erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Hawiger J and Jeljaszewicz J | Antibiotic sensitivity of Micrococcus radiodurans. | 1967 | Appl Microbiol | pmid:4166078 |
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Yourassowsky E | [Kinetics of the action of antibiotics in plasma medium]. | 1967 | Acta Clin Belg | pmid:5594390 |
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SamoÄlovich NN | [Sensitivity to antibiotics of pyogenic Staphylococci isolated from hospitalized and ambulatory patients]. | 1967 | Antibiotiki | pmid:5595923 |
Garrison DW et al. | Comparison of in vitro antibacterial activities of 7-chloro-7-deoxylincomycin, lincomycin, and erythromycin. | 1967 | Antimicrob Agents Chemother (Bethesda) | pmid:5596165 |
Apirion D | Three genes that affect Escherichia coli ribosomes. | 1967 | J. Mol. Biol. | pmid:4870510 |
Duncan IB | Development of lincomycin resistance by staphylococci. | 1967 | Antimicrob Agents Chemother (Bethesda) | pmid:5596212 |
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Garanin BA | [Sensitivity toward antibiotics of enteropathogenic Escherichia coli. (According to data from a hospital for infectious diseases)]. | 1967 | Antibiotiki | pmid:4871267 |
Segal J | [Clinico-paracytological and therapeutic study with a new preparation of erythromycin stearate of controlled release (A-16535) in intestinal amebiasis]. | 1967 | Rev Bras Med | pmid:5603001 |
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Blinov NO and Khokhlov AS | [Paper chromatography and electrophoresis in the study of the transformation of antibiotics in the human and animal body]. | 1967 | Antibiotiki | pmid:4874768 |
Maichuk IuF | [Antibiotics in polyvinyl alcohol film for treatment of infectious eye diseases]. | 1967 | Antibiotiki | pmid:4874770 |
Wagner JG and Metzler CM | Estimation of rate constants for absorption and elimination from blood concentration data. | 1967 | J Pharm Sci | pmid:6032790 |
Popovici GG et al. | The influence of some antibiotics on uterine motor activity in the guinea pig. | 1967 | Arch Int Pharmacodyn Ther | pmid:6034322 |
Scanlon RT and Nemes JL | Efficacy and acceptability of erythromycin oral preparations for pediatric practice. | 1967 | Med Ann Dist Columbia | pmid:5232908 |
Myers WH | A comparative trial of Erythroped versus penicillin V. | 1967 | Br J Clin Pract | pmid:4963172 |
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Wilhelm JM and Corcoran JW | Antibiotic glycosides. VI. Definition of the 50s ribosomal subunit of Bacillus subtilis 168 as a major determinant of sensitivity to erythromycin A. | 1967 | Biochemistry | pmid:4963466 |
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Gori E | [A method for the quantitative determination of the effects of drug combinations, applied to antibiotics]. | 1967 | Pathol Biol | pmid:4963681 |
Novick RP and Morse SI | In vivo transmission of drug resistance factors between strains of Staphylococcus aureus. | 1967 | J. Exp. Med. | pmid:6016896 |
Shepard MC | Cultivation and properties of T-strains of mycoplasma associated with nongonococcal urethritis. | 1967 | Ann. N. Y. Acad. Sci. | pmid:5233783 |
Benzi G et al. | Action of some antibiotics on the extra-hepatic biliary tract. II. Erythromycin. | 1967 | Arch Int Pharmacodyn Ther | pmid:4964218 |
Firor WB | Infection following open-heart surgery, with special reference to the role of prophylactic antibiotics. | 1967 | J. Thorac. Cardiovasc. Surg. | pmid:6019151 |
Stelińska A et al. | [Observations on the effectiveness of erythromycin activity on the bacterial flora of dental origin]. | 1967 | Czas Stomatol | pmid:5234368 |
Grönroos JA et al. | A study of liver function during erythromycin estolate treatment. | 1967 | Curr Ther Res Clin Exp | pmid:4965452 |
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Merklen FP and Renoux M | [Antibiotics other than penicillin in the treatment of syphilis]. | 1967 | Rev Fr Odontostomatol | pmid:5235420 |
Benzi G et al. | Action of some antibiotics on the extra-hepatic biliary tract. 3. Tetracyclines. | 1967 | Arch Int Pharmacodyn Ther | pmid:4965568 |
Smith CB et al. | Shedding of Mycoplasma pneumoniae after tetracycline and erythromycin therapy. | 1967 | N. Engl. J. Med. | pmid:6023234 |
Kalowski M and Romankiewicz GE | [Effect of penicillin and erythromycin on the inhibition of rampant dental caries in golden hamsters]. | 1967 | Czas Stomatol | pmid:5235543 |
Cundliffe E and McQuillen K | Bacterial protein synthesis: the effects of antibiotics. | 1967 | J. Mol. Biol. | pmid:4965676 |
Monnier J and Bourse R | [Cross-resistance in macrolids and related groups]. | 1967 | Pathol Biol | pmid:4867325 |
Leonard JR | Prophylactic antibiotics in human stapedectomy. | 1967 | Laryngoscope | pmid:6023620 |
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Purcell RH and Chanock RM | Role of mycoplasmas in human respiratory disease. | 1967 | Med. Clin. North Am. | pmid:6023805 |
Haraguchi I et al. | [Clinico-pathological study on the effect of erythromycin on pulp tissue]. | 1967 | Shikwa Gakuho | pmid:5236258 |
McGovern JP et al. | Bacterial infection in children with respiratory allergy: bacteriologic findings and therapy. | 1967 | South. Med. J. | pmid:6024614 |
Takei M et al. | [Studies on the mixed culture of Candida and Lactobacillus. 3. Influences of the antibiotics (EM and TM)]. | 1967 | Aichi Gakuin Daigaku Shigakkai Shi | pmid:5236280 |
Chang FN and Weisblum B | The specificity of lincomycin binding to ribosomes. | 1967 | Biochemistry | pmid:6025566 |
Molan PC and Hartles RL | The source of glycolytic activity in human saliva. | 1967 | Arch. Oral Biol. | pmid:5237340 |
Rosenberg IH et al. | Abnormal bile-salt patterns and intestinal bacterial overgrowth associated with malabsorption. | 1967 | N. Engl. J. Med. | pmid:6026403 |
Wassermann D | Acute paranasal sinusitis and cavernous sinus thrombosis. | 1967 | Arch Otolaryngol | pmid:6029348 |
Cernea P and Devien CV | [Therapeutic value of a new comined antibiotic therapy]. | 1967 | Rev Fr Odontostomatol | pmid:5238749 |
Kislak JW | Type 6 pneumococcus resistant to erythromycin and lincomycin. | 1967 | N. Engl. J. Med. | pmid:4381364 |
Zagar Z | [Antimicrobial therapy and public health]. | 1967 | Wien. Klin. Wochenschr. | pmid:5185251 |
Dadswell JV | Bacteriological findings in acute otitis media. | 1967 | Lancet | pmid:4163147 |
Prokhorov BS | [Sensitivity to antibiotics and phagolytic properties of staphylococcal strains, isolated from patients]. | 1967 | Antibiotiki | pmid:5187281 |
Shneerson AN | [On the heterogenicity of the population of clinical strains of Staphylococci in relation to their sensitivity to polysynthetic penicillins and macrolide antibiotics]. | 1967 | Antibiotiki | pmid:5187299 |
Gutman LT et al. | Bacterial L-forms in relapsing urinary-tract infection. | 1967 | Lancet | pmid:4164065 |
Weisblum B | Pneumococcus resistant to erythromycin and lincomycin. | 1967 | Lancet | pmid:4164310 |
Jensen K | [Combination therapy with antibacterial chemotherapeutic agents in staphylococcal infections]. | 1967 | Ugeskr. Laeg. | pmid:5187979 |
Slotkin RI et al. | The effect of antibiotics on Mycoplasma pneumoniae in vitro and in vivo. | 1967 | Am. J. Epidemiol. | pmid:5006447 |
Sugano T et al. | [Results in the combined use of nalidixic acid with other drugs for bacillary dysentery]. | 1967 | Nihon Densenbyo Gakkai Zasshi | pmid:4968896 |
Jedlicková Z | [Contribution to the study of the sensitivity of staphylococci toward so-called anti-staphylococcal-antibiotics]. | 1967 | Arzneimittelforschung | pmid:4971496 |
Legler F | [Present resistance status of Staphylococcus aureus under specific consideration of the antibiotics virgimycia, cephalothin and fusidic acid]. | 1967 | Arzneimittelforschung | pmid:4974419 |
Novick R | Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus. | 1967 | Virology | pmid:4227577 |
Lucas JB and Price EV | Co-operative evaluation of treatment for early syphilis. Preliminary report with special reference to spectinomycin sulphate (actinospectacin). | 1967 | Br J Vener Dis | pmid:4230278 |
Luba J and Ulikowski S | [Effect of bacterial infections of fermentative medium on erythromycin biosynthesis]. | 1967 | Acta Pol Pharm | pmid:5583960 |
Olsen H | The sensitivity of Flavobacterium meningosepticum to antibiotics at different temperatures. An in vitro study. | 1967 | Acta Pathol Microbiol Scand | pmid:5584517 |
Balashova II and Khomiakova VI | [Treatment of staphylococcal infections in children by monomycin, neomycin, erythromycin and oletetrin]. | 1967 | Antibiotiki | pmid:5585720 |
Heydenreich A | [Intraocular application of antibiotics]. | 1967 | Klin Monbl Augenheilkd | pmid:5586135 |
Nussbaumer PA | [A contribution to the study of erythromycin by means of thin-layer chromatography. 1. Stability in aquenous medium]. | 1967 | Pharm Acta Helv | pmid:5586792 |
Voiculescu M et al. | [Sensitivity of beta-hemolytic streptococcus, group A, isolated from streptococcal infections, to different antibiotics and sulfonamides]. | 1967 | Schweiz Med Wochenschr | pmid:5587438 |
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Hughes WT and Wan RT | Impetigo contagiosa: etiology, complications, and comparison of therapeutic effectiveness of erythromycin and antibiotic ointment. | 1967 | Am. J. Dis. Child. | pmid:4290285 |
Villaveces JW | Food emulsion therapy: an adverse reaction. | 1967 | Ann Allergy | pmid:6077385 |
Kotula Z and Kamińska A | [Use of paper electrophoresis and thin layer chromatography on talc for erythromycin distribution]. | 1967 | Med Dosw Mikrobiol | pmid:6079142 |
Ozawa A | [On the sensitivity of clinically isolated bacterial strains to aminobenzyl and methylphenylisoxazolyl penicillins, with special reference to urinary tract and bile infections]. | 1967 | J Antibiot B | pmid:4866094 |
Bourse R and Monnier J | [Effect of rythromycin on the growth of "dissociated resistant" Staph. aureus in bacteriostasis from another macrolide or a related antibiotic]. | 1967 | Ann Inst Pasteur (Paris) | pmid:6079710 |
Linnane AW and Stewart PR | The inhibition of chlorophyll formation in Euglena by antibiotics which inhibit bacterial and mitochondrial protein synthesis. | 1967 | Biochem. Biophys. Res. Commun. | pmid:5298473 |
Satgé P et al. | [Generalized infections by Candida albicans in children (apropos of 17 cases)]. | 1967 | Sem Hop | pmid:4296493 |
Arai S et al. | Effect of antibiotics on the growth of various strains of Mycoplasma. | 1967 | J. Antibiot. | pmid:4170543 |
Shikata T et al. | [Intraperitoneal administration of erythromycin glucoheptonate and 5-methyl-3-sulfanilamidoisoxazole and peritoneal adhesion]. | 1967 | J Antibiot B | pmid:5299960 |
Kharitonova AM | [On the nephrotic action of antibiotics]. | 1967 | Antibiotiki | pmid:4171895 |
Medeiros J et al. | [A-16535 in the treatment of chronic intestinal amebiasis]. | 1967 | Hospital (Rio J) | pmid:5302541 |
Spitzy KH | [On the treatment of chronic surgical infections]. | 1967 | Chirurg | pmid:4297172 |
Mehta BM et al. | Evidence of genetic transformation in Streptococcus faecium var. durans (SF-O). | 1967 | J. Bacteriol. | pmid:6051354 |
Krauer-Mayer B | [Antibacterial therapy in the newborn infant]. | 1967 | Z Kinderheilkd | pmid:4297705 |
Golenia A and Rafińska J | [Contribution to the treatment of staphylococcal pericarditis]. | 1967 | Pediatr Pol | pmid:6052305 |
Treatment of atypical pneumonia. | 1967 | Med Lett Drugs Ther | pmid:6052695 | |
Armstrong BK and Curnow DH | The effect of streptomycin and erythromycin on vitamin B12 nutrition in rats in which coprophagy was prevented. | 1967 | Br. J. Nutr. | pmid:6052871 |
Otten H | [Fundamentals and development of chemotherapy for bacterial infections]. | 1967 | Internist (Berl) | pmid:4298330 |
Manchester KL | Effects of antibiotics of protein synthesis in muscle and implications with regard to the action of insulin. | 1967 | Nature | pmid:6053821 |
Gol'dat SIu et al. | [Achievements of Soviet selection of strains--producers of antibiotics]. | 1967 | Antibiotiki | pmid:4298569 |
Münchow P | [Antibiotics 19]. | 1967 | Pharm Prax | pmid:4177256 |
Shneerson AN and Rezvan SP | [Staphylococci resistant to semisynthetic penicillins, isolated from patients]. | 1967 | Antibiotiki | pmid:4298633 |
Khokhlov AS | [Development of antibiotic chemistry in the USSR]. | 1967 | Antibiotiki | pmid:4299071 |
Chernomordik AB | [Synergistic action of antibiotics on Bacillus pyocianaeus]. | 1967 | Antibiotiki | pmid:4300088 |
Lantos J | Change in the phage type of Staphylococcus aureus as a result of lysogenizatio. | 1967 | Acta Microbiol Acad Sci Hung | pmid:4300285 |
DoutlÃk S et al. | Electroencephalographic changes after intravenous administration of antibiotics. | 1967 | Arzneimittelforschung | pmid:4300334 |
von Wasielewski E and Schütze E | [Treatment with antibiotic agents with special reference to their relation to otorhinolaryngology]. | 1967 | Arch Klin Exp Ohren Nasen Kehlkopfheilkd | pmid:4300371 |