erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Meningitis, Listeria D008584 1 associated lipids
Hereditary Sensory and Autonomic Neuropathies D009477 1 associated lipids
Megacolon D008531 1 associated lipids
Choroiditis D002833 1 associated lipids
Syphilis, Cutaneous D013591 1 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Spider Bites D001098 1 associated lipids
Epidermitis, Exudative, of Swine D004818 1 associated lipids
Heart Murmurs D006337 1 associated lipids
Tooth Fractures D014082 2 associated lipids
Pneumonia, Staphylococcal D011023 2 associated lipids
Gardner Syndrome D005736 2 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Rickettsiaceae Infections D012288 2 associated lipids
Rubella D012409 2 associated lipids
Seroma D049291 2 associated lipids
Bile Reflux D001655 2 associated lipids
Wounds, Gunshot D014948 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Pancreatic Fistula D010185 2 associated lipids
Furunculosis D005667 2 associated lipids
Porphyrias D011164 2 associated lipids
Periodontal Abscess D010508 2 associated lipids
Protein-Losing Enteropathies D011504 2 associated lipids
Hypoventilation D007040 2 associated lipids
Bites, Human D001734 2 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Pericoronitis D010497 2 associated lipids
Herpes Zoster Ophthalmicus D006563 2 associated lipids
Abdominal Abscess D018784 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Uterine Cervical Erosion D002579 2 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Common Cold D003139 2 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Tooth Diseases D014076 2 associated lipids
Animal Diseases D000820 2 associated lipids
Auditory Diseases, Central D001304 2 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Angiomatosis, Bacillary D016917 2 associated lipids
Torsades de Pointes D016171 2 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Huang M et al. Single nucleotide polymorphism of CYP3A4 intron 2 and its influence on CYP3A4 mRNA expression and liver enzymatic activity in human liver. 2015 J. Huazhong Univ. Sci. Technol. Med. Sci. pmid:26223917
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Takagi M et al. Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. 2015 Drug Metab. Pharmacokinet. pmid:26195223
Aydin S et al. Development of antibiotic resistance genes in microbial communities during long-term operation of anaerobic reactors in the treatment of pharmaceutical wastewater. 2015 Water Res. pmid:26188597
Fayed B et al. Multiplexed integrating plasmids for engineering of the erythromycin gene cluster for expression in Streptomyces spp. and combinatorial biosynthesis. 2015 Appl. Environ. Microbiol. pmid:26431970
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Gagliotti C et al. A regionwide intervention to promote appropriate antibiotic use in children reversed trends in erythromycin resistance to Streptococcus pyogenes. 2015 Acta Paediatr. pmid:26058421
Dermota U et al. Survey of community-associated-methicillin-Resistant Staphylococcus aureus in Slovenia: identification of community-associated and livestock-associated clones. 2015 Int. J. Med. Microbiol. pmid:26055648
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Reeves M et al. Acute colonic pseudo-obstruction in pregnancy. 2015 ANZ J Surg pmid:26044983
Vlakh EG et al. Preparation and characterization of macroporous monoliths imprinted with erythromycin. 2015 J Sep Sci pmid:26033867
Wang L et al. Changes in diversity of cultured bacteria resistant to erythromycin and tetracycline in swine manure during simulated composting and lagoon storage. 2015 Lett. Appl. Microbiol. pmid:26031793
Wang Z et al. MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation. 2015 PLoS ONE pmid:25706647
Yoon IA et al. Clinical significance of serotype V among infants with invasive group B streptococcal infections in South Korea. 2015 Int. J. Infect. Dis. pmid:26026823
Gherardi G et al. Decline in macrolide resistance rates among Streptococcus pyogenes causing pharyngitis in children isolated in Italy. 2015 Eur. J. Clin. Microbiol. Infect. Dis. pmid:26024763
Reveiz L and Cardona AF Antibiotics for acute laryngitis in adults. 2015 Cochrane Database Syst Rev pmid:26002823
Pesola AK et al. Clindamycin resistant emm33 Streptococcus pyogenes emerged among invasive infections in Helsinki metropolitan area, Finland, 2012 to 2013. 2015 Euro Surveill. pmid:25990232
Sun XJ et al. Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-δ/Akt pathway and increasing GR expression. 2015 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:25957293
Wang P et al. Serotypes, antibiotic susceptibilities, and multi-locus sequence type profiles of Streptococcus agalactiae isolates circulating in Beijing, China. 2015 PLoS ONE pmid:25781346
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Tojima I et al. Anti-inflammatory effects of a novel non-antibiotic macrolide, EM900, on mucus secretion of airway epithelium. 2015 Auris Nasus Larynx pmid:25769240
Hao H et al. Identification of Campylobacter jejuni and determination of point mutations associated with macrolide resistance using a multiplex TaqMan MGB real-time PCR. 2015 J. Appl. Microbiol. pmid:25766481
Nonaka L et al. Novel macrolide-resistance genes, mef(C) and mph(G), carried by plasmids from Vibrio and Photobacterium isolated from sediment and seawater of a coastal aquaculture site. 2015 Lett. Appl. Microbiol. pmid:25765542
Mills RO et al. Epidemiology of pneumococcal carriage in children under five years of age in Accra, Ghana. 2015 Infect Dis (Lond) pmid:25761718
Hersch M et al. Prokinetic drugs for gastric emptying in critically ill ventilated patients: Analysis through breath testing. 2015 J Crit Care pmid:25746849
Lee S et al. Functional analysis of Vibrio vulnificus RND efflux pumps homologous to Vibrio cholerae VexAB and VexCD, and to Escherichia coli AcrAB. 2015 J. Microbiol. pmid:25740377
Lysnyansky I et al. Decreased Susceptibility to Macrolide-Lincosamide in Mycoplasma synoviae Is Associated with Mutations in 23S Ribosomal RNA. 2015 Microb. Drug Resist. pmid:25734368
Abreu AC et al. Combinatorial Activity of Flavonoids with Antibiotics Against Drug-Resistant Staphylococcus aureus. 2015 Microb. Drug Resist. pmid:25734256
Ou H et al. Selective removal of erythromycin by magnetic imprinted polymers synthesized from chitosan-stabilized Pickering emulsion. 2015 J. Hazard. Mater. pmid:25704432
Ikebe T et al. Increased prevalence of group A streptococcus isolates in streptococcal toxic shock syndrome cases in Japan from 2010 to 2012. 2015 Epidemiol. Infect. pmid:25703404
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Chemler JA et al. Evolution of Efficient Modular Polyketide Synthases by Homologous Recombination. 2015 J. Am. Chem. Soc. pmid:26230368
Choi JH et al. Distribution of emm types among group A Streptococcus isolates from children in Korea. 2015 Diagn. Microbiol. Infect. Dis. pmid:25700867
Luo H et al. Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. 2015 Avian Pathol. pmid:25690020
Azadegan A et al. Detection of the efflux-mediated erythromycin resistance transposon in Streptococcus pneumoniae. 2015 Ann Lab Med pmid:25553281
Wu H et al. Capturing the target genes of BldD in Saccharopolyspora erythraea using improved genomic SELEX method. 2015 Appl. Microbiol. Biotechnol. pmid:25549616
Cetecioglu Z et al. Acute effect of erythromycin on metabolic transformations of volatile fatty acid mixture under anaerobic conditions. 2015 Chemosphere pmid:25542637
Novak I and Kovač B Electronic structure of antibiotic erythromycin. 2015 Spectrochim Acta A Mol Biomol Spectrosc pmid:25528514
Ansari NN et al. A randomized clinical trial comparing pulsed ultrasound and erythromycin phonophoresis in the treatment of patients with chronic rhinosinusitis. 2015 Physiother Theory Pract pmid:25495769
Nagelreiter C et al. Dilution of semi-solid creams: influence of various production parameters on rheological properties and skin penetration. 2015 Int J Pharm pmid:25475015
Harmer CJ et al. A type 2 A/C2 plasmid carrying the aacC4 apramycin resistance gene and the erm(42) erythromycin resistance gene recovered from two Salmonella enterica serovars. 2015 J. Antimicrob. Chemother. pmid:25468903
Wan J et al. Effect of erythromycin exposure on the growth, antioxidant system and photosynthesis of Microcystis flos-aquae. 2015 J. Hazard. Mater. pmid:25464321
Zhou Z et al. Macrolide-resistant Mycoplasma pneumoniae in adults in Zhejiang, China. 2015 Antimicrob. Agents Chemother. pmid:25451048
Hur J et al. Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. 2015 Chem. Res. Toxicol. pmid:25811541
Galvidis I et al. Group determination of 14-membered macrolide antibiotics and azithromycin using antibodies against common epitopes. 2015 Anal. Biochem. pmid:25256165
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Kempe H et al. Molecularly imprinted polymer nanocarriers for sustained release of erythromycin. 2015 Pharm. Res. pmid:25103333
Chen Y et al. The glucose RQ-feedback control leading to improved erythromycin production by a recombinant strain Saccharopolyspora erythraea ZL1004 and its scale-up to 372-m(3) fermenter. 2015 Bioprocess Biosyst Eng pmid:25042891
Llorca M et al. Identification of new transformation products during enzymatic treatment of tetracycline and erythromycin antibiotics at laboratory scale by an on-line turbulent flow liquid-chromatography coupled to a high resolution mass spectrometer LTQ-Orbitrap. 2015 Chemosphere pmid:24972175
Yang J et al. Improving heterologous polyketide production in Escherichia coli by transporter engineering. 2015 Appl. Microbiol. Biotechnol. pmid:26062534
Song LY et al. Exploring Synergy between Classic Mutagens and Antibiotics To Examine Mechanisms of Synergy and Antibiotic Action. 2015 Antimicrob. Agents Chemother. pmid:26711761
Pavlova A and Gumbart JC Parametrization of macrolide antibiotics using the force field toolkit. 2015 J Comput Chem pmid:26280362
Aydın S et al. Inhibitory effect of erythromycin, tetracycline and sulfamethoxazole antibiotics on anaerobic treatment of a pharmaceutical wastewater. 2015 Water Sci. Technol. pmid:26038926
Daghighi S et al. Influence of antibiotic pressure on bacterial bioluminescence, with emphasis on Staphylococcus aureus. 2015 Int. J. Antimicrob. Agents pmid:26526893
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Fedashchin A et al. Random transposon mutagenesis of the Saccharopolyspora erythraea genome reveals additional genes influencing erythromycin biosynthesis. 2015 FEMS Microbiol. Lett. pmid:26468041
Lu H et al. High frequency of the 23S rRNA A2058G mutation of Treponema pallidum in Shanghai is associated with a current strategy for the treatment of syphilis. 2015 Emerg Microbes Infect pmid:26038763
Yi X et al. Improved detection of multiple environmental antibiotics through an optimized sample extraction strategy in liquid chromatography-mass spectrometry analysis. 2015 Anal Bioanal Chem pmid:26449847
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Yamaguchi M et al. Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche. 2015 Cell Rep pmid:26440893
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Liao CH et al. DasR is a pleiotropic regulator required for antibiotic production, pigment biosynthesis, and morphological development in Saccharopolyspora erythraea. 2015 Appl. Microbiol. Biotechnol. pmid:26272095
Å mitran A et al. Effects of penicillin and erythromycin on adherence of invasive and noninvasive isolates of Streptococcus pyogenes to laminin. 2015 Mem. Inst. Oswaldo Cruz pmid:26270594
Wang YL et al. Development of a Method for the Analysis of Multiclass Antibiotic Residues in Milk Using QuEChERS and Liquid Chromatography-Tandem Mass Spectrometry. 2015 Foodborne Pathog. Dis. pmid:26258263
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Peyre L et al. High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical's bio-activation with regards hepatotoxicity. 2015 Toxicol In Vitro pmid:26239606
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Mazumdar G and Shome K Stevens-Johnson syndrome following use of metronidazole in a dental patient. 2014 Jan-Feb Indian J Pharmacol pmid:24550598
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Cetecioglu Z Aerobic inhibition assessment for anaerobic treatment effluent of antibiotic production wastewater. 2014 Environ Sci Pollut Res Int pmid:24146324
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Labbeiki G et al. Enhanced oxygen transfer rate and bioprocess yield by using magnetite nanoparticles in fermentation media of erythromycin. 2014 Daru pmid:25223458
Bharucha AE et al. A prospective randomized controlled study of erythromycin on gastric and small intestinal distention: implications for MR enterography. 2014 Eur J Radiol pmid:25217123
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Kara M et al. Expression changes of antioxidant, apoptotic, anti-apoptotic genes and miR-15b-34a-21-98 in over tissue by using erythromycin, quinacrine and tetracycline in non-surgical sterilization. 2014 Mol. Biol. Rep. pmid:25195052
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Moore KT et al. An open-label study to estimate the effect of steady-state erythromycin on the pharmacokinetics, pharmacodynamics, and safety of a single dose of rivaroxaban in subjects with renal impairment and normal renal function. 2014 J Clin Pharmacol pmid:24964176
Montilla A et al. Genetic environment of the lnu(B) gene in a Streptococcus agalactiae clinical isolate. 2014 Antimicrob. Agents Chemother. pmid:24957835
Komiya K et al. Long-term, low-dose erythromycin monotherapy for Mycobacterium avium complex lung disease: a propensity score analysis. 2014 Int. J. Antimicrob. Agents pmid:24948577
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Crumb WJ Allosteric effects of erythromycin pretreatment on thioridazine block of hERG potassium channels. 2014 Br. J. Pharmacol. pmid:24417241
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Aydin S et al. Performance of anaerobic sequencing batch reactor in the treatment of pharmaceutical wastewater containing erythromycin and sulfamethoxazole mixture. 2014 Water Sci. Technol. pmid:25429450