erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Rhinitis D012220 10 associated lipids
Skin Ulcer D012883 6 associated lipids
Heart Diseases D006331 8 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Multiple Myeloma D009101 13 associated lipids
Quadriplegia D011782 4 associated lipids
Pain, Postoperative D010149 13 associated lipids
Porphyrias D011164 2 associated lipids
Femoral Fractures D005264 7 associated lipids
Hematuria D006417 13 associated lipids
Labyrinth Diseases D007759 3 associated lipids
Weight Gain D015430 101 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Endocarditis, Bacterial D004697 5 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Leukemia P388 D007941 43 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Obesity D009765 29 associated lipids
Bradycardia D001919 13 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Intraoperative Complications D007431 5 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Eye Diseases D005128 12 associated lipids
Salpingitis D012488 2 associated lipids
Leukemia D007938 74 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Fractures, Open D005597 3 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Crohn Disease D003424 12 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Cholestasis D002779 23 associated lipids
Sinusitis D012852 9 associated lipids
Glomerulonephritis D005921 35 associated lipids
Sepsis D018805 11 associated lipids
Nervous System Diseases D009422 37 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Ataxia D001259 20 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Cross Infection D003428 9 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Wound Infection D014946 12 associated lipids
Bacteriuria D001437 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Pérez RA et al. Analysis of macrolide antibiotics in water by magnetic solid-phase extraction and liquid chromatography-tandem mass spectrometry. 2017 J Pharm Biomed Anal pmid:28858671
Zankari E et al. PointFinder: a novel web tool for WGS-based detection of antimicrobial resistance associated with chromosomal point mutations in bacterial pathogens. 2017 J. Antimicrob. Chemother. pmid:29091202
Giguère S et al. Antimicrobial Resistance in . 2017 Microbiol Spectr pmid:29052538
Liu J et al. Interaction of erythromycin and ketoconazole on the neurological, biochemical and behavioral responses in crucian carp. 2017 Environ. Toxicol. Pharmacol. pmid:28802958
Lee JK et al. Changes in the Serotype Distribution among Antibiotic Resistant Carriage Streptococcus pneumoniae Isolates in Children after the Introduction of the Extended-Valency Pneumococcal Conjugate Vaccine. 2017 J. Korean Med. Sci. pmid:28776337
Jakkidi M et al. An illusion of septic shock: acute generalised exanthematous pustulosis with multiorgan dysfunction. 2017 BMJ Case Rep pmid:28768672
Jeong S et al. Combined photodynamic and antibiotic therapy for skin disorder via lipase-sensitive liposomes with enhanced antimicrobial performance. 2017 Biomaterials pmid:28697465
Lamari F et al. Assessment of the correlation among antibiotic resistance, adherence to abiotic and biotic surfaces, invasion and cytotoxicity of Pseudomonas aeruginosa isolated from diseased gilthead sea bream. 2017 Colloids Surf B Biointerfaces pmid:28697438
Kasetty G et al. The Nonantibiotic Macrolide EM703 Improves Survival in a Model of Quinolone-Treated Pseudomonas aeruginosa Airway Infection. 2017 Antimicrob. Agents Chemother. pmid:28652240
Di Sante L et al. pHTβ-promoted mobilization of non-conjugative resistance plasmids from Enterococcus faecium to Enterococcus faecalis. 2017 J. Antimicrob. Chemother. pmid:28645197
Ramos CJ and Antonetti DA The role of small GTPases and EPAC-Rap signaling in the regulation of the blood-brain and blood-retinal barriers. 2017 Tissue Barriers pmid:28632993
Sader HS et al. Antimicrobial Susceptibility Trends among Staphylococcus aureus Isolates from U.S. Hospitals: Results from 7 Years of the Ceftaroline (AWARE) Surveillance Program, 2010 to 2016. 2017 Antimicrob. Agents Chemother. pmid:28630196
Post A et al. Antibiotic susceptibility profiles among Campylobacter isolates obtained from international travelers between 2007 and 2014. 2017 Eur. J. Clin. Microbiol. Infect. Dis. pmid:28623550
Gonser LI et al. Systemic therapy of ocular and cutaneous rosacea in children. 2017 J Eur Acad Dermatol Venereol pmid:28621909
Wang HK et al. Clinical features and molecular characteristics of childhood community-associated methicillin-resistant Staphylococcus aureus infection in a medical center in northern Taiwan, 2012. 2017 BMC Infect. Dis. pmid:28679429
Haynes KM et al. Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli. 2017 J. Med. Chem. pmid:28650638
Dalal A et al. Interventions for the prevention of recurrent erysipelas and cellulitis. 2017 Cochrane Database Syst Rev pmid:28631307
Štšepetova J et al. Assessment of phenotypic and genotypic antibiotic susceptibility of vaginal Lactobacillus sp. 2017 J. Appl. Microbiol. pmid:28574626
Tanaka Y et al. Applicability of ribosome engineering to vitamin B12 production by Propionibacterium shermanii. 2017 Biosci. Biotechnol. Biochem. pmid:28532245
Demczuk WHB et al. Phylogenetic analysis of emergent Streptococcus pneumoniae serotype 22F causing invasive pneumococcal disease using whole genome sequencing. 2017 PLoS ONE pmid:28531208
Cheled-Shoval S et al. From Cell to Beak: In-Vitro and In-Vivo Characterization of Chicken Bitter Taste Thresholds. 2017 Molecules pmid:28513558
Sato T et al. Mycoplasma bovis isolates from dairy calves in Japan have less susceptibility than a reference strain to all approved macrolides associated with a point mutation (G748A) combined with multiple species-specific nucleotide alterations in 23S rRNA. 2017 Microbiol. Immunol. pmid:28504455
Wozniak A et al. Importance of adhesins in the recurrence of pharyngeal infections caused by Streptococcus pyogenes. 2017 J. Med. Microbiol. pmid:28463664
Pavlova A et al. Toward the rational design of macrolide antibiotics to combat resistance. 2017 Chem Biol Drug Des pmid:28419786
Szczepanska B et al. Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from children and environmental sources in urban and suburban areas. 2017 BMC Microbiol. pmid:28376713
Mingmongkolchai S and Panbangred W In vitro evaluation of candidate Bacillus spp. for animal feed. 2017 J. Gen. Appl. Microbiol. pmid:28331163
Attaran B et al. Effect of biofilm formation by clinical isolates of on the efflux-mediated resistance to commonly used antibiotics. 2017 World J. Gastroenterol. pmid:28275296
Nowakiewicz A et al. Determination of antimicrobial resistance of Enterococcus strains isolated from pigs and their genotypic characterization by method of amplification of DNA fragments surrounding rare restriction sites (ADSRRS fingerprinting). 2017 J. Med. Microbiol. pmid:28260584
Hodge S et al. Nonantibiotic macrolides restore airway macrophage phagocytic function with potential anti-inflammatory effects in chronic lung diseases. 2017 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:28258107
Lee JH et al. Genetic Diversity and Antibiotic Resistance of Enterococcus faecalis Isolates from Traditional Korean Fermented Soybean Foods. 2017 J. Microbiol. Biotechnol. pmid:28237994
Descours G et al. Ribosomal Mutations Conferring Macrolide Resistance in Legionella pneumophila. 2017 Antimicrob. Agents Chemother. pmid:28069647
Wei L et al. Transformation of erythromycin during secondary effluent soil aquifer recharging: Removal contribution and degradation path. 2017 J Environ Sci (China) pmid:28115128
Koryakina I et al. Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering. 2017 ACS Chem. Biol. pmid:28103677
Sugimoto N et al. Invasive pneumococcal disease caused by mucoid serotype 3 Streptococcus pneumoniae: a case report and literature review. 2017 BMC Res Notes pmid:28057059
Liu J et al. Modulation of erythromycin-induced biochemical responses in crucian carp by ketoconazole. 2017 Environ Sci Pollut Res Int pmid:28004371
Hillitt KL et al. Antimicrobial activity of Manuka honey against antibiotic-resistant strains of the cell wall-free bacteria Ureaplasma parvum and Ureaplasma urealyticum. 2017 Lett. Appl. Microbiol. pmid:27992658
Numanović F et al. Presence and resistance of Streptococcus agalactiae in vaginal specimens of pregnant and adult non-pregnant women and association with other aerobic bacteria. 2017 Med Glas (Zenica) pmid:27917849
Waites KB et al. In Vitro Activities of Lefamulin and Other Antimicrobial Agents against Macrolide-Susceptible and Macrolide-Resistant Mycoplasma pneumoniae from the United States, Europe, and China. 2017 Antimicrob. Agents Chemother. pmid:27855075
Parthasarathy G et al. Relationship Between Gastric Emptying and Diurnal Glycemic Control in Type 1 Diabetes Mellitus: A Randomized Trial. 2017 J. Clin. Endocrinol. Metab. pmid:27880079
Creti R et al. Neonatal Group B Streptococcus Infections: Prevention Strategies, Clinical and Microbiologic Characteristics in 7 Years of Surveillance. 2017 Pediatr. Infect. Dis. J. pmid:27870810
Zhang W et al. Isolation and characterization of a high-efficiency erythromycin A-degrading Ochrobactrum sp. strain. 2017 Mar. Pollut. Bull. pmid:27863881
Li B et al. Antimicrobial Resistance of Campylobacter Species Isolated from Broilers in Live Bird Markets in Shanghai, China. 2017 Foodborne Pathog. Dis. pmid:27854542
Shrivastav AM et al. Highly sensitive and selective erythromycin nanosensor employing fiber optic SPR/ERY imprinted nanostructure: Application in milk and honey. 2017 Biosens Bioelectron pmid:27825873
Liu J et al. Engineering of an Lrp family regulator SACE_Lrp improves erythromycin production in Saccharopolyspora erythraea. 2017 Metab. Eng. pmid:27794466
Kullin B et al. Toxin A-negative toxin B-positive ribotype 017 Clostridium difficile is the dominant strain type in patients with diarrhoea attending tuberculosis hospitals in Cape Town, South Africa. 2017 Eur. J. Clin. Microbiol. Infect. Dis. pmid:27696234
Pavlović D et al. Synthesis of novel 15-membered 8a-azahomoerythromycin A acylides: Consequences of structural modification at the C-3 and C-6 position on antibacterial activity. 2017 Eur J Med Chem pmid:27657812
Lim SK et al. Macrolide resistance mechanisms and virulence factors in erythromycin-resistant Campylobacter species isolated from chicken and swine feces and carcasses. 2017 J. Vet. Med. Sci. pmid:27593510
Zhou X et al. Erythromycin attenuates metalloprotease/anti-metalloprotease imbalance in cigarette smoke-induced emphysema in rats via the mitogen-activated protein kinase/nuclear factor-κB activation pathway. 2017 Mol Med Rep pmid:28358431
Marlow N et al. The ORACLE Children Study: educational outcomes at 11 years of age following antenatal prescription of erythromycin or co-amoxiclav. 2017 Arch. Dis. Child. Fetal Neonatal Ed. pmid:27515985
Naimi HM et al. Determination of antimicrobial susceptibility patterns in Staphylococcus aureus strains recovered from patients at two main health facilities in Kabul, Afghanistan. 2017 BMC Infect. Dis. pmid:29187146
Ricker EB and Nuxoll E Synergistic effects of heat and antibiotics on Pseudomonas aeruginosa biofilms. 2017 Biofouling pmid:29039211
Bitew A et al. Species distribution and antibiotic susceptibility profile of bacterial uropathogens among patients complaining urinary tract infections. 2017 BMC Infect. Dis. pmid:28962545
Öksüz L and Gürler N [Serotype distribution and antibiotic resistance of Streptococcus pneumoniae strains isolated from the adult patients in a Turkish üniversity hospital]. 2017 Mikrobiyol Bul pmid:28929957
Pan M and Chu LM Transfer of antibiotics from wastewater or animal manure to soil and edible crops. 2017 Environ. Pollut. pmid:28866424
Wekselman I et al. The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. 2017 Structure pmid:28689968
Truong-Bolduc QC et al. Transcriptional Regulator TetR21 Controls the Expression of the Staphylococcus aureus LmrS Efflux Pump. 2017 Antimicrob. Agents Chemother. pmid:28584148
Blackwell GA and Hall RM The Determinant and the Genes in Acinetobacter Plasmids Are Each Part of Discrete Modules Flanked by Inversely Oriented p (XerC-XerD) Sites. 2017 Antimicrob. Agents Chemother. pmid:28533235
Dolberg AM and Reichl S Activity of Multidrug Resistance-Associated Proteins 1-5 (MRP1-5) in the RPMI 2650 Cell Line and Explants of Human Nasal Turbinate. 2017 Mol. Pharm. pmid:28291371
Massip C et al. Macrolide resistance in Legionella pneumophila: the role of LpeAB efflux pump. 2017 J. Antimicrob. Chemother. pmid:28137939
García-Iglesias P et al. Management of non variceal upper gastrointestinal bleeding: position statement of the Catalan Society of Gastroenterology. 2017 Gastroenterol Hepatol pmid:28109636
Argemi X et al. VISLISI trial, a prospective clinical study allowing identification of a new metalloprotease and putative virulence factor from Staphylococcus lugdunensis. 2017 Clin. Microbiol. Infect. pmid:28017792
Ksia S et al. Molecular Characteristics of Erythromycin-Resistant Streptococcus pyogenes Strains Isolated from Children Patients in Tunis, Tunisia. 2017 Microb. Drug Resist. pmid:27991848
Pfaller MA et al. Ceftaroline Activity Against Multidrug-Resistant Streptococcus pneumoniae from U.S. Medical Centers (2014) and Molecular Characterization of a Single Ceftaroline Nonsusceptible Isolate. 2017 Microb. Drug Resist. pmid:27918694
Chang KH et al. Comparison of antibiotic regimens in preterm premature rupture of membranes: neonatal morbidity and 2-year follow-up of neurologic outcome. 2017 J. Matern. Fetal. Neonatal. Med. pmid:27687157
Yi M et al. Functional characterization of a common CYP4F11 genetic variant and identification of functionally defective CYP4F11 variants in erythromycin metabolism and 20-HETE synthesis. 2017 Arch. Biochem. Biophys. pmid:28347661
Duelge KJ et al. An LC-MS/MS method for the determination of antibiotic residues in distillers grains. 2017 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:28415016
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Zhou Z et al. Combination of Erythromycin and Curcumin Alleviates Induced Osteomyelitis in Rats. 2017 Front Cell Infect Microbiol pmid:28884090
Peng Z et al. Genomic insights into the pathogenicity and environmental adaptability of Enterococcus hirae R17 isolated from pork offered for retail sale. 2017 Microbiologyopen pmid:28799224
Zheng PX et al. Highly prevalent emmSTG840.0 and emmSTC839.0 types of erythromycin non-susceptible group G Streptococcus isolated from bacteremia in southern Taiwan. 2017 J Microbiol Immunol Infect pmid:28711431
Abreu AC et al. Looking to nature for a new concept in antimicrobial treatments: isoflavonoids from Cytisus striatus as antibiotic adjuvants against MRSA. 2017 Sci Rep pmid:28630440
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Tay JH et al. Regiodivergent Glycosylations of 6-Deoxy-erythronolide B and Oleandomycin-Derived Macrolactones Enabled by Chiral Acid Catalysis. 2017 J. Am. Chem. Soc. pmid:28627172
Hong M et al. C-assisted metabolomics analysis reveals the positive correlation between specific erythromycin production rate and intracellular propionyl-CoA pool size in Saccharopolyspora erythraea. 2017 Bioprocess Biosyst Eng pmid:28567527
Na HK et al. Erythromycin infusion prior to endoscopy for acute nonvariceal upper gastrointestinal bleeding: a pilot randomized controlled trial. 2017 Korean J. Intern. Med. pmid:28352063
Wang B et al. Acid or erythromycin stress significantly improves transformation efficiency through regulating expression of DNA binding proteins in Lactococcus lactis F44. 2017 J. Dairy Sci. pmid:28987584
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Zhao L et al. Occurrence of erythromycin and its degradation products residues in honey. Validation of an analytical method. 2017 J Sep Sci pmid:28121061
Dreno B et al. Skin microbiome and acne vulgaris: Staphylococcus, a new actor in acne. 2017 Exp. Dermatol. pmid:28094874
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Tang C et al. The incidence and drug resistance of Clostridium difficile infection in Mainland China: a systematic review and meta-analysis. 2016 Sci Rep pmid:27897206
Hu P et al. Erythromycin triggers intussusception in a pediatric patient with Henoch-Schönlein purpura. 2016 Turk J Gastroenterol pmid:27782898
Heß S and Gallert C Growth Behavior of E. coli, Enterococcus and Staphylococcus Species in the Presence and Absence of Sub-inhibitory Antibiotic Concentrations: Consequences for Interpretation of Culture-Based Data. 2016 Microb. Ecol. pmid:27220972
de Jesus Gaffney V et al. Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water. 2016 Environ. Toxicol. Chem. pmid:27061931
Barbanti F et al. Transfer of Clostridium difficile Genetic Elements Conferring Resistance to Macrolide-Lincosamide-Streptogramin B (MLSB) Antibiotics. 2016 Methods Mol. Biol. pmid:27507342
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Burr LD et al. Macrolide Treatment Inhibits Pseudomonas aeruginosa Quorum Sensing in Non-Cystic Fibrosis Bronchiectasis. An Analysis from the Bronchiectasis and Low-Dose Erythromycin Study Trial. 2016 Ann Am Thorac Soc pmid:27464029
Aydin S Enhanced biodegradation of antibiotic combinations via the sequential treatment of the sludge resulting from pharmaceutical wastewater treatment using white-rot fungi Trametes versicolor and Bjerkandera adusta. 2016 Appl. Microbiol. Biotechnol. pmid:27033714
Hsieh PF et al. The Klebsiella pneumoniae YfgL (BamB) lipoprotein contributes to outer membrane protein biogenesis, type-1 fimbriae expression, anti-phagocytosis, and in vivo virulence. 2016 Virulence pmid:27029012
Baker KR et al. A High-Throughput Approach To Identify Compounds That Impair Envelope Integrity in Escherichia coli. 2016 Antimicrob. Agents Chemother. pmid:27458225
Juda M et al. The prevalence of genotypes that determine resistance to macrolides, lincosamides, and streptogramins B compared with spiramycin susceptibility among erythromycin-resistant Staphylococcus epidermidis. 2016 Mem. Inst. Oswaldo Cruz pmid:27008373
Lewis K et al. The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials. 2016 Crit Care pmid:27527069
Pierattini EC et al. Morpho-physiological response of Populus alba to erythromycin: A timeline of the health status of the plant. 2016 Sci. Total Environ. pmid:27366984
He HJ et al. Erythromycin resistance features and biofilm formation affected by subinhibitory erythromycin in clinical isolates of Staphylococcus epidermidis. 2016 J Microbiol Immunol Infect pmid:24768213
Bhadra PK et al. Enhancement of the properties of a drug by mono-deuteriation: reduction of acid-catalysed formation of a gut-motilide enol ether from 8-deuterio-erythromycin B. 2016 Org. Biomol. Chem. pmid:27273525
Rodrigues S et al. Acute and chronic effects of erythromycin exposure on oxidative stress and genotoxicity parameters of Oncorhynchus mykiss. 2016 Sci. Total Environ. pmid:26760278
Cheng Y et al. Comparative study between macrolide regulatory proteins MphR(A) and MphR(E) in ligand identification and DNA binding based on the rapid in vitro detection system. 2016 Anal Bioanal Chem pmid:26753969
Arenz S et al. A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest. 2016 Nat Commun pmid:27380950
Berg L et al. [Cutaneous diphtheria after a minor injury in Sri Lanka]. 2016 Hautarzt pmid:26525966
Takahashi T et al. Epidemiological study of erythromycin-resistant Streptococcus pyogenes from Korea and Japan by emm genotyping and multilocus sequence typing. 2016 Ann Lab Med pmid:26522753