erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Hye-Knudsen P | [Lincomycin]. | 1969 | Ugeskr. Laeg. | pmid:5793630 |
HAIGHT TH et al. | Efficacy of erythromycin in the treatment of acute respiratory infections. | 1954 | U S Armed Forces Med J | pmid:13196235 |
LYONS RE et al. | Treatment of bacterial infections of the skin with erythromycin-neomycin ointment. | 1954 | U S Armed Forces Med J | pmid:13196237 |
CHANCEY RL and MEIKLEJOHN GA | Treatment of influenza with erythromycin. | 1954 | U S Armed Forces Med J | pmid:13169449 |
Armangil D et al. | Maternal pertussis is hazardous for a newborn: a case report. | 2010 Mar-Apr | Turk. J. Pediatr. | pmid:20560262 |
Hu P et al. | Erythromycin triggers intussusception in a pediatric patient with Henoch-Schönlein purpura. | 2016 | Turk J Gastroenterol | pmid:27782898 |
Dalgiç B et al. | Chronic intestinal pseudoobstruction: report of four pediatric patients. | 2005 | Turk J Gastroenterol | pmid:16252200 |
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Ben Salah D et al. | [Enterococcus faecalis: a multicenter study on antibiotic resistance]. | 2003 | Tunis Med | pmid:12708176 |
Mahjoubi-Rhimi F et al. | [Antibiotic sensitivity of Streptococcus pneumoniae in Tunisia: results of a multicenter study (1998-1999)]. | 2003 | Tunis Med | pmid:12793066 |
BLOEDNER CD | [Treatment of penicillin resistant staphylococcal infections with erythromycin after a prolonged antibiotic treatment in pulmonary resection]. | 1955 | Tuberkulosearzt | pmid:13291497 |
Goldman KP | Treatment of local complications of BCG vaccination. | 1985 | Tubercle | pmid:4049527 |
Schonell ME et al. | Disseminated infection with Mycobacterium avium: I. Clinical features, treatment and pathology. | 1968 | Tubercle | pmid:4969143 |
Clark J et al. | Disseminated infection with Mycobacterium avium: II. Bacteriology and drug susceptibility. | 1968 | Tubercle | pmid:4969144 |
Keay AJ | "Atypical" mycobacterial lymphadenitis. | 1969 | Tubercle | pmid:5402547 |
MOYES EN and KALINOWSKI SZ | Prophylactic chemotherapy in chronic bronchitis. | 1959 | Tubercle | pmid:13647663 |
Ollar RA et al. | A modified broth dilution assay for antibiotic sensitivity testing of Mycobacterium avium-intracellulare using paraffin slide cultures. | 1991 | Tubercle | pmid:1663284 |
Hanson PJ et al. | Mycobacterium chelonei and abscess formation in soft tissues. | 1987 | Tubercle | pmid:3455569 |
Garcia-Rodriguez JA and Martin-Luengo F | Activity of amikacin, erythromycin and doxycyline against Mycobacterium chelonei and Mycobacterium fortuitum. | 1978 | Tubercle | pmid:726085 |
Lubell Y et al. | Susceptibility of bacterial isolates from community-acquired infections in sub-Saharan Africa and Asia to macrolide antibiotics. | 2011 | Trop. Med. Int. Health | pmid:21740488 |
Chugh TD et al. | In vitro activity of antibacterial agents on Haemophilus influenzae isolates. | 1986 | Trop Geogr Med | pmid:3492795 |
Joshi RM and Lawande RV | Sensitivity pattern and beta-lactamase screening of Neisseria gonorrhoeae strains isolated in Zaria, Northern Nigeria. | 1985 | Trop Geogr Med | pmid:3925605 |
Narasimhan R et al. | Effect of erythromycin and cisapride on emptying of the vagally denervated intrathoracic stomach. | 2002 Jul-Sep | Trop Gastroenterol | pmid:12693153 |
Matinzadeh ZK et al. | Efficacy of topical ophthalmic prophylaxis in prevention of ophthalmia neonatorum. | 2007 | Trop Doct | pmid:17326893 |
Goni BW et al. | Diphtheria in a 7-year-old child in north-eastern Nigeria - management in a resource-poor setting. | 2014 | Trop Doct | pmid:24249028 |
Bell DR | Treatment of venereal diseases. | 1973 | Trop Doct | pmid:4800301 |
van Holten J et al. | Neonatal Borrelia duttoni infection: a report of three cases. | 1997 | Trop Doct | pmid:9133806 |
Mansouri-najand L et al. | Prevalence of multidrug resistance Campylobacter jejuni and Campylobacter coli in chickens slaughtered in selected markets, Malaysia. | 2012 | Trop Biomed | pmid:22735845 |
Igbinosa IH | Prevalence and detection of antibiotic-resistant determinant in Salmonella isolated from food-producing animals. | 2015 | Trop Anim Health Prod | pmid:25348646 |
Bansal BK et al. | Elimination of erythromycin in milk after intramammary administration in cows with specific mastitis: relation to dose, milking frequency and udder health. | 2011 | Trop Anim Health Prod | pmid:20844949 |
Cardozzo EL et al. | [Treatment of dental infections in pediatrics with erythromycin]. | 1978 Apr-Jun | Trib Odontol (B Aires) | pmid:156441 |
Haydée Marchesi M | [Erythromycin stearate in the treatment of common dental infections]. | 1969 Apr-Jun | Trib Odontol (B Aires) | pmid:5258682 |
McOrist S | Obligate intracellular bacteria and antibiotic resistance. | 2000 | Trends Microbiol. | pmid:11121750 |
Kerr JR and Moore JE | Potential for erythromycin resistance in porcine Campylobacter species. | 1995 | Trends Microbiol. | pmid:8574518 |
Lal R et al. | Regulation and manipulation of the gene clusters encoding type-I PKSs. | 2000 | Trends Biotechnol. | pmid:10802562 |
Infection fighters. Key facts about LGV. | 2005 Apr-May | TreatmentUpdate | pmid:17219650 | |
Schmidt LE et al. | Relationship between postoperative erythromycin breath test and early morbidity in liver transplant recipients. | 2003 | Transplantation | pmid:12883193 |
Murray BM et al. | Clinically important interaction of cyclosporine and erythromycin. | 1987 | Transplantation | pmid:3576677 |
Jensen CW et al. | Exacerbation of cyclosporine toxicity by concomitant administration of erythromycin. | 1987 | Transplantation | pmid:3544386 |
Turgeon DK et al. | Prediction of interpatient and intrapatient variation in OG 37-325 dosing requirements by the erythromycin breath test. A prospective study in renal transplant recipients. | 1994 | Transplantation | pmid:8016878 |
Vereerstraeten P et al. | Erythromycin prophylaxis for Legionnaire's disease in immunosuppressed patients in a contaminated hospital environment. | 1986 | Transplantation | pmid:3942015 |
Singh N et al. | Legionella infection in liver transplant recipients: implications for management. | 1993 | Transplantation | pmid:8279037 |
Wilczek H et al. | Nosocomial Legionnaires' disease following renal transplantation. | 1987 | Transplantation | pmid:3296350 |
Morales JM et al. | Severe reversible cyclosporine-induced acute renal failure. A role for urinary PGE2 deficiency? | 1988 | Transplantation | pmid:3293280 |
Nakazawa Y et al. | Relationship between in vivo FK506 clearance and in vitro 13-demethylation activity in living-related liver transplantation. | 1998 | Transplantation | pmid:9808496 |
Cline MS et al. | Bacillary angiomatosis in a renal transplant recipient. | 1999 | Transplantation | pmid:10075597 |
Lauzurica R et al. | Tacrolimus-associated severe bilateral corneal ulcer after renal transplantation. | 2002 | Transplantation | pmid:11923710 |
Gonwa TA et al. | Erythromycin and cyclosporine. | 1986 | Transplantation | pmid:3520996 |