erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Altomare G et al. | Treatment of bullous pemphigoid with erythromycin: a reappraisal. | 1999 Oct-Nov | Eur J Dermatol | pmid:10610238 |
Czeizel AE et al. | A population-based case-control teratologic study of oral erythromycin treatment during pregnancy. | 1999 Nov-Dec | Reprod. Toxicol. | pmid:10613401 |
Urmösi J | [Thrombophlebitis of the sinus cavernosus]. | 1975 | Stomatol DDR | pmid:1061410 |
National guideline for the management of Chlamydia trachomatis genital tract infection. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616372 | |
National guideline for the management of non-gonococcal urethritis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases) | 1999 | Sex Transm Infect | pmid:10616373 | |
National guideline for the management of early syphilis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616379 | |
National guideline for the management of lymphogranuloma venereum. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616382 | |
National guideline for the management of chancroid. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616383 | |
Chieppa DM et al. | Effects of erythromycin on human colonic circular muscle in idiopathic chronic constipation. | 2000 | Eur. J. Clin. Invest. | pmid:10620004 |
Novikova SI et al. | Introduction of a mini-gene encoding a five-amino acid peptide confers erythromycin resistance on Bacillus subtilis and provides temporary erythromycin protection in Proteus mirabilis. | 2000 | FEMS Microbiol. Lett. | pmid:10620668 |
Desaki M et al. | Erythromycin suppresses nuclear factor-kappaB and activator protein-1 activation in human bronchial epithelial cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10623585 |
Kdesh A et al. | Effect of erythromycin on myocardial repolarization in patients with community-acquired pneumonia. | 1999 | South. Med. J. | pmid:10624910 |
Gallardo MA and Thomas I | Hypersensitivity reaction to erythromycin. | 1999 | Cutis | pmid:10626100 |
Lagrou K et al. | Macrolide resistance in Belgian Streptococcus pneumoniae. | 2000 | J. Antimicrob. Chemother. | pmid:10629023 |
GarcÃa Sánchez MJ et al. | [Bacterial resistances]. | 1999 | Aten Primaria | pmid:10630037 |
Sullivan S et al. | Stevens-Johnson syndrome secondary to erythromycin. | 1999 | Ann Pharmacother | pmid:10630839 |
Trinkle R | Comment: evaluation of the clinical and financial impact of intravenous erythromycin therapy in hospitalized patients. | 1999 | Ann Pharmacother | pmid:10630842 |
Puri SK and Singh N | Azithromycin: antimalarial profile against blood- and sporozoite-induced infections in mice and monkeys. | 2000 | Exp. Parasitol. | pmid:10631075 |
Weston WL and Morelli JG | Steroid rosacea in prepubertal children. | 2000 | Arch Pediatr Adolesc Med | pmid:10632252 |
Hypertrophic pyloric stenosis in infants following pertussis prophylaxis with erythromycin--Knoxville, Tennessee, 1999. | 1999 | MMWR Morb. Mortal. Wkly. Rep. | pmid:10634345 |