erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Shah F | Erythromycin. | 1998 | Pediatr Rev | pmid:9557068 |
Ross JI et al. | Resistance to erythromycin and clindamycin in cutaneous propionibacteria is associated with mutations in 23S rRNA. | 1998 | Dermatology (Basel) | pmid:9557230 |
Cleary RK et al. | Metronidazole may inhibit intestinal colonization with Clostridium difficile. | 1998 | Dis. Colon Rectum | pmid:9559631 |
Rutman A et al. | Effect of dirithromycin on Haemophilus influenzae infection of the respiratory mucosa. | 1998 | Antimicrob. Agents Chemother. | pmid:9559781 |
Barry AL et al. | Antipneumococcal activities of a ketolide (HMR 3647), a streptogramin (quinupristin-dalfopristin), a macrolide (erythromycin), and a lincosamide (clindamycin). | 1998 | Antimicrob. Agents Chemother. | pmid:9559816 |
Roblin PM and Hammerschlag MR | In vitro activity of a new 8-methoxyquinolone, BAY 12-8039, against Chlamydia pneumoniae. | 1998 | Antimicrob. Agents Chemother. | pmid:9559818 |
Hoppe JE and Bryskier A | In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to two ketolides (HMR 3004 and HMR 3647), four macrolides (azithromycin, clarithromycin, erythromycin A, and roxithromycin), and two ansamycins (rifampin and rifapentine). | 1998 | Antimicrob. Agents Chemother. | pmid:9559823 |
Garcia-Bermejo I et al. | Emergence of erythromycin-resistant, clindamycin-susceptible Streptococcus pyogenes isolates in Madrid, Spain. | 1998 | Antimicrob. Agents Chemother. | pmid:9559831 |
Mitsuyama T et al. | Release of nitric oxide and expression of constitutive nitric oxide synthase of human endothelial cells: enhancement by a 14-membered ring macrolide. | 1998 | Mol. Cell. Biochem. | pmid:9562252 |
Kieran E et al. | Group B streptococcus (GBS) colonisation among expectant Irish mothers. | 1998 Jan-Feb | Ir Med J | pmid:9563251 |
Salah-Bey K et al. | Targeted gene inactivation for the elucidation of deoxysugar biosynthesis in the erythromycin producer Saccharopolyspora erythraea. | 1998 | Mol. Gen. Genet. | pmid:9563840 |
Jamkhedkar PP et al. | Clinico-epidemiologic features of granuloma inguinale in the era of acquired immune deficiency syndrome. | 1998 | Sex Transm Dis | pmid:9564722 |
Delgado LF et al. | Evaluation of the potential cardiotoxicity of the antihistamines terfenadine, astemizole, loratadine, and cetirizine in atopic children. | 1998 | Ann. Allergy Asthma Immunol. | pmid:9564984 |
Riley RJ and Howbrook D | In vitro analysis of the activity of the major human hepatic CYP enzyme (CYP3A4) using [N-methyl-14C]-erythromycin. | 1997 | J Pharmacol Toxicol Methods | pmid:9566442 |
Andrews PA | Interactions with ciprofloxacin and erythromycin leading to aminophylline toxicity. | 1998 | Nephrol. Dial. Transplant. | pmid:9568870 |
Roark GA | Guest clinician: an alternative treatment of RAU (recurrent apthous ulcers). | 1996 | Miss Dent Assoc J | pmid:9571920 |
Juanqin G et al. | Evaluation of the effectiveness of childhood generalized pustular psoriasis treatment in 30 cases. | 1998 Mar-Apr | Pediatr Dermatol | pmid:9572705 |
Elliott RL et al. | Anhydrolide macrolides. 1. Synthesis and antibacterial activity of 2,3-anhydro-6-O-methyl 11,12-carbamate erythromycin A analogues. | 1998 | J. Med. Chem. | pmid:9572890 |
Griesgraber G et al. | Anhydrolide macrolides. 2. Synthesis and antibacterial activity of 2,3-anhydro-6-O-methyl 11,12-carbazate erythromycin A analogues. | 1998 | J. Med. Chem. | pmid:9572891 |
Stephenson GA et al. | Formation of isomorphic desolvates: creating a molecular vacuum. | 1998 | J Pharm Sci | pmid:9572901 |