erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Minas W et al. | Improved erythromycin production in a genetically engineered industrial strain of Saccharopolyspora erythraea. | 1998 Jul-Aug | Biotechnol. Prog. | pmid:9694676 |
| Tohyama J et al. | [A case of Sanfilippo syndrome type C: long-term clinical course and treatment]. | 1998 | No To Hattatsu | pmid:9695627 |
| Woo EK et al. | Multiple antibiotic resistance in Streptococcus pneumoniae. | 1998 | Med. J. Aust. | pmid:9695709 |
| Wagner D | CYP3A4 and the erythromycin breath test. | 1998 | Clin. Pharmacol. Ther. | pmid:9695728 |
| Pearlman MD et al. | Frequent resistance of clinical group B streptococci isolates to clindamycin and erythromycin. | 1998 | Obstet Gynecol | pmid:9699763 |
| Takizawa H et al. | Erythromycin and clarithromycin attenuate cytokine-induced endothelin-1 expression in human bronchial epithelial cells. | 1998 | Eur. Respir. J. | pmid:9701415 |
| Takamori M et al. | [A case of legionnaire's disease due to Legionella pneumophila serogroup 6]. | 1998 | Nippon Naika Gakkai Zasshi | pmid:9702025 |
| Doherty TJ et al. | Acetaminophen as a marker of gastric emptying in ponies. | 1998 | Equine Vet. J. | pmid:9705120 |
| Cornaglia G et al. | Resistance of Streptococcus pyogenes to erythromycin and related antibiotics in Italy. The Italian Surveillance Group for Antimicrobial Resistance. | 1998 | Clin. Infect. Dis. | pmid:9710676 |
| Rowe CJ et al. | Construction of new vectors for high-level expression in actinomycetes. | 1998 | Gene | pmid:9714812 |
| Kent S et al. | T wave alternans associated with HIV cardiomyopathy, erythromycin therapy, and electrolyte disturbances. | 1998 | South. Med. J. | pmid:9715223 |
| Korting HC et al. | Current antimicrobial susceptibility of cutaneous bacteria to first line antibiotics. | 1998 | Int. J. Antimicrob. Agents | pmid:9716294 |
| Faghih R et al. | Synthesis of 9-deoxo-4''-deoxy-6,9-epoxyerythromycin derivatives: novel and acid-stable motilides. | 1998 | J. Med. Chem. | pmid:9719592 |
| Reeves AR et al. | Physical-genetic map of the erythromycin-producing organism Saccharopolyspora erythraea. | 1998 | Microbiology (Reading, Engl.) | pmid:9720036 |
| Kessie G et al. | Plasmid profile and antibiotic resistance in coagulase-negative staphylococci isolated from polluted water. | 1998 | J. Appl. Microbiol. | pmid:9721646 |
| Paul VK et al. | Erythromycin treatment of pregnant women to reduce the incidence of low birth weight and preterm deliveries. | 1998 | Int J Gynaecol Obstet | pmid:9722132 |
| Colsky AS et al. | Analysis of antibiotic susceptibilities of skin wound flora in hospitalized dermatology patients. The crisis of antibiotic resistance has come to the surface. | 1998 | Arch Dermatol | pmid:9722732 |
| Kuo WH et al. | Cephalosporin antibiotics accelerate gastric emptying in mice. | 1998 | Dig. Dis. Sci. | pmid:9724153 |
| Wang RF et al. | Molecular identification of a Stenotrophomonas species used in the bioassay for erythromycin in aquaculture samples. | 1998 | Mol. Cell. Probes | pmid:9727203 |
| Tang CM and Macfarlane JT | Early management of younger adults dying of community acquired pneumonia. | 1993 | Respir Med | pmid:9728229 |
| Varga J and Fodor L | Biochemical characteristics, serogroup distribution, antibiotic susceptibility and age-related significance of Campylobacter strains causing diarrhoea in humans in Hungary. | 1998 | Zentralbl. Bakteriol. | pmid:9728406 |
| Kantola T et al. | Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations. | 1998 | Clin. Pharmacol. Ther. | pmid:9728898 |
| Edelstein PH | Antimicrobial chemotherapy for Legionnaires disease: time for a change. | 1998 | Ann. Intern. Med. | pmid:9729189 |
| Xu QW et al. | Effect of the prokinetic agent, erythromycin, in the Richardson ground squirrel model of cholesterol gallstone disease. | 1998 | Hepatology | pmid:9731548 |
| Eckardt L et al. | Drug-related torsades de pointes in the isolated rabbit heart: comparison of clofilium, d,l-sotalol, and erythromycin. | 1998 | J. Cardiovasc. Pharmacol. | pmid:9733356 |
| McDougal LK et al. | Detection of Tn917-like sequences within a Tn916-like conjugative transposon (Tn3872) in erythromycin-resistant isolates of Streptococcus pneumoniae. | 1998 | Antimicrob. Agents Chemother. | pmid:9736555 |
| Koch CL et al. | In-vitro antibiotic susceptibility and molecular analysis of anaerobic bacteria isolated in Cape Town, South Africa. | 1998 | J. Antimicrob. Chemother. | pmid:9738844 |
| Barg N | Comparison of four antibiotics in a murine model of necrotizing cutaneous infections caused by toxigenic Streptococcus pyogenes and Staphylococcus aureus. | 1998 | J. Antimicrob. Chemother. | pmid:9738847 |
| Hargreaves CA et al. | Effects of co-trimoxazole, erythromycin, amoxycillin, tetracycline and chloroquine on sperm function in vitro. | 1998 | Hum. Reprod. | pmid:9740442 |
| Tsang KW et al. | Clinical profiles of Chinese patients with diffuse panbronchiolitis. | 1998 | Thorax | pmid:9741370 |
| Somkuti GA et al. | Molecular characterization of the erythromycin resistance plasmid pPV142 from Staphylococcus simulans. | 1998 | FEMS Microbiol. Lett. | pmid:9742700 |
| Igari J et al. | [Antimicrobial activities of roxithromycin against recently obtained clinical isolates]. | 1997 | Jpn J Antibiot | pmid:9743909 |
| Hamáková K and Danda J | [Treatment of syphilis with other antibiotics than penicillin (author's transl)]. | 1976 | Cesk Dermatol | pmid:975270 |
| Esposito S et al. | Erythromycin resistance in group A beta hemolytic streptococcus. | 1998 Nov-Dec | Chemotherapy | pmid:9755297 |
| Greenblatt DJ et al. | Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences. | 1998 | Clin. Pharmacol. Ther. | pmid:9757151 |
| Barbanoj MJ et al. | Buspirone plasma concentrations. | 1998 | Clin. Pharmacol. Ther. | pmid:9757159 |
| Hoppe JE and Paulus T | Comparison of three media for agar dilution susceptibility testing of Bordetella pertussis using six antibiotics. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9758277 |
| GarcÃa-de-Lomas J et al. | A comparative study on the efficacy of the new quinolone alatrofloxacin in the treatment of experimental legionellosis in guinea pigs. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9758285 |
| Nion I et al. | [Role of intravenous erythromycin in the preparation for endoscopy in case of upper digestive hemorrhage]. | 1998 | Gastroenterol. Clin. Biol. | pmid:9762296 |
| Gené A et al. | [Antibiotic sensitivity of Streptococcus pyogenes in pediatrics]. | 1998 Jun-Jul | Enferm. Infecc. Microbiol. Clin. | pmid:9763744 |
| Agouridas C et al. | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. | 1998 | J. Med. Chem. | pmid:9767644 |
| Vizel' AA et al. | [Antibiotic sensitivity of pathogenic microflora: data of the bacteriological laboratory at the antituberculosis clinic]. | 1998 | Probl Tuberk | pmid:9771042 |
| Rosenthal SL and Freundlich LF | In vitro antibiotic sensitivity of Pasteurella multocida. | 1976 | Health Lab Sci | pmid:977341 |
| Leroyer C et al. | Dirithromycin concentrations in bronchial mucosa and secretions. | 1998 | Respiration | pmid:9782221 |
| Brünker P et al. | Genetic engineering of an industrial strain of Saccharopolyspora erythraea for stable expression of the Vitreoscilla haemoglobin gene (vhb). | 1998 | Microbiology (Reading, Engl.) | pmid:9782491 |
| Jacobsen JR et al. | Precursor-directed biosynthesis of 12-ethyl erythromycin. | 1998 | Bioorg. Med. Chem. | pmid:9784859 |
| Yanagisawa M et al. | [Effective treatment in combination with erythromycin and cisapride for chronic idiopathic intestinal pseudo-obstruction (CIIP)]. | 1998 | Nihon Shokakibyo Gakkai Zasshi | pmid:9785893 |
| Cimolai N | Mycoplasma pneumoniae respiratory infection. | 1998 | Pediatr Rev | pmid:9785929 |
| Schülin T et al. | In-vitro activity of the new ketolide antibiotic HMR 3647 against gram-positive bacteria. | 1998 | J. Antimicrob. Chemother. | pmid:9786468 |
| Saenko VF et al. | [The influence of macrolides on the motor function of the gastrointestinal duct]. | 1998 | Klin Khir | pmid:9787571 |
| Klimchuk ND | [The effect of various antibiotics on the formation of typhus antibodies following immunization with typhus vaccine]. | 1978 | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:97881 |
| Geslin P et al. | [Development of resistance to beta-lactams and other antibiotics of pneumococci isolated from acute otitis media in France: statement of the National Reference Center 1995-1996]. | 1998 | Arch Pediatr | pmid:9789629 |
| Oh TG et al. | Induction of ermAMR from a clinical strain of Enterococcus faecalis by 16-membered-ring macrolide antibiotics. | 1998 | J. Bacteriol. | pmid:9791136 |
| Kolpakov AI et al. | [Use of exogenous ribonuclease for improvement of Lactobacillus biological properties]. | 1998 | Antibiot. Khimioter. | pmid:9791680 |
| Platonova MM et al. | [Clinical significance of fungal and microbial associations and antibacterial therapy for treatment of chronic inflammatory respiratory tract diseases in children]. | 1998 | Antibiot. Khimioter. | pmid:9791682 |
| Danias PG et al. | Comparative in vitro and in vivo efficacy of roxithromycin and erythromycin against a strain of methicillin-susceptible Staphylococcus epidermidis. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9791758 |
| Riippi M et al. | Dependence between dissolution rate and porosity of compressed erythromycin acistrate tablets. | 1998 | Eur J Pharm Biopharm | pmid:9795044 |
| Bellido JL et al. | [Resistance to macrolides in Streptococcus pyogenes]. | 1998 | Rev Esp Quimioter | pmid:9795305 |
| Limia A et al. | [Phenotypic characterization of erythromycin resistance in strains of the genus Streptococcus isolated from clinical specimens]. | 1998 | Rev Esp Quimioter | pmid:9795307 |
| Recommended treatment schedules for syphilis. | 1976 | Med Times | pmid:979578 | |
| Yamaguchi K et al. | [Legionella pneumonia--epidemiology, clinical characteristics and development of diagnosis]. | 1998 | Nippon Rinsho | pmid:9796341 |
| Piccolomini R et al. | Bacteriostatic and bactericidal in vitro activities of clarithromycin and erythromycin against periodontopathic Actinobacillus actinomycetemcomitans. | 1998 | Antimicrob. Agents Chemother. | pmid:9797240 |
| Tunney MM et al. | Antimicrobial susceptibility of bacteria isolated from orthopedic implants following revision hip surgery. | 1998 | Antimicrob. Agents Chemother. | pmid:9797241 |
| Nicola FG et al. | Characterization of erythromycin-resistant isolates of Staphylococcus aureus recovered in the United States from 1958 through 1969. | 1998 | Antimicrob. Agents Chemother. | pmid:9797248 |
| Kneen R et al. | Penicillin vs. erythromycin in the treatment of diphtheria. | 1998 | Clin. Infect. Dis. | pmid:9798043 |
| Harris JA et al. | Safety and efficacy of azithromycin in the treatment of community-acquired pneumonia in children. | 1998 | Pediatr. Infect. Dis. J. | pmid:9802626 |
| Levin S and Jupa JE | Principles of antibiotic usage in obstetrics and gynecology. | 1976 | Obstet Gynecol Annu | pmid:980275 |
| Kisch AL | Principles of the antimicrobial therapy of head and neck infections. | 1976 | Otolaryngol. Clin. North Am. | pmid:980506 |
| Kondo M et al. | Erythromycin inhibits ATP-induced intracellular calcium responses in bovine tracheal epithelial cells. | 1998 | Am. J. Respir. Cell Mol. Biol. | pmid:9806744 |
| Sanchez R | A medium-copy-number plasmid for insertional mutagenesis of Streptococcus mutans. | 1998 | Plasmid | pmid:9806863 |
| Yamazaki H and Shimada T | Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin. | 1998 | Drug Metab. Dispos. | pmid:9806945 |
| Champney WS and Tober CL | Inhibition of translation and 50S ribosomal subunit formation in Staphylococcus aureus cells by 11 different ketolide antibiotics. | 1998 | Curr. Microbiol. | pmid:9806981 |
| Nakazawa Y et al. | Relationship between in vivo FK506 clearance and in vitro 13-demethylation activity in living-related liver transplantation. | 1998 | Transplantation | pmid:9808496 |
| Tanaka T et al. | Effects of EM574 and cisapride on gastric contractile and emptying activity in normal and drug-induced gastroparesis in dogs. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9808701 |
| Taniguchi K et al. | Identification of Escherichia coli clinical isolates producing macrolide 2'-phosphotransferase by a highly sensitive detection method. | 1998 | FEMS Microbiol. Lett. | pmid:9809420 |
| Villar D et al. | Novobiocin inhibits both UDP-glucuronosyltransferase and cytochrome P450-mediated enzyme activities in pig liver microsomes. | 1998 | Vet. Res. Commun. | pmid:9810637 |
| Kaufhold A and Klein R | Species identification and antibiotic susceptibility of enterococci isolated from clinical specimens of hospitalized patients. | 1995 | Zentralbl. Bakteriol. | pmid:9810675 |
| Nizami SQ and Farooqui BJ | Cholera in children in Karachi from 1990 through 1995: a study of cases admitted to a tertiary care hospital. | 1998 | J Pak Med Assoc | pmid:9813989 |
| Champney WS and Burdine R | Macrolide antibiotic inhibition of translation and 50S ribosomal subunit assembly in methicillin-resistant Staphylococcus aureus cells. | 1998 | Microb. Drug Resist. | pmid:9818968 |
| Udo EE and Jacob LE | Conjugative transfer of high-level mupirocin resistance and the mobilization of non-conjugative plasmids in Staphylococcus aureus. | 1998 | Microb. Drug Resist. | pmid:9818970 |
| Lazarevski G et al. | Acid catalyzed ring opening reactions of 6-deoxy-9-deoxo-9a-aza-9a-homo-erythromycin A 6,9-cyclic imino ether. | 1998 | J. Antibiot. | pmid:9820243 |
| Takano M et al. | Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells. | 1998 | Eur. J. Pharmacol. | pmid:9822896 |
| Moffitt CM | Field trials of investigational new animal drugs. | 1998 | Vet Hum Toxicol | pmid:9823586 |
| Su BH et al. | Effect of erythromycin on feeding intolerance in very low birth weight infants: a preliminary observation. | 1998 Sep-Oct | Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi | pmid:9823678 |
| Xu QW et al. | Altered migrating myoelectrical complex in an animal model of cholesterol gallstone disease: the effect of erythromycin. | 1998 | Gut | pmid:9824610 |
| Thomsen MS et al. | Lack of pharmacokinetic interaction between tiagabine and erythromycin. | 1998 | J Clin Pharmacol | pmid:9824787 |
| Jónsson B et al. | Ureaplasma urealyticum, erythromycin and respiratory morbidity in high-risk preterm neonates. | 1998 | Acta Paediatr. | pmid:9825977 |
| Larsen B and Glover DD | Serum erythromycin levels in pregnancy. | 1998 Sep-Oct | Clin Ther | pmid:9829448 |
| Sato K et al. | Comparison of the anticoagulant and antithrombotic effects of YM-75466, a novel orally-active factor Xa inhibitor, and warfarin in mice. | 1998 | Jpn. J. Pharmacol. | pmid:9829622 |
| Woodhead M | Community acquired pneumonia in elderly people. Addition of erythromycin is not currently justified. | 1998 | BMJ | pmid:9831595 |
| Reinert RR et al. | In vitro activity of quinupristin/dalfopristin against erythromycin-susceptible and erythromycin-resistant Streptococcus pneumoniae. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9832271 |
| Isohanni MH et al. | Effect of erythromycin and itraconazole on the pharmacokinetics of intravenous lignocaine. | 1998 | Eur. J. Clin. Pharmacol. | pmid:9832299 |
| Khiat A and Boulanger Y | Identification of the motilide pharmacophores using quantitative structure activity relationships. | 1998 | J. Pept. Res. | pmid:9832311 |
| Nissan A et al. | Direct inhibitory effect of erythromycin on the gallbladder muscle. | 1997 Jul-Aug | J. Gastrointest. Surg. | pmid:9834366 |
| Baltch AL et al. | Antibacterial effects of levofloxacin, erythromycin, and rifampin in a human monocyte system against Legionella pneumophila. | 1998 | Antimicrob. Agents Chemother. | pmid:9835507 |
| Berry V et al. | Bacteriological efficacies of three macrolides compared with those of amoxicillin-clavulanate against Streptococcus pneumoniae and Haemophilus influenzae. | 1998 | Antimicrob. Agents Chemother. | pmid:9835514 |
| Torres C et al. | In vitro activity of the new ketolide HMR3647 in comparison with those of macrolides and pristinamycins against Enterococcus spp. | 1998 | Antimicrob. Agents Chemother. | pmid:9835527 |
| Emond E et al. | AbiQ, an abortive infection mechanism from Lactococcus lactis. | 1998 | Appl. Environ. Microbiol. | pmid:9835558 |
| Kinashi H et al. | Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9836424 |
| Koh TH et al. | Molecular typing of multiresistant Streptococcus pneumoniae serogroup 19 in Singapore. | 1998 | Pathology | pmid:9839316 |