erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Rhinitis D012220 10 associated lipids
Skin Ulcer D012883 6 associated lipids
Heart Diseases D006331 8 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Multiple Myeloma D009101 13 associated lipids
Quadriplegia D011782 4 associated lipids
Pain, Postoperative D010149 13 associated lipids
Porphyrias D011164 2 associated lipids
Femoral Fractures D005264 7 associated lipids
Hematuria D006417 13 associated lipids
Labyrinth Diseases D007759 3 associated lipids
Weight Gain D015430 101 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Endocarditis, Bacterial D004697 5 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Leukemia P388 D007941 43 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Obesity D009765 29 associated lipids
Bradycardia D001919 13 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Intraoperative Complications D007431 5 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Eye Diseases D005128 12 associated lipids
Salpingitis D012488 2 associated lipids
Leukemia D007938 74 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Fractures, Open D005597 3 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Crohn Disease D003424 12 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Cholestasis D002779 23 associated lipids
Sinusitis D012852 9 associated lipids
Glomerulonephritis D005921 35 associated lipids
Sepsis D018805 11 associated lipids
Nervous System Diseases D009422 37 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Ataxia D001259 20 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Cross Infection D003428 9 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Wound Infection D014946 12 associated lipids
Bacteriuria D001437 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Lakritz J et al. Comparison of microbiologic and high-performance liquid chromatography assays to determine plasma concentrations, pharmacokinetics, and bioavailability of erythromycin base in plasma of foals after intravenous or intragastric administration. 1999 Am. J. Vet. Res. pmid:10211682
McConnell SA and Amsden GW Review and comparison of advanced-generation macrolides clarithromycin and dirithromycin. 1999 Pharmacotherapy pmid:10212011
Betriu C et al. Incidence of erythromycin resistance in Streptococcus pyogenes: a 10-year study. 1999 Diagn. Microbiol. Infect. Dis. pmid:10212752
Dubois J and St-Pierre C In vitro activity of gatifloxacin, compared with ciprofloxacin, clarithromycin, erythromycin, and rifampin, against Legionella species. 1999 Diagn. Microbiol. Infect. Dis. pmid:10212753
Biedenbach DJ et al. Comparative in vitro evaluation of dirithromycin tested against recent clinical isolates of Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae, including effects of medium supplements and test conditions on MIC results. 1999 Diagn. Microbiol. Infect. Dis. pmid:10212755
Kim RB et al. Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein. 1999 Pharm. Res. pmid:10213372
Torii A [Effective treatment in combination with erythromycin and cisapride for chronic idiopathic intestinal pseudo-obstruction (CIIP)]. 1999 Nihon Shokakibyo Gakkai Zasshi pmid:10214084
Bercault N and Linassier P [The value of sepsis isolation to diminish the spread of multidrug-resistant bacteria in intensive care. Consequences on the incidence of nosocomial infections]. 1999 Rev Med Interne pmid:10220829
Perez-Trallero E et al. Clonal differences among erythromycin-resistant Streptococcus pyogenes in Spain. 1999 Mar-Apr Emerging Infect. Dis. pmid:10221875
Jackson LA et al. Lack of association between first myocardial infarction and past use of erythromycin, tetracycline, or doxycycline. 1999 Mar-Apr Emerging Infect. Dis. pmid:10221884
Bassetti M et al. Streptococcus pyogenes erythromycin resistance in Italy. 1999 Mar-Apr Emerging Infect. Dis. pmid:10221991
Siedlik PH et al. Erythromycin coadministration increases plasma atorvastatin concentrations. 1999 J Clin Pharmacol pmid:10234598
Tran JQ et al. Assessment of the potential pharmacokinetic and pharmacodynamic interactions between erythromycin and argatroban. 1999 J Clin Pharmacol pmid:10234600
Morris LA and Kanouse DE Consumer reactions to differing amounts of written drug information. 1980 Jul-Aug Drug Intell Clin Pharm pmid:10247887
Bystedt H et al. Concentrations of azidocillin, erythromycin, doxycycline and clindamycin in human mandibular bone. 1978 Int J Oral Surg pmid:102599
Klein JO Middle ear disease in children. 1976 Hosp Pract pmid:1026633
Gregotti C et al. [Effects of phenobarbital on the hepatic microsome metabolism of erythromycin in rats]. 1976 Boll. Soc. Ital. Biol. Sper. pmid:1027460
Melon J and Reginster M [Passage into normal salivary, lacrimal and nasal secretions of ampicillin and erythromycin administered intramuscularly]. 1976 Acta Otorhinolaryngol Belg pmid:1028340
Rosenthal AL et al. Polyacrylic bone cement containing erythromycin and colistin. I. In vitro bacteriological activity and diffusion properties of erythromycin, colistin and erythromycin/colistin comibination. 1976 J. Int. Med. Res. pmid:1028631
Stille W [Legionnaire's disease]. 1978 MMW Munch Med Wochenschr pmid:102952