erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kawai Y et al. | Nationwide surveillance of macrolide-resistant Mycoplasma pneumoniae infection in pediatric patients. | 2013 | Antimicrob. Agents Chemother. | pmid:23716043 |
Gold RM and Lawhon SD | Incidence of inducible clindamycin resistance in Staphylococcus pseudintermedius from dogs. | 2013 | J. Clin. Microbiol. | pmid:24025915 |
Pohl O et al. | Effects of erythromycin at steady-state concentrations on the pharmacokinetics of ulipristal acetate. | 2013 | J Clin Pharm Ther | pmid:24102384 |
Magee TV et al. | Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23414806 |
Lermite E et al. | Complications after pancreatic resection: diagnosis, prevention and management. | 2013 | Clin Res Hepatol Gastroenterol | pmid:23415988 |
Kjær S et al. | Ultrasound-guided drainage of subcutaneous abscesses on the trunk is feasible. | 2013 | Dan Med J | pmid:23651712 |
Elens L et al. | CYP3A4 intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin. | 2013 | Pharmacogenomics | pmid:23327575 |
Lins RX et al. | Antimicrobial resistance and virulence traits of Enterococcus faecalis from primary endodontic infections. | 2013 | J Dent | pmid:23851130 |
Cui B et al. | Differences between two clinical Staphylococcus capitis subspecies as revealed by biofilm, antibiotic resistance, and pulsed-field gel electrophoresis profiling. | 2013 | J. Clin. Microbiol. | pmid:23052315 |
Heelan K et al. | Panton-Valentine leukocidin-producing Staphylococcal aureus: report of four siblings. | 2012 Sep-Oct | Pediatr Dermatol | pmid:21906149 |
Lian W et al. | Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. | 2012 Oct-Dec | Biosens Bioelectron | pmid:22683249 |
Hapa A et al. | Childhood pityriasis lichenoides and oral erythromycin. | 2012 Nov-Dec | Pediatr Dermatol | pmid:22639857 |
Asai N et al. | A successfully treated case of parainfluenza virus 3 pneumonia mimicking influenza pneumonia. | 2012 Nov-Dec | J Bras Pneumol | pmid:23288130 |
Clementson B and Smidt AC | Periorificial dermatitis due to systemic corticosteroids in children: report of two cases. | 2012 May-Jun | Pediatr Dermatol | pmid:22122785 |
Kuhn M et al. | Feed restriction enhances the depressive effects of erythromycin on equine hindgut microbial metabolism in vitro. | 2012 Jul-Aug | Berl. Munch. Tierarztl. Wochenschr. | pmid:22919930 |
Jiang RS et al. | Efficacy of Chinese herbal medicine compared with a macrolide in the treatment of chronic rhinosinusitis without nasal polyps. | 2012 Jul-Aug | Am J Rhinol Allergy | pmid:22801017 |
Kuehne SA and Minton NP | ClosTron-mediated engineering of Clostridium. | 2012 Jul-Aug | Bioengineered | pmid:22750794 |
Miguel AI et al. | Pediatric ocular rosacea: 2 cases. | 2012 Jul-Aug | Eur J Ophthalmol | pmid:22267454 |
Amatya A et al. | Comparative study of effectiveness of oral acyclovir with oral erythromycin in the treatment of Pityriasis rosea. | 2012 Jan-Mar | Kathmandu Univ Med J (KUMJ) | pmid:22971864 |
Zhang H et al. | Improved E. coli erythromycin A production through the application of metabolic and bioprocess engineering. | 2012 Jan-Feb | Biotechnol. Prog. | pmid:21905273 |
Pehr K | Mycophenolate mofetil and erythromycin for bullous lupus erythematosus of childhood. | 2012 Jan-Feb | J Cutan Med Surg | pmid:22417996 |
Waśko A et al. | Genetic mechanisms of variation in erythromycin resistance in Lactobacillus rhamnosus strains. | 2012 | J. Antibiot. | pmid:22948255 |
Counsell H | An abdominal mass in a 4-year-old child. | 2012 | BMJ Case Rep | pmid:22922923 |
Juntunen P et al. | Campylobacter coli isolates from Finnish farrowing farms using aminopenicillins: high prevalence of bla(OXA-61) and β-lactamase production, but low MIC values. | 2012 | Foodborne Pathog. Dis. | pmid:22924522 |
Kwiatkowska B and Maślińska M | Macrolide therapy in chronic inflammatory diseases. | 2012 | Mediators Inflamm. | pmid:22969171 |
Mulholland S et al. | Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children. | 2012 | Cochrane Database Syst Rev | pmid:22972079 |
Rashed SM et al. | Genetic characteristics of drug-resistant Vibrio cholerae O1 causing endemic cholera in Dhaka, 2006-2011. | 2012 | J. Med. Microbiol. | pmid:22977073 |
Mokhber-Dezfooli MR et al. | Effect of abomasal emptying rate on the apparent efficiency of colostral immunoglobulin G absorption in neonatal Holstein-Friesian calves. | 2012 | J. Dairy Sci. | pmid:22981576 |
Leyden JJ | In vivo antibacterial effects of tretinoin-clindamycin and clindamycin alone on Propionibacterium acnes with varying clindamycin minimum inhibitory. | 2012 | J Drugs Dermatol | pmid:23377513 |
Wills RH et al. | Structural characterization of polyketides using high mass accuracy tandem mass spectrometry. | 2012 | Anal. Chem. | pmid:22985101 |
Hess TM and Chew HF | Successful treatment of acute ocular involvement in Stevens-Johnson syndrome with amniotic membrane transplantation: a case report. | 2012 | Can. J. Ophthalmol. | pmid:23217513 |
Sugimoto T et al. | Synthesis and structure-activity relationship of a novel class of 15-membered macrolide antibiotics known as '11a-azalides'. | 2012 | Bioorg. Med. Chem. | pmid:22925450 |
Soeters HM et al. | Trimethoprim-sulfamethoxazole prophylaxis and antibiotic nonsusceptibility in invasive pneumococcal disease. | 2012 | Antimicrob. Agents Chemother. | pmid:22232291 |
Wang L et al. | Persistence of resistance to erythromycin and tetracycline in swine manure during simulated composting and lagoon treatments. | 2012 | Microb. Ecol. | pmid:21811793 |
Sunkara B et al. | Group B Streptococcus infections in non-pregnant adults: the role of immunosuppression. | 2012 | Int. J. Infect. Dis. | pmid:22236484 |
Mansouri-najand L et al. | Prevalence of multidrug resistance Campylobacter jejuni and Campylobacter coli in chickens slaughtered in selected markets, Malaysia. | 2012 | Trop Biomed | pmid:22735845 |
Oo C and Shah B | Does erythromycin have anti-inflammatory effects independent of its antimicrobial action? | 2012 | J Clin Pharmacol | pmid:21868717 |
Janssen BD et al. | Analysis of aminoacyl- and peptidyl-tRNAs by gel electrophoresis. | 2012 | Methods Mol. Biol. | pmid:22736012 |
LeTourneau N et al. | Synthesis and antibacterial activity of desosamine-modified macrolide derivatives. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22738632 |
Harvey CJ et al. | Precursor directed biosynthesis of an orthogonally functional erythromycin analogue: selectivity in the ribosome macrolide binding pocket. | 2012 | J. Am. Chem. Soc. | pmid:22741553 |
März A et al. | Fluorescence dye as novel label molecule for quantitative SERS investigations of an antibiotic. | 2012 | Anal Bioanal Chem | pmid:21822777 |
KurinÄiÄ M et al. | Effects of efflux pump inhibitors on erythromycin, ciprofloxacin, and tetracycline resistance in Campylobacter spp. isolates. | 2012 | Microb. Drug Resist. | pmid:22741576 |
Tran TD et al. | Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibiotics. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22727643 |
Sommerfeld Ross S and Fiegel J | Nutrient dispersion enhances conventional antibiotic activity against Pseudomonas aeruginosa biofilms. | 2012 | Int. J. Antimicrob. Agents | pmid:22727773 |
Zaknoon F et al. | Antibacterial properties of an oligo-acyl-lysyl hexamer targeting Gram-negative species. | 2012 | Antimicrob. Agents Chemother. | pmid:22751534 |
Gant CM et al. | Serotype distribution and antimicrobial resistance of invasive pneumococcal disease strains in the Comunidad Valenciana, Spain, during the winter of 2009-2010: low PCV7 coverage and high levofloxacin resistance. | 2012 | Antimicrob. Agents Chemother. | pmid:22751535 |
Shi JG et al. | The effect of CYP3A4 inhibition or induction on the pharmacokinetics and pharmacodynamics of orally administered ruxolitinib (INCB018424 phosphate) in healthy volunteers. | 2012 | J Clin Pharmacol | pmid:21602517 |
Gokmen T et al. | A controlled trial of erythromycin and UDCA in premature infants during parenteral nutrition in minimizing feeding intolerance and liver function abnormalities. | 2012 | J Perinatol | pmid:21566568 |
GarcÃa-Pérez ME et al. | Picea mariana bark: a new source of trans-resveratrol and other bioactive polyphenols. | 2012 | Food Chem | pmid:22953840 |
De Sousa A and Kalra G | Drug therapy of attention deficit hyperactivity disorder: current trends. | 2012 | Mens Sana Monogr | pmid:22654382 |
Wormser GP et al. | Failure of topical antibiotics to prevent disseminated Borrelia burgdorferi infection following a tick bite in C3H/HeJ mice. | 2012 | J. Infect. Dis. | pmid:21930606 |
Rahube TO and Yost CK | Characterization of a mobile and multiple resistance plasmid isolated from swine manure and its detection in soil after manure application. | 2012 | J. Appl. Microbiol. | pmid:22486928 |
Campelo FA et al. | [Phenotypes and mechanisms of resistance to macrolides and lincosamides in Streptococcus agalactiae isolates with clinical significance in an eight-year period (2002-2010)]. | 2012 | Rev Esp Quimioter | pmid:22488541 |
Imai Y et al. | Development of the ability to produce secondary metabolites in Streptomyces through the acquisition of erythromycin resistance. | 2012 | J. Antibiot. | pmid:22491137 |
Hellmann-Regen J et al. | Retinoic acid as target for local pharmacokinetic interaction with modafinil in neural cells. | 2012 | Eur Arch Psychiatry Clin Neurosci | pmid:22434147 |
Vendrell D et al. | Accumulation and depletion kinetics of erythromycin in rainbow trout (Oncorhynchus mykiss). | 2012 | Prev. Vet. Med. | pmid:22436556 |
Martins ER et al. | Dominance of serotype Ia among group B Streptococci causing invasive infections in nonpregnant adults in Portugal. | 2012 | J. Clin. Microbiol. | pmid:22219307 |
Chen CM | Erythromycin for the treatment of feeding intolerance in preterm infants. | 2012 | Pediatr Neonatol | pmid:22348487 |
Ng YY et al. | Efficacy of intermediate-dose oral erythromycin on very low birth weight infants with feeding intolerance. | 2012 | Pediatr Neonatol | pmid:22348492 |
Yoon SB et al. | The effect of exenatide and erythromycin on postprandial symptoms and their relation to gastric functions. | 2012 | Digestion | pmid:22354133 |
Golparian D et al. | In vitro activity of the new fluoroketolide solithromycin (CEM-101) against a large collection of clinical Neisseria gonorrhoeae isolates and international reference strains, including those with high-level antimicrobial resistance: potential treatment option for gonorrhea? | 2012 | Antimicrob. Agents Chemother. | pmid:22354296 |
Devlin MJ et al. | Gastric emptying and symptoms of bulimia nervosa: effect of a prokinetic agent. | 2012 | Physiol. Behav. | pmid:22361261 |
Chini P et al. | Effect of azithromycin on small bowel motility in patients with gastrointestinal dysmotility. | 2012 | Scand. J. Gastroenterol. | pmid:22364597 |
Gazzola S et al. | Assessment of tetracycline and erythromycin resistance transfer during sausage fermentation by culture-dependent and -independent methods. | 2012 | Food Microbiol. | pmid:22365347 |
Palumbo Piccionello A et al. | Synthesis and preliminary antibacterial evaluation of Linezolid-like 1,2,4-oxadiazole derivatives. | 2012 | Eur J Med Chem | pmid:22365410 |
Pešić D et al. | Design, synthesis, and in vitro activity of novel 2'-O-substituted 15-membered azalides. | 2012 | J. Med. Chem. | pmid:22380766 |
Shore EM and Yudin MH | Choice of antibiotic for group B streptococcus in women in labour based on antibiotic sensitivity testing. | 2012 | J Obstet Gynaecol Can | pmid:22385665 |
Ullrich K et al. | Neuroretinitis following bull ant sting. | 2012 | BMJ Case Rep | pmid:22865803 |
Pollett S et al. | Campylobacter antimicrobial resistance in Peru: a ten-year observational study. | 2012 | BMC Infect. Dis. | pmid:22898609 |
Pinto A et al. | 6-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective. | 2012 | Org. Lett. | pmid:22519860 |
Yuzawa S et al. | Role of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases. | 2012 | Biochemistry | pmid:22509729 |
Wang Y et al. | The preferred conformation of erythro- and threo-1,2-difluorocyclododecanes. | 2012 | Beilstein J Org Chem | pmid:23019458 |
Michael M et al. | Docetaxel pharmacokinetics and its correlation with two in vivo probes for cytochrome P450 enzymes: the C(14)-erythromycin breath test and the antipyrine clearance test. | 2012 | Cancer Chemother. Pharmacol. | pmid:21626050 |
Shimizu S et al. | Reactivity of lignin with different composition of aromatic syringyl/guaiacyl structures and erythro/threo side chain structures in β-O-4 type during alkaline delignification: as a basis for the different degradability of hardwood and softwood lignin. | 2012 | J. Agric. Food Chem. | pmid:22694300 |
Chhun S et al. | The cytochrome P-450 2C9/2C19 but not the ABCB1 genetic polymorphism may be associated with the liver cytochrome 3A4 induction by phenytoin. | 2012 | J Clin Psychopharmacol | pmid:22561479 |
Ohene-Agyei T et al. | Mutations in MexB that affect the efflux of antibiotics with cytoplasmic targets. | 2012 | FEMS Microbiol. Lett. | pmid:22568688 |
Chen C et al. | Isolation and characterization of LS1924A, a new analog of emycins. | 2012 | J. Antibiot. | pmid:22569162 |
Mandisodza O et al. | Arcobacter species in diarrhoeal faeces from humans in New Zealand. | 2012 | N. Z. Med. J. | pmid:22522270 |
Gao J et al. | Antibiotic resistance of Streptococcus agalactiae from cows with mastitis. | 2012 | Vet. J. | pmid:22627045 |
He JL et al. | [Distribution of anaerobes in periodontal abscess and its resistance to antibiotics]. | 2012 | Zhonghua Kou Qiang Yi Xue Za Zhi | pmid:23328096 |
Zhou Y et al. | Erythromycin ameliorates cigarette-smoke-induced emphysema and inflammation in rats. | 2012 | Transl Res | pmid:22633097 |
Yu DJ et al. | Cornmeal-induced resistance to ciprofloxacin and erythromycin in enterococci. | 2012 | Chemosphere | pmid:22633859 |
Karlgren M et al. | Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | 2012 | J. Med. Chem. | pmid:22541068 |
Noormohamed A and Fakhr MK | Incidence and antimicrobial resistance profiling of Campylobacter in retail chicken livers and gizzards. | 2012 | Foodborne Pathog. Dis. | pmid:22545960 |
Leung HW et al. | Distribution, fate and risk assessment of antibiotics in sewage treatment plants in Hong Kong, South China. | 2012 | Environ Int | pmid:21450345 |
Pinto TF et al. | Tolerance to enteral nutrition therapy in traumatic brain injury patients. | 2012 | Brain Inj | pmid:22571511 |
Deane AM et al. | Randomized double-blind crossover study to determine the effects of erythromycin on small intestinal nutrient absorption and transit in the critically ill. | 2012 | Am. J. Clin. Nutr. | pmid:22572649 |
Senhorinho GN et al. | Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis. | 2012 | Anaerobe | pmid:22609780 |
Rocco L et al. | Micronucleus test and comet assay for the evaluation of zebrafish genomic damage induced by erythromycin and lincomycin. | 2012 | Environ. Toxicol. | pmid:21384490 |
Giovanetti E et al. | ICESp2905, the erm(TR)-tet(O) element of Streptococcus pyogenes, is formed by two independent integrative and conjugative elements. | 2012 | Antimicrob. Agents Chemother. | pmid:21986826 |
Izumikawa M et al. | JBIR-78 and JBIR-95: phenylacetylated peptides isolated from Kibdelosporangium sp. AK-AA56. | 2012 | J. Nat. Prod. | pmid:22264203 |
Brenciani A et al. | ICESp1116, the genetic element responsible for erm(B)-mediated, inducible resistance to erythromycin in Streptococcus pyogenes. | 2012 | Antimicrob. Agents Chemother. | pmid:23027190 |
Li M et al. | Effect of erythromycin on cigarette-induced histone deacetylase protein expression and nuclear factor-κB activity in human macrophages in vitro. | 2012 | Int. Immunopharmacol. | pmid:22265969 |
PiÄ…tkowska E et al. | The strongest resistance of Staphylococcus aureus to erythromycin is caused by decreasing uptake of the antibiotic into the cells. | 2012 | Cell. Mol. Biol. Lett. | pmid:23001512 |
Leiding JW et al. | Successful sirolimus graded dose challenge in an erythromycin-allergic patient. | 2012 | Ann. Allergy Asthma Immunol. | pmid:23010239 |
El Hafidi N et al. | [Mycoplasma pneumoniae encephalitis associated with basal ganglia necrosis]. | 2012 | Rev. Neurol. (Paris) | pmid:22244792 |
Brill S et al. | Transforming a drug/H+ antiporter into a polyamine importer by a single mutation. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23035252 |
Tolosa L et al. | Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. | 2012 | Toxicol. Sci. | pmid:22331495 |
Kou X et al. | Synthesis, characterization and adsorption behavior of molecularly imprinted nanospheres for erythromycin using precipitation polymerization. | 2012 | J Nanosci Nanotechnol | pmid:23035481 |
Ashour S and Bayram R | Novel spectrophotometric method for determination of some macrolide antibiotics in pharmaceutical formulations using 1,2-naphthoquinone-4-sulphonate. | 2012 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:23041925 |