erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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LYSTAD A et al. | THE BACTERIAL FLORA OF SINUSITIS WITH AN IN VITRO STUDY OF THE BACTERIAL RESISTANCE TO ANTIBIOTICS. | 1964 | Acta Otolaryngol Suppl | pmid:14146702 |
Hashiba M and Baba S | Efficacy of long-term administration of clarithromycin in the treatment of intractable chronic sinusitis. | 1996 | Acta Otolaryngol Suppl | pmid:8908275 |
Erythromycin, past, present and future. Symposium, Vettere Konferense- og Studiesenter, Asker , Norway, September 16, 1983. | 1984 | Acta Otolaryngol Suppl | pmid:6594027 | |
Frøland SS | Legionella pneumonia--a neglected diagnosis? | 1984 | Acta Otolaryngol Suppl | pmid:6594028 |
Jerve F | Treatment of genital tract infections due to Chlamydia trachomatis. | 1984 | Acta Otolaryngol Suppl | pmid:6594029 |
Sundberg L et al. | Penetration of erythromycin through respiratory mucosa. A study using secretory otitis media as a model. | 1979 | Acta Otolaryngol Suppl | pmid:294806 |
Sundberg L | Antibiotic treatment of secretory otitis media. | 1984 | Acta Otolaryngol Suppl | pmid:6388231 |
Sandström I | Neonatal conjunctivitis caused by Chlamydia trachomatis. | 1984 | Acta Otolaryngol Suppl | pmid:6388234 |
Trollfors B | Whooping cough--aspects of pathogenesis and treatment. | 1984 | Acta Otolaryngol Suppl | pmid:6093425 |
Enomoto F et al. | Effect of erythromycin on otitis media with effusion in experimental rat model. | 1998 | Acta Otolaryngol Suppl | pmid:10095863 |