erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
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Authors | Title | Published | Journal | PubMed Link |
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Agouridas C et al. | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. | 1998 | J. Med. Chem. | pmid:9767644 |
Vizel' AA et al. | [Antibiotic sensitivity of pathogenic microflora: data of the bacteriological laboratory at the antituberculosis clinic]. | 1998 | Probl Tuberk | pmid:9771042 |
Rosenthal SL and Freundlich LF | In vitro antibiotic sensitivity of Pasteurella multocida. | 1976 | Health Lab Sci | pmid:977341 |
Leroyer C et al. | Dirithromycin concentrations in bronchial mucosa and secretions. | 1998 | Respiration | pmid:9782221 |
Brünker P et al. | Genetic engineering of an industrial strain of Saccharopolyspora erythraea for stable expression of the Vitreoscilla haemoglobin gene (vhb). | 1998 | Microbiology (Reading, Engl.) | pmid:9782491 |
Jacobsen JR et al. | Precursor-directed biosynthesis of 12-ethyl erythromycin. | 1998 | Bioorg. Med. Chem. | pmid:9784859 |
Yanagisawa M et al. | [Effective treatment in combination with erythromycin and cisapride for chronic idiopathic intestinal pseudo-obstruction (CIIP)]. | 1998 | Nihon Shokakibyo Gakkai Zasshi | pmid:9785893 |
Cimolai N | Mycoplasma pneumoniae respiratory infection. | 1998 | Pediatr Rev | pmid:9785929 |
Schülin T et al. | In-vitro activity of the new ketolide antibiotic HMR 3647 against gram-positive bacteria. | 1998 | J. Antimicrob. Chemother. | pmid:9786468 |
Saenko VF et al. | [The influence of macrolides on the motor function of the gastrointestinal duct]. | 1998 | Klin Khir | pmid:9787571 |