. Microbiol. pmid:23282197
Mavri A and Smole Možina S Resistance to bile salts and sodium deoxycholate in macrolide- and fluoroquinolone-susceptible and resistant Campylobacter jejuni and Campylobacter coli strains. 2013 Microb. Drug Resist. pmid:23289436
Lin KJ et al. Safety of macrolides during pregnancy. 2013 Am. J. Obstet. Gynecol. pmid:23254249
Sánchez Valenzuela A et al. Phenotypic and molecular antibiotic resistance profile of Enterococcus faecalis and Enterococcus faecium isolated from different traditional fermented foods. 2013 Foodborne Pathog. Dis. pmid:23259502
Sanad YM et al. Molecular epidemiology and public health relevance of Campylobacter isolated from dairy cattle and European starlings in Ohio, USA. 2013 Foodborne Pathog. Dis. pmid:23259503
Haruna M et al. Prevalence and antimicrobial resistance of Campylobacter isolates from beef cattle and pigs in Japan. 2013 J. Vet. Med. Sci. pmid:23220905
Javid FA et al. Anti-emetic and emetic effects of erythromycin in Suncus murinus: role of vagal nerve activation, gastric motility stimulation and motilin receptors. 2013 Eur. J. Pharmacol. pmid:23201066
Osterman IA et al. A nascent proteome study combining click chemistry with 2DE. 2013 Proteomics pmid:23161590
Metzler K et al. Minimal inhibitory and mutant prevention concentrations of azithromycin, clarithromycin and erythromycin for clinical isolates of Streptococcus pneumoniae. 2013 J. Antimicrob. Chemother. pmid:23169894
Akiyoshi T et al. Mechanism-based inhibition profiles of erythromycin and clarithromycin with cytochrome P450 3A4 genetic variants. 2013 Drug Metab. Pharmacokinet. pmid:23514827
Müller W et al. German Francisella tularensis isolates from European brown hares (Lepus europaeus) reveal genetic and phenotypic diversity. 2013 BMC Microbiol. pmid:23517149
Lasnier O et al. Two cases of corneal abrasions in children exposed to liquid detergent capsules. 2013 Can. J. Ophthalmol. pmid:23561618
Methicillin resistant Staphylococcus aureus (MRSA) in India: prevalence & susceptibility pattern. 2013 Indian J. Med. Res. pmid:23563381
Rogers GB et al. Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition. 2013 Thorax pmid:23564400
Litvinchuk AV et al. Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. 2013 Apr-May Eur. J. Cell Biol. pmid:23523087
Lynch M et al. Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. 2013 Jan-Feb Pediatr Dermatol pmid:23316718
Jiang M et al. Improved heterologous erythromycin A production through expression plasmid re-design. 2013 Jul-Aug Biotechnol. Prog. pmid:23804312
Zou X et al. Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. 2013 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:23795479
De Alwis HG et al. Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. 2013 Nov-Dec J AOAC Int pmid:24645499
Kim S and Muthusamy VR Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. 2013 Sep-Oct Saudi J Gastroenterol pmid:24045591
Theivanayagam S et al. Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. 2013 Sep-Oct Saudi J Gastroenterol pmid:24045593
Manchia M et al. Repeated erythromycin/codeine-induced psychotic mania. 2013 Sep-Oct Clin Neuropharmacol pmid:24045612
Chen D et al. Identification and characterization of a new erythromycin biosynthetic gene cluster in Actinopolyspora erythraea YIM90600, a novel erythronolide-producing halophilic actinomycete isolated from salt field. 2014 PLoS ONE pmid:25250723
Sadeghi J and Mansouri S Molecular characterization and antibiotic resistance of clinical isolates of methicillin-resistant Staphylococcus aureus obtained from Southeast of Iran (Kerman). 2014 APMIS pmid:24033803
Blattner C et al. A case of bacillary angiomatosis in a patient with pancreatic adenocarcinoma. 2014 J. Cutan. Pathol. pmid:24588271
Brenciani A et al. ICESp1116, the genetic element responsible for erm(B)-mediated, inducible erythromycin resistance in Streptococcus pyogenes, belongs to the TnGBS family of integrative and conjugative elements. 2014 Antimicrob. Agents Chemother. pmid:24449773
Yu ZC et al. Development of a genetic system for the deep-sea psychrophilic bacterium Pseudoalteromonas sp. SM9913. 2014 Microb. Cell Fact. pmid:24450434
Barnes P and Chauhan M Chancroid - desperate patient makes own diagnosis. 2014 Int J STD AIDS pmid:24535694
Wang S et al. Comparison of microbial communities in sequencing batch reactors (SBRs) exposed to trace erythromycin and erythromycin-Hâ‚‚O. 2014 Appl. Microbiol. Biotechnol. pmid:24072160
Barbosa TM et al. A novel erythromycin resistance plasmid from Bacillus sp. strain HS24, isolated from the marine sponge Haliclona simulans. 2014 PLoS ONE pmid:25548909
Liao D et al. Quantitative differences between primary and secondary peristaltic contractions of the esophagus. 2014 Dig. Dis. Sci. pmid:24682721
Hudson BH and Zaher HS Ribosomes left in the dust: diverse strategies for Peptide-mediated translation stalling. 2014 Mol. Cell pmid:25514181
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Katayama Y et al. Neuroprotective effects of erythromycin on cerebral ischemia reperfusion-injury and cell viability after oxygen-glucose deprivation in cultured neuronal cells. 2014 Brain Res. pmid:25264351
Bauer CA and Grimme S First principles calculation of electron ionization mass spectra for selected organic drug molecules. 2014 Org. Biomol. Chem. pmid:25260171
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Ziupa D et al. Pronounced effects of HERG-blockers E-4031 and erythromycin on APD, spatial APD dispersion and triangulation in transgenic long-QT type 1 rabbits. 2014 PLoS ONE pmid:25244401
Westerhof J et al. Completion rate of small bowel capsule endoscopy is higher after erythromycin compared to domperidone. 2014 BMC Gastroenterol pmid:25234278
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Shen Y et al. Mitigative effect of erythromycin on PMMA challenged preosteoblastic MC3T3-E1 cells. 2014 ScientificWorldJournal pmid:25110723
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Flamm RK et al. Antimicrobial activity of ceftaroline tested against drug-resistant subsets of Streptococcus pneumoniae from U.S. medical centers. 2014 Antimicrob. Agents Chemother. pmid:24514082
Sahu AK et al. Formulation optimization of erythromycin solid lipid nanocarrier using response surface methodology. 2014 Biomed Res Int pmid:25045692
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Kawaguchiya M et al. Serotype distribution and susceptibility to penicillin and erythromycin among noninvasive or colonization isolates of Streptococcus pneumoniae in northern Japan: a cross-sectional study in the pre-PCV7 routine immunization period. 2014 Microb. Drug Resist. pmid:24766085
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Boleda MR et al. Survey of the occurrence of pharmaceuticals in Spanish finished drinking waters. 2014 Environ Sci Pollut Res Int pmid:24756682
Nilsson MF and Webster WS Effects of macrolide antibiotics on rat embryonic heart function in vitro. 2014 Birth Defects Res. B Dev. Reprod. Toxicol. pmid:24753334
Murphree CA et al. Antibiotic resistance among cultured bacterial isolates from bioethanol fermentation facilities across the United States. 2014 Curr. Microbiol. pmid:24748439
Sakamoto N et al. Bronchiolitis in a patient with ulcerative colitis treated with erythromycin. 2014 Intern. Med. pmid:24739609
Szemraj M et al. Macrolide, lincosamide, and streptogramin B resistance in lipophilic Corynebacteria inhabiting healthy human skin. 2014 Microb. Drug Resist. pmid:24735183
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Yosida M et al. Involvement of cAMP/EPAC/TRPM2 activation in glucose- and incretin-induced insulin secretion. 2014 Diabetes pmid:24824430
Hellmann-Regen J et al. Do tetracyclines and erythromycin exert anti-acne effects by inhibition of P450-mediated degradation of retinoic acid? 2014 Exp. Dermatol. pmid:24690039
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Xu J et al. Phenotypic and genotypic antimicrobial resistance traits of foodborne Staphylococcus aureus isolates from Shanghai. 2014 J. Food Sci. pmid:24689704
Wang D et al. Structural and environmental features of novel mdfA variant and mdfA genes in recombinant regions of Escherichia coli. 2014 Microb. Drug Resist. pmid:24684286
Zheng PX et al. Arrangement and number of clustered regularly interspaced short palindromic repeat spacers are associated with erythromycin susceptibility in emm12, emm75 and emm92 of group A streptococcus. 2014 Clin. Microbiol. Infect. pmid:24118239
Singh P et al. Erythromycin-induced genotoxicity and hepatotoxicity in mice pups treated during prenatal and postnatal period. 2014 Fundam Clin Pharmacol pmid:24117516
Dalbøge CS et al. Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. 2014 J. Cyst. Fibros. pmid:24035278
Di Salvo A et al. Pharmacokinetics and residue depletion of erythromycin in gilthead sea bream Sparus aurata L. after oral administration. 2014 J. Fish Dis. pmid:23992037