erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Zhou D and Apicella MA | Plasmids with erythromycin resistance and catechol 2,3-dioxygenase- or beta-galactosidase-encoding gene cassettes for use in Neisseria spp. | 1996 | Gene | pmid:8675023 |
Surrenti E et al. | Antral axial forces postprandially and after erythromycin in organic and functional dysmotilities. | 1996 | Dig. Dis. Sci. | pmid:8674390 |
Nikulin KG | [Treatment of acute pneumonia at different stages of the disease]. | 1977 | Ter. Arkh. | pmid:867244 |
McMeekin TO and Moschella SL | Iatrogenic complications of dermatologic therapy. Primum non nocere. | 1979 | Med. Clin. North Am. | pmid:86664 |
Lode H et al. | Treatment of community-acquired pneumonia: a randomized comparison of sparfloxacin, amoxycillin-clavulanic acid and erythromycin. | 1995 | Eur. Respir. J. | pmid:8666093 |
Johnson AP et al. | Prevalence of antibiotic resistance and serotypes in pneumococci in England and Wales: results of observational surveys in 1990 and 1995. | 1996 | BMJ | pmid:8664623 |
Aleksandrova AE and Vinogradova TI | [Immunotropic activity of antimicrobial agents used in tuberculosis]. | 1996 | Probl Tuberk | pmid:8657696 |
King DE et al. | Effectiveness of erythromycin in the treatment of acute bronchitis. | 1996 | J Fam Pract | pmid:8656171 |
Packman AM et al. | Treatment of acne vulgaris: combination of 3% erythromycin and 5% benzoyl peroxide in a gel compared to clindamycin phosphate lotion. | 1996 | Int. J. Dermatol. | pmid:8655242 |
Kligman AM | The treatment of acne. Part III: antibacterials. | 1995 | Cutis | pmid:8654122 |
Mashkilleyson AL et al. | Treatment of syphilis with azithromycin. | 1996 | Int J STD AIDS | pmid:8652720 |
Pieper R et al. | Erythromycin biosynthesis: kinetic studies on a fully active modular polyketide synthase using natural and unnatural substrates. | 1996 | Biochemistry | pmid:8652546 |
Vickery CL et al. | Bacillary angiomatosis presenting as a nasal mass with epistaxis. | 1996 | Otolaryngol Head Neck Surg | pmid:8649879 |
Dam M et al. | Mutations in domain II of 23 S rRNA facilitate translation of a 23 S rRNA-encoded pentapeptide conferring erythromycin resistance. | 1996 | J. Mol. Biol. | pmid:8648637 |
Yasui N et al. | A kinetic and dynamic study of oral alprazolam with and without erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in alprazolam metabolism. | 1996 | Clin. Pharmacol. Ther. | pmid:8646822 |
Belousov IuB et al. | [Dirithromycin in the treatment of infections of the lower respiratory tract]. | 1995 | Antibiot. Khimioter. | pmid:8645058 |
Tenson T et al. | A functional peptide encoded in the Escherichia coli 23S rRNA. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8643630 |
Gerber MA | Antibiotic resistance: relationship to persistence of group A streptococci in the upper respiratory tract. | 1996 | Pediatrics | pmid:8637784 |
Stopler T et al. | [Mycoplasma pneumoniae infections in families in Jerusalem and in kibbutzim]. | 1977 | Harefuah | pmid:863299 |
Fang CC et al. | Erythromycin-induced acute pancreatitis. | 1996 | J. Toxicol. Clin. Toxicol. | pmid:8632521 |
Cohen LG et al. | Erythromycin-induced clozapine toxic reaction. | 1996 | Arch. Intern. Med. | pmid:8629881 |
Huang XM et al. | Base decomposition of erythromycin A methoxime. | 1996 | J. Antibiot. | pmid:8626251 |
Plaza MA et al. | Effect of motilin, somatostatin and bombesin on gastroduodenal myoelectric activity in sheep. | 1996 | Life Sci. | pmid:8622567 |
Noguchi N et al. | Nucleotide sequence and characterization of erythromycin resistance determinant that encodes macrolide 2'-phosphotransferase I in Escherichia coli. | 1995 | Antimicrob. Agents Chemother. | pmid:8619599 |
Hsueh PR et al. | Decreased activity of erythromycin against Streptococcus pyogenes in Taiwan. | 1995 | Antimicrob. Agents Chemother. | pmid:8619575 |
Miller RD and Fung DY | The excretion of enterotoxin B from nongrowing cells of Staphylococcus aureus 4916. | 1977 | Can. J. Microbiol. | pmid:861845 |
Tzovaras G et al. | The effect of intravenous erythromycin on esophageal motility in healthy subjects. | 1996 | Am. J. Surg. | pmid:8615464 |
Blumenfeld H et al. | Trimethoprim and sulfonamide-associated meningoencephalitis with MRI correlates. | 1996 | Neurology | pmid:8614533 |
Thompson D and Oster G | Use of terfenadine and contraindicated drugs. | 1996 | JAMA | pmid:8614120 |
Harris RZ et al. | The effects of menopause and hormone replacement therapies on prednisolone and erythromycin pharmacokinetics. | 1996 | Clin. Pharmacol. Ther. | pmid:8612388 |
Feierman DE | Identification of cytochrome P450 3A1/2 as the major P450 isoform responsible for the metabolism of fentanyl by rat liver microsomes. | 1996 | Anesth. Analg. | pmid:8610902 |
Kadota J et al. | Significance of IL-1beta and IL-1 receptor antagonist (IL-1Ra) in bronchoalveolar lavage fluid (BALF) in patients with diffuse panbronchiolitis (DPB). | 1996 | Clin. Exp. Immunol. | pmid:8608647 |
Oberg KC and Bauman JL | QT interval prolongation and torsades de pointes due to erythromycin lactobionate. | 1995 Nov-Dec | Pharmacotherapy | pmid:8602374 |
Avila-Campos MJ et al. | Distribution of biotypes and antimicrobial susceptibility of Actinobacillus actinomycetemcomitans. | 1995 | Oral Microbiol. Immunol. | pmid:8602348 |
Burt M et al. | Erythromycin stimulates gastric emptying after esophagectomy with gastric replacement: a randomized clinical trial. | 1996 | J. Thorac. Cardiovasc. Surg. | pmid:8601981 |
Westh H | Erythromycin-resistant Staphylococcus aureus in Denmark. | 1996 | APMIS Suppl. | pmid:8600946 |
The choice of antibacterial drugs. | 1996 | Med Lett Drugs Ther | pmid:8598824 | |
Schachter J and Dawson CR | Is trachoma an ocular component of a more generalised chlamydial infection? | 1979 | Lancet | pmid:85939 |
Vasilos LV et al. | [Chemotherapeutic effectiveness of erythromycin, rifampicin and tetracyclines in chlamydiosis and mycoplasmosis in children]. | 1995 | Antibiot. Khimioter. | pmid:8593094 |
Lucier TS et al. | Transition mutations in the 23S rRNA of erythromycin-resistant isolates of Mycoplasma pneumoniae. | 1995 | Antimicrob. Agents Chemother. | pmid:8593017 |
Bental T et al. | Chronic Q fever of pregnancy presenting as Coxiella burnetii placentitis: successful outcome following therapy with erythromycin and rifampin. | 1995 | Clin. Infect. Dis. | pmid:8589167 |
Lavy E et al. | Minimal inhibitory concentrations for canine isolates and oral absorption of roxythromycin in fed and fasted dogs. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8587159 |
Radulovic S et al. | In vitro and in vivo antibiotic susceptibilities of ELB rickettsiae. | 1995 | Antimicrob. Agents Chemother. | pmid:8585746 |
Hamzehpour MM et al. | OprK and OprM define two genetically distinct multidrug efflux systems in Pseudomonas aeruginosa. | 1995 | Antimicrob. Agents Chemother. | pmid:8585714 |
De Serres G et al. | Field effectiveness of erythromycin prophylaxis to prevent pertussis within families. | 1995 | Pediatr. Infect. Dis. J. | pmid:8584364 |
Bortolussi R et al. | Clinical course of pertussis in immunized children. | 1995 | Pediatr. Infect. Dis. J. | pmid:8584314 |
Tinanoff N et al. | Dental treatment of Papillon-Lefèvre syndrome: 15-year follow-up. | 1995 | J. Clin. Periodontol. | pmid:8583017 |
Minocha A et al. | Erythromycin shortens orocaecal transit time in diabetic male subjects: a double-blind placebo-controlled study. | 1995 | Aliment. Pharmacol. Ther. | pmid:8580273 |
Slomiany BL et al. | Sucralfate affects the susceptibility of Helicobacter pylori to antimicrobial agents. | 1995 | Scand. J. Gastroenterol. Suppl. | pmid:8578215 |
Masclee AA et al. | Effect of antrectomy and truncal vagotomy on erythromycin induced pancreatic polypeptide secretion. | 1995 | Regul. Pept. | pmid:8577928 |