erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Skin Neoplasms D012878 12 associated lipids
Pleurisy D010998 20 associated lipids
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Agrawal V et al. Substrate-specific modulation of CYP3A4 activity by genetic variants of cytochrome P450 oxidoreductase. 2010 Pharmacogenet. Genomics pmid:20697309
Sai Y et al. Proton-coupled erythromycin antiport at rat blood-placenta barrier. 2010 Drug Metab. Dispos. pmid:20566696
Severin JA et al. Nasal carriage of methicillin-resistant and methicillin-sensitive strains of Staphylococcus sciuri in the Indonesian population. 2010 Antimicrob. Agents Chemother. pmid:20837756
Dorobăţ OM et al. [Antibiotic resistance of Gram-positive cocci isolated in 2008]. 2010 Apr-Jun Bacteriol Virusol Parazitol Epidemiol pmid:21553473
Pană M et al. [Study of Streptococcus pneumoniae strains resistant to antibiotics analyzed at "Cantacuzino" NIRDMI during 2006-2008]. 2010 Apr-Jun Bacteriol Virusol Parazitol Epidemiol pmid:21553474
Nica M et al. [Bacterial strains isolated from systemic infections and reported for evaluation and antibiotic resistance surveillance by the "Dr. Victor BabeÅŸ" Clinical Hospital for Infectious and Tropical Diseases, Bucharest]. 2010 Apr-Jun Bacteriol Virusol Parazitol Epidemiol pmid:21553481
Darling EK and McDonald H A meta-analysis of the efficacy of ocular prophylactic agents used for the prevention of gonococcal and chlamydial ophthalmia neonatorum. 2010 Jul-Aug J Midwifery Womens Health pmid:20630358
Smith G Differential diagnosis of red eye. 2010 Jul-Aug Pediatr Nurs pmid:20860262
Tempera G et al. In vitro activity of cefditoren versus other antibiotics against S. pneumoniae clinical strains isolated in Italy. 2010 Jul-Sep Int J Immunopathol Pharmacol pmid:20943054
Pal N et al. Detection of inducible clindamycin resistance among Staphylococcal isolates from different clinical specimens in western India. 2010 Jul-Sep J Postgrad Med pmid:20739762
Poulard F et al. Impact of not measuring residual gastric volume in mechanically ventilated patients receiving early enteral feeding: a prospective before-after study. 2010 Mar-Apr JPEN J Parenter Enteral Nutr pmid:19861528
Torrelo A et al. Extensive comedonal and cystic acne in Patau syndrome. 2010 Mar-Apr Pediatr Dermatol pmid:20537076
Armangil D et al. Maternal pertussis is hazardous for a newborn: a case report. 2010 Mar-Apr Turk. J. Pediatr. pmid:20560262
Bornstein E et al. Photodamage to multidrug-resistant gram-positive and gram-negative bacteria by 870 nm/930 nm light potentiates erythromycin, tetracycline and ciprofloxacin. 2010 May-Jun Photochem. Photobiol. pmid:20408973
Taylor SJ et al. Treating delayed gastric emptying in critical illness: metoclopramide, erythromycin, and bedside (cortrak) nasointestinal tube placement. 2010 May-Jun JPEN J Parenter Enteral Nutr pmid:20467010
Zhang LX et al. Febrile ulceronecrotic Mucha-Habermann's disease with pulmonary involvement. 2010 May-Jun Pediatr Dermatol pmid:20609148
Vorster M et al. Erythromycin as an alternative to reduce interfering extra-cardiac activity in myocardial perfusion imaging. 2010 May-Jun Cardiovasc J Afr pmid:20532452
Dutil M Benzoyl peroxide: enhancing antibiotic efficacy in acne management. 2010 Nov-Dec Skin Therapy Lett. pmid:21076800
Levin TT et al. Case report: delirium due to a diltiazem-fentanyl CYP3A4 drug interaction. 2010 Nov-Dec Gen Hosp Psychiatry pmid:21112467
Taneja N et al. Emergence of tetracycline resistance in Vibrio cholerae O1 biotype El Tor serotype Ogawa from north India. 2010 Oct-Dec Indian J Pathol Microbiol pmid:21045454
Park HH et al. The effect of macrolides on myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts. 2010 Sep-Oct Am J Rhinol Allergy pmid:21244734
Luiz DB et al. Identification of degradation products of erythromycin A arising from ozone and advanced oxidation process treatment. 2010 Sep-Oct Water Environ. Res. pmid:20942335
Al-Talib HI et al. Methicillin-resistant Staphylococcus aureus nosocomial infection trends in Hospital Universiti Sains Malaysia during 2002-2007. 2010 Sep-Oct Ann Saudi Med pmid:20697171
Murray MA et al. Ocular bacillary angiomatosis in an immunocompromised man. 2010 Sep-Oct Ophthal Plast Reconstr Surg pmid:20683276
Zhang W et al. Construction and expression of food-grade β-galactosidase gene in Lactococcus Lactis. 2011 Curr. Microbiol. pmid:20924584
Hewer RC et al. PKA and Epac synergistically inhibit smooth muscle cell proliferation. 2011 J. Mol. Cell. Cardiol. pmid:20971121
Crivellaro S et al. Surveillance of methicillin-resistant Staphylococcus aureus isolated in Torino (northwest Italy). 2011 Diagn. Microbiol. Infect. Dis. pmid:21353947
Kafali H et al. Recurrence of ovarian cyst after sclerotherapy. 2011 Minerva Ginecol pmid:21311417
Shang Y et al. Dexamethasone protects airway epithelial cell line NCI-H292 against lipopolysaccharide induced endoplasmic reticulum stress and apoptosis. 2011 Chin. Med. J. pmid:21362305
Pateron D et al. Erythromycin infusion or gastric lavage for upper gastrointestinal bleeding: a multicenter randomized controlled trial. 2011 Ann Emerg Med pmid:21333385
Cai XJ et al. [Protective effects of erythromycin on human bronchial epithelial cells impaired by interleukin-4]. 2011 Zhonghua Yi Xue Za Zhi pmid:22094097
Otsu K et al. Effects of a novel nonantibiotic macrolide, EM900, on cytokine and mucin gene expression in a human airway epithelial cell line. 2011 Pharmacology pmid:22116077
Nakashima R et al. Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket. 2011 Nature pmid:22121023
Song W et al. Cyclodextrin-erythromycin complexes as a drug delivery device for orthopedic application. 2011 Int J Nanomedicine pmid:22228990
Hiller NL et al. Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. 2011 PLoS ONE pmid:22205975
Wright AJ et al. The risk of hypotension following co-prescription of macrolide antibiotics and calcium-channel blockers. 2011 CMAJ pmid:21242274
Zhang L et al. Synthesis and antibacterial activity of new 4″-O-carbamates of 11,12-cyclic carbonate erythromycin A 6,9-imino ether. 2011 J. Antibiot. pmid:21245870
Nielsen EI et al. Predicting in vitro antibacterial efficacy across experimental designs with a semimechanistic pharmacokinetic-pharmacodynamic model. 2011 Antimicrob. Agents Chemother. pmid:21282424
Belousoff MJ et al. Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21282615
Spigaglia P et al. Surface layer protein A variant of Clostridium difficile PCR-ribotype 027. 2011 Emerging Infect. Dis. pmid:21291621
Huppertz A et al. Evaluation of possible drug-drug interaction between gadoxetic acid and erythromycin as an inhibitor of organic anion transporting peptides (OATP). 2011 J Magn Reson Imaging pmid:21274983
Saderi H et al. Phenotypic and genotypic study of macrolide, lincosamide and streptogramin B (MLSB) resistance in clinical isolates of Staphylococcus aureus in Tehran, Iran. 2011 Med. Sci. Monit. pmid:21278685
Zhang Q et al. Knocking out of tailoring genes eryK and eryG in an industrial erythromycin-producing strain of Saccharopolyspora erythraea leading to overproduction of erythromycin B, C and D at different conversion ratios. 2011 Lett. Appl. Microbiol. pmid:21175699
Lam HS and Ng PC Use of prokinetics in the preterm infant. 2011 Curr. Opin. Pediatr. pmid:21178622
Gardner L et al. Photochemical control of bacterial signal processing using a light-activated erythromycin. 2011 Mol Biosyst pmid:21785768
DeDea L Erythromycin for GI motility; sunscreens; enoxaparin in obesity. 2011 JAAPA pmid:21850912
Maeda Y et al. Comparison of minimum inhibitory concentration by broth microdilution testing versus standard disc diffusion testing in the detection of penicillin, erythromycin and ciprofloxacin resistance in viridans group streptococci. 2011 J. Med. Microbiol. pmid:21852527
Chen Y et al. Determination of time-dependent inactivation of CYP3A4 in cryopreserved human hepatocytes and assessment of human drug-drug interactions. 2011 Drug Metab. Dispos. pmid:21835977
Ahmetagic A et al. Plasmid encoded antibiotics inhibit protozoan predation of Escherichia coli K12. 2011 Plasmid pmid:21839110
Zhou L et al. Serotype distribution and antibiotic resistance of 140 pneumococcal isolates from pediatric patients with upper respiratory infections in Beijing, 2010. 2011 Vaccine pmid:21839135
Wu J et al. Toward improvement of erythromycin A production in an industrial Saccharopolyspora erythraea strain via facilitation of genetic manipulation with an artificial attB site for specific recombination. 2011 Appl. Environ. Microbiol. pmid:21841022
Wunder DB et al. Sorption of antibiotics to biofilm. 2011 Water Res. pmid:21334040
Senthilkumaran S and Subramanian PT Prolonged sedation related to erythromycin and midazolam interaction: a word of caution. 2011 Indian Pediatr pmid:22711153
Ergin A et al. Erythromycin and penicillin resistance mechanisms among viridans group streptococci isolated from blood cultures of adult patients with underlying diseases. 2011 New Microbiol. pmid:21617831
Garber NC et al. Regulation of lectin production by the human pathogens Pseudomonas aeruginosa and Chromobacterium violaceum: effects of choline, trehalose, and ethanol. 2011 Adv. Exp. Med. Biol. pmid:21618111
Sugiyama E et al. The use of 13C-erythromycin as an in vivo probe to evaluate CYP3A-mediated drug interactions in rats. 2011 J Pharm Sci pmid:21618542
Qin X et al. Two paediatric cases of skin and soft-tissue infections due to clindamycin-resistant Staphylococcus aureus carrying a plasmid-encoded vga(A) allelic variant for a putative efflux pump. 2011 Int. J. Antimicrob. Agents pmid:21549571
Sigaroudinia MO and Quayle AR Oral erythromycin relieves dysphagia in a patient with known oesophageal hypomotility disorder who has had a Nissen's fundoplication. 2011 Surgeon pmid:21550524
Szary NM et al. Erythromycin prior to endoscopy in acute upper gastrointestinal bleeding: a meta-analysis. 2011 Scand. J. Gastroenterol. pmid:21561232
Wei Z and Wang J Detection of antibiotic residues in bovine milk by a voltammetric electronic tongue system. 2011 Anal. Chim. Acta pmid:21565301
Ren W and Markel DC Emerging ideas: can erythromycin reduce the risk of aseptic loosening? 2011 Clin. Orthop. Relat. Res. pmid:21584820
Soehnlen MK et al. In vitro antimicrobial inhibition of Mycoplasma bovis isolates submitted to the Pennsylvania Animal Diagnostic Laboratory using flow cytometry and a broth microdilution method. 2011 J. Vet. Diagn. Invest. pmid:21908288
Andini N and Nash KA Expression of tmRNA in mycobacteria is increased by antimicrobial agents that target the ribosome. 2011 FEMS Microbiol. Lett. pmid:21718348
Li AP and Doshi U Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4. 2011 Drug Metab Lett pmid:21722087
Imperi M et al. Invasive neonatal GBS infections from an area-based surveillance study in Italy. 2011 Clin. Microbiol. Infect. pmid:21722258
Kalmokoff M et al. Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. 2011 J. Appl. Microbiol. pmid:21395944
Juntunen P et al. Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. 2011 Vet. Microbiol. pmid:21397412
Boghigian BA et al. Simultaneous production and partitioning of heterologous polyketide and isoprenoid natural products in an Escherichia coli two-phase bioprocess. 2011 J. Ind. Microbiol. Biotechnol. pmid:21487833
Miyashita N et al. Community-acquired macrolide-resistant Mycoplasma pneumoniae pneumonia in patients more than 18 years of age. 2011 J. Infect. Chemother. pmid:20676912
Spurling GK et al. Antibiotics for bronchiolitis in children. 2011 Cochrane Database Syst Rev pmid:21678346
Matsson EM et al. Biliary excretion of ximelagatran and its metabolites and the influence of erythromycin following intraintestinal administration to healthy volunteers. 2011 J Clin Pharmacol pmid:20663994
Miller E et al. Herd immunity and serotype replacement 4 years after seven-valent pneumococcal conjugate vaccination in England and Wales: an observational cohort study. 2011 Lancet Infect Dis pmid:21621466
Song W et al. A novel strontium-doped calcium polyphosphate/erythromycin/poly(vinyl alcohol) composite for bone tissue engineering. 2011 J Biomed Mater Res A pmid:21626667
Wingard JB et al. A novel cell-associated protection assay demonstrates the ability of certain antibiotics to protect ocular surface cell lines from subsequent clinical Staphylococcus aureus challenge. 2011 Antimicrob. Agents Chemother. pmid:21628536
Amachawadi RG et al. Selection of fecal enterococci exhibiting tcrB-mediated copper resistance in pigs fed diets supplemented with copper. 2011 Appl. Environ. Microbiol. pmid:21705534
Tanamachi C et al. [A case of Desulfovibrio desulfuricans cultured from blood in Japan]. 2011 Rinsho Byori pmid:21706860
Mikura S et al. Erythromycin prevents the pulmonary inflammation induced by exposure to cigarette smoke. 2011 Transl Res pmid:21708354
Richter SS et al. Activity of ceftaroline and epidemiologic trends in Staphylococcus aureus isolates collected from 43 medical centers in the United States in 2009. 2011 Antimicrob. Agents Chemother. pmid:21709080
Muruganathan G et al. Interaction study of moxifloxacin and lomefloxacin with co-administered drugs. 2011 Pak J Pharm Sci pmid:21715267
Guo L et al. Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes. 2011 Toxicol. Sci. pmid:21693436
Modali SD and Zgurskaya HI The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter. 2011 Mol. Microbiol. pmid:21696464
Jorgensen JH et al. Collaborative evaluation of an erythromycin-clindamycin combination well for detection of inducible clindamycin resistance in beta-hemolytic streptococci by use of the CLSI broth microdilution method. 2011 J. Clin. Microbiol. pmid:21697321
Ma L et al. Green fluorescent protein labeling of Listeria, Salmonella, and Escherichia coli O157:H7 for safety-related studies. 2011 PLoS ONE pmid:21483738
Xiong L et al. Lignans and neolignans from Sinocalamus affinis and their absolute configurations. 2011 J. Nat. Prod. pmid:21469695
Lobanov KV et al. Reconstruction of Purine Metabolism in Bacillus subtilis to Obtain the Strain Producer of AICAR: A New Drug with a Wide Range of Therapeutic Applications. 2011 Acta Naturae pmid:22649686
Aknin LB et al. It's the recipient that counts: spending money on strong social ties leads to greater happiness than spending on weak social ties. 2011 PLoS ONE pmid:21347326
Manneck T et al. Schistosoma mansoni: antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo. 2011 Exp. Parasitol. pmid:20732321
Wang SM et al. Clinical significance of erythromycin-resistant Campylobacter jejuni in children. 2011 J Microbiol Immunol Infect pmid:21531355
Veiga-Crespo P et al. Synergism between outer membrane proteins and antimicrobials. 2011 Antimicrob. Agents Chemother. pmid:21321143
Dinh QT et al. Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. 2011 Talanta pmid:21807177
Boghigian BA et al. Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions. 2011 Biotechnol. Bioeng. pmid:21337322
Pignatello R et al. Amphiphilic erythromycin-lipoamino acid ion pairs: characterization and in vitro microbiological evaluation. 2011 AAPS PharmSciTech pmid:21479751
Keelan JA et al. Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep. 2011 Am. J. Obstet. Gynecol. pmid:21481833
Fan C and He J Proliferation of antibiotic resistance genes in microbial consortia of sequencing batch reactors (SBRs) upon exposure to trace erythromycin or erythromycin-H2O. 2011 Water Res. pmid:21482429
Franke RM et al. Effect of ABCC2 (MRP2) transport function on erythromycin metabolism. 2011 Clin. Pharmacol. Ther. pmid:21451505
Gozalbes R et al. QSAR-based permeability model for drug-like compounds. 2011 Bioorg. Med. Chem. pmid:21458999
Boleda MA et al. Behavior of pharmaceuticals and drugs of abuse in a drinking water treatment plant (DWTP) using combined conventional and ultrafiltration and reverse osmosis (UF/RO) treatments. 2011 Environ. Pollut. pmid:21459501
Meinertz JR et al. Chronic toxicity of erythromycin thiocyanate to Daphnia magna in a flow-through, continuous exposure test system. 2011 Bull Environ Contam Toxicol pmid:21984684
Li Y et al. Molecular characterization of erm(B)- and mef(E)-mediated erythromycin-resistant Streptococcus pneumoniae in China and complete DNA sequence of Tn2010. 2011 J. Appl. Microbiol. pmid:20961364
Vuppalanchi R et al. Drug-induced QT prolongation in cirrhotic patients with transjugular intrahepatic portosystemic shunt. 2011 J. Clin. Gastroenterol. pmid:20962670