erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Megacolon D008531 1 associated lipids
Syphilis, Cutaneous D013591 1 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Spider Bites D001098 1 associated lipids
Choroiditis D002833 1 associated lipids
Epidermitis, Exudative, of Swine D004818 1 associated lipids
Heart Murmurs D006337 1 associated lipids
Prolapse D011391 1 associated lipids
Compartment Syndromes D003161 1 associated lipids
Fecal Incontinence D005242 1 associated lipids
Rat-Bite Fever D011906 1 associated lipids
Pelvic Infection D034161 1 associated lipids
Hematemesis D006396 1 associated lipids
Carbuncle D002270 1 associated lipids
Gastric Outlet Obstruction D017219 1 associated lipids
Gas Gangrene D005738 1 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Erysipelas D004886 1 associated lipids
Endocarditis, Subacute Bacterial D004698 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Zmantar T et al. Use of juglone as antibacterial and potential efflux pump inhibitors in Staphylococcus aureus isolated from the oral cavity. 2016 Microb. Pathog. pmid:27816681
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DeLorenzo ME et al. Exposure of the grass shrimp, Palaemonetes pugio, to antimicrobial compounds affects associated Vibrio bacterial density and development of antibiotic resistance. 2016 Environ. Toxicol. pmid:25348372
Xu JY et al. Lysine Malonylome May Affect the Central Metabolism and Erythromycin Biosynthesis Pathway in Saccharopolyspora erythraea. 2016 J. Proteome Res. pmid:27090497
Kang CH and So JS Antibiotic and heavy metal resistance in Shewanella putrefaciens strains isolated from shellfishes collected from West Sea, Korea. 2016 Mar. Pollut. Bull. pmid:27555484
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Choe YJ et al. Emergence of antibiotic-resistant non-vaccine serotype pneumococci in nasopharyngeal carriage in children after the use of extended-valency pneumococcal conjugate vaccines in Korea. 2016 Vaccine pmid:27546875
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Patel MB et al. Hydraphiles enhance antimicrobial potency against Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis. 2016 Bioorg. Med. Chem. pmid:27166575
Mendes RE et al. In Vitro Activity of Lefamulin Tested against Streptococcus pneumoniae with Defined Serotypes, Including Multidrug-Resistant Isolates Causing Lower Respiratory Tract Infections in the United States. 2016 Antimicrob. Agents Chemother. pmid:27161634
Tan C et al. Effects of Low-Dose and Long-Term Treatment with Erythromycin on Interleukin-17 and Interleukin-23 in Peripheral Blood and Induced Sputum in Patients with Stable Chronic Obstructive Pulmonary Disease. 2016 Mediators Inflamm. pmid:27127346
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Mikhail M et al. Orbital cellulitis and multiple abscess formation after strabismus surgery. 2016 Can. J. Ophthalmol. pmid:27085279
Chen Y et al. TEMPO-oxidized Konjac glucomannan as appliance for the preparation of hard capsules. 2016 Carbohydr Polym pmid:27083368
Argyropoulos P et al. Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis. 2016 Biochim. Biophys. Acta pmid:26592346
Jin Y et al. From the Cover: Exposure to Oral Antibiotics Induces Gut Microbiota Dysbiosis Associated with Lipid Metabolism Dysfunction and Low-Grade Inflammation in Mice. 2016 Toxicol. Sci. pmid:27503388
Magnussen MD et al. Antibacterial resistance in Streptococcus pyogenes (GAS) from healthy carriers and tonsillitis patients and association with antibacterial sale in the Faroe Islands. 2016 APMIS pmid:26833774
Seki M et al. A Chronic Respiratory Pasteurella multocida Infection Is Well-Controlled by Long-Term Macrolide Therapy. 2016 Intern. Med. pmid:26831030
Deloose E et al. The motilin receptor agonist erythromycin stimulates hunger and food intake through a cholinergic pathway. 2016 Am. J. Clin. Nutr. pmid:26817505
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Prabhasankar VP et al. Removal rates of antibiotics in four sewage treatment plants in South India. 2016 Environ Sci Pollut Res Int pmid:26797959
Seefeldt AC et al. Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome. 2016 Nucleic Acids Res. pmid:26792896
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Zhou J et al. A seventeen-year observation of the antimicrobial susceptibility of clinical Campylobacter jejuni and the molecular mechanisms of erythromycin-resistant isolates in Beijing, China. 2016 Int. J. Infect. Dis. pmid:26594011
Maye S et al. Transformation of serum-susceptible Escherichia coli O111 with p16Slux plasmid to allow for real-time monitoring of complement-based inactivation of bacterial growth in bovine milk. 2016 J. Dairy Sci. pmid:26585477
Nenquin M and Henquin JC Sulphonylurea receptor-1, sulphonylureas and amplification of insulin secretion by Epac activation in β cells. 2016 Diabetes Obes Metab pmid:26584950
Ohbatake Y et al. Elevated alpha1-acid glycoprotein in gastric cancer patients inhibits the anticancer effects of paclitaxel, effects restored by co-administration of erythromycin. 2016 Clin. Exp. Med. pmid:26359244
Templeton I et al. A physiologically based pharmacokinetic modeling approach to predict drug-drug interactions between domperidone and inhibitors of CYP3A4. 2016 Biopharm Drug Dispos pmid:26356245
Boetsch C et al. Effects of Cytochrome P450 3A4 Inhibitors-Ketoconazole and Erythromycin-on Bitopertin Pharmacokinetics and Comparison with Physiologically Based Modelling Predictions. 2016 Clin Pharmacokinet pmid:26341813
Cluver C et al. Interventions for treating genital Chlamydia trachomatis infection in pregnancy. 2017 Cochrane Database Syst Rev pmid:28937705
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Ishikawa Y et al. Inactivation kinetics and residual activity of CYP3A4 after treatment with erythromycin. 2017 Biopharm Drug Dispos pmid:28425104
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Hawkins PA et al. Cross-resistance to lincosamides, streptogramins A and pleuromutilins in Streptococcus agalactiae isolates from the USA. 2017 J. Antimicrob. Chemother. pmid:28333320
Calle-Miguel L et al. [Resistance rates and phenotypic characterization of Streptococcus pyogenes in a paediatric population in Northern Spain (2005-2015)]. 2017 Rev Esp Quimioter pmid:28233483
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Huang YW et al. Overexpression of SmeDEF Efflux Pump Decreases Aminoglycoside Resistance in Stenotrophomonas maltophilia. 2017 Antimicrob. Agents Chemother. pmid:28193669
Ge LL et al. [Antibiotic resistance analysis of isolates from the hospitalized children in Shanxi Children's Hospital from 2012 to 2014]. 2017 Zhonghua Er Ke Za Zhi pmid:28173648
Liu J et al. Engineering of an Lrp family regulator SACE_Lrp improves erythromycin production in Saccharopolyspora erythraea. 2017 Metab. Eng. pmid:27794466
Olajuyigbe OO et al. In vitro pharmacological interaction of caffeine and first-line antibiotics is antagonistic against clinically important bacterial pathogens. 2017 Acta Biochim. Pol. pmid:28612062
Chang KH et al. Comparison of antibiotic regimens in preterm premature rupture of membranes: neonatal morbidity and 2-year follow-up of neurologic outcome. 2017 J. Matern. Fetal. Neonatal. Med. pmid:27687157
Weber JM et al. Application of In Vitro Transposon Mutagenesis to Erythromycin Strain Improvement in Saccharopolyspora erythraea. 2017 Methods Mol. Biol. pmid:27709581
Na HK et al. Erythromycin infusion prior to endoscopy for acute nonvariceal upper gastrointestinal bleeding: a pilot randomized controlled trial. 2017 Korean J. Intern. Med. pmid:28352063
Li LH et al. [Effect of low dose erythromycin on the proliferation of granulation tissue after tracheal injury]. 2017 Zhonghua Yi Xue Za Zhi pmid:28316160
Fohner AE et al. PharmGKB summary: Macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics. 2017 Pharmacogenet. Genomics pmid:28146011
Michael-Kordatou I et al. On the capacity of ozonation to remove antimicrobial compounds, resistant bacteria and toxicity from urban wastewater effluents. 2017 J. Hazard. Mater. pmid:26947803