erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Uterine Cervical Erosion D002579 2 associated lipids
Uterine Cervical Incompetence D002581 3 associated lipids
Chancroid D002602 4 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Choanal Atresia D002754 1 associated lipids
Cholelithiasis D002769 16 associated lipids
Cholestasis D002779 23 associated lipids
Choline Deficiency D002796 16 associated lipids
Chorioamnionitis D002821 5 associated lipids
Choroiditis D002833 1 associated lipids
Chronic Disease D002908 7 associated lipids
Cleft Palate D002972 9 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Common Cold D003139 2 associated lipids
Compartment Syndromes D003161 1 associated lipids
Conjunctivitis D003231 7 associated lipids
Conjunctivitis, Bacterial D003234 3 associated lipids
Conjunctivitis, Inclusion D003235 4 associated lipids
Constipation D003248 8 associated lipids
Corneal Diseases D003316 13 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Crohn Disease D003424 12 associated lipids
Cross Infection D003428 9 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Dacryocystitis D003607 1 associated lipids
Death, Sudden D003645 12 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Dermatitis D003872 30 associated lipids
Drug Eruptions D003875 30 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Diarrhea D003967 32 associated lipids
Diarrhea, Infantile D003968 3 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Diphtheria D004165 2 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Dry Socket D004368 3 associated lipids
Duodenitis D004382 4 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Dysarthria D004401 2 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Dyspepsia D004415 5 associated lipids
Dyspnea D004417 10 associated lipids
Edema D004487 152 associated lipids
Elephantiasis D004604 2 associated lipids
Empyema D004653 3 associated lipids
Endocarditis D004696 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Sun W et al. [Glycosyl isomerization based on the biosynthesis of natural-product sugar from microorganism]. 2013 Yao Xue Xue Bao pmid:23672013
Chen SX et al. [Synthesis and antibacterial activity of 3-hydroxy-6-O-methylerythromycin-9-O-substituted oxime derivatives]. 2001 Yao Xue Xue Bao pmid:12579933
Watanabe Y et al. [Relationship between quality and serum level after the oral administration of commercial erythromycin tablets in man (author's transl)]. 1977 Yakugaku Zasshi pmid:911413
Matsuoka M [Study of macrolide, lincosamide, and streptogramin B antibiotics resistance in Staphylococcus aureus]. 2000 Yakugaku Zasshi pmid:10774259
Nakamura H et al. Effect of particle size on mixing degree in dispensation. 2004 Yakugaku Zasshi pmid:15049131
Nakamura H et al. Effect of mixing method on the mixing degree during the preparation of triturations. 2004 Yakugaku Zasshi pmid:15049130
Watanabe Y et al. [Effect of dissolving pH of enteric coating agent on bioavailability of enteric coated tablets of erythromycin in man (author's transl)]. 1978 Yakugaku Zasshi pmid:30834
Miyazaki M et al. [Trends and antimicrobial susceptibilities of clinical methicillin-resistant Staphylococcus aureus isolates in Fukuoka University Chikushi Hospital 2008-2012]. 2014 Yakugaku Zasshi pmid:24492229
Otsuka M et al. [Studies on fungicides. XIV. Effect of erythromycin on the growth of fungal mycelia (author's transl)]. 1978 Yakugaku Zasshi pmid:566318
Zhang Y et al. [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2]. 2014 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:24721407
Yamazaki H et al. Effects of roxithromycin, erythromycin and troleandomycin on their N-demethylation by rat and human cytochrome P450 enzymes. 1996 Xenobiotica pmid:8948090
Pasic J et al. The interaction between chronic oral slow-release theophylline and single-dose intravenous erythromycin. 1987 Xenobiotica pmid:3604256
Yamazaki H and Shimada T Formation in vitro of an inhibitory cytochrome P450 x Fe2+-metabolite complex with roxithromycin and its decladinosyl, O-dealkyl and N-demethyl metabolites in rat liver microsomes. 1998 Xenobiotica pmid:9849646
Saitoh R et al. Nonlinear intestinal pharmacokinetics of mitemcinal, the first acid-resistant non-peptide motilin receptor agonist, in rats. 2007 Xenobiotica pmid:17926229
Villa P et al. Erythromycin toxicity in primary cultures of rat hepatocytes. 1985 Aug-Sep Xenobiotica pmid:4072263
Ward KW et al. Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human. 2005 Xenobiotica pmid:16019946
Molnari JC and Myers AL Carbonyl reduction of bupropion in human liver. 2012 Xenobiotica pmid:22339467
Kaye B and Roberts DW The metabolism of oxamniquine in the gut wall. 1980 Xenobiotica pmid:7395269
Guillouzo A et al. Human hepatocyte cultures: a model of pharmaco-toxicological studies. 1985 Aug-Sep Xenobiotica pmid:3907158
Kanazu T et al. Model for the drug-drug interaction responsible for CYP3A enzyme inhibition. I: evaluation of cynomolgus monkeys as surrogates for humans. 2004 Xenobiotica pmid:15370956