erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Karlsson M et al. | Genetic basis of macrolide and lincosamide resistance in Brachyspira (Serpulina) hyodysenteriae. | 1999 | FEMS Microbiol. Lett. | pmid:10188254 |
Kinirons MT et al. | Effects of ketoconazole on the erythromycin breath test and the dapsone recovery ratio. | 1999 | Br J Clin Pharmacol | pmid:10190659 |
Mthwalo M et al. | Antibiotic resistance of nasopharyngeal isolates of Streptococcus pneumoniae from children in Lesotho. | 1998 | Bull. World Health Organ. | pmid:10191560 |
Isohanni MH et al. | Effect of erythromycin and itraconazole on the pharmacokinetics of oral lignocaine. | 1999 | Pharmacol. Toxicol. | pmid:10193676 |
Stenson BJ et al. | Influence of erythromycin on establishment of feeding in preterm infants: observations from a randomised controlled trial. | 1998 | Arch. Dis. Child. Fetal Neonatal Ed. | pmid:10194995 |
Dorner S and Barta A | Probing ribosome structure by europium-induced RNA cleavage. | 1999 | Biol. Chem. | pmid:10195431 |
Montenez JP et al. | Interactions of macrolide antibiotics (Erythromycin A, roxithromycin, erythromycylamine [Dirithromycin], and azithromycin) with phospholipids: computer-aided conformational analysis and studies on acellular and cell culture models. | 1999 | Toxicol. Appl. Pharmacol. | pmid:10198278 |
Sakaeva DD and Lazareva DN | [The effect of erythromycin on immunity in immunodeficiency]. | 1999 Jan-Feb | Eksp Klin Farmakol | pmid:10198768 |
Jarrett F et al. | Antibiotic bowel preparation and burn wound colonization. | 1976 | Surg Forum | pmid:1019996 |
Scarpignato C and Pelosini I | Management of irritable bowel syndrome: novel approaches to the pharmacology of gut motility. | 1999 | Can. J. Gastroenterol. | pmid:10202210 |
Hall JA and Washabau RJ | Diagnosis and treatment of gastric motility disorders. | 1999 | Vet. Clin. North Am. Small Anim. Pract. | pmid:10202795 |
Vasil'ev TV et al. | [Immediate results of treatment of syphilis with erythromycin simultaneously with bismuth preparations]. | 1976 | Vestn Dermatol Venerol | pmid:1020453 |
MiliavskiÄ AI and Kostenko AM | [Early prevention of syphilis (experimental study)]. | 1976 | Vestn Dermatol Venerol | pmid:1020461 |
Sefton AM | Macrolides and changes in the oral flora. | 1999 | Int. J. Antimicrob. Agents | pmid:10204636 |
Vermeulen B et al. | The formulation and stability of erythromycin-benzoyl peroxide in a topical gel. | 1999 | Int J Pharm | pmid:10205634 |
Vyhnálek J | [Distribution of erythromycin following intramuscular administration in laboratory animals]. | 1978 | Vet Med (Praha) | pmid:102070 |
Mishra A et al. | The effects of erythromycin on the electrocardiogram. | 1999 | Chest | pmid:10208196 |
Imshenetskaia VF | [Erythromycin penetration into the cerebrospinal fluid of patients]. | 1976 | Antibiotiki | pmid:1020930 |
Burstin PP and Marshall CL | Infectious mononucleosis and bilateral peritonsillar abscesses resulting in airway obstruction. | 1998 | J Laryngol Otol | pmid:10209619 |
Tarsi R and Vitali C | [Erythromycin: serum and urine levels following rectal administration (author's transl)]. | 1976 Jul-Aug | Ann Sclavo | pmid:1020971 |