erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Respiratory Insufficiency D012131 10 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Ischemia D007511 18 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Birth Weight D001724 23 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Hypertension D006973 115 associated lipids
Thromboembolism D013923 6 associated lipids
Periodontitis D010518 22 associated lipids
Dermatitis D003872 30 associated lipids
Nasal Polyps D009298 26 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Vomiting D014839 21 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Streptococcal Infections D013290 4 associated lipids
Otitis D010031 5 associated lipids
Cholelithiasis D002769 16 associated lipids
Fever D005334 35 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
Pneumococcal Infections D011008 7 associated lipids
Pneumonia D011014 10 associated lipids
Conjunctivitis D003231 7 associated lipids
Syphilis D013587 6 associated lipids
Chorioamnionitis D002821 5 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Hearing Disorders D006311 10 associated lipids
Duodenitis D004382 4 associated lipids
Death, Sudden D003645 12 associated lipids
Cardiomegaly D006332 31 associated lipids
Tachycardia D013610 7 associated lipids
Common Cold D003139 2 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Foot Diseases D005534 4 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Neutropenia D009503 15 associated lipids
Aortic Valve Stenosis D001024 4 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Urticaria D014581 13 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Leishmaniasis D007896 19 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
HIV Seropositivity D006679 15 associated lipids
Uveitis D014605 14 associated lipids
Surgical Wound Dehiscence D013529 3 associated lipids
Endophthalmitis D009877 12 associated lipids
Leprosy D007918 8 associated lipids
Laryngitis D007827 5 associated lipids
Cardiac Tamponade D002305 7 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Anemia, Hypochromic D000747 5 associated lipids
Dyspnea D004417 10 associated lipids
Listeriosis D008088 12 associated lipids
Periapical Diseases D010483 4 associated lipids
Tremor D014202 15 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Pemphigoid, Bullous D010391 8 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Hypothermia D007035 19 associated lipids
Orthomyxoviridae Infections D009976 3 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Hypoventilation D007040 2 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Paresthesia D010292 7 associated lipids
Pulmonary Emphysema D011656 3 associated lipids
Pleural Effusion D010996 3 associated lipids
Lipidoses D008064 7 associated lipids
Bronchopneumonia D001996 7 associated lipids
Pyoderma D011711 5 associated lipids
Lymphadenitis D008199 8 associated lipids
Drug Eruptions D003875 30 associated lipids
Folliculitis D005499 7 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Synovitis D013585 15 associated lipids
Cleft Palate D002972 9 associated lipids
Herpes Zoster Ophthalmicus D006563 2 associated lipids
Choline Deficiency D002796 16 associated lipids
Anemia, Hemolytic, Autoimmune D000744 5 associated lipids
Gangrene D005734 3 associated lipids
Toxoplasmosis, Animal D014124 5 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Campylobacter Infections D002169 13 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Bacteremia D016470 9 associated lipids
Arthralgia D018771 8 associated lipids
Nausea D009325 7 associated lipids
Prostatitis D011472 5 associated lipids
Factor X Deficiency D005171 2 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Stomatitis D013280 14 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Zhou D and Apicella MA Plasmids with erythromycin resistance and catechol 2,3-dioxygenase- or beta-galactosidase-encoding gene cassettes for use in Neisseria spp. 1996 Gene pmid:8675023
Surrenti E et al. Antral axial forces postprandially and after erythromycin in organic and functional dysmotilities. 1996 Dig. Dis. Sci. pmid:8674390
Nikulin KG [Treatment of acute pneumonia at different stages of the disease]. 1977 Ter. Arkh. pmid:867244
McMeekin TO and Moschella SL Iatrogenic complications of dermatologic therapy. Primum non nocere. 1979 Med. Clin. North Am. pmid:86664
Lode H et al. Treatment of community-acquired pneumonia: a randomized comparison of sparfloxacin, amoxycillin-clavulanic acid and erythromycin. 1995 Eur. Respir. J. pmid:8666093
Johnson AP et al. Prevalence of antibiotic resistance and serotypes in pneumococci in England and Wales: results of observational surveys in 1990 and 1995. 1996 BMJ pmid:8664623
Aleksandrova AE and Vinogradova TI [Immunotropic activity of antimicrobial agents used in tuberculosis]. 1996 Probl Tuberk pmid:8657696
King DE et al. Effectiveness of erythromycin in the treatment of acute bronchitis. 1996 J Fam Pract pmid:8656171
Packman AM et al. Treatment of acne vulgaris: combination of 3% erythromycin and 5% benzoyl peroxide in a gel compared to clindamycin phosphate lotion. 1996 Int. J. Dermatol. pmid:8655242
Kligman AM The treatment of acne. Part III: antibacterials. 1995 Cutis pmid:8654122
Mashkilleyson AL et al. Treatment of syphilis with azithromycin. 1996 Int J STD AIDS pmid:8652720
Pieper R et al. Erythromycin biosynthesis: kinetic studies on a fully active modular polyketide synthase using natural and unnatural substrates. 1996 Biochemistry pmid:8652546
Vickery CL et al. Bacillary angiomatosis presenting as a nasal mass with epistaxis. 1996 Otolaryngol Head Neck Surg pmid:8649879
Dam M et al. Mutations in domain II of 23 S rRNA facilitate translation of a 23 S rRNA-encoded pentapeptide conferring erythromycin resistance. 1996 J. Mol. Biol. pmid:8648637
Yasui N et al. A kinetic and dynamic study of oral alprazolam with and without erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in alprazolam metabolism. 1996 Clin. Pharmacol. Ther. pmid:8646822
Belousov IuB et al. [Dirithromycin in the treatment of infections of the lower respiratory tract]. 1995 Antibiot. Khimioter. pmid:8645058
Tenson T et al. A functional peptide encoded in the Escherichia coli 23S rRNA. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8643630
Gerber MA Antibiotic resistance: relationship to persistence of group A streptococci in the upper respiratory tract. 1996 Pediatrics pmid:8637784
Stopler T et al. [Mycoplasma pneumoniae infections in families in Jerusalem and in kibbutzim]. 1977 Harefuah pmid:863299
Fang CC et al. Erythromycin-induced acute pancreatitis. 1996 J. Toxicol. Clin. Toxicol. pmid:8632521
Cohen LG et al. Erythromycin-induced clozapine toxic reaction. 1996 Arch. Intern. Med. pmid:8629881
Huang XM et al. Base decomposition of erythromycin A methoxime. 1996 J. Antibiot. pmid:8626251
Plaza MA et al. Effect of motilin, somatostatin and bombesin on gastroduodenal myoelectric activity in sheep. 1996 Life Sci. pmid:8622567
Noguchi N et al. Nucleotide sequence and characterization of erythromycin resistance determinant that encodes macrolide 2'-phosphotransferase I in Escherichia coli. 1995 Antimicrob. Agents Chemother. pmid:8619599
Hsueh PR et al. Decreased activity of erythromycin against Streptococcus pyogenes in Taiwan. 1995 Antimicrob. Agents Chemother. pmid:8619575
Miller RD and Fung DY The excretion of enterotoxin B from nongrowing cells of Staphylococcus aureus 4916. 1977 Can. J. Microbiol. pmid:861845
Tzovaras G et al. The effect of intravenous erythromycin on esophageal motility in healthy subjects. 1996 Am. J. Surg. pmid:8615464
Blumenfeld H et al. Trimethoprim and sulfonamide-associated meningoencephalitis with MRI correlates. 1996 Neurology pmid:8614533
Thompson D and Oster G Use of terfenadine and contraindicated drugs. 1996 JAMA pmid:8614120
Harris RZ et al. The effects of menopause and hormone replacement therapies on prednisolone and erythromycin pharmacokinetics. 1996 Clin. Pharmacol. Ther. pmid:8612388
Feierman DE Identification of cytochrome P450 3A1/2 as the major P450 isoform responsible for the metabolism of fentanyl by rat liver microsomes. 1996 Anesth. Analg. pmid:8610902
Kadota J et al. Significance of IL-1beta and IL-1 receptor antagonist (IL-1Ra) in bronchoalveolar lavage fluid (BALF) in patients with diffuse panbronchiolitis (DPB). 1996 Clin. Exp. Immunol. pmid:8608647
Oberg KC and Bauman JL QT interval prolongation and torsades de pointes due to erythromycin lactobionate. 1995 Nov-Dec Pharmacotherapy pmid:8602374
Avila-Campos MJ et al. Distribution of biotypes and antimicrobial susceptibility of Actinobacillus actinomycetemcomitans. 1995 Oral Microbiol. Immunol. pmid:8602348
Burt M et al. Erythromycin stimulates gastric emptying after esophagectomy with gastric replacement: a randomized clinical trial. 1996 J. Thorac. Cardiovasc. Surg. pmid:8601981
Westh H Erythromycin-resistant Staphylococcus aureus in Denmark. 1996 APMIS Suppl. pmid:8600946
The choice of antibacterial drugs. 1996 Med Lett Drugs Ther pmid:8598824
Schachter J and Dawson CR Is trachoma an ocular component of a more generalised chlamydial infection? 1979 Lancet pmid:85939
Vasilos LV et al. [Chemotherapeutic effectiveness of erythromycin, rifampicin and tetracyclines in chlamydiosis and mycoplasmosis in children]. 1995 Antibiot. Khimioter. pmid:8593094
Lucier TS et al. Transition mutations in the 23S rRNA of erythromycin-resistant isolates of Mycoplasma pneumoniae. 1995 Antimicrob. Agents Chemother. pmid:8593017
Bental T et al. Chronic Q fever of pregnancy presenting as Coxiella burnetii placentitis: successful outcome following therapy with erythromycin and rifampin. 1995 Clin. Infect. Dis. pmid:8589167
Lavy E et al. Minimal inhibitory concentrations for canine isolates and oral absorption of roxythromycin in fed and fasted dogs. 1995 J. Vet. Pharmacol. Ther. pmid:8587159
Radulovic S et al. In vitro and in vivo antibiotic susceptibilities of ELB rickettsiae. 1995 Antimicrob. Agents Chemother. pmid:8585746
Hamzehpour MM et al. OprK and OprM define two genetically distinct multidrug efflux systems in Pseudomonas aeruginosa. 1995 Antimicrob. Agents Chemother. pmid:8585714
De Serres G et al. Field effectiveness of erythromycin prophylaxis to prevent pertussis within families. 1995 Pediatr. Infect. Dis. J. pmid:8584364
Bortolussi R et al. Clinical course of pertussis in immunized children. 1995 Pediatr. Infect. Dis. J. pmid:8584314
Tinanoff N et al. Dental treatment of Papillon-Lefèvre syndrome: 15-year follow-up. 1995 J. Clin. Periodontol. pmid:8583017
Minocha A et al. Erythromycin shortens orocaecal transit time in diabetic male subjects: a double-blind placebo-controlled study. 1995 Aliment. Pharmacol. Ther. pmid:8580273
Slomiany BL et al. Sucralfate affects the susceptibility of Helicobacter pylori to antimicrobial agents. 1995 Scand. J. Gastroenterol. Suppl. pmid:8578215
Masclee AA et al. Effect of antrectomy and truncal vagotomy on erythromycin induced pancreatic polypeptide secretion. 1995 Regul. Pept. pmid:8577928