erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Manners BT et al. | An investigation of antibiotic resistance of Staphylococcus aureus in general practice. | 1976 | Practitioner | pmid:1046672 |
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De Azavedo JC et al. | Prevalence and mechanisms of macrolide resistance in clinical isolates of group A streptococci from Ontario, Canada. | 1999 | Antimicrob. Agents Chemother. | pmid:10471555 |
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Howard KB et al. | Azithromycin versus erythromycin for community-acquired pneumonia: a cost-minimization analysis. | 1999 | Am J Health Syst Pharm | pmid:10478989 |
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Gómez-Lus R et al. | Is there an ecological relationship between rates of antibiotic resistance of species of the genus Streptococcus? The Spanish Surveillance Group for Respiratory Pathogens. | 1999 | J. Clin. Microbiol. | pmid:10488213 |
Wieckiewicz JA | Relationship between resistance to metallic ions and production of beta-lactamase in strains of Staphylococcus epidermidis. | 1976 | J Hyg Epidemiol Microbiol Immunol | pmid:1048968 |
Kirsten D and Meister W | [Present possibilities of antibiotic therapy in chronic non-specific respiratory diseases (author's transl)]. | 1976 | Z Erkr Atmungsorgane | pmid:1049185 |
Moore PA | Dental therapeutic indications for the newer long-acting macrolide antibiotics. | 1999 | J Am Dent Assoc | pmid:10492541 |
Cash P et al. | A proteomic analysis of erythromycin resistance in Streptococcus pneumoniae. | 1999 | Electrophoresis | pmid:10493130 |
Gibson EM et al. | Transfer of plasmid-mediated antibiotic resistance from streptococci to lactobacilli. | 1979 | J. Bacteriol. | pmid:104973 |
Azuma A and Kudoh S | [Diffuse panbronchiolitis: DPB]. | 1999 | Nippon Rinsho | pmid:10497417 |
Zgoulli S et al. | Microencapsulation of erythromycin and clarithromycin using a spray-drying technique. | 1999 Sep-Oct | J Microencapsul | pmid:10499837 |
Moreno M et al. | Clinical management of tacrolimus drug interactions in renal transplant patients. | 1999 | Transplant. Proc. | pmid:10500564 |
Widdowson CA and Klugman KP | Molecular mechanisms of resistance to commonly used non-betalactam drugs in Streptococcus pneumoniae. | 1999 | Semin Respir Infect | pmid:10501313 |
Rosendal K et al. | Staphylococcus aureus strains isolated in Danish hospitals from January 1st, 1966, to December 31st, 1974. | 1976 | Acta Pathol Microbiol Scand B | pmid:1050144 |
Miossec-Bartoli C et al. | The new ketolide HMR3647 accumulates in the azurophil granules of human polymorphonuclear cells. | 1999 | Antimicrob. Agents Chemother. | pmid:10508024 |
Oster P et al. | Patterns of macrolide resistance determinants among community-acquired Streptococcus pneumoniae isolates over a 5-year period of decreased macrolide susceptibility rates. | 1999 | Antimicrob. Agents Chemother. | pmid:10508033 |
Khan SA et al. | Simultaneous detection of erythromycin-resistant methylase genes ermA and ermC from Staphylococcus spp. by multiplex-PCR. | 1999 | Mol. Cell. Probes | pmid:10508560 |
Ahmad M et al. | Disposition kinetics of erythromycin in normal and experimentally-induced febrile rabbits. | 1999 Apr-Jun | Eur J Drug Metab Pharmacokinet | pmid:10510739 |
McMullin ST et al. | Impact of a Web-based clinical information system on cisapride drug interactions and patient safety. | 1999 | Arch. Intern. Med. | pmid:10510994 |
Kinirons MT et al. | Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A. | 1999 | Clin. Pharmacol. Ther. | pmid:10511057 |
Ball SE et al. | Population distribution and effects on drug metabolism of a genetic variant in the 5' promoter region of CYP3A4. | 1999 | Clin. Pharmacol. Ther. | pmid:10511065 |
Chantarotorn S et al. | Diffuse panbronchiolitis, the first case reports in Thailand. | 1999 | J Med Assoc Thai | pmid:10511794 |
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De Winter BY et al. | Effect of different prokinetic agents and a novel enterokinetic agent on postoperative ileus in rats. | 1999 | Gut | pmid:10517907 |
Xue Q et al. | A multiplasmid approach to preparing large libraries of polyketides. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10518520 |
Sheu BS et al. | A three-day course of intravenous omeprazole plus antibiotics for H. pylori-positive bleeding duodenal ulcer. | 1999 Jul-Aug | Hepatogastroenterology | pmid:10521999 |
Cocito C and Di Giambattista M | The in vitro binding of virginiamycin M to bacteria ribosomes and ribosomal subunits. | 1978 | Mol. Gen. Genet. | pmid:105240 |
Shortridge VD et al. | Prevalence of macrolide resistance mechanisms in Streptococcus pneumoniae isolates from a multicenter antibiotic resistance surveillance study conducted in the United States in 1994-1995. | 1999 | Clin. Infect. Dis. | pmid:10524961 |
Yoh M et al. | Effect of subinhibitory concentrations of antimicrobial agents (quinolones and macrolide) on the production of verotoxin by enterohemorrhagic Escherichia coli O157:H7. | 1999 | Can. J. Microbiol. | pmid:10526400 |
Sato A et al. | Effects of organic anions and vinblastine on biliary excretion of erythromycin in rats. | 1999 | Pharmacology | pmid:10529657 |