erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Nasrin D et al. | Antibiotic resistance in Streptococcus pneumoniae isolated from children. | 1999 | J Paediatr Child Health | pmid:10634983 |
MartÃnez-Maldonado M | Postinfectious glomerulonephritis. | 2000 | Am. J. Kidney Dis. | pmid:10636819 |
Wu YJ | Highlights of semi-synthetic developments from erythromycin A. | 2000 | Curr. Pharm. Des. | pmid:10637376 |
Bajic S et al. | Analysis of erythromycin by liquid chromatography/mass spectrometry using involatile mobile phases with a novel atmospheric pressure ionization source. | 2000 | Rapid Commun. Mass Spectrom. | pmid:10637421 |
Gisby J and Bryant J | Efficacy of a new cream formulation of mupirocin: comparison with oral and topical agents in experimental skin infections. | 2000 | Antimicrob. Agents Chemother. | pmid:10639346 |
Brueggemann AB et al. | In vitro activity of ABT-773, a new ketolide, against recent clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. | 2000 | Antimicrob. Agents Chemother. | pmid:10639382 |
Honma Y et al. | Effect of erythromycin on Shigella infection of Caco-2 cells. | 2000 | FEMS Immunol. Med. Microbiol. | pmid:10640609 |
Sharma PK et al. | Erythromycin in pityriasis rosea: A double-blind, placebo-controlled clinical trial. | 2000 | J. Am. Acad. Dermatol. | pmid:10642679 |
Santos R et al. | Bacillary angiomatosis by Bartonella quintana in an HIV-infected patient. | 2000 | J. Am. Acad. Dermatol. | pmid:10642694 |
Lebwohl M et al. | Clinically significant therapeutic interactions for the practicing dermatologist. | 1999 | Adv Dermatol | pmid:10643493 |
Heidenreich A et al. | Gastroparesis after retroperitoneal surgery successfully treated with erythromycin. | 2000 | J. Urol. | pmid:10647677 |
Medhus AW et al. | Low-dose intravenous erythromycin: effects on postprandial and fasting motility of the small bowel. | 2000 | Aliment. Pharmacol. Ther. | pmid:10651665 |
Mackinnon AM | The problem of intrahepatic cholestasis. | 1975 | Aust N Z J Med | pmid:1065291 |
Tsutsumi M et al. | Inhibitory effects of combined administration of antibiotics and anti-inflammatory drugs on lung tumor development initiated by N-nitrosobis(2-hydroxypropyl)amine in rats. | 2000 | Carcinogenesis | pmid:10657965 |
Allevi P et al. | A new convenient transformation of erythromycin A into clarithromycin. | 1999 | Bioorg. Med. Chem. | pmid:10658579 |
Nakahara S et al. | Bronchial amyloidosis successfully treated with low-dose long-term erythromycin therapy. | 1999 | Kurume Med J | pmid:10659597 |
From the Centers for Disease Control and Prevention. Hypertrophic pyloric stenosis in infants following pertussis prophylaxis with erythromycin--Knoxville, Tennessee, 1999. | 2000 | JAMA | pmid:10659863 | |
Descheemaeker P et al. | Macrolide resistance and erythromycin resistance determinants among Belgian Streptococcus pyogenes and Streptococcus pneumoniae isolates. | 2000 | J. Antimicrob. Chemother. | pmid:10660498 |
Wilkinson B et al. | Novel octaketide macrolides related to 6-deoxyerythronolide B provide evidence for iterative operation of the erythromycin polyketide synthase. | 2000 | Chem. Biol. | pmid:10662692 |
Tang L et al. | Formation of functional heterologous complexes using subunits from the picromycin, erythromycin and oleandomycin polyketide synthases. | 2000 | Chem. Biol. | pmid:10662693 |