erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Itoh Z | Motilin and clinical application. | 1997 | Peptides | pmid:9210180 |
| Kluger MT | Erythromycin--a pro-kinetic and pro-arrhythmogenic agent. | 1997 | Anaesth Intensive Care | pmid:9209631 |
| Nakata K et al. | [Suppressive effect of clarithromycin on the production of verotoxin by E. coli O157]. | 1997 | Kansenshogaku Zasshi | pmid:9209125 |
| Nakamura A | [Prevalence of antimicrobial resistance among clinical isolates of Streptococcus pneumoniae in a children's hospital]. | 1997 | Kansenshogaku Zasshi | pmid:9209123 |
| Vagliasindi M | Use of flurythromycin ethylsuccinate in infections of lower airways due to sensitive germs: multicenter comparative study with clarithromycin. | 1997 | Int J Clin Pharmacol Ther | pmid:9208340 |
| Lagasse JP et al. | [Acute reversible pan-dysautonomia: effect of erythromycin on gastrointestinal involvement]. | 1997 | Gastroenterol. Clin. Biol. | pmid:9208000 |
| Gleason PP et al. | Medical outcomes and antimicrobial costs with the use of the American Thoracic Society guidelines for outpatients with community-acquired pneumonia. | 1997 | JAMA | pmid:9207335 |
| Rampe D and Murawsky MK | Blockade of the human cardiac K+ channel Kv1.5 by the antibiotic erythromycin. | 1997 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:9205959 |
| Pacini N et al. | Antimicrobial susceptibility tests on anaerobic oral mixed cultures in periodontal diseases. | 1997 | J. Clin. Periodontol. | pmid:9205919 |
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| Rosser EJ | German shepherd dog pyoderma: a prospective study of 12 dogs. | 1997 Jul-Aug | J Am Anim Hosp Assoc | pmid:9204474 |
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| Koch B et al. | Construction of specific erythromycin resistance mutations in the temperate lactococcal bacteriophage TP901-1 and their use in studies of phage biology. | 1997 | Appl. Environ. Microbiol. | pmid:9172365 |
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| Somkuti GA et al. | Molecular properties of the erythromycin resistance plasmid pPV141 from Staphylococcus chromogenes. | 1997 | Plasmid | pmid:9169203 |
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| Lin JC and Quasny HA | QT prolongation and development of torsades de pointes with the concomitant administration of oral erythromycin base and quinidine. | 1997 May-Jun | Pharmacotherapy | pmid:9165570 |
| Cheng CL et al. | Steady-state pharmacokinetics of delavirdine in HIV-positive patients: effect on erythromycin breath test. | 1997 | Clin. Pharmacol. Ther. | pmid:9164415 |
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| Sugihara E | Effect of macrolide antibiotics on neutrophil function in human peripheral blood. | 1997 | Kansenshogaku Zasshi | pmid:9164088 |
| Hessler PE et al. | Isolation of isoflavones from soy-based fermentations of the erythromycin-producing bacterium Saccharopolyspora erythraea. | 1997 | Appl. Microbiol. Biotechnol. | pmid:9163954 |
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| Carroll KC et al. | Susceptibility of beta-hemolytic streptococci to nine antimicrobial agents among four medical centers in Salt Lake City, Utah, USA. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9154408 |