erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Schreiner A | Pathogenicity of Branhamella catarrhalis. | 1984 | Acta Otolaryngol Suppl | pmid:6333774 |
Sundberg L et al. | The effect of erythromycin on the nasopharyngeal pathogens in children with secretory otitis media. | 1984 Mar-Apr | Acta Otolaryngol. | pmid:6609521 |
Björkwall T | Local treatment with antibiotics in cases of maxillary sinusitis. | 1966 | Acta Otolaryngol. | pmid:5992657 |
Axelsson A et al. | Treatment of acute maxillary sinusitis. IV. Ampicillin, cephradine and erythromycinestolate with and without irrigation. | 1975 May-Jun | Acta Otolaryngol. | pmid:1155056 |
Palva T et al. | Effect of erythromycin on adenoid bacteria. | 1986 Mar-Apr | Acta Otolaryngol. | pmid:3486544 |
Freijd A and Rynnel-Dagöö B | Isolation of nasopharyngeal beta-lactamase producing Haemophilus influenzae, in relation to antibiotic treatment of acute otitis media in infants. | 1983 Mar-Apr | Acta Otolaryngol. | pmid:6404124 |
Liu J et al. | Inhibitory effect of erythromycin on ion transport by stria vascularis and vestibular dark cells. | 1996 | Acta Otolaryngol. | pmid:8831844 |
Cervin A | The anti-inflammatory effect of erythromycin and its derivatives, with special reference to nasal polyposis and chronic sinusitis. | 2001 | Acta Otolaryngol. | pmid:11270500 |
Melon J and Reginster M | [Passage into normal salivary, lacrimal and nasal secretions of ampicillin and erythromycin administered intramuscularly]. | 1976 | Acta Otorhinolaryngol Belg | pmid:1028340 |
Hassid S | [Otitis media caused by Mycoplasma pneumoniae]. | 1985 | Acta Otorhinolaryngol Belg | pmid:3938913 |