erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Padovan J et al. | Investigating the barriers to bioavailability of macrolide antibiotics in the rat. | 2012 | Eur J Drug Metab Pharmacokinet | pmid:22113743 |
| Wills RH et al. | Structural characterization of polyketides using high mass accuracy tandem mass spectrometry. | 2012 | Anal. Chem. | pmid:22985101 |
| Sugimoto T et al. | Synthesis and structure-activity relationship of a novel class of 15-membered macrolide antibiotics known as '11a-azalides'. | 2012 | Bioorg. Med. Chem. | pmid:22925450 |
| Sugimoto T et al. | Synthesis and antibacterial activity of 6-O-(heteroaryl-isoxazolyl)propynyl 2-fluoro ketolides. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22858102 |
| März A et al. | Fluorescence dye as novel label molecule for quantitative SERS investigations of an antibiotic. | 2012 | Anal Bioanal Chem | pmid:21822777 |
| Gant CM et al. | Serotype distribution and antimicrobial resistance of invasive pneumococcal disease strains in the Comunidad Valenciana, Spain, during the winter of 2009-2010: low PCV7 coverage and high levofloxacin resistance. | 2012 | Antimicrob. Agents Chemother. | pmid:22751535 |
| Kim J et al. | Copper resistance and its relationship to erythromycin resistance in Enterococcus isolates from bovine milk samples in Korea. | 2012 | J. Microbiol. | pmid:22752920 |
| De Sousa A and Kalra G | Drug therapy of attention deficit hyperactivity disorder: current trends. | 2012 | Mens Sana Monogr | pmid:22654382 |
| Ullrich K et al. | Neuroretinitis following bull ant sting. | 2012 | BMJ Case Rep | pmid:22865803 |
| Pollett S et al. | Campylobacter antimicrobial resistance in Peru: a ten-year observational study. | 2012 | BMC Infect. Dis. | pmid:22898609 |
| Licona-Cassani C et al. | Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production. | 2012 | Antonie Van Leeuwenhoek | pmid:22847261 |
| Shimizu S et al. | Reactivity of lignin with different composition of aromatic syringyl/guaiacyl structures and erythro/threo side chain structures in β-O-4 type during alkaline delignification: as a basis for the different degradability of hardwood and softwood lignin. | 2012 | J. Agric. Food Chem. | pmid:22694300 |
| Perry DM et al. | Identification and characterization of protein phosphatase 2C activation by ceramide. | 2012 | J. Lipid Res. | pmid:22615346 |
| Deane AM et al. | Randomized double-blind crossover study to determine the effects of erythromycin on small intestinal nutrient absorption and transit in the critically ill. | 2012 | Am. J. Clin. Nutr. | pmid:22572649 |
| Senhorinho GN et al. | Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis. | 2012 | Anaerobe | pmid:22609780 |
| Bidet P et al. | Identification of group A streptococcal emm types commonly associated with invasive infections and antimicrobial resistance by the use of multiplex PCR and high-resolution melting analysis. | 2012 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:22610663 |
| Rocco L et al. | Micronucleus test and comet assay for the evaluation of zebrafish genomic damage induced by erythromycin and lincomycin. | 2012 | Environ. Toxicol. | pmid:21384490 |
| Liu X et al. | [The effect of biyuanshu oral liquid on the formation of Pseudomonas aeruginosa biofilms in vitro]. | 2012 | Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:23156807 |
| El Hafidi N et al. | [Mycoplasma pneumoniae encephalitis associated with basal ganglia necrosis]. | 2012 | Rev. Neurol. (Paris) | pmid:22244792 |
| Tolosa L et al. | Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. | 2012 | Toxicol. Sci. | pmid:22331495 |
| Henningsen E and Bygum A | Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. | 2011 Sep-Oct | Pediatr Dermatol | pmid:21895758 |
| Ezhova NM et al. | [Molecularly imprinted hydrophilic polymer sorbents for selective sorption of erythromycin]. | 2011 Nov-Dec | Prikl. Biokhim. Mikrobiol. | pmid:22288199 |
| Zhang W et al. | Construction and expression of food-grade β-galactosidase gene in Lactococcus Lactis. | 2011 | Curr. Microbiol. | pmid:20924584 |
| Hewer RC et al. | PKA and Epac synergistically inhibit smooth muscle cell proliferation. | 2011 | J. Mol. Cell. Cardiol. | pmid:20971121 |
| Fessler AT et al. | Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. | 2011 | Antimicrob. Agents Chemother. | pmid:20876371 |
| Otsu K et al. | Effects of a novel nonantibiotic macrolide, EM900, on cytokine and mucin gene expression in a human airway epithelial cell line. | 2011 | Pharmacology | pmid:22116077 |
| Nakashima R et al. | Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket. | 2011 | Nature | pmid:22121023 |
| Abarzúa F et al. | [Streptococcus agalactiae increase in resistance to erythromycin and clindamycin in vaginal-anal colonization in third quarter of pregnancy in one decade of universal screening]. | 2011 | Rev Chilena Infectol | pmid:22052397 |
| Song W et al. | Cyclodextrin-erythromycin complexes as a drug delivery device for orthopedic application. | 2011 | Int J Nanomedicine | pmid:22228990 |
| Hiller NL et al. | Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. | 2011 | PLoS ONE | pmid:22205975 |
| Tachecà I et al. | Electrogastrography in experimental pigs: the influence of gastrointestinal injury induced by dextran sodium sulphate on porcine gastric erythromycin-stimulated myoelectric activity. | 2011 | Neuro Endocrinol. Lett. | pmid:22167215 |
| Spigaglia P et al. | Surface layer protein A variant of Clostridium difficile PCR-ribotype 027. | 2011 | Emerging Infect. Dis. | pmid:21291621 |
| Huppertz A et al. | Evaluation of possible drug-drug interaction between gadoxetic acid and erythromycin as an inhibitor of organic anion transporting peptides (OATP). | 2011 | J Magn Reson Imaging | pmid:21274983 |
| Saderi H et al. | Phenotypic and genotypic study of macrolide, lincosamide and streptogramin B (MLSB) resistance in clinical isolates of Staphylococcus aureus in Tehran, Iran. | 2011 | Med. Sci. Monit. | pmid:21278685 |
| Zhang Q et al. | Knocking out of tailoring genes eryK and eryG in an industrial erythromycin-producing strain of Saccharopolyspora erythraea leading to overproduction of erythromycin B, C and D at different conversion ratios. | 2011 | Lett. Appl. Microbiol. | pmid:21175699 |
| Lam HS and Ng PC | Use of prokinetics in the preterm infant. | 2011 | Curr. Opin. Pediatr. | pmid:21178622 |
| Ma S et al. | Synthesis and antibacterial evaluation of novel clarithromycin derivatives with C-4″ elongated arylalkyl groups against macrolide-resistant strains. | 2011 | Eur J Med Chem | pmid:21159410 |
| Mak PJ et al. | Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. | 2011 | J. Am. Chem. Soc. | pmid:21207936 |
| Ren GW et al. | Rapid detection of point mutations in domain V of the 23S rRNA gene in erythromycin-resistant Campylobacter isolates by pyrosequencing. | 2011 | Foodborne Pathog. Dis. | pmid:21166562 |
| Srinivasan U et al. | Identification of a novel keyhole phenotype in double-disk diffusion assays of clindamycin-resistant erythromycin-sensitive strains of Streptococcus agalactiae. | 2011 | Microb. Drug Resist. | pmid:21166574 |
| Ahmetagic A et al. | Plasmid encoded antibiotics inhibit protozoan predation of Escherichia coli K12. | 2011 | Plasmid | pmid:21839110 |
| Zhou L et al. | Serotype distribution and antibiotic resistance of 140 pneumococcal isolates from pediatric patients with upper respiratory infections in Beijing, 2010. | 2011 | Vaccine | pmid:21839135 |
| Wu J et al. | Toward improvement of erythromycin A production in an industrial Saccharopolyspora erythraea strain via facilitation of genetic manipulation with an artificial attB site for specific recombination. | 2011 | Appl. Environ. Microbiol. | pmid:21841022 |
| Raynes Greenow CH et al. | Antibiotics for ureaplasma in the vagina in pregnancy. | 2011 | Cochrane Database Syst Rev | pmid:21901685 |
| Wunder DB et al. | Sorption of antibiotics to biofilm. | 2011 | Water Res. | pmid:21334040 |
| Senthilkumaran S and Subramanian PT | Prolonged sedation related to erythromycin and midazolam interaction: a word of caution. | 2011 | Indian Pediatr | pmid:22711153 |
| Sonnevend à et al. | Lack of correlation between the 257C-to-T mutation in the gyrA gene and clinical severity of Campylobacter jejuni infection in a region of high incidence of ciprofloxacin resistance. | 2011 | Scand. J. Infect. Dis. | pmid:21905953 |
| Jessick AM et al. | Optimization of analytical methods to improve detection of erythromycin from water and sediment. | 2011 | J Environ Sci Health B | pmid:21877980 |
| Lee CY et al. | Identification and treatment of bisphosphonate-associated actinomycotic osteonecrosis of the jaws. | 2011 | Implant Dent | pmid:21881516 |
| Szary NM et al. | Erythromycin prior to endoscopy in acute upper gastrointestinal bleeding: a meta-analysis. | 2011 | Scand. J. Gastroenterol. | pmid:21561232 |
| Wei Z and Wang J | Detection of antibiotic residues in bovine milk by a voltammetric electronic tongue system. | 2011 | Anal. Chim. Acta | pmid:21565301 |
| Ren W and Markel DC | Emerging ideas: can erythromycin reduce the risk of aseptic loosening? | 2011 | Clin. Orthop. Relat. Res. | pmid:21584820 |
| Torra S et al. | Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial). | 2011 | Int J Obes (Lond) | pmid:20938444 |
| Li MJ et al. | High electrochemiluminescence of a new water-soluble iridium(III) complex for determination of antibiotics. | 2011 | Analyst | pmid:20944848 |
| Andini N and Nash KA | Expression of tmRNA in mycobacteria is increased by antimicrobial agents that target the ribosome. | 2011 | FEMS Microbiol. Lett. | pmid:21718348 |
| Li AP and Doshi U | Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4. | 2011 | Drug Metab Lett | pmid:21722087 |
| Imperi M et al. | Invasive neonatal GBS infections from an area-based surveillance study in Italy. | 2011 | Clin. Microbiol. Infect. | pmid:21722258 |
| Wan G et al. | Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. | 2011 | Cell. Signal. | pmid:21723942 |
| Kalmokoff M et al. | Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. | 2011 | J. Appl. Microbiol. | pmid:21395944 |
| Juntunen P et al. | Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. | 2011 | Vet. Microbiol. | pmid:21397412 |
| Boghigian BA et al. | Simultaneous production and partitioning of heterologous polyketide and isoprenoid natural products in an Escherichia coli two-phase bioprocess. | 2011 | J. Ind. Microbiol. Biotechnol. | pmid:21487833 |
| Miyashita N et al. | Community-acquired macrolide-resistant Mycoplasma pneumoniae pneumonia in patients more than 18 years of age. | 2011 | J. Infect. Chemother. | pmid:20676912 |
| Chen I et al. | Emergence of erythromycin- and clindamycin-resistant Streptococcus pyogenes emm 90 strains in Hawaii. | 2011 | J. Clin. Microbiol. | pmid:21068284 |
| You L et al. | Dynamic multi-component covalent assembly for the reversible binding of secondary alcohols and chirality sensing. | 2011 | Nat Chem | pmid:22109274 |
| Bilk S et al. | Antimicrobial susceptibilities and occurrence of resistance genes in bovine Helcococcus ovis isolates. | 2011 | Vet. Microbiol. | pmid:21131144 |
| Zou X et al. | An assessment of seed quality on erythromycin production by recombinant Saccharopolyspora erythraea strain. | 2011 | Bioresour. Technol. | pmid:21134745 |
| Richter SS et al. | Activity of ceftaroline and epidemiologic trends in Staphylococcus aureus isolates collected from 43 medical centers in the United States in 2009. | 2011 | Antimicrob. Agents Chemother. | pmid:21709080 |
| Muruganathan G et al. | Interaction study of moxifloxacin and lomefloxacin with co-administered drugs. | 2011 | Pak J Pharm Sci | pmid:21715267 |
| Guo L et al. | Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes. | 2011 | Toxicol. Sci. | pmid:21693436 |
| Modali SD and Zgurskaya HI | The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter. | 2011 | Mol. Microbiol. | pmid:21696464 |
| Jorgensen JH et al. | Collaborative evaluation of an erythromycin-clindamycin combination well for detection of inducible clindamycin resistance in beta-hemolytic streptococci by use of the CLSI broth microdilution method. | 2011 | J. Clin. Microbiol. | pmid:21697321 |
| Wenzel F et al. | Alterations of serum erythropoietin and thrombopoietin levels in patients undergoing Coronary Artery Bypass Grafting (CABG). | 2011 | Clin. Hemorheol. Microcirc. | pmid:22214710 |
| Mansi Y et al. | Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants. | 2011 | Neonatology | pmid:21701222 |
| Amarir-Bouhram J et al. | Low efficiency of homology-facilitated illegitimate recombination during conjugation in Escherichia coli. | 2011 | PLoS ONE | pmid:22194937 |
| Ng PC | Erythromycin as a prokinetic agent in newborns--useful or doubtful. Commentary on Y. Mansi et al.: Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants (Neonatology 2011;100:290-294). | 2011 | Neonatology | pmid:21701224 |
| Sarig H et al. | Functional studies of cochleate assemblies of an oligo-acyl-lysyl with lipid mixtures for combating bacterial multidrug resistance. | 2011 | FASEB J. | pmid:21676947 |
| Shingate BB et al. | Stereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain. | 2011 | Eur J Med Chem | pmid:21664730 |
| Hoa PT et al. | Antibiotic contamination and occurrence of antibiotic-resistant bacteria in aquatic environments of northern Vietnam. | 2011 | Sci. Total Environ. | pmid:21669325 |
| Joao EC et al. | Group B Streptococcus in a cohort of HIV-infected pregnant women: prevalence of colonization, identification and antimicrobial susceptibility profile. | 2011 | Scand. J. Infect. Dis. | pmid:21671824 |
| Manneck T et al. | Schistosoma mansoni: antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo. | 2011 | Exp. Parasitol. | pmid:20732321 |
| Boghigian BA et al. | Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions. | 2011 | Biotechnol. Bioeng. | pmid:21337322 |
| Kataoka M et al. | Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation. | 2011 | Eur J Pharm Sci | pmid:21963456 |
| Hernández y Ballinas A et al. | [Comparison of maternal and perinatal outcomes in the conservative treatment preterm premature membrane rupture between the use of erythromycin and clindamycin]. | 2011 | Ginecol Obstet Mex | pmid:21966834 |
| Gupta R et al. | A 14-year-old with rectal bleeding and abdominal pain. | 2011 | J. Pediatr. Gastroenterol. Nutr. | pmid:21970991 |
| Heath AP et al. | An algorithm for efficient identification of branched metabolic pathways. | 2011 | J. Comput. Biol. | pmid:21999288 |
| Fan C and He J | Proliferation of antibiotic resistance genes in microbial consortia of sequencing batch reactors (SBRs) upon exposure to trace erythromycin or erythromycin-H2O. | 2011 | Water Res. | pmid:21482429 |
| Ho PL et al. | Changes in nasopharyngeal carriage and serotype distribution of antibiotic-resistant Streptococcus pneumoniae before and after the introduction of 7-valent pneumococcal conjugate vaccine in Hong Kong. | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:22000087 |
| Franke RM et al. | Effect of ABCC2 (MRP2) transport function on erythromycin metabolism. | 2011 | Clin. Pharmacol. Ther. | pmid:21451505 |
| Gozalbes R et al. | QSAR-based permeability model for drug-like compounds. | 2011 | Bioorg. Med. Chem. | pmid:21458999 |
| Boleda MA et al. | Behavior of pharmaceuticals and drugs of abuse in a drinking water treatment plant (DWTP) using combined conventional and ultrafiltration and reverse osmosis (UF/RO) treatments. | 2011 | Environ. Pollut. | pmid:21459501 |
| Zhang Z et al. | Novel molecularly imprinted polymers based on multi-walled carbon nanotubes with binary functional monomer for the solid-phase extraction of erythromycin from chicken muscle. | 2011 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21498135 |
| Del Grosso M et al. | Genetic resistance elements carrying mef subclasses other than mef(A) in Streptococcus pyogenes. | 2011 | Antimicrob. Agents Chemother. | pmid:21502613 |
| Loreto ES et al. | In vitro susceptibility of Pythium insidiosum to macrolides and tetracycline antibiotics. | 2011 | Antimicrob. Agents Chemother. | pmid:21537028 |
| Nakamura PA et al. | Antimicrobial resistance profiles and genetic characterisation of macrolide resistant isolates of Streptococcus agalactiae. | 2011 | Mem. Inst. Oswaldo Cruz | pmid:21537668 |
| Shaala LA et al. | Brominated arginine-derived alkaloids from the red sea sponge Suberea mollis. | 2011 | J. Nat. Prod. | pmid:21542602 |
| Zhao DL et al. | Characterization of a cryptic plasmid pSM429 and its application for heterologous expression in psychrophilic Pseudoalteromonas. | 2011 | Microb. Cell Fact. | pmid:21542941 |
| Chen HX et al. | [Compound erythromycin sustained release preparation and its in vitro release]. | 2011 | Yao Xue Xue Bao | pmid:22260035 |
| Wei Z et al. | [Treatment of low-dose erythromycin and sinus displacement on sinusitis in patients with nasopharyngeal carcinoma after radiotherapy]. | 2011 | Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:22260078 |
| Li Y et al. | Molecular characterization of erm(B)- and mef(E)-mediated erythromycin-resistant Streptococcus pneumoniae in China and complete DNA sequence of Tn2010. | 2011 | J. Appl. Microbiol. | pmid:20961364 |
| Vuppalanchi R et al. | Drug-induced QT prolongation in cirrhotic patients with transjugular intrahepatic portosystemic shunt. | 2011 | J. Clin. Gastroenterol. | pmid:20962670 |