erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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SamoÄlovich NN | [Sensitivity to antibiotics of pyogenic Staphylococci isolated from hospitalized and ambulatory patients]. | 1967 | Antibiotiki | pmid:5595923 |
Grönroos JA et al. | A study of liver function during erythromycin estolate treatment. | 1967 | Curr Ther Res Clin Exp | pmid:4965452 |
Smith CB et al. | Shedding of Mycoplasma pneumoniae after tetracycline and erythromycin therapy. | 1967 | N. Engl. J. Med. | pmid:6023234 |
Vasil'eva NG and Poliak MS | [Microflora of sputum in pneumonias and its sensitivity to antibiotics]. | 1967 | Antibiotiki | pmid:4386255 |
Zegarelli EV et al. | Discoloration of the teeth in a 24-year-old patient with cystic fibrosis of the pancreas not primarily associated with tetracycline therapy. Report of a case. | 1967 | Oral Surg. Oral Med. Oral Pathol. | pmid:4291199 |
Warren GH and Gray J | Effect of antimicrobial drug combinations on enzymic lysis of Staphylococcus aureus. | 1967 | Proc. Soc. Exp. Biol. Med. | pmid:6066156 |
Tarizzo ML and Nabli B | The effect of antibiotics on the growth of TRIC agents in embryonated eggs. | 1967 | Am. J. Ophthalmol. | pmid:6067315 |
Saslaw S and Carlisle HN | Studies on therapy of staphylococcal infections in monkeys. I. Comparison of cloxacillin, triacetyloleandomycin and erythromycin. | 1967 Aug-Sep | Proc. Soc. Exp. Biol. Med. | pmid:4962963 |
Rdzanek I and Weyman-Rzucidlo D | [Recent views on the etiology and therapy of erythrasma]. | 1967 Jan-Feb | Przegl Dermatol | pmid:6044676 |
Moro S | [In vitro sensitivity to antibiotics of spores of Plectridium tetani]. | 1967 Jan-Feb | G Batteriol Virol Immunol | pmid:4899675 |
ArcalÃs L and Caldés J | [Report on the antibiotic activity of the DAN-352 compound]. | 1967 Jul-Dec | Microbiol Esp | pmid:5619843 |
Teodorovici G et al. | [Evolution of the antibiotic sensitivity of pathogenic staphylococci isolated in rural areas]. | 1967 Jul-Sep | Rev Med Chir Soc Med Nat Iasi | pmid:5195743 |
Timsit E | [Results obtained with erythromycin stearate in the treatment of acnes]. | 1967 Jun-Jul | Sem Ther | pmid:4240940 |
Serene TP and Anderson DL | Isolation of mycoplasma from human root canals. | 1967 Mar-Apr | J. Dent. Res. | pmid:5228073 |
Evdoshchenko EA et al. | [Treatment of cochlear neuritis]. | 1967 May-Jun | Zh Ushn Nos Gorl Bolezn | pmid:5621389 |
Molina Pasquel C et al. | [Treatment of intestinal amebiasis using erythromycin stearate of normal release with enteric coating (A-16535). Study of 13 cases. Preliminary report]. | 1967 Oct-Dec | Rev Invest Salud Publica | pmid:5618959 |
Cundliffe E and McQuillen K | Peptide bond formation: the effects of antibiotics on the puromycin reaction. | 1968 | J. Gen. Microbiol. | pmid:4968006 |
Cundliffe E and McQuillen K | Peptide-bond formation: the modes of action of chloramphenicol, sparsomycin and erythromycin. | 1968 | J. Gen. Microbiol. | pmid:4968007 |
Cerná J and RychlÃk I | Cross resistance of Escherichia coli B ribosomes to inhibition of the puromycin reaction by erythromycin, spiramycin and chloramphenicol. | 1968 | Biochim. Biophys. Acta | pmid:4870247 |
Shipley A et al. | T-strain mycoplasmas in non-specific urethritis. | 1968 | Med. J. Aust. | pmid:4872365 |
MosiÄchuk NM | [Permeability of the hemato-encephalic barrier to antibiotics in patients with infectious meningitis]. | 1968 | Zh Nevropatol Psikhiatr Im S S Korsakova | pmid:4872691 |
Aoki Y | Colicin type, biochemical type and drug-resistance pattern of Shigella sonnei isolated in Japan and its neighboring countries. | 1968 | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:4874474 |
Garanin BA | [Analysis of the sensitivity toward some antibiotics of Salmonellas isolated from patients during 1960-1966]. | 1968 | Antibiotiki | pmid:4876633 |
Sanders E et al. | Group A beta-hemolytic streptococci resistant to erythromycin and lincomycin. | 1968 | N. Engl. J. Med. | pmid:4966066 |
Ross S | Erythromycin, oleandomycin and triacetyloleandomycin. | 1968 | Pediatr. Clin. North Am. | pmid:4867776 |
Mao JC and Putterman M | Accumulation in gram-postive and gram-negative bacteria as a mechanism of resistance to erythromycin. | 1968 | J. Bacteriol. | pmid:4966821 |
Ferrando R | [Absorption and metabolism of antibiotics. Residues in the tissues]. | 1968 | Bibl Nutr Dieta | pmid:4868400 |
Frisby BR | A laboratory comparison of tri-acetyl oleandomycin and nine other antibiotics. | 1968 | Med. J. Aust. | pmid:4967052 |
Lindsay AE and Truxal AC | Oral therapy in bacterial endocarditis. | 1968 | Rocky Mt Med J | pmid:4967211 |
Oleinick NL et al. | Nonidentity of the site of action of erythromycin A and chloramphenicol on Bacillus subtilis ribosomes. | 1968 | Biochim. Biophys. Acta | pmid:4967315 |
Lang N et al. | On the mechanism of hormone action. VII. Induction by cortisol of a messenger RNA coding for tyrosine-alpha-ketoglutarate transaminase for an in vitro system. | 1968 | Acta Endocrinol. | pmid:4384442 |
Gurney T and Fox MS | Physical and genetic hybrids formed in bacterial transformation. | 1968 | J. Mol. Biol. | pmid:4384454 |
Osman HG et al. | Utilization of Egyptian raw by-products for the erythromycin production by Streptomyces erythreus. | 1968 | Z. Allg. Mikrobiol. | pmid:4989340 |
Henriksen SD and Bovre K | Moraxella kingii sp.nov., a haemolytic, saccharolytic species of the genus Moraxella. | 1968 | J. Gen. Microbiol. | pmid:5185818 |
Choudhuri KK and Basu Mallick KC | Study of antibiotic-resistant staphylococci isolated from different sources and their role in pathogenicity. | 1968 | Indian J. Med. Res. | pmid:5186305 |
Robertson MH | Tetracycline-resistant streptococci in South-west Essex: a continuing survey. | 1968 | Br Med J | pmid:5186976 |
Postnikova AA | [On the characteristics of staphylococci in chronic osteomyelitis in children]. | 1968 | Antibiotiki | pmid:5187169 |
Obojska K and Zawadzka-Gralewicz J | [Combined effect of colistin with neomycin, penicillins and erythromycin on Corynebacterium diphtheriae]. | 1968 | Med Dosw Mikrobiol | pmid:4970248 |
Sabath LD et al. | Enhancing effect on alkalinization of the medium on the activity of erythromycin against gram-negative bacteria. | 1968 | Appl Microbiol | pmid:4970991 |
Jewett JF et al. | Childbed fever--a continuing entity. | 1968 | JAMA | pmid:4971028 |
Iats'ko VA | [On the dynamics of sensitivity to antibiotics of different microorganisms, isolated from patients of a surgical section]. | 1968 | Antibiotiki | pmid:4971186 |
Betinová M | [Effect of tetracyclines, macrolide antibiotics, and sigmamycin on staphylococci in vitro]. | 1968 | Biologia | pmid:4971503 |
Erythromycin compared with phenoxymethyl-penicillin and tetracycline. | 1968 | Practitioner | pmid:4972106 | |
Ahmed A | Altered ribosomes in spiramycin-resistant mutants of Bacillus subtilis. | 1968 | Biochim. Biophys. Acta | pmid:4972350 |
De Vries JA et al. | Adjunctive use of antibiotics in traumatic dental procedures. | 1968 | Int Z Klin Pharmakol Ther Toxikol | pmid:4972570 |
Fekety FR | Gastrointestinal complications of antibiotic therapy. | 1968 | JAMA | pmid:5694045 |
Jackson DM | The burnt child and his family. What the burnt child goes through. | 1968 | Proc. R. Soc. Med. | pmid:4972634 |
Tramier G et al. | [Matinal urethral discharge and terminal male urethritis]. | 1968 | Bull Soc Fr Dermatol Syphiligr | pmid:5702616 |
Ramos e Silva J | [Current treatment of syphilis, particularly of early syphilis]. | 1968 | Rev Bras Med | pmid:5707186 |
Hejzlar M et al. | Ten-year study of Neisseria gonorrhoeae sensitivity to antibiotics in Czechoslovakia. | 1968 | J Hyg Epidemiol Microbiol Immunol | pmid:4977454 |
Ocklitz HW et al. | [Pediatric guidelines. 3. Antibiotics--indications]. | 1968 | Z Arztl Fortbild (Jena) | pmid:4978334 |
Magliulo E et al. | [Effects of a lysozyme-antibiotic combination on the phagocytic activity of human neutrophil granulocytes]. | 1968 | Arch Sci Med (Torino) | pmid:5733616 |
Weinstein MJ et al. | Preliminary studies on megalomicin, a new Micromonospora-produced macrolide antibiotic complex. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735370 |
Paterson PY and Madden GM | Occurrence and erythromycin susceptibility of penicillin-resistant Viridans streptococci in rheumatic fever patients on oral penicillin prophylaxis. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735376 |
McGehee RF R et al. | Resistance of Staphylococcus aureus to lincomycin, clinimycin, and erythromycin. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735385 |
Wick WE and Mallett GE | New analysis for the therapeutic efficacy opropionyl erythromycin and erythromycin base. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735386 |
Kuntsevich LD | [Erythromycin and oleandomycin in therapy of fresh gonorrhea in women]. | 1968 | Vestn Dermatol Venerol | pmid:5738081 |
Pezzìca R | [Damage caused by associated antibiotics in domiciliary therapy of acute febrile diseases. Film: "These 3 neutrophil leukocytes are from a 4-year-old child on the fourth day of treatment with CAF in average therapeutic doses. The toxic granulations in the protoplasm are clearly visible"]. | 1968 | Minerva Pediatr. | pmid:5739033 |
Renzini G et al. | [Study of the antibacterial activity and of the serum and tissue levels produced in animals by the administration of two antibiotic associations]. | 1968 | Antibiotica | pmid:5740898 |
Studnitsin AA and Pashkov BM | [Results of discussions on the treatment of syphilis]. | 1968 | Vestn Dermatol Venerol | pmid:5742374 |
Martini J et al. | [Treatment of acute male gonococcal urethritis with a single dosis of erythromycin-stearate]. | 1968 | Rev Med Chil | pmid:5746282 |
Mitsui Y and Suzuki H | [Evaluation of colistin-erythromycin ointment and solution in ophthalmology]. | 1968 | Nihon Ganka Kiyo | pmid:5748900 |
Pulverer G | [Studies with lysostaphin. I. Lysostaphin sensitivity of 355 strains of Staph. aureus of human origin]. | 1968 | Z Med Mikrobiol Immunol | pmid:5710870 |
Puito L | [Antibiotic therapy in infancy]. | 1968 | Pediatria (Napoli) | pmid:4312284 |
Amato Neto V and Wanderley RA | [Use of an erythromycin stearate preparation, of regulated intestinal release in the treatment of intestinal amebiasis]. | 1968 | Hospital (Rio J) | pmid:5311770 |
Morgan IG and Austin L | Synaptosomal protein synthesis in a cell-free system. | 1968 | J. Neurochem. | pmid:4230127 |
Smith CC et al. | Bacterial substitution for staphylococcal infection. | 1968 | N. Z. Med. J. | pmid:4231513 |
Bülow P | A new epidemic phage type of Staphylococcus aureus. I. The experimental typing phage 6557'. | 1968 | Acta Pathol Microbiol Scand | pmid:4231992 |
Bülow P | A new epidemic phage type of Staphylococcus aureus. 2. Characteristics of staphylococci lysed by phage 6557'. | 1968 | Acta Pathol Microbiol Scand | pmid:4231993 |
Breitfellner G and Neuhold R | [Yearly variations of the lysotype and resistance picture of staphylococci]. | 1968 | Wien. Klin. Wochenschr. | pmid:4232544 |
Beck LE | Some recent advances and trends in drug therapy. 2. Antibiotics. | 1968 | Med. J. Aust. | pmid:4233563 |
Jayaraman J and Goldberg IH | Localization of sparsomycin action to the peptide-bond-forming step. | 1968 | Biochemistry | pmid:4921281 |
Herrschaft H | [On the participation of the central nervous system in Behcet's disease]. | 1968 | Dtsch. Med. Wochenschr. | pmid:5655850 |
Ezekiel DH and Elkins BN | The stimulation of ribonucleic acid synthesis by ribosome inhibitors in amino acid-starved Escherichia coli. | 1968 | Biochim. Biophys. Acta | pmid:4234520 |
Biró L and Iván E | Study of bactericidal and bacteriostatic antibiotics in animals with normal and suppressed immunity. | 1968 | Chemotherapy | pmid:5656115 |
Wyman JB et al. | Pancreatic, hepatic, and renal excretion of antibiotics in dogs. Observations on erythromycin, lincomycin, kanamycin, and colistimethate excretion. | 1968 | Arch Surg | pmid:5657416 |
Hashimoto H et al. | Drug resistance of staphylococci. IX. Inducible resistance to macrolide antibiotics in Staphylococcus aureus. | 1968 | Jpn. J. Microbiol. | pmid:4236812 |
Schmitt BD | Indications for tetracycline in pediatrics. | 1968 | Pediatrics | pmid:5657689 |
Forshaw J | Penicillin-induced granulopenia. | 1968 | Br Med J | pmid:5662555 |
Zabalueva TS et al. | [Sensitivity to antibiotics of staphylococci, isolated in city of Gor'kiu]. | 1968 | Antibiotiki | pmid:4237512 |
Mezey E et al. | Serum alcohol dehydrogenase, an indicator of intrahepatic cholestasis. | 1968 | N. Engl. J. Med. | pmid:5662777 |
Davis CM et al. | The value of neomycin in a neomycin-steroid cream. | 1968 | JAMA | pmid:4294840 |
Levin HS and Kagan BM | Antimicrobial agents: pediatric dosage, routes of administration and preparation procedures for parenteral therapy. | 1968 | Pediatr. Clin. North Am. | pmid:4295551 |
Banaszek A et al. | Thin-layer and column chromatography of erythromycins and some degradation products. | 1968 | J. Chromatogr. | pmid:4295864 |
Martin JR and Perun TJ | Studies on the biosynthesis of the erythromycins. 3. Isolation and structure of 5-deoxy-5-oxoerythronolide B, a shunt metabolite of erythromycin biosynthesis. | 1968 | Biochemistry | pmid:4297053 |
Sanders S and Norman AP | The bacterial flora of the upper respiratory tract in children with severe asthma. | 1968 | J Allergy | pmid:5300899 |
McGehee RF et al. | Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin. | 1968 | Am. J. Med. Sci. | pmid:4386950 |
Oppenheimer S and Turek M | Laboratory and clinical evaluation of 7-chloro-7-deoxylincomycin. | 1968 | Am. J. Med. Sci. | pmid:4386951 |
Bolkhovitinova LA et al. | [Antibiotics in the treatment of burns]. | 1968 | Antibiotiki | pmid:4175285 |
MacLowry JD and Marsh HH | Semiautomatic microtechnique for serial dilution-antibiotic sensitivity testing in the clinical laboratory. | 1968 | J. Lab. Clin. Med. | pmid:4175675 |
Vasarinsh P | Primary cutaneous nocardiosis. | 1968 | Arch Dermatol | pmid:5684220 |
Sabath LD et al. | Serum glutamic oxalacetic transaminase. False elevations during administration of erythromycin. | 1968 | N. Engl. J. Med. | pmid:5686481 |
Rajka G | Treatment of gonorrhoea patients with intolerance to penicillin. | 1968 | Acta Derm. Venereol. | pmid:4177580 |
Grimble AS | Possible Mycoplasma hominis urethritis rvealed by differing responses of "abacterial urethritis" to treatment with tetracycline and erythromycin. | 1968 | Br J Vener Dis | pmid:5687045 |
Weisblum B and Davies J | Antibiotic inhibitors of the bacterial ribosome. | 1968 | Bacteriol Rev | pmid:4179192 |
Ivanitskaia LP and Manafova NA | [Study of sensitivity to antibiotics in cultures of Anacystis nidulans and Chlorella sp. in relation to their possible use as tests in selection of new biologically active compounds from Actinomycetes]. | 1968 | Antibiotiki | pmid:4180805 |
Dohlman CH and Boruchoff SA | Penetrating keratoplasty. | 1968 | Int Ophthalmol Clin | pmid:4904228 |
Siegenthaler W et al. | [New antibiotics, with the exception of penicillins, streptomycin, tetracyclines and chloramphenicol]. | 1968 | Antibiot Chemother | pmid:4302993 |
Minkova GL | [On the sensitivity of microflora of burn wounds to antibiotics]. | 1968 | Antibiotiki | pmid:4305269 |
Baskanchiladze GSh and Buniatova IM | [Change in the sensitivity to antibiotics of pathogenic staphylococci, isolated in Tiflis during 1961-1966]. | 1968 | Antibiotiki | pmid:4303353 |