erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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LEE PP et al. | [CASE OF POLIO-LIKE DISEASE DUE TO COXSACKIE A 7 VIRUS]. | 1964 Jul-Sep | Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi | pmid:14213951 |
Peng CF and Chen TS | In vitro activity of midecamycin against Staphylococcus aureus. | 1979 | Zhonghua Min Guo Wei Sheng Wu Xue Za Zhi | pmid:583273 |
Tang RB et al. | Campylobacter jejuni enteritis in children. | 1984 | Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi | pmid:6532655 |
Chang JC et al. | In vitro postantibiotic effect of roxithromycin and erythromycin against gram-positive cocci. | 1992 | Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi | pmid:1342645 |
Ding YF et al. | [Study on the molecule epidemiological between resistances of 7 genes interrelated 4 antibiotic to isolated Streptococcus pneumoniae in children]. | 2005 | Zhonghua Liu Xing Bing Xue Za Zhi | pmid:16185459 |
Wen B | [Observation on clinical features and therapy in 4 elderly cases with legionellosis]. | 1991 | Zhonghua Liu Xing Bing Xue Za Zhi | pmid:1863947 |
Ye Y et al. | [Clinic intervention study on urogenital mycoplasma infection of pregnant women]. | 2001 | Zhonghua Liu Xing Bing Xue Za Zhi | pmid:11718071 |
Xiong Y et al. | [Study on the molecular epidemiology of Streptococcus suis type 2 from healthy pigs in Guangxi]. | 2007 | Zhonghua Liu Xing Bing Xue Za Zhi | pmid:17939392 |
He JL et al. | [Distribution of anaerobes in periodontal abscess and its resistance to antibiotics]. | 2012 | Zhonghua Kou Qiang Yi Xue Za Zhi | pmid:23328096 |
Xiao W et al. | [The imbalance of Th1/Th2 cytokine expression in peripheral blood mononuclear cell from asthmatic patients and the effect of erythromycin on these cytokines]. | 2000 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11778516 |